Lymph node disease with lymphocytic abnormal chromatin clumping in a myelodysplastic/myeloproliferative syndrome.

abstract：AIM:To ascertain the views of Scottish hospital laboratory users on aspects of regional and supraregional biochemical services offered by the Institute of Biochemistry at Glasgow Royal Infirmary. METHODS:A questionnaire was circulated asking questions or inviting opinions under various headings, including current patt...

journal_title：Journal of clinical pathology

authors： Murphy MJ,Dryburgh FJ,Shepherd J

更新日期：1994-05-01 00:00:00

abstract：AIM:Primary biliary cirrhosis (PBC) is characterised by antimitochondrial antibody against the pyruvate dehydrogenase complex (PDC) and chronic non-suppurative destructive cholangitis (CNSDC). Pyruvate oxidation to acetyl-CoA by PDC is a key step in the glycolytic system. Oestrogen-related receptor-α (ERRα) is function...

journal_title：Journal of clinical pathology

authors： Harada K,Kakuda Y,Sato Y,Ikeda H,Shimoda S,Yamamoto Y,Inoue H,Ohta H,Kasashima S,Kawashima A,Nakanuma Y

更新日期：2014-05-01 00:00:00

abstract：:Methods of speciating Candida isolates from clinical specimens are described and the necessity of speciation is emphasized. Differences in susceptibility of C. albicans and C. tropicalis to amphotericin B were observed and the implications of this in relation to treatment with amphotericin B and the development of res...

journal_title：Journal of clinical pathology

authors： Stieritz DD,Law EJ,Holder IA

更新日期：1973-06-01 00:00:00

abstract：OBJECTIVE:Acute B lymphoblastic leukaemia (B-ALL) is the most common type of childhood malignancy worldwide but little is known of its origin. Recently, many studies showed both a high incidence of Epstein-Barr virus (EBV) infection and high levels of CD4+CD25+Foxp3+(Treg cells) in children with B-ALL. In our study, we...

journal_title：Journal of clinical pathology

authors： Ateyah ME,Hashem ME,Abdelsalam M

更新日期：2017-02-01 00:00:00

abstract：:Pathological findings are described in four cases of a new aminoaciduria in which homocystine is excreted in the urine. All the patients were mentally retarded children. Three of them presented diagnostic features of Marfan's syndrome. Necropsy on one case and biopsy findings in the others are described. Fatty change ...

journal_title：Journal of clinical pathology

authors： GIBSON JB,CARSON NA,NEILL DW

更新日期：1964-07-01 00:00:00

abstract：AIMS:Sentinel lymph node (SLN) biopsy is the preferred surgical technique for staging the axilla in clinically node-negative breast cancer. Accurate intraoperative staging allows for the immediate performance of an axillary clearance in node-positive patients. We assessed the Metasin assay for the intraoperative analys...

journal_title：Journal of clinical pathology

authors： Smith GJ,Hodges E,Markham H,Zhang S,Cutress RI

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:The TNM classification for renal cell cancer (RCC) should accurately predict and assign prognostic information for patients. In this study the recent 2010 revision to the TNM classification was compared with the previous 2002 classification with regard to survival outcomes. METHODS:All patients having radic...

journal_title：Journal of clinical pathology

authors： Veeratterapillay R,Simren R,El-Sherif A,Johnson MI,Soomro N,Heer R

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Ewing's sarcoma and peripheral primitive neuroectodermal tumour (pPNET) are now regarded as two morphological ends of a spectrum of neoplasms, characterised by a t(11;22) or other related chromosomal translocation involving the EWS gene on chromosome 22 and referred to as Ewing family of tumours (EFTs). EFTs...

journal_title：Journal of clinical pathology

authors： McCluggage WG,Sumathi VP,Nucci MR,Hirsch M,Dal Cin P,Wells M,Flanagan AM,Fisher C

更新日期：2007-06-01 00:00:00

abstract：:A method is described for the estimation of serum free fatty acids based on the ultramicro method of Novák. The difficulty of obtaining an accurate standard graph has been overcome and the interfering effects of phospholipids have been reduced. The method is simple to perform and gives accurate, precise results in 50 ...

journal_title：Journal of clinical pathology

authors： Elphick MC

更新日期：1968-09-01 00:00:00

abstract：:Five cases of malignant histiocytosis of the intestine and one case of true histiocytic lymphoma were studied using immunohistological techniques. In paraffin sections tumour cells in all cases were shown to contain alpha-1-antitrypsin and to express the leucocyte common antigen. Four of the five cases of malignant hi...

journal_title：Journal of clinical pathology

authors： Salter DM,Krajewski AS,Dewar AE

更新日期：1986-01-01 00:00:00

abstract：:Using a short series of biochemical tests already in use in many routine laboratories, it is possible to identify strains of the genus Klebsiella and to differentiate K. aerogenes from other types. Marked production of slime is not peculiar to the group and colonial appearance alone is not a satisfactory basis for ide...

journal_title：Journal of clinical pathology

authors： DARRELL JH,HURDLE AD

更新日期：1964-11-01 00:00:00

abstract：INTRODUCTION:Cellular blue naevi (CBN) measure 1-2 cm in diameter and affect the dermis, occasionally extending into the subcutaneous fat. The case of a 14-year-old boy with a giant CBN (GCBN) involving the right half of the face, the jugal mucosa and the lower eyelid with a tumour that had infiltrated the bone and the...

journal_title：Journal of clinical pathology

authors： Bittencourt AL,Monteiro DA,De Pretto OJ

更新日期：2007-01-01 00:00:00

abstract：:Factor VIII-containing materials were administered to four severely affected haemophiliacs twice weekly in doses calculated to raise the factor VIII level to either 15% or 30% of average normal. The pooled results from those patients with statistically similar baseline bleeding frequencies showed a significant reducti...

journal_title：Journal of clinical pathology

authors： Aronstam A,Kirk PJ,McHardy J,Culver-James JW,McLellan DS,Turk P,Rainsford SG,Slattery M

更新日期：1977-01-01 00:00:00

abstract：:The interference of IgM-class rheumatoid factor (RF) in the solid-phase radioimmunoassay (RIA) of rubella virus IgM antibodies was studied. Acute rubella infections did not significantly activate RF. False-positive rubella antibody results were obtained, however, when patients with raised RF levels were tested. If a l...

journal_title：Journal of clinical pathology

authors： Meurman OH,Ziola BR

更新日期：1978-05-01 00:00:00

abstract：:The API 20 STREP system was used to identify 146 known strains from seven species of the genus Listeria, including both pathogenic and environmental strains. The gallery was easy to use and tests, with the exception of leucine arylamidase (LAP) and starch fermentation (AMD), were simple to interpret. Identification to...

journal_title：Journal of clinical pathology

authors： MacGowan AP,Marshall RJ,Reeves DS

更新日期：1989-05-01 00:00:00

abstract：:A rapid technique using a non-radioactive receptor molecule (digoxigenin) for intrahepatic hepatitis B virus (HBV) DNA detection using in situ hybridisation was developed. It can be adapted for use in combination with standard immunohistochemistry for simultaneous detection of both HBV DNA and HBV antigens. The total ...

journal_title：Journal of clinical pathology

authors： Lau JY,Naoumov NV,Alexander GJ,Williams R

更新日期：1991-11-01 00:00:00

abstract：AIMS:To analyse the expression of proteins involved in DNA double strand break detection and repair in the luminal and myoepithelial compartments of benign breast lesions and malignant breast tumours with myoepithelial differentiation. METHODS:Expression of the ataxia telangiectasia (ATM) and p53 proteins was immunohi...

journal_title：Journal of clinical pathology

authors： Angèle S,Jones C,Reis Filho JS,Fulford LG,Treilleux I,Lakhani SR,Hall J

更新日期：2004-11-01 00:00:00

abstract：:Four strains of Corynebacterium diphtheriae were sent to UK participants in the UK National External Microbiological Quality Assessment Scheme, who were asked to examine the strains for toxin production by in vitro methods. Laboratories achieved 162/176 (92%) and 160/175 (91%) correct results with two rapid toxin prod...

journal_title：Journal of clinical pathology

authors： Snell JJ,Demello JV,Gardner PS,Kwantes W,Brooks R

更新日期：1984-07-01 00:00:00

abstract：AIM:To develop a polymerase chain reaction (PCR) for the specific detection of the C protein gene in strains of group B Streptococcus. METHODS:A single primer pair derived from the nucleotide sequence of the IgA binding beta antigen of the C protein complex permitted the specific amplification of a 592 base pair DNA f...

journal_title：Journal of clinical pathology

authors： Mawn JA,Simpson AJ,Heard SR

更新日期：1993-07-01 00:00:00

abstract：AIMS:To determine the potential efficiency of molecular markers specific for neoplastic change--mutations of the K-ras oncogene and the p53 tumour suppressor gene--in diagnosing pancreatic carcinoma. METHODS:Archival cytology samples obtained from 17 patients with established pancreatic carcinoma were assayed for alte...

journal_title：Journal of clinical pathology

authors： van Es JM,Polak MM,van den Berg FM,Ramsoekh TB,Craanen ME,Hruban RH,Offerhaus GJ

更新日期：1995-03-01 00:00:00

abstract：AIMS:To evaluate an indirect immunofluorescence flow cytometry technique in a series of patients with large fetomaternal haemorrhage (FMH). METHODS:Patient samples identified by Kleihauer testing in local laboratories as having FMH > 4 ml were sent for flow cytometric analysis. In a proportion of cases the mothers rec...

journal_title：Journal of clinical pathology

authors： Johnson PR,Tait RC,Austin EB,Shwe KH,Lee D

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:RCAS1 (receptor binding cancer antigen expressed on SiSo cells) is a tumour associated antigen. It is involved in immune evasion by tumour cells, by binding to receptors on cells involved in the immune response, such as T cells and natural killer cells, and inducing apoptosis. High expression of RCAS1 has be...

journal_title：Journal of clinical pathology

authors： Leelawat K,Watanabe T,Nakajima M,Tujinda S,Suthipintawong C,Leardkamolkarn V

更新日期：2003-10-01 00:00:00

abstract：:A woman with peripheral vascular disease developed cytomegalovirus colitis following repair of abdominal aortic aneurysm. Cytomegalovirus colitis developing in an immunocompetent individual may be caused by a breach in the integrity of the mucosal lining of the colon from various causes and should alert the clinician ...

journal_title：Journal of clinical pathology

authors： al Mahdy H

更新日期：1998-06-01 00:00:00

abstract：:The applicability of a recently developed non-radioactive DNA labelling and detection method, which uses the digoxigenin (DIG) enzyme linked immunosorbent assay (ELISA) system, for the detection of viral infections in pathology specimens by in situ hybridisation, was examined. Its efficacy was compared with that of bi...

journal_title：Journal of clinical pathology

authors： Furuta Y,Shinohara T,Sano K,Meguro M,Nagashima K

更新日期：1990-10-01 00:00:00

abstract：:A quantitative histological analysis of the major salivary glands was carried out at necropsy in 28 alcoholics and in a series of age and sex matched controls. The findings were related to the different types of histologically diagnosed liver disease present. Significant quantitative changes of salivary gland structur...

journal_title：Journal of clinical pathology

authors： Scott J,Burns J,Flower EA

更新日期：1988-08-01 00:00:00

abstract：:An antibody was raised against a protein isolated from the cytoplasm of mesothelioma cells. It was subsequently used in an immunoperoxidase procedure on formalin fixed, paraffin embedded tissue sections. A representative sample of benign and malignant tumours from all the systems of the human body was examined. All th...

journal_title：Journal of clinical pathology

authors： Donna A,Betta PG,Bellingeri D,Marchesini A

更新日期：1986-09-01 00:00:00

abstract：:Automation in clinical chemistry is a powerful tool. Like most innovations it is posing many questions as well as resolving some. Its use in population screening has led to questioning the validity of the old system of ;normal values' and to the search for better methods of indicating the significance of laboratory te...

journal_title：Journal of clinical pathology

authors： Wilson JM

更新日期：1973-08-01 00:00:00

abstract：:This paper records the results of the intravenous inoculation of chick embryos with type 5 gonococci and establishes that these strains are pathogenic. ...

journal_title：Journal of clinical pathology

authors： Hafiz S,Jennings R,McEntegart MG,Jephcott AE

更新日期：1978-05-01 00:00:00

abstract：AIMS:To investigate the histopathological features of the synovial lining of the knee following implantation of an artificial cruciate ligament. METHODS:Eighty two patients underwent anterior cruciate ligament reconstruction for chronic, symptomatic instability of the knee. The cruciate ligament was reconstructed with...

journal_title：Journal of clinical pathology

authors： Barry M,Thomas SM,Rees A,Shafighian B,Mowbray MA

更新日期：1995-06-01 00:00:00

abstract：:The need for separate swab transport methods for aerobes and anaerobes may result in inadequate transport of specimens for anaerobic bacteriology. Most microbiology laboratories in Australia rely on Stuart's transport medium to protect anaerobic bacteria. This paper presents a new, simple transport medium (Transport D...

journal_title：Journal of clinical pathology

authors： Alfa M,Lee A

更新日期：1982-05-01 00:00:00