Current trends and problems in health screening.

abstract：AIMS:To establish whether abnormalities in the course of the vertebral artery occur and whether they are relevant to arterial injury associated with head and neck movements. METHODS:Twenty vertebral arteries were carefully dissected at necropsy and abnormalities in course were noted, along with any other bony or carti...

journal_title：Journal of clinical pathology

authors： Johnson CP,Scraggs M,How T,Burns J

更新日期：1995-07-01 00:00:00

abstract：:Two cases of interstitial pneumonia are described. They were characterized by mononuclear cell infiltration of the alveolar walls and protein-rich exudate into the alveolar cavities, with localized hyaline membrane formation. Coxsackie B5 virus was isolated from the lungs of both patients at necropsy. ...

journal_title：Journal of clinical pathology

authors： Flewett TH

更新日期：1965-11-01 00:00:00

abstract：:Experience gained in the last four years concerning the capabilities and limitations of an 8K Elliott 903 (18-bit word) computer with magnetic tape backing store in the routine operation of a clinical chemistry laboratory is described. Designed as a total system, routine operation has latterly had to be confined to da...

journal_title：Journal of clinical pathology

authors： Whitby LG,Simpson D

更新日期：1973-07-01 00:00:00

abstract：:Cytomegalovirus (CMV) is a recognised cause of morbidity and mortality in immunocompromised individuals. This review will concentrate on recent advances in the understanding of the complex interplay between the host and parasite and the pathological consequences of perturbation of the host immune system. The classic v...

journal_title：Journal of clinical pathology

authors： Emery VC

更新日期：2001-02-01 00:00:00

abstract：:A "Centrifichem" centrifugal analyser was found using a double fluorescence/bacterial tracer method to be a source of airborne and surface contamination in the laboratory. The airborne contamination was controlled by a modification incorporating a filter. Ubiquitous surface contamination generally accompanied the proc...

journal_title：Journal of clinical pathology

authors： Kennedy DA,Stevens JF,Horn AN

更新日期：1988-11-01 00:00:00

abstract：AIMS:Periductal angiogenesis in ductal carcinoma in situ is associated with an increased risk of subsequently developing a recurrence. This study aimed to (1) identify the relation between periductal and stromal vascularity and recurrence and (2) determine whether thymidine phosphorylase (TP) is associated with angioge...

journal_title：Journal of clinical pathology

authors： Teo NB,Shoker BS,Jarvis C,Sloane JP,Holcombe C

更新日期：2003-12-01 00:00:00

abstract：:Macroscopic evidence of bruising from human bite marks may be inconclusive and routine histochemical methods of showing extravasated erythrocytes can be unreliable. Leuco patent blue staining, for the presence of peroxidase, Amido black B, a tinctorial staining method for haemoglobin, Perls's reaction for ferric iron ...

journal_title：Journal of clinical pathology

authors： Allison RT,Whittaker DK

更新日期：1990-07-01 00:00:00

abstract：AIMS:To assess A103 (melan-A) immunoreactivity in a range of ovarian sex cord stromal tumours and to evaluate it for the differential diagnosis of other neoplasms. METHODS:Paraffin embedded tissue sections from 45 sex cord stromal tumours and 44 potential histological mimics were examined immunohistochemically using t...

journal_title：Journal of clinical pathology

authors： Stewart CJ,Nandini CL,Richmond JA

更新日期：2000-03-01 00:00:00

abstract：AIMS:The signalling system of phosphoinositides (PIs) is involved in a number of cell and tissue functions including membrane trafficking, ion channel activity, cell cycle, apoptosis, differentiation and cell and tissue polarity. Recently, a role in cell migration was hypothesised for PI and related molecules including...

journal_title：Journal of clinical pathology

authors： Lo Vasco VR,Pacini L,Di Raimo T,D'arcangelo D,Businaro R

更新日期：2011-10-01 00:00:00

abstract：:DNA typing was requested to investigate a presumptive cancer diagnosis error by confirming whether benign and cancerous prostatic tissue in the same presurgical haematoxylin and eosin stained slide belonged to the same person. After independent histological re-examination of the slide by a pathologist, manual slide di...

journal_title：Journal of clinical pathology

authors： Alonso A,Alves C,Suárez-Mier MP,Albarrán C,Pereira L,Fernández de Simón L,Martín P,García O,Gusmão L,Sancho M,Amorim A

更新日期：2005-01-01 00:00:00

abstract：:A method of typing isolates of Proteus mirabilis and Proteus vulgaris is described based on the sensitivity of the organisms to bacteriocine. Twelve standard proteocine producing strains were selected from a large number of isolates tested, and from these liquid proteocine preparations were prepared. The sensitivities...

journal_title：Journal of clinical pathology

authors： Al-Jumaili IJ

更新日期：1975-10-01 00:00:00

abstract：:Liver function was assessed in 38 Edinburgh haemophiliacs. Results before the introduction of NHS intermediate factor VIII concentrate from 1974 onwards were compared with values in 1979. Measurements of serum bile salts in 16 patients as well as conventional liver function tests gave useful evidence of deranged liver...

journal_title：Journal of clinical pathology

authors： Stirling ML,Beckett GJ,Percy-Robb IW

更新日期：1981-01-01 00:00:00

abstract：:HeLa 229 cells were infected with genital tract strains of Chlamydia trachomatis. After incubation for varying times the infected cells were fixed and stained with the fluorescent DNA binding dyes Hoechst 33258 or DAPI for comparison with conventional Giemsa stain. Fluorochrome-treated preparations were examined by in...

journal_title：Journal of clinical pathology

authors： Salari SH,Ward ME

更新日期：1979-11-01 00:00:00

abstract：AIMS:To assess the presence of carcinoma in situ (CIS) in patients with nasopharyngeal carcinoma (NPC) and to see if the number of biopsy sites facilitates detection of CIS. METHODS:Formalin fixed, paraffin wax embedded biopsy specimens (n = 285) from 187 patients with NPC in 1987 were studied for the presence of CIS ...

journal_title：Journal of clinical pathology

authors： Chan CW,Nicholls JM,Sham JS,Dickens P,Choy D

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND:Fungal infection is increasingly recognised as an important cause of morbidity and mortality, especially in immunocompromised patients. Little information exists on laboratory services available and the methods used by general microbiology laboratories to diagnose these important infections. AIM:To investig...

journal_title：Journal of clinical pathology

authors： Hassan IA,Critten P,Isalska B,Denning DW

更新日期：2006-07-01 00:00:00

abstract：:A histological diagnosis of pT4 stage is used as the basis for offering adjuvant therapy to patients with colorectal cancer. Histological features diagnostic of pT4 stage in colorectal cancer include: (1) presence of tumour perforation, (2) invasion of an adjacent organ, (3) direct or discontinuous tumour extending to...

journal_title：Journal of clinical pathology

authors： Swamy R

更新日期：2010-02-01 00:00:00

abstract：:A microcomputer system for use in the sequential processing of specimens has been developed in a hospital microbiology department which receives 90 000 specimens a year. Data handling is performed directly through the computers without the use of cards or worksheets. The system facilitates the multistep processing of ...

journal_title：Journal of clinical pathology

authors： Ashley R,Downing B

更新日期：1985-02-01 00:00:00

abstract：AIM:To investigate serum placental-type alkaline phosphatase (PLAP-type) activities in women with squamous and glandular malignancies of the reproductive tract using an immunoradiometric assay. METHODS:PLAP-type immunoreactivity was measured in 180 women with non-ovarian malignancies of the reproductive tract and the ...

journal_title：Journal of clinical pathology

authors： Ind TE,Iles RK,Carter PG,Lowe DG,Shepherd JH,Hudson CN,Chard T

更新日期：1994-11-01 00:00:00

abstract：:The cell volumes of mononuclear cells, T lymphocytes, B lymphocytes, and monocytes from the peripheral blood of 20 normal individuals were compared to neoplastic lymphoid cells from 14 patients with chronic lymphocytic leukaemia (CLL), 20 individuals with acute lymphocytic leukaemia (ALL), and 18 cases of non-Hodgkin'...

journal_title：Journal of clinical pathology

authors： Chapman EH,Kurec AS,Davey FR

更新日期：1981-10-01 00:00:00

abstract：:Serine esterases were detected in the granules of mucosal mast cells from rat, mouse, sheep, and man. Successful demonstration of enzyme activity required brief fixation (6 h) of tissues in 4% paraformaldehyde. Staining with naphthol AS-D chloroacetate produced an intense red reaction product in intraepithelial mucosa...

journal_title：Journal of clinical pathology

authors： Huntley JF,Newlands GF,Gibson S,Ferguson A,Miller HR

更新日期：1985-04-01 00:00:00

abstract：:Cancer lineage/tissue-of-origin assignment in cancers of unknown primary remains a challenge even when aided by massively parallel sequencing. The stakes are high for patients as many contemporary therapeutic strategies are disease-specific, and the biological differences can influence the patients' responses. Herein,...

journal_title：Journal of clinical pathology

authors： Yoon JY,Rosenbaum JN,Vergara N,Cohen RB,Wilson RB

更新日期：2020-08-27 00:00:00

abstract：AIMS:To determine whether the recommended methods for the handling of breast excision biopsy specimens from screening patients cause more laboratory work than those used for non-screening patients. METHODS:All breast excision biopsy specimens from 1990 were identified. Ninety one came from patients identified during t...

journal_title：Journal of clinical pathology

authors： Green B,McDicken IW,Turnbull LS

更新日期：1992-06-01 00:00:00

abstract：:A 65-year-old woman with a history of a left heminephrectomy for renal carcinoma developed hypercalcaemia 11 years after the operation. The same kidney was found to contain a recurrent renal carcinoma. After the radical nephrectomy of the left kidney, hypercalcaemia remitted but reappeared 11 months later. The right k...

journal_title：Journal of clinical pathology

authors： Szwed JJ,Gott LJ,Lempke RE,Seo IS

更新日期：1979-03-01 00:00:00

abstract：:The morphological classification and diagnosis of bladder neoplasms is summarised, with specific focus on histological typing, grading and staging. Four diagnostic categories are described on the basis of the pattern of growth of the urothelial lesions and tumours (flat, exophytic or papillary, endophytic, and invasiv...

journal_title：Journal of clinical pathology

authors： Montironi R,Mazzucchelli R,Scarpelli M,Lopez-Beltran A,Cheng L

更新日期：2008-01-01 00:00:00

abstract：AIMS:To establish the number of histological levels necessary for the evaluation of breast needle core biopsy (NCB) specimens taken from areas of mammographic calcification in patients presenting via the UK National Health Service Breast Screening Programme. METHODS:Retrospective review of a series of breast NCB speci...

journal_title：Journal of clinical pathology

authors： Kumaraswamy V,Carder PJ

更新日期：2007-06-01 00:00:00

abstract：:Circulating immune complexes have been detected in the sera of 24 Nigerian children with acute poststreptococcal glomerulonephritis using two methods. There was a significant correlation between levels of soluble complexes, detected in samples taken from patients in the oliguric phase of acute nephritis, and severity ...

journal_title：Journal of clinical pathology

authors： Onyewotu II,Mee J

更新日期：1978-09-01 00:00:00

abstract：AIMS:To evaluate the influence of involvement of the peritoneal surface by carcinoma of the rectum on local recurrence and prognosis. METHODS:Prospective analysis of pathological prognostic factors in 209 resections for rectal carcinoma between 1988 and 1993 with meticulous pathological technique particularly to asses...

journal_title：Journal of clinical pathology

authors： Shepherd NA,Baxter KJ,Love SB

更新日期：1995-09-01 00:00:00

abstract：INTRODUCTION:Whole slide images (WSI) have been used in many pathology applications such as teleconsultation, teaching and research, but not in primary diagnostics. The aim of this study was to test the feasibility of using WSI in primary diagnostics of paediatric pathology specimens and placental tissue. MATERIALS AN...

journal_title：Journal of clinical pathology

authors： Al-Janabi S,Huisman A,Nikkels PG,ten Kate FJ,van Diest PJ

更新日期：2013-03-01 00:00:00

abstract：:Sodium-alpha-naphthylamine-4-sulphonate (Naphthionin) appears to shorten the bleeding time in normal subjects and to be of value in the management of the bleeding defect in patients with thrombocytopenia when given by intravenous or intramuscular injection. A good response was achieved in three patients suffering from...

journal_title：Journal of clinical pathology

authors： POLLER L,MORE JR

更新日期：1964-11-01 00:00:00

abstract：:Sclerochoroidal calcification is an uncommon condition. Metabolic evaluation and clinical examination are important to exclude associated systemic conditions such as the Bartter and Gitelman syndromes. It has been suggested that the lesions seen in sclerochoroidal calcification are calcium pyrophosphate dihydrate crys...

journal_title：Journal of clinical pathology

authors： Gupta R,Hu V,Reynolds T,Harrison R

更新日期：2005-12-01 00:00:00