Cell volumes of normal and malignant mononuclear cells.

abstract：BACKGROUND:Kaposi's sarcoma is considered to be an angioproliferative disease associated with a novel herpesvirus (KSHV/HHV8), but the precise pathophysiology of the lesion remains unclear. The study of clonality in Kaposi's sarcoma using X linked DNA polymorphism has been difficult so far, because of a very strong pre...

journal_title：Journal of clinical pathology

authors： Delabesse E,Oksenhendler E,Lebbé C,Vérola O,Varet B,Turhan AG

更新日期：1997-08-01 00:00:00

abstract：:A 43-year-old man, admitted with a swollen right thigh, was diagnosed with a deep vein thrombosis. On day 6 he became septic. A CT scan demonstrated a right-sided hydronephrosis and a large retroperitoneal collection. Blood cultures and perinephric pus grew Escherichia coli resistant to amoxicillin only. On day 12 a v...

journal_title：Journal of clinical pathology

authors： Alleyne SA,Bukhari SS,Fraser M,Spiers P

更新日期：2010-04-01 00:00:00

abstract：:Toxoplasmosis is an infection, congenital or acquired, caused by Toxoplasma gondii. A pilot study using toxoplasmin skin antigen was undertaken to establish the incidence of the infection in the London area as a preliminary to a larger study of the effects of the infection upon pregnancy, the foetus, and the newborn i...

journal_title：Journal of clinical pathology

authors： Ruoss CF,Bourne GL

更新日期：1969-11-01 00:00:00

abstract：:Strokes are one of the most common causes of mortality and long term severe disability. There is evidence that lipoprotein (a) (Lp(a)) is a predictor of many forms of vascular disease, including premature coronary artery disease. Several studies have also evaluated the association between Lp(a) and ischaemic (thrombot...

journal_title：Journal of clinical pathology

authors： Milionis HJ,Winder AF,Mikhailidis DP

更新日期：2000-07-01 00:00:00

abstract：:Metabolic balance studies for iron have been carried out on 24 apparently healthy elderly people (11 men and 13 women) aged 69.7 to 85.5 years living in their own homes and eating self selected diets. Several biochemical and haematological indices of iron state were also measured. The mean daily iron intake was 176 mu...

journal_title：Journal of clinical pathology

authors： Bunker VW,Lawson MS,Clayton BE

更新日期：1984-12-01 00:00:00

abstract：:These guidelines update the previous UK HER2 testing guidelines and have been formulated to give advice on methodology, interpretation and quality assurance to ensure that HER2 testing results are accurate, reliable and timely with the expansion of testing to all patients with breast cancer at the time of primary diag...

journal_title：Journal of clinical pathology

authors： Walker RA,Bartlett JM,Dowsett M,Ellis IO,Hanby AM,Jasani B,Miller K,Pinder SE

更新日期：2008-07-01 00:00:00

abstract：:A case of recurrent intussusception in a 76 year old man associated with vascular proliferation is reported. The initial biopsy specimen showed that ulceration and inflammation were not features. The proliferation was so florid as to point to an angiomatous lesion. At this stage a diagnosis of intussusception was not ...

journal_title：Journal of clinical pathology

authors： Ramsden KL,Newman J,Moran A

更新日期：1993-01-01 00:00:00

abstract：:Acute myocardial disease, which may be associated with abnormal platelet activity, has been reported after routine immunisation. Thirty-two army apprentices undergoing immunisation were studied for changes in the heparin neutralising activity (HNA) of platelet poor plasma. HNA increased after immunisation. This increa...

journal_title：Journal of clinical pathology

authors： Baker IA,Howells CH,O'Brien JR

更新日期：1979-11-01 00:00:00

abstract：:Thirty two fire victims with smoke inhalation, with or without burns, and 26 control subjects had bronchoalveolar lavage performed. Cell yields and differential cell counts were assessed. All patients and controls were cigarette smokers. Patients with smoke inhalation (SI) injury generally showed higher total bronchoa...

journal_title：Journal of clinical pathology

authors： Riyami BM,Tree R,Kinsella J,Clark CJ,Reid WH,Campbell D,Gemmell CG

更新日期：1990-01-01 00:00:00

abstract：:Platelet adhesiveness has been assessed on whole blood from a series of 34 diabetics and 50 control subjects using adenosine diphosphate (A.D.P.) and by adherence to glass microspherules (ballotini). Using both techniques it was possible to demonstrate a significant increase in platelet adhesiveness in the diabetic pa...

journal_title：Journal of clinical pathology

authors： Shaw S,Pegrum GD,Wolff S,Ashton WL

更新日期：1967-11-01 00:00:00

abstract：:A cytochemical study of the lysosomal enzyme beta-glucuronidase in 60 cases of acute leukaemia has shown a qualitative difference in the cytoplasmic distribution of the enzyme between blast cells of the lymphoid and myeloid cell series. This difference provides a useful additional method for cytochemical classificatio...

journal_title：Journal of clinical pathology

authors： Mann JR,Simpson JS,Munkley RM,Stuart J

更新日期：1971-12-01 00:00:00

abstract：:Staphylococcus aureus isolated between 1967 and 1975 from the nose and skin lesions of patients in dermatology wards and from the burns of patients in a burns unit in Birmingham showed a high incidence of multiple antibiotic-resistant strains in both environments. Over 20% of the strains isolated from patients on admi...

journal_title：Journal of clinical pathology

authors： Ayliffe GA,Green W,Livingston R,Lowbury EJ

更新日期：1977-01-01 00:00:00

abstract：:Three adults with alpha 1-antitrypsin deficiency are described. In two of the cases the deficiency was genetically determined (cases 1 and 2), and each demonstrated unusual features of the disease. The liver in case 1 (homozygous) showed cholangiolar hyperplasia which has been recorded only once before. Case 2 (hetero...

journal_title：Journal of clinical pathology

authors： Sweeney EC

更新日期：1975-08-01 00:00:00

abstract：:The simultaneous estimation of steroids in plasma was carried out by the assay of cortisol, corticosterone, and testosterone. The method entails separation by means of thin layer chromatography, followed by conversion to a fluorophore and fluorimetric measurement. Its major advantages are its high specificity, its abi...

journal_title：Journal of clinical pathology

authors： Mattingly D,Martin H,Tyler C

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND:Prognostic factors in predicting outcomes in patients with head and neck squamous-cell carcinoma (HNSCC) are limited to the clinical-pathological parameters, including lymph node metastasis, location, grade and stage of the disease. AIM:To determine whether the expression of these proteins has a value in pr...

journal_title：Journal of clinical pathology

authors： Mhawech-Fauceglia P,Dulguerov P,Beck A,Bonet M,Allal AS

更新日期：2007-02-01 00:00:00

abstract：:Two cancer-associated proteins, carcinoembryonic antigen (CEA) and pregnancy-associated alpha2 glycoprotein (PAG), together with 13 normal serum proteins were measured in the serum and effusion fluid of patients with ascites and pleural effusions. The results indicate that CEA measurement in effusion fluid is more eff...

journal_title：Journal of clinical pathology

authors： Booth SN,Lakin G,Dykes PW,Burnett D,Bradwell AR

更新日期：1977-06-01 00:00:00

abstract：:A 45-year-old man is described in whom there is currently ERCP and histological evidence of primary sclerosing cholangitis (PSC). A liver biopsy obtained 29 years ago shows similar histological features confirming that he had PSC at that time. This case indicates that PSC may follow a relatively benign course. ...

journal_title：Journal of clinical pathology

authors： Goudie BM,Birnie GG,Watkinson G,MacSween RN

更新日期：1983-11-01 00:00:00

abstract：:Several diseases of the small intestine, including gluten-sensitivity, present with malabsorption and a "flat" mucosa. Determination of the mitotic index of epithelial lymphocytes provides a simple, objective method of assessing, and thus of predicting, whether a flat mucosa is due to gluten-sensitivity (index greater...

journal_title：Journal of clinical pathology

authors： Marsh MN,Haeney MR

更新日期：1983-02-01 00:00:00

abstract：:Operation specimens from 52 Hong Kong patients considered to have tuberculosis of the spine were sent at -78 degrees C to London where they were cultured on two Löwenstein-Jensen medium slopes, a slope of 7H11 medium made selective with antibiotics and in two bottles of selective liquid Kirchner medium. Cultures of M ...

journal_title：Journal of clinical pathology

authors： Allen BW,Mitchison DA,Darbyshire J,Chew WW,Gabriel M

更新日期：1983-06-01 00:00:00

abstract：:Using a radioimmunoassay technique serum alpha-fetoprotein could be detected in healthy adults in concentrations of less than 20 microgram/l. Of patients with acute, viral hepatitis 43% exhibited a transient rise of serum alpha-fetoprotein, the peak occurring eight to nine days after the maximum recorded serum asparta...

journal_title：Journal of clinical pathology

authors： Eleftheriou N,Heathcote J,Thomas HC,Sherlock S

更新日期：1977-08-01 00:00:00

abstract：AIMS:Sinusoidal dilatation and congestion (SDC) in liver biopsy may be obstructive (due to venous outflow impairment) or non-obstructive in nature. The significance of this finding in the post-liver transplant setting remains unexplored. METHODS:We herein retrospectively analysed all post-transplant liver biopsies sho...

journal_title：Journal of clinical pathology

authors： Bakshi N,Rastogi A,Pamecha V,Bihari C

更新日期：2020-08-24 00:00:00

abstract：:Although the UK National Institute for Health and Care Excellence guidelines recommend that in patients with biopsy-proven invasive lobular carcinoma (ILC), preoperative MRI scan is considered, the accuracy of diagnosis of ILC in core biopsy of the breast has not been previously investigated. Eleven pathology laborato...

journal_title：Journal of clinical pathology

authors： Naidoo K,Beardsley B,Carder PJ,Deb R,Fish D,Girling A,Hales S,Howe M,Wastall LM,Lane S,Lee AH,Philippidou M,Quinn C,Stephenson T,Pinder SE

更新日期：2016-12-01 00:00:00

abstract：AIM:To assess the reliability of local international normalised ratios (INR) using a set of three international reference preparation (IRP) certified freeze dried plasmas. METHODS:55 centres in the United Kingdom and the Republic of Ireland participated; 36 centres employed coagulometers and 19 a manual prothrombin ti...

journal_title：Journal of clinical pathology

authors： Poller L

更新日期：1998-05-01 00:00:00

abstract：:The necropsy findings in an elderly woman, who had been treated with methyldopa and who had died during treatment for accidental hypothermia, showed acute periductal inflammation of obviously similar duration in an entopic pancreas in the wall of the jejunum and in the ectopic pancreas. This supports the hypothesis th...

journal_title：Journal of clinical pathology

authors： Benbow EW

更新日期：1988-04-01 00:00:00

abstract：:Thirteen meningiomas of varying light microscopic features were studied immunohistologically using a panel of monoclonal antibodies directed against epithelial, mesenchymal, and neural components. All 13 meningiomas showed expression of epithelial membrane antigen, vimentin, and S100 protein, as did normal meninges. F...

journal_title：Journal of clinical pathology

authors： Theaker JM,Gatter KC,Esiri MM,Fleming KA

更新日期：1986-04-01 00:00:00

abstract：:With lymph node enlargement, the possibility of a malignant process such as metastatic carcinoma or lymphoma needs to be excluded. This report describes a 47 year old woman with inguinal lymph node enlargement initially suspicious for lymphoma. Fine needle aspiration findings favoured reactive hyperplasia, but a malig...

journal_title：Journal of clinical pathology

authors： Péoc'h M,Duprez D,Grice G,Fabre-Bocquentin B,Gressin R,Pasquier B

更新日期：2000-07-01 00:00:00

abstract：AIMS:Determine whether a simple prewash step will provide adequate amounts of high-quality DNA from core needle biopsies for molecular sequencing studies. METHODS:The quantitative and qualitative metrics of DNA recovered from core needle biopsies processed either by 1) formalin fixation and paraffin embedding (FFPE), ...

journal_title：Journal of clinical pathology

authors： Mojica WD,Hou T,Sykes D,Dey-Rao R

更新日期：2017-06-01 00:00:00

abstract：AIM:To evaluate the clinical usefulness of three commercially available assays for Her-2/neu oncogene and protein measurements. The Her-2/neu protein is overexpressed, mostly as a result of gene amplification, in 20-30% of human breast cancers, and has been shown to have prognostic and predictive value for treatment wi...

journal_title：Journal of clinical pathology

authors： Wang S,Saboorian MH,Frenkel E,Hynan L,Gokaslan ST,Ashfaq R

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:Helicobacter pylori related gastric intestinal metaplasia (IM) is considered to be a precancerous lesion. AIMS:To identify the effects of H pylori eradication on K-ras mutations, cell kinetics in IM and histological changes in patients with and without gastric cancers in a one-year prospective study. METHO...

journal_title：Journal of clinical pathology

authors： Watari J,Tanaka A,Tanabe H,Sato R,Moriichi K,Zaky A,Okamoto K,Maemoto A,Fujiya M,Ashida T,Das KM,Kohgo Y

更新日期：2007-08-01 00:00:00

abstract：:One hundred cases of transitional cell carcinoma of the bladder were studied to determine whether squamous metaplasia and other histological features within the bladder can be of value in predicting outcome of treatment with radiotherapy. Sixty cases showed the changes of squamous metaplasia, and of this group 46 (78%...

journal_title：Journal of clinical pathology

authors： Martin JE,Jenkins BJ,Zuk RJ,Blandy JP,Baithun SI

更新日期：1989-03-01 00:00:00