Sinusoidal dilatation and congestion in post-transplant liver biopsies from patients presenting with transaminitis.

abstract：AIM:To investigate serum placental-type alkaline phosphatase (PLAP-type) activities in women with squamous and glandular malignancies of the reproductive tract using an immunoradiometric assay. METHODS:PLAP-type immunoreactivity was measured in 180 women with non-ovarian malignancies of the reproductive tract and the ...

journal_title：Journal of clinical pathology

authors： Ind TE,Iles RK,Carter PG,Lowe DG,Shepherd JH,Hudson CN,Chard T

更新日期：1994-11-01 00:00:00

abstract：:The API 20 STREP system was used to identify 146 known strains from seven species of the genus Listeria, including both pathogenic and environmental strains. The gallery was easy to use and tests, with the exception of leucine arylamidase (LAP) and starch fermentation (AMD), were simple to interpret. Identification to...

journal_title：Journal of clinical pathology

authors： MacGowan AP,Marshall RJ,Reeves DS

更新日期：1989-05-01 00:00:00

abstract：:Attempts to detect hepatitis B antigen in faeces and bile should take into account the degradation and disappearance of the surface antigens in an environment containing proteolytic enzymes in the presence of bile salts as in the intestinal lumen. The cores of the Dane particles are much more stable than the surface a...

journal_title：Journal of clinical pathology

authors： Moodie JW,Stannard LM,Kipps A

更新日期：1974-09-01 00:00:00

abstract：:This paper urges the benefits of applying more widely a method for pathology laboratory costing originally devised for a clinical chemistry department, and illustrates these with examples drawn from costing studies in three clinical laboratories. Heads of pathology departments, laboratory managers, administrators and ...

journal_title：Journal of clinical pathology

authors： Broughton PM,Woodford FP

更新日期：1983-09-01 00:00:00

abstract：AIMS:To assess the clinical efficacy of diagnostic procedures for breast cancer at a teaching hospital using internal auditing tools and quality control measures. METHODS:A retrospective assessment of 500 patients who underwent core needle biopsy (wide-bore needle biopsy; WBN) of palpable or non-palpable breast nodes ...

journal_title：Journal of clinical pathology

authors： Verenhitach BD,Elias S,Patrocínio AC,Nazário AC,Waizberg A

更新日期：2011-10-01 00:00:00

abstract：:Temporal changes in gastric antibody response were investigated in 113 (51 men, 62 women) patients with confirmed pernicious anaemia. Their ages ranged from 31-92 years (mean (SD 13.2) 66). At diagnosis, parietal cell antibody and intrinsic factor antibody were detected in 90.9% and 39.1% of all patients, respectively...

journal_title：Journal of clinical pathology

authors： Davidson RJ,Atrah HI,Sewell HF

更新日期：1989-10-01 00:00:00

abstract：:Electron microscopical and cytochemical studies of intestinal biopsies from a patient with typical features of the Cronkhite-Canada syndrome show that the primary process affects the crypts. This results in cystic dilatation associated with expansion and focal degeneration of the crypt compartment of the intestinal ep...

journal_title：Journal of clinical pathology

authors： Jenkins D,Stephenson PM,Scott BB

更新日期：1985-03-01 00:00:00

abstract：AIMS:The localisation of the translocation breakpoint of the Ewing sarcoma family of tumours shows significant variability on relatively large regions of fusion partner genes. As a consequence, many alternative forms of EWSR1-ETS translocation exist which make the RNA-based molecular diagnostics of Ewing sarcoma family...

journal_title：Journal of clinical pathology

authors： Patócs B,Németh K,Garami M,Arató G,Kovalszky I,Szendroi M,Fekete G

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Hodgkin's lymphoma (HL) is characterised by an ineffective immune response that is predominantly mediated by CD4+ T-cells. AIMS:To analyse the expression of the key regulatory T-cell transcription factors (TFs) in the T-cells of HL involved tissues in order to assess the nature of the T(H) immune response i...

journal_title：Journal of clinical pathology

authors： Atayar C,van den Berg A,Blokzijl T,Boot M,Gascoyne RD,Visser L,Poppema S

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:Peutz-Jeghers syndrome (PJS) is an autosomal dominant hamartomatous polyposis syndrome of the gastrointestinal tract, caused by a germline STK11/LKB1 mutation. Nasal polyposis was described in the original report by Peutz. Recently, a molecular-genetic association between nasal polyposis and PJS has been rep...

journal_title：Journal of clinical pathology

authors： de Leng WW,Westerman AM,Weterman MA,Jansen M,van Dekken H,Giardiello FM,de Rooij FW,Paul Wilson JH,Offerhaus GJ,Keller JJ

更新日期：2007-04-01 00:00:00

abstract：AIMS:To assess the prevalence of gastric giardiasis in patients undergoing upper gastrointestinal endoscopy, and to define the clinicopathological correlates of gastric Giardia lamblia infection. METHODS:Consecutive gastric biopsy specimens (n = 15,023) from 11,085 patients, taken at Feltre City Hospital (north easter...

journal_title：Journal of clinical pathology

authors： Doglioni C,De Boni M,Cielo R,Laurino L,Pelosio P,Braidotti P,Viale G

更新日期：1992-11-01 00:00:00

abstract：:The pathological diagnoses and classification schemes for thyroid carcinoma have changed over the past 20 years and continue to do so. New entities have been described and molecular analyses have suggested better characterisation and grouping of certain tumours. Because some of the lesions have been named differently ...

journal_title：Journal of clinical pathology

authors： Baloch Z,LiVolsi VA,Tondon R

更新日期：2013-09-01 00:00:00

abstract：:Platelet adhesiveness has been measured in citrated whole blood and in platelet-rich plasma obtained from normal subjects, splenectomized patients, and from patients in whom the diagnosis of recurrent venous thrombosis had been made. The duration of centrifugation used in the preparation of platelet-rich plasma was fo...

journal_title：Journal of clinical pathology

authors： McBride JA

更新日期：1968-05-01 00:00:00

abstract：AIMS:To study whether differences in eradication rates of antibiotics may be explained by differences in secretion of antibiotics in gastric juice. METHODS:A single intravenous dose of either ampicillin 500 mg, erythromycin 500 mg, or metronidazole 500 mg was administered to four healthy Helicobacter pylori negative v...

journal_title：Journal of clinical pathology

authors： van Zanten SJ,Goldie J,Hollingsworth J,Silletti C,Richardson H,Hunt RH

更新日期：1992-03-01 00:00:00

abstract：:Sera can produce nuclear or perinuclear immunofluorescence staining in neutrophils which may be caused by antibodies with differing antigenic specificities. These include perinuclear antineutrophil cytoplasmic antibodies (P-ANCA), granulocyte specific antinuclear antibody (GS-ANA), and antinuclear antibody (ANA). Ther...

journal_title：Journal of clinical pathology

authors： Chowdhury SM,Broomhead V,Spickett GP,Wilkinson R

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:Helicobacter pylori related gastric intestinal metaplasia (IM) is considered to be a precancerous lesion. AIMS:To identify the effects of H pylori eradication on K-ras mutations, cell kinetics in IM and histological changes in patients with and without gastric cancers in a one-year prospective study. METHO...

journal_title：Journal of clinical pathology

authors： Watari J,Tanaka A,Tanabe H,Sato R,Moriichi K,Zaky A,Okamoto K,Maemoto A,Fujiya M,Ashida T,Das KM,Kohgo Y

更新日期：2007-08-01 00:00:00

abstract：:Partial myoepithelial differentiation is common in simple epithelial hyperplasia (epitheliosis) of the breast but functional myoepithelial differentiation with basement membrane production is exceedingly rare. A peculiar change of hyaline globules within benign epithelial hyperplasia has been recognised before as "col...

journal_title：Journal of clinical pathology

authors： Wells CA,Wells CW,Yeomans P,Viña M,Jordan S,d'Ardenne AJ

更新日期：1990-11-01 00:00:00

abstract：:Mast cells were identified by electronmicroscopy in the alveolar wall of the lung in 20 subjects (10 normal, 10 abnormal). A quantitative and qualitative study was made of the mast cells. In the normal lung there was an average concentration of 350 mast cells/mm2 of alveolar wall and in the abnormal 523/mm2. Mast cell...

journal_title：Journal of clinical pathology

authors： Fox B,Bull TB,Guz A

更新日期：1981-12-01 00:00:00

abstract：:An enzyme linked immunosorbent assay (ELISA) to measure free serum IgG antibodies to Pseudomonas aeruginosa in patients with cystic fibrosis was developed. Seven strains of P aeruginosa cells, treated with glutaraldehyde and representing the most commonly isolated serotypes in our cystic fibrosis unit, were used. The ...

journal_title：Journal of clinical pathology

authors： Brett MM,Ghoneim AT,Littlewood JM,Losowsky MS

更新日期：1986-10-01 00:00:00

abstract：:Human papillomavirus (HPV) infection of cervical intraepithelial neoplasia (CIN) and invasive cervical carcinoma was investigated using in situ DNA-DNA hybridisation on histological sections of formalin fixed, paraffin embedded tissue to assess the technique's sensitivity and to assess retrospectively the association ...

journal_title：Journal of clinical pathology

authors： Collins JE,Jenkins D,McCance DJ

更新日期：1988-03-01 00:00:00

abstract：AIM:To evaluate the accuracy of the approximate linear formula of International Normalised Ratio (INR) imprecision by formal mathematical analysis. METHODS:Using probability theory, an exact formula for the coefficient of variation (CV) of the INR was derived. The CV from the approximate formula was compared with the ...

journal_title：Journal of clinical pathology

authors： Bennett ST,Critchfield GC

更新日期：1994-07-01 00:00:00

abstract：:A polyclonal antiserum, produced in sheep and reactive against purified human leucocyte elastase, has been applied to paraffin sections from a range of human tissues by means of the indirect immunoperoxidase method. Striking and consistent results have been obtained. Normal or inflammatory granulocytes were intensely ...

journal_title：Journal of clinical pathology

authors： Crocker J,Jenkins R,Burnett D

更新日期：1984-10-01 00:00:00

abstract：:Zygomycosis is not often diagnosed in the United Kingdom, and so the possible importance of the findings in a patient with disseminated zygomycosis who had been treated with chemotherapy for erythroleukaemia was not appreciated until histological examination of specimens obtained at necropsy provided a presumptive dia...

journal_title：Journal of clinical pathology

authors： Benbow EW,Delamore IW,Stoddart RW,Reid H

更新日期：1985-09-01 00:00:00

abstract：:Cervical biopsies from 97 women with malignant cells in cervical scrape smears have been studied. Forty-eight patients had invasive squamous carcinoma, and 49 had intraepithelial lesions. Of these, six had dedifferentiated carcinoma in situ, nine had the differentiated lesions generally known as ;severe dysplasia', an...

journal_title：Journal of clinical pathology

authors： Grubb C,Janota I

更新日期：1967-01-01 00:00:00

abstract：AIMS:EGFR tyrosine kinase inhibitors (TKIs) are first-line molecularly targeted therapies in patients with advanced non-small cell lung cancer (NSCLC) who carry sensitising EGFR mutations, due to its superior survival outcomes compared with conventional chemotherapy regimens. In this study, we sought to identify clinic...

journal_title：Journal of clinical pathology

authors： Ng IK,Kumarakulasinghe NB,Syn NL,Soo RA

更新日期：2021-02-01 00:00:00

abstract：:Cell surface proteolysis is an important mechanism for generating biologically active proteins that mediate a range of cellular functions and contribute to biological processes such as angiogenesis. Although most studies have focused on the plasminogen system and matrix metalloproteinases (MMPs), recently there has be...

journal_title：Journal of clinical pathology

authors： Noel A,Maillard C,Rocks N,Jost M,Chabottaux V,Sounni NE,Maquoi E,Cataldo D,Foidart JM

更新日期：2004-06-01 00:00:00

abstract：AIMS:To determine the value of squamous mucosal histology in the assessment of patients with gastro-oesophageal reflux symptoms. METHODS:Sixty six patients with reflux symptoms underwent endoscopy with oesophageal biopsy, manometry, and 24 hour oesophageal pH testing. The following histological features were assessed ...

journal_title：Journal of clinical pathology

authors： Bowrey DJ,Williams GT,Clark GW

更新日期：2003-03-01 00:00:00

abstract：:A technique, using indirect immunoperoxidase antibody (IPA), was developed for the detection of IgG antibody to Chlamydia trachomatis. The IPA technique employs glass slides with air-dried and acetone-fixed C trachomatis infected cells, which can be stored at -70 degrees C and used for several months. Antibody titres ...

journal_title：Journal of clinical pathology

authors： Cevenini R,Rumpianesi F,Donati M,Sarov I

更新日期：1983-03-01 00:00:00

abstract：:Synovium was collected from 15 patients who were undergoing joint surgery. Two groups were defined by clinical diagnosis: patients with primary osteoarthritis (n = 4); and those with rheumatoid arthritis (n = 11). The synovium was studied using histological and morphometric techniques. In agreement with previous studi...

journal_title：Journal of clinical pathology

authors： Kennedy TD,Plater-Zyberk C,Partridge TA,Woodrow DF,Maini RN

更新日期：1988-08-01 00:00:00

abstract：:An enzyme linked immunoadsorbent assay (ELISA) was used to detect IgG, IgM, and IgA antibody in urine to a crude antigenic mixture prepared from six arbitrarily chosen strains of common coliform urinary pathogens. In a group of patients with symptoms of urinary tract infection 24 of 80 (30%) urine samples were positiv...

journal_title：Journal of clinical pathology

authors： McKenzie H,Young DN

更新日期：1987-07-01 00:00:00