Determination of individual bile acids in biological fluids by thin-layer chromatography and fluorimetry.

abstract：AIMS:To determine the value of squamous mucosal histology in the assessment of patients with gastro-oesophageal reflux symptoms. METHODS:Sixty six patients with reflux symptoms underwent endoscopy with oesophageal biopsy, manometry, and 24 hour oesophageal pH testing. The following histological features were assessed ...

journal_title：Journal of clinical pathology

authors： Bowrey DJ,Williams GT,Clark GW

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND/AIMS:To evaluate the need for routine histopathological analysis of enucleated/eviscerated eyes and changes in indications for eye removal. METHODS:Retrospective review of all enucleation/evisceration histopathology reports over 20 years. Clinical history was correlated with pathological findings. Two 10 ye...

journal_title：Journal of clinical pathology

authors： Saeed MU,Chang BY,Khandwala M,Shivane AG,Chakrabarty A

更新日期：2006-02-01 00:00:00

abstract：AIMS:To isolate RNA and DNA simultaneously from formalin fixed paraffin wax embedded tissue to assess the clonality of enteropathy associated T cell lymphomas and to analyse it in detail by a non-radioactive method of T cell receptor complementarity determining region 3 (CDR3) spectratyping. METHODS:DNA and RNA were i...

journal_title：Journal of clinical pathology

authors： O'Shea U,Wyatt JI,Howdle PD

更新日期：1997-10-01 00:00:00

abstract：AIMS:Myospherulosis is a rare condition characterised by sac-like structures containing spheroid bodies in cysts or cystic spaces in the tissue. This condition has not previously been reported in the liver. The association with previous portal vein embolisation using a mixture of butyl 2-cyanoacrylate and ethiodised oi...

journal_title：Journal of clinical pathology

authors： Lui PC,Luk IS,Lee CK,Lui YH,Leung CY,Choi CH

更新日期：2004-02-01 00:00:00

abstract：AIMS:To study whether differences in eradication rates of antibiotics may be explained by differences in secretion of antibiotics in gastric juice. METHODS:A single intravenous dose of either ampicillin 500 mg, erythromycin 500 mg, or metronidazole 500 mg was administered to four healthy Helicobacter pylori negative v...

journal_title：Journal of clinical pathology

authors： van Zanten SJ,Goldie J,Hollingsworth J,Silletti C,Richardson H,Hunt RH

更新日期：1992-03-01 00:00:00

abstract：:The distribution of laminin, a basement membrane glycoprotein, was studied by an immunohistochemical technique in six samples of benign sclerosing lesions of extrahepatic bile ducts and in 11 sclerosing cholangiocarcinomas. The expression of laminin showed that benign glandular structures were surrounded by a mainly i...

journal_title：Journal of clinical pathology

authors： Haglund C,Roberts PJ,Nordling S

更新日期：1989-09-01 00:00:00

abstract：:Colonising Campylobacter pyloridis were identified histologically in gastric biopsy specimens from 89% of 83 patients with non-ulcer dyspepsia and chronic gastritis, but not in 58 dyspeptic patients with normal mucosa. The presence and population density of organisms was associated with the presence of intraepithelial...

journal_title：Journal of clinical pathology

authors： Wyatt JI,Rathbone BJ,Heatley RV

更新日期：1986-08-01 00:00:00

abstract：:During 1971 and 1972, 71 cultures of neisseriae that attacked lactose were received by this laboratory. All strains except one from an eye swab were from the nasopharynx of healthy subjects. Nineteen similar strains from the nasopharynx were isolated in this laboratory. The characteristics of these strains were compar...

journal_title：Journal of clinical pathology

authors： Pykett AH

更新日期：1973-06-01 00:00:00

abstract：:Thirteen unrelated patients with idiopathic haemochromatosis (eight men, five women) were studied. The diagnosis was based on clinical, biological, and histochemical findings. HLA typing was performed in all 13 and in all of their available first degree relatives (n = 31). HLA A3 was present in nine of 13 probands (69...

journal_title：Journal of clinical pathology

authors： Czìnk E,Gyódi EK,Német K,Hollán S

更新日期：1991-01-01 00:00:00

abstract：:A slight modification in tissue processing and staining technique enables a previously described method for staining aluminium to be used to demonstrate aluminium in osteomalacia associated with haemodialysis. The stain appears to be accurate in diagnosing this condition and may assist in establishing the diagnosis be...

journal_title：Journal of clinical pathology

authors： Buchanan MR,Ihle BU,Dunn CM

更新日期：1981-12-01 00:00:00

abstract：AIMS:To investigate proliferative activity in leukaemic and lymphomatous bone marrow infiltrates and to assess the feasibility of transport of specimens among institutions. METHODS:Proliferative activity in bone marrow trephine cryosections from 99 patients with non-Hodgkin's lymphoma (NHL), 23 patients with acute mye...

journal_title：Journal of clinical pathology

authors： White DM,Smith AG,Smith JL

更新日期：1994-03-01 00:00:00

abstract：:Early epidemiological studies of cervical neoplasia suggested a causal relation with sexual activity and human papillomaviruses (HPVs) have emerged as prime suspects as venerally transmitted carcinogens. HPVs fall into two broad camps: low risk types, associated with cervical condylomas and CIN 1; and high risk types ...

journal_title：Journal of clinical pathology

authors： Arends MJ,Buckley CH,Wells M

更新日期：1998-02-01 00:00:00

abstract：:Three adults with alpha 1-antitrypsin deficiency are described. In two of the cases the deficiency was genetically determined (cases 1 and 2), and each demonstrated unusual features of the disease. The liver in case 1 (homozygous) showed cholangiolar hyperplasia which has been recorded only once before. Case 2 (hetero...

journal_title：Journal of clinical pathology

authors： Sweeney EC

更新日期：1975-08-01 00:00:00

abstract：AIMS:To describe characteristics of a series of people accidentally and deliberately killed by air powered weapons. METHODS:Five cases of fatal airgun injury were identified by forensic pathologists and histopathologists. The circumstances surrounding the case, radiological examination, and pathological findings are d...

journal_title：Journal of clinical pathology

authors： Milroy CM,Clark JC,Carter N,Rutty G,Rooney N

更新日期：1998-07-01 00:00:00

abstract：:This review of the histomorphometry of bone outlines methods of biopsy and processing of specimens in the laboratory, the basic principles of morphometry, and the measurements made in order to obtain estimates of the proportional volumes and surfaces occupied by different components of bone. Variability such as that b...

journal_title：Journal of clinical pathology

authors： Revell PA

更新日期：1983-12-01 00:00:00

abstract：:Methods are described for the estimation of plasma and urine alpha-amino nitrogen by the colorimetric ninhydrin reaction; in the method for urine, both ammonia and urea are separated by a rapid ion-exchange resin procedure. Two methods of estimation are given; one has the advantage of great simplicity, but involves th...

journal_title：Journal of clinical pathology

authors： MATTHEWS DM,MUIR GG,BARON DN

更新日期：1964-03-01 00:00:00

abstract：:The hepatic and splenic storage iron, including the relative distribution between ferritin and haemosiderin, was estimated in 130 necropsies including normal accident cases and cases with a variety of diseases. The storage iron was also examined histochemically. It was found that in the normal subjects, on the average...

journal_title：Journal of clinical pathology

authors： Morgan EH,Walters MN

更新日期：1963-03-01 00:00:00

abstract：:A histological diagnosis of pT4 stage is used as the basis for offering adjuvant therapy to patients with colorectal cancer. Histological features diagnostic of pT4 stage in colorectal cancer include: (1) presence of tumour perforation, (2) invasion of an adjacent organ, (3) direct or discontinuous tumour extending to...

journal_title：Journal of clinical pathology

authors： Swamy R

更新日期：2010-02-01 00:00:00

abstract：:Sera can produce nuclear or perinuclear immunofluorescence staining in neutrophils which may be caused by antibodies with differing antigenic specificities. These include perinuclear antineutrophil cytoplasmic antibodies (P-ANCA), granulocyte specific antinuclear antibody (GS-ANA), and antinuclear antibody (ANA). Ther...

journal_title：Journal of clinical pathology

authors： Chowdhury SM,Broomhead V,Spickett GP,Wilkinson R

更新日期：1999-06-01 00:00:00

abstract：:This review surveys the staging systems used for the classification of colorectal carcinomas, including the TNM system, and focuses on the assessment of the nodal stage of the disease. It reviews the quantitative requirements for a regional metastatic work up, and some qualitative features of lymph nodes that may help...

journal_title：Journal of clinical pathology

authors： Cserni G

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:A previous survey has highlighted the fact that most individuals in chemical pathology identifiable from specialist society membership failed to publish material in Medline cited journals during a five year period. It could be considered that published research that is not cited in other work is not useful u...

journal_title：Journal of clinical pathology

authors： Reynolds TM,Wierzbicki AS

更新日期：2004-04-01 00:00:00

abstract：:A time and temperature relationship required to destroy certain pathogenic organisms in milk feeds has been ascertained. A method of achieving this destruction by using steam at atmospheric pressure is described, and a routine method for use in milk kitchens is suggested. ...

journal_title：Journal of clinical pathology

authors： Hughes KE,Darmady EM,Drewett SE

更新日期：1966-07-01 00:00:00

abstract：OBJECTIVE:We explore factors such as the blood sampling site (capillary vs venous), the equipment (HemoCue vs automated haematology analyser) and the model of the HemoCue device (201+ vs 301) that may impact haemoglobin measurements in capillary and venous blood. METHODS:Eleven studies were identified, and bias, conco...

journal_title：Journal of clinical pathology

authors： Rappaport AI,Karakochuk CD,Hess SY,Whitehead RD Jr,Namaste SML,Dary O,Parker ME,Neufeld LM,Larson LM,Newton S,Wegmuller R,Moorthy D

更新日期：2020-10-06 00:00:00

abstract：:The fetal antigen i has been demonstrated by indirect immunofluorescence on cord erythrocytes and placental trophoblast. A patient with disseminated choriocarcinoma developed high-tire anti-i cold agglutinins, and minor elevation of anti-i titres was seen in four out of six further patients with treated choriocarcinom...

journal_title：Journal of clinical pathology

authors： Boughton BJ

更新日期：1979-06-01 00:00:00

abstract：AIM:To evaluate the use of multimedia enhancements, using a computerised microscope, in the training of microscope skills. METHODS:The HOME microscope provides facilities to highlight features of interest in conjunction with either text display or aural presentation. A pilot study was carried out with 10 individuals, ...

journal_title：Journal of clinical pathology

authors： Gray E,Duvall E,Sprey J,Bird CC

更新日期：1998-04-01 00:00:00

abstract：AIM:To determine whether the pattern of involvement of the gastric mucosa in lymphocytic gastritis is predictive of the presence or absence of duodenal pathology. METHODS:50 cases (M:F, 26:24; median age 57 years) diagnosed as lymphocytic gastritis between 1986 and 1998 with concurrent duodenal (D2) biopsies were iden...

journal_title：Journal of clinical pathology

authors： Hayat M,Arora DS,Wyatt JI,O'Mahony S,Dixon MF

更新日期：1999-11-01 00:00:00

abstract：:Antibiotic discs from Oxoid, Mast, AB Biodisk, Difco, and Baltimore Biological Laboratories were compared, where discs of similar antibiotic content were available, in diffusion-sensitivity tests against organisms of known sensitivity. Discs from Oxoid and Mast gave zones 1-5 mm larger than discs from other manufactur...

journal_title：Journal of clinical pathology

authors： Brown DF,Kothari D

更新日期：1975-10-01 00:00:00

abstract：AIMS:Diffuse large B-cell lymphoma (DLBCL) is an aggressive and potentially fatal disease. Prediction of risk of relapse is based on clinical markers. There is a need for more accurate biomarkers to select patients for more aggressive first-line treatments. Peroxiredoxins (Prxs) are a family of potent antioxidant prote...

journal_title：Journal of clinical pathology

authors： Kuusisto ME,Haapasaari KM,Turpeenniemi-Hujanen T,Jantunen E,Soini Y,Peroja P,Bloigu R,Karihtala P,Kuittinen O

更新日期：2015-07-01 00:00:00

abstract：:Performance of CHROMagar Acinetobacter was assessed for the selective isolation and identification of Acinetobacter baumannii. The medium was effective in suppressing the growth of other Gram-positive and Gram-negative species while the addition of KPC supplement ensured growth of only carbapenem resistant A baumannii...

journal_title：Journal of clinical pathology

authors： Wareham DW,Gordon NC

更新日期：2011-02-01 00:00:00

abstract：:Zygomycosis is not often diagnosed in the United Kingdom, and so the possible importance of the findings in a patient with disseminated zygomycosis who had been treated with chemotherapy for erythroleukaemia was not appreciated until histological examination of specimens obtained at necropsy provided a presumptive dia...

journal_title：Journal of clinical pathology

authors： Benbow EW,Delamore IW,Stoddart RW,Reid H

更新日期：1985-09-01 00:00:00