ESTIMATION OF ALPHA-AMINO NITROGEN IN PLASMA AND URINE BY THE COLORIMETRIC NINHYDRIN REACTION.

abstract：:DNA typing was requested to investigate a presumptive cancer diagnosis error by confirming whether benign and cancerous prostatic tissue in the same presurgical haematoxylin and eosin stained slide belonged to the same person. After independent histological re-examination of the slide by a pathologist, manual slide di...

journal_title：Journal of clinical pathology

authors： Alonso A,Alves C,Suárez-Mier MP,Albarrán C,Pereira L,Fernández de Simón L,Martín P,García O,Gusmão L,Sancho M,Amorim A

更新日期：2005-01-01 00:00:00

abstract：:Lung tissue from 13 cases of unexplained non-immunological hydrops fetalis was examined by in situ hybridisation to detect parvovirus. Four specimens contained parvovirus DNA in cells in the blood vessel lumina and alveoli. Twenty six control cases were negative for parvovirus DNA. As there was no known epidemic of pa...

journal_title：Journal of clinical pathology

authors： Porter HJ,Khong TY,Evans MF,Chan VT,Fleming KA

更新日期：1988-04-01 00:00:00

abstract：:The aggregating effects of adenosine diphosphate, thrombin, 5-hydroxytryptamine, tryptamine, adrenaline and noradrenaline, and tri-ethyl tin have been carefully compared. The first three compounds in some circumstances produce remarkably similar effects although there are important differences. The kinetics of aggrega...

journal_title：Journal of clinical pathology

authors： O'BRIEN JR

更新日期：1964-05-01 00:00:00

abstract：:Autoinfective strongyloidiasis is often fatal in immunosuppressed patients or in immunocomprised hosts. An interesting case of Strongyloides stercolaris hyperinfection was seen in an immunocompetent patient. This report describes a case of fatal strogyloidiasis in a 79 year old man, who had suffered gastrointestinal d...

journal_title：Journal of clinical pathology

authors： Mayayo E,Gomez-Aracil V,Azua-Blanco J,Azua-Romeo J,Capilla J,Mayayo R

更新日期：2005-04-01 00:00:00

abstract：AIMS:To establish whether abnormalities in the course of the vertebral artery occur and whether they are relevant to arterial injury associated with head and neck movements. METHODS:Twenty vertebral arteries were carefully dissected at necropsy and abnormalities in course were noted, along with any other bony or carti...

journal_title：Journal of clinical pathology

authors： Johnson CP,Scraggs M,How T,Burns J

更新日期：1995-07-01 00:00:00

abstract：AIMS:To investigate the problems involved in undertaking immunohistochemistry (IHC) and nuclear morphometry using Bouin's fixed prostate biopsies. METHODS:Archival Bouin's fixed and formalin fixed, paraffin wax embedded prostatic biopsies were immunostained for three nuclear biomarkers (minichromosome maintenance prot...

journal_title：Journal of clinical pathology

authors： Ananthanarayanan V,Pins MR,Meyer RE,Gann PH

更新日期：2005-03-01 00:00:00

abstract：AIMS:To investigate the expression of catenins (alpha, beta, and gamma) in non-small cell lung carcinoma (NSCLC) and its relation to clinicopathological factors and prognosis. METHODS:The expression of catenins was analysed immunohistochemically in 261 patients with resected NSCLC, diagnosed between 1978 and 1996 in e...

journal_title：Journal of clinical pathology

authors： Pirinen RT,Hirvikoski P,Johansson RT,Hollmén S,Kosma VM

更新日期：2001-05-01 00:00:00

abstract：:Cell surface proteolysis is an important mechanism for generating biologically active proteins that mediate a range of cellular functions and contribute to biological processes such as angiogenesis. Although most studies have focused on the plasminogen system and matrix metalloproteinases (MMPs), recently there has be...

journal_title：Journal of clinical pathology

authors： Noel A,Maillard C,Rocks N,Jost M,Chabottaux V,Sounni NE,Maquoi E,Cataldo D,Foidart JM

更新日期：2004-06-01 00:00:00

abstract：:Cytological diagnosis in a series of 153 skin lesions is presented. The diagnosis in each case has been compared with the clinical assessment and, where available, the biopsy result (85 lesions). Of 131 basal cell carcinomas, a cytological diagnosis was possible in 124 while biopsyl failed to identify two of the 73 le...

journal_title：Journal of clinical pathology

authors： Brown CL,Klaber MR,Robertson MG

更新日期：1979-04-01 00:00:00

abstract：:Thirteen meningiomas of varying light microscopic features were studied immunohistologically using a panel of monoclonal antibodies directed against epithelial, mesenchymal, and neural components. All 13 meningiomas showed expression of epithelial membrane antigen, vimentin, and S100 protein, as did normal meninges. F...

journal_title：Journal of clinical pathology

authors： Theaker JM,Gatter KC,Esiri MM,Fleming KA

更新日期：1986-04-01 00:00:00

abstract：:A Cyto-Tek staining machine designed for Papanicolau staining of cervical smears has been adapted for auramine staining of smears of sputum and other clinical specimens for acid-fast bacilli. The results compared favourably with those obtained by a manual method of staining. Contamination of negative smears by acid-fa...

journal_title：Journal of clinical pathology

authors： Heimer GV,Joseph N,Taylor CE

更新日期：1978-02-01 00:00:00

abstract：AIM:To assess the ability of the commercially available monoclonal antibody 1B12 (BioGenex, San Ramon, USA) to identify C albicans in formalin fixed, paraffin wax embedded material (FFPE). METHODS:Broth cultures of 20 strains of seven Candida species were resuspended in 4% agarose blocks, fixed in formalin for 24 hour...

journal_title：Journal of clinical pathology

authors： Williams DW,Jones HS,Allison RT,Potts AJ,Lewis MA

更新日期：1998-11-01 00:00:00

abstract：:Three cases of fungal endocarditis are described, each following a homograft valve replacement for aortic stenosis. The causative organism was C. albicans. The characteristic findings included soft, easily detached vegetations consisting of fungal colonies, aneurysms, embolization of large vessels, and lack of respons...

journal_title：Journal of clinical pathology

authors： McConnell EM,Roberts C

更新日期：1967-07-01 00:00:00

abstract：AIM:The rapid and fully automated Idylla EGFR Mutation Assay has been specifically designed to process formalin-fixed, paraffin-embedded sections without requiring preliminary DNA extraction. This study evaluates whether this approach can also process archival smears from patients with non-small cell lung cancer (NSCLC...

journal_title：Journal of clinical pathology

authors： De Luca C,Conticelli F,Leone A,Gragnano G,Salatiello M,Galasso P,Pisapia P,Grillo LR,Iaccarino A,Vigliar E,Bellevicine C,Malapelle U,Troncone G

更新日期：2019-09-01 00:00:00

abstract：:Small cell neuroendocrine carcinoma of the breast is a rare tumour with less than 30 cases reported in the literature. The clinicopathological findings of three cases of primary neuroendocrine carcinoma of the breast and a review of the pertinent literature are presented. The morphological and immunohistochemical patt...

journal_title：Journal of clinical pathology

authors： Adegbola T,Connolly CE,Mortimer G

更新日期：2005-07-01 00:00:00

abstract：AIMS:To report the clinicopathological characteristics of patients with ocular adnexal marginal zone B cell lymphoma (MZBL) with IgG4-positive plasma cells. METHODS:114 biopsy samples of ocular adnexal MZBLs were analysed. MZBLs with IgG4-positive plasma cells were included when the IgG4:IgG ratio was >40% (IgG4-relat...

journal_title：Journal of clinical pathology

authors： Kubota T,Moritani S,Yoshino T,Nagai H,Terasaki H

更新日期：2010-12-01 00:00:00

abstract：AIMS:To compare the efficacy of and tolerance to oral fluconazole and intraconazole in preventing fungal infection in neutropenic patients with haematological malignancies. PATIENTS:213 consecutive, afebrile adult patients treated with or without autologous stem cell transplantation for haematological malignancies. M...

journal_title：Journal of clinical pathology

authors： Huijgens PC,Simoons-Smit AM,van Loenen AC,Prooy E,van Tinteren H,Ossenkoppele GJ,Jonkhoff AR

更新日期：1999-05-01 00:00:00

abstract：:Forty six lymph nodes were examined with the indirect immunoperoxidase technique for the distribution of fibronectin and laminin. Fibronectin was present in the framework of the tissue and the basal lamina of blood vessels, giving a clear outline of nodal architecture. Intracellular fibronectin was observed in cases o...

journal_title：Journal of clinical pathology

authors： Reilly JT,Nash JR,Mackie MJ,McVerry BA

更新日期：1985-08-01 00:00:00

abstract：:Human papillomavirus (HPV) infection of cervical intraepithelial neoplasia (CIN) and invasive cervical carcinoma was investigated using in situ DNA-DNA hybridisation on histological sections of formalin fixed, paraffin embedded tissue to assess the technique's sensitivity and to assess retrospectively the association ...

journal_title：Journal of clinical pathology

authors： Collins JE,Jenkins D,McCance DJ

更新日期：1988-03-01 00:00:00

abstract：:An enzyme linked immunosorbent assay (ELISA) based on the antibody class capture method for the detection of specific IgM against Toxoplasma gondii, using the microtitre plate format, was developed. Antigen binding was detected using a monoclonal antibody, CIE3, conjugated to horseradish peroxidase. Prior mixing of th...

journal_title：Journal of clinical pathology

authors： Payne RA,Joynson DH,Balfour AH,Harford JP,Fleck DG,Mythen M,Saunders RJ

更新日期：1987-03-01 00:00:00

abstract：:Serum and tissue hepatitis B virus (HBV) markers were compared in 35 alcoholic and 23 non-alcoholic subjects affected by chronic liver disease. Seventeen point one per cent of alcoholic and 21.7% of non-alcoholic subjects had HBV tissue markers, but not serum markers, for this virus. It is therefore concluded that sho...

journal_title：Journal of clinical pathology

authors： Cuccurullo L,Rambaldi M,Iaquinto G,Ferraraccio F,Ambrosone L,Giardullo N,De Vita A

更新日期：1987-02-01 00:00:00

abstract：:The discovery of ETS gene fusions as common events in prostate cancer represents a paradigmatic shift in the significance attributed to chromosomal translocations as a key mechanistic player in carcinogenesis. However, these chromosomal fusion events are poorly understood, as their functional significance and therapeu...

journal_title：Journal of clinical pathology

authors： Attard G,Ang JE,Olmos D,de Bono JS

更新日期：2008-08-01 00:00:00

abstract：AIM:To determine the frequency of skip lesions in an unselected series of temporal artery biopsies and compare the results with other series. METHODS:The study was a retrospective review of 102 consecutive temporal artery biopsies taken in a five year period (1992-1997) in one large hospital. RESULTS:35 cases (34.3%)...

journal_title：Journal of clinical pathology

authors： Poller DN,van Wyk Q,Jeffrey MJ

更新日期：2000-02-01 00:00:00

abstract：:Purulent exudate from 28 cases of Bartholin's abscess were examined for aerobic, anaerobic, and microaerophilic bacteria. Three cases gave no bacterial growth, five cases grew facultative bacteria only, and a further three grew a mixture of facultative and anaerobic bacteria. One case gave a pure growth of a microaero...

journal_title：Journal of clinical pathology

authors： Wren MW

更新日期：1977-11-01 00:00:00

abstract：BACKGROUND:Laboratories traditionally culture toxoplasma tachyzoites in animals for testing and experimental use. This article considers why available cell culture methods are not used more often. AIM:To compare HeLa cell culture and animal culture for production of toxoplasma tachyzoites. METHODS:In 2000 HeLa cultur...

journal_title：Journal of clinical pathology

authors： Chatterton JM,McDonagh S,Ho-Yen DO

更新日期：2010-05-01 00:00:00

abstract：:In cases of adult T cell leukaemia neoplastic T cell infiltration in the skin was accompanied by an increase in Langerhans cells. This is in keeping with the view that Langerhans cells may induce antigen-specific and allogenic T cell activation. ...

journal_title：Journal of clinical pathology

authors： Shamoto M

更新日期：1983-03-01 00:00:00

abstract：AIMS:Ki-67 is a prognostic marker in breast cancer; however, the use of the Ki-67 labelling index (LI) in clinical practice requires a consistent and easily accessible scoring method. The present study evaluated the use of the free internet-based image analysis program ImmunoRatio to score Ki-67 LI in breast cancer in ...

journal_title：Journal of clinical pathology

authors： Yeo MK,Kim HE,Kim SH,Chae BJ,Song BJ,Lee A

更新日期：2017-08-01 00:00:00

abstract：:Pre-mRNA splicing is an essential process in eukaryotic cells where the transcribed intronic sequences are removed, prior to translation into protein. PRPF31 is a ubiquitously expressed splicing factor, which aids in the assembly of the macromolecular spliceosome. Mutations in PRPF31 cause autosomal dominant retinitis...

journal_title：Journal of clinical pathology

authors： Rose AM,Luo R,Radia UK,Bhattacharya SS

更新日期：2017-09-01 00:00:00

abstract：:Antibodies against the group polysaccharide of group A streptococci were estimated by means of a haemagglutination reaction. In this reaction human erythrocytes of blood group O were sensitized with polysaccharide esterified with myristoylchloride. The optimal conditions of the reactions were determined by varying the...

journal_title：Journal of clinical pathology

authors： Goedvok-de Groot LE,Michel-Bensink N,van Es-Boon MM,van Vonno AH,Michel MF

更新日期：1974-11-01 00:00:00

abstract：:Experiments were performed to evaluate five commercial kit assays used for the detection of antibodies to dsDNA. The kits were compared using a performance index score as recommended by the guidelines of the European Committee for Clinical Laboratory Standards. The highest performance score was obtained using the radi...

journal_title：Journal of clinical pathology

authors： McMillan SA,Fay AC

更新日期：1988-11-01 00:00:00