Update on eighth edition American Joint Committee on Cancer classification for cutaneous melanoma and overview of potential pitfalls in histological examination of staging parameters.


:Cutaneous melanoma causes most of the skin cancer deaths in the USA. Melanoma is the fifth most common cancer among men and the sixth most common cancer among women. The incidence of melanoma has risen sharply over the past three decades. In this review, which is informed by our extensive experience at a large cancer centre, we outline the key differences between the tumour, node and metastases staging criteria for cutaneous melanoma in the seventh and eighth editions of the AJCC Cancer Staging Manual We also offer advice on how to assess the histophenotypic parameters that are relevant for staging, with a special focus on avoiding potential pitfalls, and how to report all the prognostically and therapeutically relevant histophenotypic parameters. Correct assessment and reporting of these clinically relevant histophenotypic parameters is of outmost importance for practising pathologists because these parameters help treating clinicians select the most appropriate personalised treatment for patients in this era of promising targeted and immunotherapies.


J Clin Pathol


Trinidad CM,Torres-Cabala CA,Curry JL,Prieto VG,Aung PP




Has Abstract


2019-04-01 00:00:00














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    journal_title:Journal of clinical pathology

    pub_type: 杂志文章


    authors: Kuroiwa K,Uchino H,Yokomizo A,Naito S

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  • Cancer genes mutation profiling in calcifying epithelial odontogenic tumour.

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    journal_title:Journal of clinical pathology

    pub_type: 杂志文章


    authors: de Sousa SF,Diniz MG,França JA,Fontes Pereira TDS,Moreira RG,Santos JND,Gomez RS,Gomes CC

    更新日期:2018-03-01 00:00:00

  • A simple biological method for detecting streptococcal nicotinamide adenine dinucleotide glycohydrolase.

    abstract::A biological method for detecting streptococcal nicotinamide adenine dinucleotide glycohydrolase (NADG) is presented, based on its ability to inhibit the growth of Haemophilus parainfluenzae. Three hundred clinical isolates of beta-haemolytic streptococci were tested. All isolates producing NADG belonged to Lancefield...

    journal_title:Journal of clinical pathology

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    journal_title:Journal of clinical pathology

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    pub_type: 杂志文章,多中心研究


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    pub_type: 杂志文章


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    journal_title:Journal of clinical pathology

    pub_type: 杂志文章


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    journal_title:Journal of clinical pathology

    pub_type: 杂志文章


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    journal_title:Journal of clinical pathology

    pub_type: 杂志文章


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    pub_type: 杂志文章


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    journal_title:Journal of clinical pathology

    pub_type: 杂志文章,评审


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    journal_title:Journal of clinical pathology

    pub_type: 杂志文章


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    journal_title:Journal of clinical pathology

    pub_type: 杂志文章


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    更新日期:1994-03-01 00:00:00

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    journal_title:Journal of clinical pathology

    pub_type: 杂志文章



    更新日期:1962-03-01 00:00:00

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    journal_title:Journal of clinical pathology

    pub_type: 杂志文章


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    abstract::Three strains of Past. septica were isolated in Hong Kong. The clinical histories and the detailed bacteriological and serological studies are presented. ...

    journal_title:Journal of clinical pathology

    pub_type: 杂志文章


    authors: WONG PC,CHAN-TEOH CH

    更新日期:1964-03-01 00:00:00

  • Biochemical classification of Klebsiella correlated with the severity of the associated disease.

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    journal_title:Journal of clinical pathology

    pub_type: 杂志文章


    authors: FOSTER WD,BRAGG J

    更新日期:1962-09-01 00:00:00

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    journal_title:Journal of clinical pathology

    pub_type: 杂志文章


    authors: Jones DM

    更新日期:1967-07-01 00:00:00

  • A quality assurance exercise to evaluate the accuracy and reproducibility of chromogenic in situ hybridisation for HER2 analysis in breast cancer.

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    journal_title:Journal of clinical pathology

    pub_type: 杂志文章,多中心研究


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    更新日期:2008-06-01 00:00:00