Lymphoid tissue and lymphoid-glandular complexes of the colon: relation to diverticulosis.

abstract：AIMS:Our laboratory is a centralised centre receiving routine non-small cell lung cancer (NSCLC) samples for programmed death ligand-1 (PD-L1) immunohistochemical (IHC) evaluation. Since literature data are not concordant here we review our clinical records to assess the rate of PD-L1 positive and negative NSCLC cases ...

journal_title：Journal of clinical pathology

authors： Vigliar E,Malapelle U,Iaccarino A,Acanfora G,Pisapia P,Clery E,De Luca C,Bellevicine C,Troncone G

更新日期：2019-06-01 00:00:00

abstract：:Although epithelial mucin has been demonstrated in ordinary mammary duct carcinomas, it is formed profusely in the uncommon mucous carcinomas. A histochemical study of mucous carcinomas of the breast and colon showed that both types produce similar mucins, viz, acid and neutral, although the mammary carcinomas produce...

journal_title：Journal of clinical pathology

authors： Cooper DJ

更新日期：1974-04-01 00:00:00

abstract：:Hereditary spherocytosis is a relatively common haematological disorder and will be encountered by all haematologists. The abundance of new information, dealing principally with molecular and genetic aspects of pathophysiology, is beginning to have implications for its investigation and management. While these advance...

journal_title：Journal of clinical pathology

authors： Smedley JC,Bellingham AJ

更新日期：1991-06-01 00:00:00

abstract：:A case is described in which marked hepatic fibrosis probably resulted from the prolonged treatment of acute leukaemia with methotrexate. ...

journal_title：Journal of clinical pathology

authors： Talerman A,Thompson RB

更新日期：1966-01-01 00:00:00

abstract：:Platelet transfusions have the highest incidence of post-transfusion sepsis compared with any other blood products. Recent reports suggest that platelet-related bacteraemia occurs at a frequency of approximately 50 times greater than that for red blood cells. The source is usually skin contaminants from the donor and ...

journal_title：Journal of clinical pathology

authors： Coutinho H,Galloway A,Ajdukiewicz K,Cleeve V

更新日期：2010-03-01 00:00:00

abstract：:Eighty-four children with acute lymphoblastic leukaemia (ALL) who had relapsed in bone marrow were studied to assess whether treatment would be more successful if relapse was detected before the disease became clinically evident. Patients whose relapse was detected by routine bone marrow examination before the disease...

journal_title：Journal of clinical pathology

authors： Haworth C,Heppleston AD,Morris Jones PH,Campbell RH,Evans DI,Palmer MK

更新日期：1981-05-01 00:00:00

abstract：BACKGROUND:The prognosis of adenoid cystic carcinoma (ACC), a malignant salivary gland tumour, depends on clinicopathological parameters. To decipher the biological behaviour of ACC, and to identify patients at risk of developing metastases, additional markers are needed. METHODS:Expression of the cell cycle proteins ...

journal_title：Journal of clinical pathology

authors： Vékony H,Raaphorst FM,Otte AP,van Lohuizen M,Leemans CR,van der Waal I,Bloemena E

更新日期：2008-06-01 00:00:00

abstract：AIMS:To ascertain the effect of enhanced surveillance following an outbreak of waterborne cryptosporidiosis on the number of faecal specimens submitted to the local microbiology laboratory and the number positive for common enteric pathogens. The outbreak provided an opportunity to estimate the extent of routine under ...

journal_title：Journal of clinical pathology

authors： Qamruddin AO,Keaney MG,McCann R,Chadwick PR

更新日期：2002-04-01 00:00:00

abstract：:Michaëlsson's (1961) method for the measurement of plasma bilirubin concentration was found to be complicated by conjugated bilirubin. Delaying the addition of the accelerator, diphylline, corrected this fault. The method was calibrated using serum or plasma, since reconstituted protein solutions introduced large erro...

journal_title：Journal of clinical pathology

authors： Thompson RP

更新日期：1969-07-01 00:00:00

abstract：:In a twenty-year period 19 appendicectomy specimens were diagnosed as primary Crohn's disease. This represents 4.9% of the total number of both resection specimens and mucosal biopsies diagnosed as Crohn's disease during that time. This is a review of the main histopathological features found in these appendices and t...

journal_title：Journal of clinical pathology

authors： Allen DC,Biggart JD

更新日期：1983-06-01 00:00:00

abstract：:Visceral botryomycosis is rare, and documented sites are lung, brain, kidney, liver and prostate. This report describes a rare autopsy case of disseminated visceral botryomycosis, with bulky, grape-like botryomycotic vegetations in the heart, and similar abscesses in the lungs and bone marrow. This is the first such r...

journal_title：Journal of clinical pathology

authors： Gupta K,Das A,Radotra BD,Bhalla A

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Hodgkin's lymphoma (HL) is characterised by an ineffective immune response that is predominantly mediated by CD4+ T-cells. AIMS:To analyse the expression of the key regulatory T-cell transcription factors (TFs) in the T-cells of HL involved tissues in order to assess the nature of the T(H) immune response i...

journal_title：Journal of clinical pathology

authors： Atayar C,van den Berg A,Blokzijl T,Boot M,Gascoyne RD,Visser L,Poppema S

更新日期：2007-10-01 00:00:00

abstract：:A "Centrifichem" centrifugal analyser was found using a double fluorescence/bacterial tracer method to be a source of airborne and surface contamination in the laboratory. The airborne contamination was controlled by a modification incorporating a filter. Ubiquitous surface contamination generally accompanied the proc...

journal_title：Journal of clinical pathology

authors： Kennedy DA,Stevens JF,Horn AN

更新日期：1988-11-01 00:00:00

abstract：:The degree of inflammation in the trachea, bronchi, and lungs of 139 cot deaths has been analysed and each case allocated to one of four groups. In group I the changes were considered to be serious enough to have caused death, while group II cases showed similar abnormalities but of a less severe nature, and in this g...

journal_title：Journal of clinical pathology

authors： Tapp E,Jones DM,Tobin JO

更新日期：1975-11-01 00:00:00

abstract：:An antibody was raised against a protein isolated from the cytoplasm of mesothelioma cells. It was subsequently used in an immunoperoxidase procedure on formalin fixed, paraffin embedded tissue sections. A representative sample of benign and malignant tumours from all the systems of the human body was examined. All th...

journal_title：Journal of clinical pathology

authors： Donna A,Betta PG,Bellingeri D,Marchesini A

更新日期：1986-09-01 00:00:00

abstract：AIMS:Epidermal growth factor receptor (EGFR) T790M mutations can be detected in the circulating tumour DNA from plasma of patients with non-small cell lung cancer (NSCLC) to triage patients for osimertinib eligibility and monitor patients longitudinally for development of T790M-mediated resistance. METHODS:Using dropl...

journal_title：Journal of clinical pathology

authors： Spence T,Perera S,Weiss J,Grenier S,Ranich L,Shepherd F,Stockley TL

更新日期：2021-02-01 00:00:00

abstract：BACKGROUND:Breast-conserving surgery currently focuses on improving margin clearance and excision volume, the main pathology report parameters for oncological and cosmetic outcomes. AIM:To quantitatively evaluate discrepancies in surgical and pathological estimates of breast specimen sizes, including the influence of ...

journal_title：Journal of clinical pathology

authors： Krekel NM,van Slooten HJ,Barbé E,de Lange de Klerk ES,Meijer S,van den Tol MP

更新日期：2012-03-01 00:00:00

abstract：AIM:To examine lymphocyte subsets in patients with myelodysplastic syndromes (MDS); and to correlate immunohistological variables with prognosis. METHODS:Bone marrow trephine biopsy specimens from 65 patients with MDS were immunophenotyped using a panel of antibodies. A minimum of 1000 cells from representative areas ...

journal_title：Journal of clinical pathology

authors： Hilbe W,Eisterer W,Schmid C,Starz I,Silly H,Duba C,Ludescher C,Thaler J

更新日期：1994-06-01 00:00:00

abstract：AIMS:To determine whether Ki-67 immunoexpression in penile squamous cell carcinoma (PSCC) has a prognostic value and correlates with lymph node metastasis, human papillomavirus (HPV) infection and patient survival. METHODS:148 formalin-fixed paraffin-embedded PSCC samples were tissue-microarrayed, including 97 usual-t...

journal_title：Journal of clinical pathology

authors： Stankiewicz E,Ng M,Cuzick J,Mesher D,Watkin N,Lam W,Corbishley C,Berney DM

更新日期：2012-06-01 00:00:00

abstract：:A case of acute myelomonocytic leukaemia (AMMOL) is reported in which skin infiltration with xanthomatous nodules was the presenting feature. The histological, including ultrastructural, appearances are described. ...

journal_title：Journal of clinical pathology

authors： O'Donnell JR,Tansey P,Chung P,Burnett AK,Thomson J,McDonald GA

更新日期：1982-11-01 00:00:00

abstract：:A spectrophotometric assay of proteolytic enzyme activity is described in which the optical density obtained by a given enzyme preparation is related (2 alpha less than 0.01) to the serological activity of that preparation in a two stage technique. The assay appears to be of use for the standardisation of enzyme prepa...

journal_title：Journal of clinical pathology

authors： Phillips PK,Prior D,Dawes B

更新日期：1984-03-01 00:00:00

abstract：:Purulent exudate from 28 cases of Bartholin's abscess were examined for aerobic, anaerobic, and microaerophilic bacteria. Three cases gave no bacterial growth, five cases grew facultative bacteria only, and a further three grew a mixture of facultative and anaerobic bacteria. One case gave a pure growth of a microaero...

journal_title：Journal of clinical pathology

authors： Wren MW

更新日期：1977-11-01 00:00:00

abstract：AIMS:Inflammatory bowel disease (IBD)-associated precancerous lesions may be adenomatous or non-adenomatous with various histomorphologies. We aim to validate the newly proposed classification, to explore the neoplastic nature of the non-adenomatous lesions and to elucidate the molecular mechanisms underlying the diffe...

journal_title：Journal of clinical pathology

authors： Gui X,Köbel M,Ferraz JG,Iacucci M,Ghosh S,Liu S,Ou Y,Perizzolo M,Winkfein RJ,Rambau P,Demetrick DJ

更新日期：2020-07-01 00:00:00

abstract：:Late-stage ovarian carcinoma is almost universally fatal. BRCA mutations are associated with an improved outcome and enhanced sensitivity to platinum chemotherapy, yet recurrence and platinum resistance remain a major problem and highly effective regimens following platinum failure do not yet exist. Here we report a r...

journal_title：Journal of clinical pathology

authors： Osher DJ,Kushner YB,Arseneau J,Foulkes WD

更新日期：2011-10-01 00:00:00

abstract：:Serine esterases were detected in the granules of mucosal mast cells from rat, mouse, sheep, and man. Successful demonstration of enzyme activity required brief fixation (6 h) of tissues in 4% paraformaldehyde. Staining with naphthol AS-D chloroacetate produced an intense red reaction product in intraepithelial mucosa...

journal_title：Journal of clinical pathology

authors： Huntley JF,Newlands GF,Gibson S,Ferguson A,Miller HR

更新日期：1985-04-01 00:00:00

abstract：AIMS:To investigate the immunohistochemical expression of p53 protein in non-Hodgkin's lymphomas (NHL) and its relation to that of c-myc p62 oncoprotein and proliferating cell nuclear antigen (PCNA). METHODS:Paraffin wax embedded tissue from 90 non-Hodgkin's lymphomas (72 B cell and 18 T cell) was stained immunohistoc...

journal_title：Journal of clinical pathology

authors： Korkolopoulou P,Oates J,Kittas C,Crocker J

更新日期：1994-01-01 00:00:00

abstract：:Care in the preparation and preservation of reagents, together with certain modifications in apparatus and technique, have eliminated the difficulties from plasma ammonia analysis. Ammonia contamination from the laboratory atmosphere has not proved an especial hazard, and no major setback has been encountered in the a...

journal_title：Journal of clinical pathology

authors： Fenton JC,Williams AH

更新日期：1968-01-01 00:00:00

abstract：AIMS:To establish a mechanism to examine the components of turnaround time in a representative cross-section of laboratory users; and to identify potential areas for improvement. METHODS:Information was collected manually from result reports received by eight laboratory users: three wards in the main hospital, four GP...

journal_title：Journal of clinical pathology

authors： Smellie WS,Johnston J,Galloway PJ

更新日期：1994-07-01 00:00:00

abstract：:Eight strains of Pseudomonas putrefaciens have been received from among 466 strains of Pseudomonas submitted to the Computer Trials Laboratory for identification over the last eight years. Two of the strains of P. putrefaciens from patients with otitis media and otitis externa respectively appear to have played a path...

journal_title：Journal of clinical pathology

authors： Holmes B,Lapage SP,Malnick H

更新日期：1975-02-01 00:00:00

abstract：:An ultramicro electrophoretic technique for the separation of serum lipoproteins is described using agarose gel on microscope slides.The interaction between the agarose gel and lipoproteins has been reduced and the separation between beta- and pre-beta-lipoproteins has been improved over existing methods. A semiquanti...

journal_title：Journal of clinical pathology

authors： Elphick MC

更新日期：1971-02-01 00:00:00