Newborn screening for sickle cell disease in the Republic of Benin.

abstract：:In this necropsy review of 37 cases of acute pancreatitis, evidence is presented that there are at least two different initiating mechanisms in acute necrotising pancreatitis in man. Firstly, there is primary duct inflammation, with subsequent inflammation and necrosis of the pancreatic parenchyma surrounding the excr...

journal_title：Journal of clinical pathology

authors： Foulis AK

更新日期：1980-12-01 00:00:00

abstract：AIM:To establish whether infection with Epstein-Barr virus (EBV) contributed to the development of coronary artery lesions in a six year old child with an aneurysm and stenoses of the coronary arteries and suspected Kawasaki disease. METHODS:Postmortem paraffin wax sections of the coronary artery and myocardium were e...

journal_title：Journal of clinical pathology

authors： Culora GA,Moore IE

更新日期：1997-02-01 00:00:00

abstract：:It has been suggested that Coxsackie B virus infections may play a part in causing or triggering myocardial infarction. This study was designed to compare the incidence of such infections in Coronary Care Unit patients and normal controls. The choice of a suitable criterion for diagnosis of Coxsackie infection is disc...

journal_title：Journal of clinical pathology

authors： O'Neill D,McArthur JD,Kennedy JA,Clements G

更新日期：1983-06-01 00:00:00

abstract：AIM:To examine peripheral blood and skeletal muscle from patients with chronic fatigue syndrome for exogenous retrovirus. METHODS:Blood samples from 30 patients and muscle biopsy specimens of 15 patients were examined for retroviral sequences by DNA extraction, polymerase chain reaction (PCR), and Southern blotting hy...

journal_title：Journal of clinical pathology

authors： Gow JW,Simpson K,Schliephake A,Behan WM,Morrison LJ,Cavanagh H,Rethwilm A,Behan PO

更新日期：1992-12-01 00:00:00

abstract：AIMS:To examine whether variations in pathology test requesting between different general practices can be accounted for by sociodemographic or other descriptive indicators of the practice. METHOD:This was a comparative analysis of requesting patterns across a range of pathology tests representing 95% of those request...

journal_title：Journal of clinical pathology

authors： Smellie WS,Galloway MJ,Chinn D,Gedling P

更新日期：2002-04-01 00:00:00

abstract：:The rate of digestion of fibrin was measured in vitro by an isotopic technique in 140 blood samples of differing fibrinogen concentration; the assessment of fibrinolytic activity thus obtained was compared with a standard method of measurement, the dilute whole blood lysis time. The lysis time was related exponentiall...

journal_title：Journal of clinical pathology

authors： Hickman JA,Gordon-Smith IC,Whitfield PF,Godfrey SJ

更新日期：1973-03-01 00:00:00

abstract：:A moderatley sensitive, rapid, and economical test scheme for the detection of infantile gastroenteritis virus (IGV) in stool or antibody in serum has been developed and evaluated. The test scheme with minor modifications was an adaptation of a counter-immunoelectro-osmophoresis system we once used for the detection o...

journal_title：Journal of clinical pathology

authors： Middleton PJ,Petric M,Hewitt CM,Szymanski MT,Tam JS

更新日期：1976-03-01 00:00:00

abstract：:IgD myeloma is a rare disorder with a very poor prognosis. An unusual case is reported where prolonged remission was obtained. Immunohistochemical staining of the bone marrow trephine biopsy specimen proved invaluable in documenting early relapse. It is suggested that immunohistochemistry should be adopted more widely...

journal_title：Journal of clinical pathology

authors： Kettle P,Morris TC

更新日期：1994-08-01 00:00:00

abstract：AIMS:We aimed to study epidermal growth factor receptor (EGFR) expression in surgically resected pancreatic ductal adenocarcinomas (PDACs) by immunohistochemistry and their relationship to clinicopathological features, cell proliferation and cell adhesion protein expression. METHODS:A total of 99 PDACs were analysed o...

journal_title：Journal of clinical pathology

authors： Handra-Luca A,Hammel P,Sauvanet A,Lesty C,Ruszniewski P,Couvelard A

更新日期：2014-04-01 00:00:00

abstract：AIM:To examine lymphocyte subsets in patients with myelodysplastic syndromes (MDS); and to correlate immunohistological variables with prognosis. METHODS:Bone marrow trephine biopsy specimens from 65 patients with MDS were immunophenotyped using a panel of antibodies. A minimum of 1000 cells from representative areas ...

journal_title：Journal of clinical pathology

authors： Hilbe W,Eisterer W,Schmid C,Starz I,Silly H,Duba C,Ludescher C,Thaler J

更新日期：1994-06-01 00:00:00

abstract：:Taking a kidney biopsy is not a trivial procedure. The sample is almost invariably smaller than the pathologist would like. Investigation usually requires division into even smaller samples to permit the application of specialist techniques. In some cases the biopsy is taken not for diagnosis, but to assess the extent...

journal_title：Journal of clinical pathology

authors： Furness PN

更新日期：2000-06-01 00:00:00

abstract：AIMS:To evaluate an indirect immunofluorescence flow cytometry technique in a series of patients with large fetomaternal haemorrhage (FMH). METHODS:Patient samples identified by Kleihauer testing in local laboratories as having FMH > 4 ml were sent for flow cytometric analysis. In a proportion of cases the mothers rec...

journal_title：Journal of clinical pathology

authors： Johnson PR,Tait RC,Austin EB,Shwe KH,Lee D

更新日期：1995-11-01 00:00:00

abstract：:Review of published work and analysis of clinical data and pathology of four biopsy specimens from two patients with laryngeal contact granuloma showed that its peptic origin was derived from a gastro-oesophago-laryngeal reflux. It is proposed that the term "peptic granuloma" should be given to this phenomenon. This t...

journal_title：Journal of clinical pathology

authors： Miko TL

更新日期：1989-08-01 00:00:00

abstract：:An automated method for the microbiological assay of vitamin B(12) is described. A chloramphenicol-resistant strain of Lactobacillus leichmannii is used as the test organism and this eliminates the need for sterilization or aseptic addition. Precipitation of the serum protein is avoided by dilution of the serum with a...

journal_title：Journal of clinical pathology

authors： Davis RE,Moulton J,Kelly A

更新日期：1973-07-01 00:00:00

abstract：AIMS:To analyse the entity specific incidence and disease specific survival (DSS) of non-Hodgkin lymphomas (NHLs) in Tyrol/Austria, 1991-2000. METHODS:Data from 1307 NHLs (excluding primary cutaneous lymphomas and monoclonal gammopathies of undetermined significance) were obtained. Current status was available for all...

journal_title：Journal of clinical pathology

authors： Mitterlechner T,Fiegl M,Mühlböck H,Oberaigner W,Dirnhofer S,Tzankov A

更新日期：2006-01-01 00:00:00

abstract：:The costs of a clinical chemistry laboratory in a district general hospital were studied. The system used has certain advantages over the conventional Cooper Lybrand method. The time taken by technicians to perform tests was more variable than expected and the cost of sample collection was higher than process-cost for...

journal_title：Journal of clinical pathology

authors： Stilwell JA

更新日期：1981-06-01 00:00:00

abstract：AIMS:Sinusoidal dilatation and congestion (SDC) in liver biopsy may be obstructive (due to venous outflow impairment) or non-obstructive in nature. The significance of this finding in the post-liver transplant setting remains unexplored. METHODS:We herein retrospectively analysed all post-transplant liver biopsies sho...

journal_title：Journal of clinical pathology

authors： Bakshi N,Rastogi A,Pamecha V,Bihari C

更新日期：2020-08-24 00:00:00

abstract：:A radial immunodiffusion technique has been used to measure levels of four serum proteins in preeclampsia with or without proteinuria and in normal pregnant and non-pregnant controls. In preeclampsia unaccompanied by proteinuria, albumin and transferrin levels are similar to those found in the normal pregnant controls...

journal_title：Journal of clinical pathology

authors： Horne CH,Howie PW,Goudie RB

更新日期：1970-09-01 00:00:00

abstract：BACKGROUND:Laboratories traditionally culture toxoplasma tachyzoites in animals for testing and experimental use. This article considers why available cell culture methods are not used more often. AIM:To compare HeLa cell culture and animal culture for production of toxoplasma tachyzoites. METHODS:In 2000 HeLa cultur...

journal_title：Journal of clinical pathology

authors： Chatterton JM,McDonagh S,Ho-Yen DO

更新日期：2010-05-01 00:00:00

abstract：:Formalin fixation followed by routine paraffin embedding allows the demonstration of intracellular immunoglobulin by a sandwich technique using either peroxidase or fluorescein isothyocyanate labelled antibody conjugates. The results compared favourably with those obtained using either the fresh frozen or the Sainte-M...

journal_title：Journal of clinical pathology

authors： Burns J,Hambridge M,Taylor CR

更新日期：1974-07-01 00:00:00

abstract：:In all cases of primary endocardial fibroelastosis investigated diffuse degenerative changes in the ganglion cells were detected. Thickened endocardium was formed by the proliferation of mesenchymal cells located under the endothelial endocardium and of the mesenchyme surrounding the necrobiotic muscle cells. In some ...

journal_title：Journal of clinical pathology

authors： Zóltowska A

更新日期：1971-04-01 00:00:00

abstract：AIMS:To investigate the histopathological features of the synovial lining of the knee following implantation of an artificial cruciate ligament. METHODS:Eighty two patients underwent anterior cruciate ligament reconstruction for chronic, symptomatic instability of the knee. The cruciate ligament was reconstructed with...

journal_title：Journal of clinical pathology

authors： Barry M,Thomas SM,Rees A,Shafighian B,Mowbray MA

更新日期：1995-06-01 00:00:00

abstract：:A case of extramedullary myeloblastic transformation of chronic myeloid leukaemia is reported. This was characterised by an unusual clinical and haematological course and showed a unique cytogenetic pattern. ...

journal_title：Journal of clinical pathology

authors： Flanagan NG,Harrison CJ,Harry DS,Ridway JC

更新日期：1985-07-01 00:00:00

abstract：:A cytochemical study of the lysosomal enzyme beta-glucuronidase in 60 cases of acute leukaemia has shown a qualitative difference in the cytoplasmic distribution of the enzyme between blast cells of the lymphoid and myeloid cell series. This difference provides a useful additional method for cytochemical classificatio...

journal_title：Journal of clinical pathology

authors： Mann JR,Simpson JS,Munkley RM,Stuart J

更新日期：1971-12-01 00:00:00

abstract：AIMS:In the gastric antrum and body, foveolar hyperplasia is a feature of reactive gastritis resulting from--for example, duodenogastric bile reflux and the use of non-steroidal anti-inflammatory drugs (NSAIDs). The aim of this study was to examine the occurrence and clinical relevance of gastric cardiac foveolar hyper...

journal_title：Journal of clinical pathology

authors： Voutilainen M,Juhola M,Färkkilä M,Sipponen P

更新日期：2002-05-01 00:00:00

abstract：:Cervical smears were reviewed from 62 women who developed squamous carcinoma of the cervix up to 18 years later. The findings indicate that the prevention of cervical cancer by screening depends very largely on the detection of severe dyskaryosis. In this series there was no evidence that mild dyskaryosis was a foreru...

journal_title：Journal of clinical pathology

authors： Robertson JH,Woodend B,Elliott H

更新日期：1994-03-01 00:00:00

abstract：:Eight strains of Pseudomonas putrefaciens have been received from among 466 strains of Pseudomonas submitted to the Computer Trials Laboratory for identification over the last eight years. Two of the strains of P. putrefaciens from patients with otitis media and otitis externa respectively appear to have played a path...

journal_title：Journal of clinical pathology

authors： Holmes B,Lapage SP,Malnick H

更新日期：1975-02-01 00:00:00

abstract：:A young woman presented with bilateral ovarian tumours. Multiple sections of each tumour were shown to many pathologists for consultation; some considered the tumours to be borderline, whereas others thought that one or both of them was malignant. Morphometry showed that the numerical classification probabilities for ...

journal_title：Journal of clinical pathology

authors： Baak JP,Van der Ley G

更新日期：1984-10-01 00:00:00

abstract：:Hereditary breast cancer accounts for up to 5-10% of all breast carcinomas. Recent studies have demonstrated that mutations in two high-penetrance genes, namely BRCA1 and BRCA2, are responsible for about 16% of the familial risk of breast cancer. Even though subsequent studies have failed to find another high-penetran...

journal_title：Journal of clinical pathology

authors： Tan DS,Marchiò C,Reis-Filho JS

更新日期：2008-10-01 00:00:00

abstract：:As patients with multiple myeloma (MM) have a variable clinical course, predictive markers would help determine the appropriate treatment strategy. Clinical staging is commonly used to predict outcome, but tumour marker expression and the underlying genetic changes are increasingly used to assess the biological aggres...

journal_title：Journal of clinical pathology

authors： Yeung J,Chang H

更新日期：2008-07-01 00:00:00