Search for retrovirus in the chronic fatigue syndrome.

abstract：AIM:To compare the histological characteristics of Helicobacter pylori positive chronic gastritis in patients with and without associated duodenitis. METHODS:Gastric mucosal biopsy specimens were obtained from patients undergoing endoscopy for dyspepsia. Severity of gastritis and density of H pylori infection were gra...

journal_title：Journal of clinical pathology

authors： Phull PS,Price AB,Stephens J,Rathbone BJ,Jacyna MR

更新日期：1996-05-01 00:00:00

abstract：:Six fetal and 10 neonatal rat or mouse stomachs and a 14-week human fetal stomach were examined for immunofluorescence reactivity with four sera containing parietal cell antibody (PCA) and four other sera containing smooth muscle antibody (SMA). In rat and mouse stomachs, parietal cells first reacted with PCA in 19-da...

journal_title：Journal of clinical pathology

authors： Ceredig R,Toh BH

更新日期：1978-06-01 00:00:00

abstract：:The systematic screening of 253 children with transfusion-dependent homozygous beta-thalassaemia revealed a high incidence of hepatitis B virus markers. The highest frequencies of hepatitis B surface antigen (HBsAg) and antibody to hepatitis B core antigen (anti-HBc) were found in the group of patients with the smalle...

journal_title：Journal of clinical pathology

authors： De Virgiliis S,Fiorelli G,Fargion S,Cornacchia G,Sanna G,Cossu P,Murgia V,Cao A

更新日期：1980-10-01 00:00:00

abstract：:The prevalence of Helicobacter pylori infection in patients with Barrett's oesophagus was studied prospectively. A sensitive immunohistochemical staining of H pylori was performed in oesophageal and gastric biopsies of 73 patients from a surveillance group with this condition. H pylori was detected in 11 cases of Barr...

journal_title：Journal of clinical pathology

authors： Ricaurte O,Fléjou JF,Vissuzaine C,Goldfain D,Rotenberg A,Cadiot G,Potet F

更新日期：1996-02-01 00:00:00

abstract：:Seven commercially available screening tests for rheumatoid factor and two quantitative tests have been compared with the standard Rose-Waaler test in a series of 477 sera from patients with various joint diseases. Markedly different results were obtained, and on the basis of our findings suggestions are made as to wh...

journal_title：Journal of clinical pathology

authors： MacSween RN,Hughes H,Breen C,Kitchen P,Cathcart B,Buchanan WW

更新日期：1974-05-01 00:00:00

abstract：:A sensitive gas chromatography-mass spectrometric method was used to measure the generation in whole blood of leukotriene B4 (LTB4), a potent stimulator of neutrophil chemotaxis, in eight patients with chronic granulocytic leukaemia (CGL) and 12 healthy controls. LTB4 was detectable in unstimulated samples from all th...

journal_title：Journal of clinical pathology

authors： Reilly IA,Knapp HR,Fitzgerald GA

更新日期：1988-11-01 00:00:00

abstract：AIM:To assess the reliability of local international normalised ratios (INR) using a set of three international reference preparation (IRP) certified freeze dried plasmas. METHODS:55 centres in the United Kingdom and the Republic of Ireland participated; 36 centres employed coagulometers and 19 a manual prothrombin ti...

journal_title：Journal of clinical pathology

authors： Poller L

更新日期：1998-05-01 00:00:00

abstract：AIMS:The miR-9 family microRNAs (miRNAs) are tumour suppressor miRNAs implicated in carcinogenesis. We postulated that miR-9-1, miR-9-2 and miR-9-3 may be inactivated by aberrant promoter methylation in multiple myeloma (MM). METHODS:Methylation of miR-9-1, miR-9-2 and miR-9-3 was studied by methylation-specific PCR (...

journal_title：Journal of clinical pathology

authors： Zhang Q,Wang LQ,Wong KY,Li ZY,Chim CS

更新日期：2015-07-01 00:00:00

abstract：:A comparison is made of tests for thyroglobulin antibody, using gel diffusion, electroprecipitin, bentonite flocculation, tanned red cell agglutination, and latex slide agglutination techniques on sera from cases of Hashimoto's disease and other thyroid disorders. Any increase in gamma globulin was also noted from the...

journal_title：Journal of clinical pathology

authors： RAWSTRON JR,FARTHING CP

更新日期：1962-03-01 00:00:00

abstract：:The nasal carrier status of 3,736 patients was determined throughout their stay in hospital. The carrier rate on admission, which was highest in patients under 20 years of age, did not appear to vary with season.The carriage of strains resistant to penicillin increased with the patients' stay in hospital from 13.% on ...

journal_title：Journal of clinical pathology

authors： NOBLE WC,WILLIAMS RE,JEVONS MP,SHOOTER RA

更新日期：1964-01-01 00:00:00

abstract：BACKGROUND:Well differentiated liposarcomas (WDLPS) and dedifferentiated liposarcomas (DDLPS) have been shown to have supernumerary chromosomes with amplified sequences of the MDM2 and CDK4 genes. MDM2 and CDK4 protein overexpression have also been identified in these tumours. AIM:To investigate whether immunohistoche...

journal_title：Journal of clinical pathology

authors： Aleixo PB,Hartmann AA,Menezes IC,Meurer RT,Oliveira AM

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Although Bulgaria has one of the highest rates of cervical cancer incidence and mortality in the EU, data on HPV type distribution are limited. AIM:To determine the prevalence of HPV types 16 and 18 in archival specimens from cervical cancer cases from Bulgaria. METHODS:A total of 145 formalin-fixed, paraf...

journal_title：Journal of clinical pathology

authors： Todorova I,Ganchev G,Shikova E

更新日期：2010-12-01 00:00:00

abstract：OBJECTIVES:Intraduct papillary mucinous neoplasm (IPMN) is a pancreatic tumour that is often associated with chronic pancreatitis (CP) in the surrounding pancreas. Type 1 autoimmune pancreatitis (AIP) is a fibro-inflammatory condition with characteristic histological features and prominent IgG4+ plasma cells and is par...

journal_title：Journal of clinical pathology

authors： Bateman AC,Culver EL,Sommerlad M,Chetty R

更新日期：2013-08-01 00:00:00

abstract：:A case of coexistent acute myeloid leukaemia and sarcoidosis is reported. This was complicated by recurrent pulmonary haemorrhage during reinduction and consolidation chemotherapy. A review of published papers on malignancy and sarcoidosis, in particular acute leukaemia is given. The outcome of most cases of acute leu...

journal_title：Journal of clinical pathology

authors： Williams B,Francis A,Durrant S

更新日期：1994-07-01 00:00:00

abstract：:The cellularity of 104 primary breast carcinomata was determined by semiautomated image analysis to allow the relation between cellularity and oestrogen receptor content values to be assessed. The oestrogen receptor content of tumours detected by a steroid binding assay showed no correlation with cellularity, although...

journal_title：Journal of clinical pathology

authors： Parham DM,Baker PR,Robertson AJ,Vasishta A,Baker PG,Smith G

更新日期：1989-11-01 00:00:00

abstract：:A thin-layer chromatographic method for the simultaneous assessment of formimino-glutamic (Figlu) and urocanic acid excretion after loading with 15 g. histidine has been applied to 15 control subjects and to 49 selected patients. Upper limits of normal excretion were determined for urocanic acid and Figlu alone (15 mg...

journal_title：Journal of clinical pathology

authors： Mohamed SD,Roberts M

更新日期：1966-01-01 00:00:00

abstract：AIMS:To characterise further the proliferative compartment of the normal cervix and to document its alteration, if any, in the various grades of cervical intraepithelial neoplasia (CIN), particularly changes to the basal epithelial layer; to hypothesise as to the diagnostic and biological significance of any observed d...

journal_title：Journal of clinical pathology

authors： Payne S,Kernohan NM,Walker F

更新日期：1996-08-01 00:00:00

abstract：:Aneuploidy is frequently noted in malignant tumours. There is much controversy about its cause and effect in relation to malignant tumours. Failure of the spindle checkpoint caused by mutation of the responsible genes may be one of the important factors for the development of aneuploidy. Telomere dysfunction may also ...

journal_title：Journal of clinical pathology

authors： Dey P

更新日期：2004-12-01 00:00:00

abstract：AIMS:The aim of this study was to assess the prevalence and drug resistance of Ureaplasma species and Mycoplasma hominis in outpatients with genital manifestation from 2005 to 2013 in Hangzhou, China. METHODS:A total of 2689 female and 2336 male patients with various genital symptoms were included in this study. Speci...

journal_title：Journal of clinical pathology

authors： Song T,Ye A,Xie X,Huang J,Ruan Z,Kong Y,Song J,Wang Y,Chen J,Zhang J

更新日期：2014-09-01 00:00:00

abstract：:In a retrospective study of the records of 160 necropsies it was found that, according to the clinical and gross necropsy findings, no clinically important abnormality would have been anticipated in 46% of the tissue samples. The estimated annual cost of processing this material alone was pounds 10,500, including the ...

journal_title：Journal of clinical pathology

authors： Reid WA

更新日期：1987-04-01 00:00:00

abstract：BACKGROUND:Clinical outcome in patients with diffuse large B cell lymphomas (DLBCL) is highly variable and poorly predictable. Microarray studies showed that patients with DLBCL with a germinal centre B cell-like (GCB) phenotype have a better prognosis than those with an activated B cell-like (ABC) phenotype. The BMI1 ...

journal_title：Journal of clinical pathology

authors： van Galen JC,Muris JJ,Oudejans JJ,Vos W,Giroth CP,Ossenkoppele GJ,Otte AP,Raaphorst FM,Meijer CJ

更新日期：2007-02-01 00:00:00

abstract：AIMS:To test the hypothesis that a correct qualitative assessment of axillary nodal status can be established by examining only a limited number of lymph nodes. METHODS:Slides from 499 pN1 or pN0 axillary dissection specimens relating to symptomatic breast cancer cases operated on at our institution between 1991 and 1...

journal_title：Journal of clinical pathology

authors： Cserni G

更新日期：1999-09-01 00:00:00

abstract：AIMS:Although the autopsy is still the gold standard for quality assessment of clinical diagnoses, autopsy rates have been declining over the last decades to <10%. The aim of this study was to investigate the value of autopsies in the high-tech medicine era by determining the frequency of discrepancies between clinical...

journal_title：Journal of clinical pathology

authors： Kuijpers CC,Fronczek J,van de Goot FR,Niessen HW,van Diest PJ,Jiwa M

更新日期：2014-06-01 00:00:00

abstract：:Serum lysozyme levels were determined by a turbidometric method using egg white lysozyme as standard in 100 patients with Crohn's disease, 86 with ulcerative colitis, 31 with coeliac disease, and in 38 normal control subjects. Though the levels in Crohn's disease were significantly higher than those in ulcerative coli...

journal_title：Journal of clinical pathology

authors： Mallas E,Terry JM,Asquith P,Cooke WT

更新日期：1976-07-01 00:00:00

abstract：:A case of acute myelomonocytic leukaemia (AMMOL) is reported in which skin infiltration with xanthomatous nodules was the presenting feature. The histological, including ultrastructural, appearances are described. ...

journal_title：Journal of clinical pathology

authors： O'Donnell JR,Tansey P,Chung P,Burnett AK,Thomson J,McDonald GA

更新日期：1982-11-01 00:00:00

abstract：:The analytical goals inferred desirable by a group of clinicians for the imprecisions of a wide range of analytes have been studied by survey. The goals required have not in general become more stringent in the past decade and are not as demanding as those promulgated by laboratory professionals. Clinical biochemistry...

journal_title：Journal of clinical pathology

authors： Barrett AE,Cameron SJ,Fraser CG,Penberthy LA,Shand KL

更新日期：1979-09-01 00:00:00

abstract：:The Royal College of Pathologists (RCPath) and College of American Pathologists recommend that at least 12 lymph nodes should be harvested for adequate staging of colorectal carcinoma. Just one nodal tumour deposit upstages the malignancy from pN0 to pN1. This is critically important as node-positive patients (pN1) ar...

journal_title：Journal of clinical pathology

authors： Horne J,Bateman AC,Carr NJ,Ryder I

更新日期：2014-05-01 00:00:00

abstract：AIMS:To compare the sensitivity and specificity of new rabbit monoclonal antibody SP3 with those of mouse monoclonal and rabbit polyclonal antibodies using HER2 amplification defined by chromogenic in situ hybridisation (CISH) as the gold standard. METHODS:Serial sections from tissue microarrays (TMAs) containing 84 b...

journal_title：Journal of clinical pathology

authors： Nunes CB,Rocha RM,Reis-Filho JS,Lambros MB,Rocha GF,Sanches FS,Oliveira FN,Gobbi H

更新日期：2008-08-01 00:00:00

abstract：AIMS:To describe and evaluate two apparently unique cases of inverted hyperplastic (metaplastic) polyposis of the colon. METHODS:The cases were analysed by standard histopathological, histochemical, and immunohistochemical techniques and the findings compared with those of regular hyperplastic polyps of the colorectum...

journal_title：Journal of clinical pathology

authors： Shepherd NA

更新日期：1993-01-01 00:00:00

abstract：:Three adults with alpha 1-antitrypsin deficiency are described. In two of the cases the deficiency was genetically determined (cases 1 and 2), and each demonstrated unusual features of the disease. The liver in case 1 (homozygous) showed cholangiolar hyperplasia which has been recorded only once before. Case 2 (hetero...

journal_title：Journal of clinical pathology

authors： Sweeney EC

更新日期：1975-08-01 00:00:00