Rapid method for detecting beta-lactamase producing bacteria in clinical specimens.

abstract：BACKGROUND:Diabetes mellitus is an important diagnosis. New criteria have been defined for impaired glucose metabolism and, accordingly, there is a need for precise and accurate glucose analysis for the correct classification of patients. However, neither the World Health Organisation nor the National Service Framework...

journal_title：Journal of clinical pathology

authors： Twomey PJ

更新日期：2004-07-01 00:00:00

abstract：:Tubercle bacilli, which survived heat fixation, were detected with a slide culture technique which allowed the entire smear to be examined. Both conventional flame fixation and the use of a controlled hot-plate failed to render tuberculous sputum smears safe for further handling. Smears which were stained with the ph...

journal_title：Journal of clinical pathology

authors： Allen BW

更新日期：1981-07-01 00:00:00

abstract：:Two histochemical techniques, the PAT/KOH/PAS and the PBT/KOH/PAS, were used to investigate the side chain O-acyl substitution patterns of the sialic acids of the colonic epithelial mucins in cases of ulcerative colitis and Crohn's disease. In both diseases there was, as compared to normal, a reduction in the proporti...

journal_title：Journal of clinical pathology

authors： Culling CF,Reid PE,Dunn WL

更新日期：1979-12-01 00:00:00

abstract：:Hereditary breast cancer accounts for up to 5-10% of all breast carcinomas. Recent studies have demonstrated that mutations in two high-penetrance genes, namely BRCA1 and BRCA2, are responsible for about 16% of the familial risk of breast cancer. Even though subsequent studies have failed to find another high-penetran...

journal_title：Journal of clinical pathology

authors： Tan DS,Marchiò C,Reis-Filho JS

更新日期：2008-10-01 00:00:00

abstract：:During each of the four-year periods 1971-1975 and 1975-1979, the annual incidence of hepatitis B infection has been assessed in 56 patients with haemophilia A by measuring plasma HBsAg, anti-HBs and anti-HBc levels. Infection rates of 7% and 9.5% per annum respectively were observed for each four-year period despite ...

journal_title：Journal of clinical pathology

authors： Stirling ML,Murray JA,Mackay P,Black SH,Peutherer JF,Ludlam CA

更新日期：1983-05-01 00:00:00

abstract：:One hundred and twenty-one rectal biopsies from 99 patients with carcinoma of the rectum or lower sigmoid colon were investigated using a high iron-diamine-Alcian blue technique for sulphated and non-sulphated acid mucins. It was found that in normal rectal mucosa sulphomucins are the main carbohydrate component of th...

journal_title：Journal of clinical pathology

authors： Filipe MI

更新日期：1972-02-01 00:00:00

abstract：BACKGROUND:Mycosis fungoides (MF) is the most common skin lymphoid neoplasm. In initial stages, differential diagnosis of MF from other benign dermal lymphoid infiltrates (BDLI) may be impossible on morphological basis alone. In previous studies, only deletion of CD7 in MF proved to be of diagnostic help, but not the r...

journal_title：Journal of clinical pathology

authors： Lira M,Schenka AA,Magna LA,Cotta AC,Cintra ML,de Souza EM,Brousset P,Vassallo J

更新日期：2008-02-01 00:00:00

abstract：:A large body of evidence supports the idea that certain adult stem cells, particularly those of bone marrow origin, can engraft at alternative locations, particularly when the recipient organ is damaged. Under strong and positive selection pressure these cells will clonally expand/differentiate, making an important co...

journal_title：Journal of clinical pathology

authors： Alison MR,Poulsom R,Otto WR,Vig P,Brittan M,Direkze NC,Lovell M,Fang TC,Preston SL,Wright NA

更新日期：2004-02-01 00:00:00

abstract：:The proportion of fimbriate strains amongst Escherichia coli freshly isolated from infected urines did not differ significantly from the proportion amongst commensal Esch. coli isolated from the bowel and from non-infected urines. It is concluded that fimbriae play no major role in the pathogenesis of Esch. coli urina...

journal_title：Journal of clinical pathology

authors： Buck AC

更新日期：1967-01-01 00:00:00

abstract：UNLABELLED:Encapsulated papillary carcinoma (EPC) of the breast is a distinct histological subtype characterised by malignant epithelial proliferation supported by fibrovascular stalks. Although EPC typically lacks myoepithelial cells, it shows indolent clinical course. The classification of EPC as an in situ, or invas...

journal_title：Journal of clinical pathology

authors： Rakha EA,Tun M,Junainah E,Ellis IO,Green A

更新日期：2012-08-01 00:00:00

abstract：:This memorandum proposes a standardized system of reporting the histology of human lymph nodes based on commonly used simple staining techniques. The purpose is to provide a uniform, internationally acceptable system by which the histological structure of lymph nodes can be correlated with other parameters of immunolo...

journal_title：Journal of clinical pathology

authors： Cottier H,Turk J,Sobin L

更新日期：1973-05-01 00:00:00

abstract：AIMS:Accurate assessment of HER2 status is essential for selection of patients for HER2-targeted treatment such as trastuzumab. This study investigated the hypothesis that delayed fixation impairs HER2 assessment. METHODS:9 carcinomas were received fresh, and samples were fixed immediately or put in fixative at time i...

journal_title：Journal of clinical pathology

authors： Lee AH,Key HP,Bell JA,Kumah P,Hodi Z,Ellis IO

更新日期：2014-07-01 00:00:00

abstract：:A post-mortem examination, in the case of a 34-year-old man dying suddenly from head injuries sustained in a road accident, showed early cirrhosis of the liver and associated splenomegaly 17 years after an attack of infective hepatitis. The histology of the thymus showed abnormal changes in the medulla, consisting of ...

journal_title：Journal of clinical pathology

authors： CORRIDAN M

更新日期：1963-09-01 00:00:00

abstract：AIMS:Multiple myeloma (MM) is a heterogeneous disease characterised by genetically complex abnormalities. The classical mutational spectrum includes recurrent chromosomal aberrations and gene-level mutations. Recurrent translocations involving the IGH gene such as t(11;14), t(4;14) and t(14;16) are well known. However,...

journal_title：Journal of clinical pathology

authors： Lin M,Lee PL,Chiu L,Chua C,Ban KHK,Lin AHF,Chan ZL,Chung TH,Yan B,Chng WJ

更新日期：2018-08-01 00:00:00

abstract：:Taking a kidney biopsy is not a trivial procedure. The sample is almost invariably smaller than the pathologist would like. Investigation usually requires division into even smaller samples to permit the application of specialist techniques. In some cases the biopsy is taken not for diagnosis, but to assess the extent...

journal_title：Journal of clinical pathology

authors： Furness PN

更新日期：2000-06-01 00:00:00

abstract：:Hepatitis C virus (HCV) replication is reported in both tumour and non-tumour tissue in a case of hepatocellular carcinoma. Viral replication was established by showing the presence of minus strand HCV RNA by PCR amplification, after excluding residual reverse transcriptase activity of Taq polymerase. No minus strand ...

journal_title：Journal of clinical pathology

authors： Niu J,Kumar U,Monjardino J,Goldin R,Rosin D,Thomas HC

更新日期：1995-09-01 00:00:00

abstract：AIM:To develop a simple but reliable polymerase chain reaction (PCR) method to determine the HIV-1 status of patients on formalin fixed, paraffin wax embedded lymph node tissue. METHODS:Fifty lymph node specimens, 20 from HIV-1 seropositive and 30 from HIV-1 seronegative patients, were analysed. Lymph nodes with a var...

journal_title：Journal of clinical pathology

authors： Slavik T,Wolfaardt M,van Zyl H,Simson IW

更新日期：1995-08-01 00:00:00

abstract：AIMS:The Royal College of Pathologists recommend that a median of at least 12 lymph nodes should be harvested during pathological staging of colorectal cancer. It is not always easy to harvest the required number, especially in patients with rectal cancer receiving neoadjuvant therapy. Lymph node revealing solutions, f...

journal_title：Journal of clinical pathology

authors： Horne J,Carr NJ,Bateman AC,Kandala N 2nd,Adams J,Silva S,Ryder I

更新日期：2016-06-01 00:00:00

abstract：:Serious infection caused by Lancefield group C streptococci is unusual in man. Two unrelated deaths associated with these organisms in a 55 year old woman who died after three days of diarrhoea and vomiting, and in a 65 old man who died after a week of non-specific symptoms, are presented. Post mortem examination show...

journal_title：Journal of clinical pathology

authors： Bateman AC,Ramsay AD,Pallett AP

更新日期：1993-10-01 00:00:00

abstract：:A case of pigmented basal cell carcinoma developing in a smallpox revaccination site is presented. Any progressive change within a smallpox vaccination scar should be thoroughly evaluated and treated appropriately after tissue diagnosis. ...

journal_title：Journal of clinical pathology

authors： Rich JD,Shesol BF,Horne DW 3rd

更新日期：1980-02-01 00:00:00

abstract：AIM:To assess the ability of the commercially available monoclonal antibody 1B12 (BioGenex, San Ramon, USA) to identify C albicans in formalin fixed, paraffin wax embedded material (FFPE). METHODS:Broth cultures of 20 strains of seven Candida species were resuspended in 4% agarose blocks, fixed in formalin for 24 hour...

journal_title：Journal of clinical pathology

authors： Williams DW,Jones HS,Allison RT,Potts AJ,Lewis MA

更新日期：1998-11-01 00:00:00

abstract：:Two cases of anticonvulsant megaloblastic anaemia are described, showing features of unusual interest. Though both cases were apparently deficient in folic acid, the Figlu tests were negative. One patient had an extremely low serum B(12) concentration apparently associated with defective B(12) absorption due to defici...

journal_title：Journal of clinical pathology

authors： Reynolds EH,Hallpike JF,Phillips BM,Matthews DM

更新日期：1965-09-01 00:00:00

abstract：:Of the first 250 heart and 35 heart and lung transplant recipients at Papworth Hospital, Cambridge, who survived for more than one month after transplantation, 217 heart and 33 heart and lung patients were investigated serologically for evidence of Toxoplasma gondii infection. Six patients acquired primary T gondii in...

journal_title：Journal of clinical pathology

authors： Wreghitt TG,Hakim M,Gray JJ,Balfour AH,Stovin PG,Stewart S,Scott J,English TA,Wallwork J

更新日期：1989-02-01 00:00:00

abstract：:Routine endometrial cytology was used instead of curettage as the first step in a morphological investigation of the endometrium in patients with postmenopausal bleeding. Premenopausal women with symptoms or signs indicative of premalignant or malignant disease were also studied using this method. Patients with alarmi...

journal_title：Journal of clinical pathology

authors： Skaarland E

更新日期：1986-01-01 00:00:00

abstract：AIMS:To identify the number and geographical distribution of post mortem examinations performed on HIV infected cadavers; to identify the areas that perform post mortem examinations so that, by invitation and discussion, a national post mortem network could be initiated. METHODS:A nationwide survey of Royal College of...

journal_title：Journal of clinical pathology

authors： Davies J,Everall IP,Lantos PL

更新日期：1993-12-01 00:00:00

abstract：:Immunoreactive trypsin (IRT) content in blood spots from 17 cystic fibrosis (CF) children born between 1975-80 were assayed with reagents from two commercial radioimmunoassay kits. The manufacturers' procedures were modified to allow assay of blood spot IRT. Half of the CF samples had a significantly raised IRT conten...

journal_title：Journal of clinical pathology

authors： Ryley HC,Robinson PG,Yamashiro Y,Bradley DM

更新日期：1981-08-01 00:00:00

abstract：:Methods are described for the estimation of plasma and urine alpha-amino nitrogen by the colorimetric ninhydrin reaction; in the method for urine, both ammonia and urea are separated by a rapid ion-exchange resin procedure. Two methods of estimation are given; one has the advantage of great simplicity, but involves th...

journal_title：Journal of clinical pathology

authors： MATTHEWS DM,MUIR GG,BARON DN

更新日期：1964-03-01 00:00:00

abstract：AIM:Lymphocytic infiltration in the portal triads usually conceals the detection--in haematoxylin and eosin (H&E) stained sections--of bile ducts in two liver diseases: chronic hepatitis and primary biliary cirrhosis. The aim was to assess the number and the characteristics of the bile ducts in those diseases with the ...

journal_title：Journal of clinical pathology

authors： Rubio CA

更新日期：2000-10-01 00:00:00

abstract：INTRODUCTION:Whole slide images (WSI) have been used in many pathology applications such as teleconsultation, teaching and research, but not in primary diagnostics. The aim of this study was to test the feasibility of using WSI in primary diagnostics of paediatric pathology specimens and placental tissue. MATERIALS AN...

journal_title：Journal of clinical pathology

authors： Al-Janabi S,Huisman A,Nikkels PG,ten Kate FJ,van Diest PJ

更新日期：2013-03-01 00:00:00

abstract：:A method is described for the estimation of serum free fatty acids based on the ultramicro method of Novák. The difficulty of obtaining an accurate standard graph has been overcome and the interfering effects of phospholipids have been reduced. The method is simple to perform and gives accurate, precise results in 50 ...

journal_title：Journal of clinical pathology

authors： Elphick MC

更新日期：1968-09-01 00:00:00