Serum alanine aminotransferase (ALT) and gamma-glutamyltransferase (gamma-GT) activities in north London blood donors.

abstract：:A role has recently been assigned to cell-mediated immunity in chronic liver diseases in addition to the well-known alterations of humoral immunity. We now report the results of the rosette inhibition test for the evaluation of T-lymphocyte "sensitization" in patients with different chronic liver disorders. A cell-med...

journal_title：Journal of clinical pathology

authors： Salerno F,Fargion SR,Cappellini MD,Fiorelli G,Dioguardi N

更新日期：1976-09-01 00:00:00

abstract：AIMS:To validate the Singapore nomogram for outcome prediction in breast phyllodes tumours in a large cohort of Singaporean patients, as previous validation studies were conducted on small numbers of patients. We also investigate the association of fibroadenomas and phyllodes tumours within a subset of our cohort. MET...

journal_title：Journal of clinical pathology

authors： Chng TW,Gudi M,Lim SH,Li H,Tan PH

更新日期：2018-02-01 00:00:00

abstract：:This review deals with difficulties of diagnosis in cutaneous malignant melanoma encountered by histopathologists of variable seniority and is based on referred material at The Royal Marsden Hospital over a 20-year period and on the experience of more than two-and-a-half thousand cases referred to The World Health Org...

journal_title：Journal of clinical pathology

authors： Levene A

更新日期：1980-02-01 00:00:00

abstract：:Isolates of Campylobacter jejuni, C coli, C fetus and C laridis were tested for agglutination reactions with a panel of five lectins: Arachis hypogaea, Bauhinia purpurea, Solanum tuberosum, Triticum vulgaris and Wisteria floribunda. Twenty three patterns of agglutination (lectin types) were recorded among 376 isolates...

journal_title：Journal of clinical pathology

authors： O'Sullivan N,Benjamin J,Skirrow MB

更新日期：1990-11-01 00:00:00

abstract：:Recent evidence shows that chronic liver disease induced by hepatitis delta virus is closely associated with production of autoantibodies. To verify this sera from patients with hepatitis delta virus and from those with hepatitis B virus mediated chronic liver disease were tested for a panel of autoantibodies. Althoug...

journal_title：Journal of clinical pathology

authors： Zauli D,Crespi C,Bianchi FB,Craxi A,Pisi E

更新日期：1986-08-01 00:00:00

abstract：AIMS:To evaluate a recently developed digital slide and virtual microscope system, and to compare this method with optical microscopy on routine gastrointestinal biopsy specimens in both local and remote access modes. METHODS:A fully computer controlled commercial microscope was used. The scanning program included obj...

journal_title：Journal of clinical pathology

authors： Molnar B,Berczi L,Diczhazy C,Tagscherer A,Varga SV,Szende B,Tulassay Z

更新日期：2003-06-01 00:00:00

abstract：:This report describes the case of a 76 year old man who suffered from febrile ulceronecrotic Mucha-Habermann disease (FUMHD). Despite this patient's typical clinical and histological findings, the fulminating course led to death. Polymerase chain reaction (PCR) analysis of the skin lesions showed that the infiltrating...

journal_title：Journal of clinical pathology

authors： Miyamoto T,Takayama N,Kitada S,Hagari Y,Mihara M

更新日期：2003-10-01 00:00:00

abstract：:The titre of antibodies to Toxoplasma gondii was compared in 1985 sera by use of an indirect haemagglutination test (ToxHA test--Wellcome Reagents Ltd) and the dye test. Sera from 42 patients with clinical or serological indications of recent toxoplasmosis were also examined to determine if the ToxHA test would be of ...

journal_title：Journal of clinical pathology

authors： Balfour AH,Bridges JB,Harford JP

更新日期：1980-07-01 00:00:00

abstract：:Assessment of ERBB2 (HER2) status in breast carcinomas has become critical in determining response to the humanised monoclonal antibody trastuzumab. The current joint College of American Pathologists and the American Society of Clinical Oncology guidelines for the evaluation of HER2 status in breast carcinoma involve ...

journal_title：Journal of clinical pathology

authors： Gruver AM,Peerwani Z,Tubbs RR

更新日期：2010-03-01 00:00:00

abstract：AIMS:N-terminal pro-B-type natriuretic peptide (NT-proBNP) has been shown to be useful for ruling out heart failure in primary care. In this study, we examined the accuracy of the Cobas h232 point-of-care (POC) instrument in primary care compared with an in-hospital measurement. Furthermore, we investigated the user-fr...

journal_title：Journal of clinical pathology

authors： Hex C,Smeets M,Penders J,Van Hoof V,Verbakel J,Buntinx F,Vaes B

更新日期：2018-06-01 00:00:00

abstract：:The prevalence of Helicobacter pylori infection in patients with Barrett's oesophagus was studied prospectively. A sensitive immunohistochemical staining of H pylori was performed in oesophageal and gastric biopsies of 73 patients from a surveillance group with this condition. H pylori was detected in 11 cases of Barr...

journal_title：Journal of clinical pathology

authors： Ricaurte O,Fléjou JF,Vissuzaine C,Goldfain D,Rotenberg A,Cadiot G,Potet F

更新日期：1996-02-01 00:00:00

abstract：:Chromosome studies were attempted on 97% of necropsies carried out in the Department of Histopathology of the Adelaide Children's Hospital over the four-year period ending May 1981. Results were obtained from 89% of necropsies of which 7.5% had major chromosome abnormalities. The chromosome results are analysed accord...

journal_title：Journal of clinical pathology

authors： Sutherland GR,Carter RF

更新日期：1983-02-01 00:00:00

abstract：BACKGROUND/AIMS:Mast cells, when activated, secrete a large number of fibrogenic factors and have been implicated in the development of fibrotic conditions of the liver, lung, and skin. There is evidence that renal fibrosis is closely linked with a chronic inflammatory cell infiltrate within the interstitium, but a pot...

journal_title：Journal of clinical pathology

authors： Roberts IS,Brenchley PE

更新日期：2000-11-01 00:00:00

abstract：:A knowledge-based computer system, designed to assist pathologists in the histological diagnosis of breast disease, is described. This system represents knowledge in the form of "disease profiles" and uses a novel inference model based on the mathematical technique of hypergraphs. Its design overcomes many of the limi...

journal_title：Journal of clinical pathology

authors： Heathfield H,Bose D,Kirkham N

更新日期：1991-06-01 00:00:00

abstract：AIMS:To establish whether abnormalities in the course of the vertebral artery occur and whether they are relevant to arterial injury associated with head and neck movements. METHODS:Twenty vertebral arteries were carefully dissected at necropsy and abnormalities in course were noted, along with any other bony or carti...

journal_title：Journal of clinical pathology

authors： Johnson CP,Scraggs M,How T,Burns J

更新日期：1995-07-01 00:00:00

abstract：:Electron microscopical and cytochemical studies of intestinal biopsies from a patient with typical features of the Cronkhite-Canada syndrome show that the primary process affects the crypts. This results in cystic dilatation associated with expansion and focal degeneration of the crypt compartment of the intestinal ep...

journal_title：Journal of clinical pathology

authors： Jenkins D,Stephenson PM,Scott BB

更新日期：1985-03-01 00:00:00

abstract：AIM:To investigate whether there is loss of the p27Kip1 protein in developing cervical cancer and whether p27Kip1 immunoreactivity has any relation to the proliferative indicator Ki-67. METHODS:The expression of p27Kip1 and Ki-67 was assessed by immunohistochemistry in serial sections from normal epithelium (13), low ...

journal_title：Journal of clinical pathology

authors： Troncone G,Vetrani A,de Rosa G,Gerbasio D,Palombini L

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:Many patients with advanced cancer are malnourished. Anorexia is common, as is the use of chemotherapy, which may cause nausea and poor appetite. Ten per cent of these patients experience haemorrhagic events. AIM:Since vitamin K deficiency (VKD) causes bleeding, to establish the prevalence of VKD in patient...

journal_title：Journal of clinical pathology

authors： Harrington DJ,Western H,Seton-Jones C,Rangarajan S,Beynon T,Shearer MJ

更新日期：2008-04-01 00:00:00

abstract：:The clinical and pathological features of a case of malakoplakia of the adrenal gland occurring in a woman with Escherichia coli infection are described. This lesion mimicked a neoplasm, the true diagnosis only being revealed by histological examination. The light and electron microscopic features are described and it...

journal_title：Journal of clinical pathology

authors： Benjamin E,Fox H

更新日期：1981-06-01 00:00:00

abstract：:Seven commercially available screening tests for rheumatoid factor and two quantitative tests have been compared with the standard Rose-Waaler test in a series of 477 sera from patients with various joint diseases. Markedly different results were obtained, and on the basis of our findings suggestions are made as to wh...

journal_title：Journal of clinical pathology

authors： MacSween RN,Hughes H,Breen C,Kitchen P,Cathcart B,Buchanan WW

更新日期：1974-05-01 00:00:00

abstract：INTRODUCTION:Bone marrow aspiration and biopsy is an invasive procedure associated with morbidity and mortality risk. We compared a powered bone marrow aspiration and biopsy device to the traditional method by relatively assessing pain scores, procedure times, biopsy capture rates, quality of material retrieved, and sa...

journal_title：Journal of clinical pathology

authors： Swords RT,Anguita J,Higgins RA,Yunes AC,Naski M,Padmanabhan S,Kelly KR,Mahalingam D,Philbeck T,Miller L,Puga TA,Giles FJ,Kinney MC,Brenner AJ

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:The Royal College of Pathologists introduced the National Minimum Dataset (NMDS) for the histopathological reporting of cutaneous melanoma in February 2002. AIM:To determine if histological reporting of invasive primary cutaneous melanoma in the West Midlands region of the UK was compliant with the NMDS. M...

journal_title：Journal of clinical pathology

authors： Kaur MR,Colloby PS,Martin-Clavijo A,Marsden JR

更新日期：2007-10-01 00:00:00

abstract：:Three patients with aplastic anaemia had a history of substantial previous exposure to organochlorine pesticides. The temporal association between chemical exposure and the onset of first symptoms of anaemia was strongly supportive. Organochlorines have the property of lipid affinity and accumulation in adipose tissue...

journal_title：Journal of clinical pathology

authors： Rugman FP,Cosstick R

更新日期：1990-02-01 00:00:00

abstract：:The usefulness of placental alkaline phosphatase (PLAP) as a diagnostic marker of malignancy was assessed in pleural fluid from 60 patients with effusions. Pleural fluid PLAP activities were measured by an enzyme linked immunoassay (ELISA) using the two monoclonal antibodies H17E2 and H317. Similar values were found i...

journal_title：Journal of clinical pathology

authors： Fergusson RJ,Fisken J,McIntyre MA,Roulston JE,Leonard RC

更新日期：1992-12-01 00:00:00

abstract：BACKGROUND:Nitric oxide synthase (NOS), particularly endothelial and inducible forms (e/i-NOS), are expressed in various cancers, including breast cancer. In mammary fibroepithelial lesions, NOS expression in stromal cells has been reported to be lower in fibroadenomas than in phyllodes tumours. AIMS:To investigate NO...

journal_title：Journal of clinical pathology

authors： Tse GM,Wong FC,Tsang AK,Lee CS,Lui PC,Lo AW,Law BK,Scolyer RA,Karim RZ,Putti TC

更新日期：2005-06-01 00:00:00

abstract：:Taking a kidney biopsy is not a trivial procedure. The sample is almost invariably smaller than the pathologist would like. Investigation usually requires division into even smaller samples to permit the application of specialist techniques. In some cases the biopsy is taken not for diagnosis, but to assess the extent...

journal_title：Journal of clinical pathology

authors： Furness PN

更新日期：2000-06-01 00:00:00

abstract：AIMS:Iron overload is a major factor contributing to the overall pathology of thalassaemia, which is primarily mediated by ineffective erythropoiesis and shorter mature red blood cell (RBC) survival. Iron accumulation in RBCs generates reactive oxygen species (ROS) that cause cellular damage such as lipid peroxidation ...

journal_title：Journal of clinical pathology

authors： Chaichompoo P,Qillah A,Sirankapracha P,Kaewchuchuen J,Rimthong P,Paiboonsukwong K,Fucharoen S,Svasti S,Worawichawong S

更新日期：2019-08-01 00:00:00

abstract：OBJECTIVE:To study the expression of nuclear beta-catenin and Ki-67 in patients with normal gestation products (NGP), complete hydatidiform moles (CHM), and choriocarcinoma to elucidate their roles in carcinogenesis and their interrelations. METHODS:Expression of nuclear beta-catenin and Ki-67 was studied by immunohis...

journal_title：Journal of clinical pathology

authors： Wong SC,Chan AT,Chan JK,Lo YM

更新日期：2006-04-01 00:00:00

abstract：:Reticulin antibodies have been classified by immunofluorescence into five types reacting with distinct antigens of intra- and extracellular components in mesenchyme. Two types of fibrillar antigens can be distinguished on the basis of the staining patterns, anatomical distribution, and species specificity. A third ant...

journal_title：Journal of clinical pathology

authors： Rizzetto M,Doniach D

更新日期：1973-11-01 00:00:00

abstract：:Three strains of Past. septica were isolated in Hong Kong. The clinical histories and the detailed bacteriological and serological studies are presented. ...

journal_title：Journal of clinical pathology

authors： WONG PC,CHAN-TEOH CH

更新日期：1964-03-01 00:00:00