Use of morphometry in cytological preparations for diagnosing follicular non-Hodgkin's lymphomas.

abstract：:A case of extramedullary myeloblastic transformation of chronic myeloid leukaemia is reported. This was characterised by an unusual clinical and haematological course and showed a unique cytogenetic pattern. ...

journal_title：Journal of clinical pathology

authors： Flanagan NG,Harrison CJ,Harry DS,Ridway JC

更新日期：1985-07-01 00:00:00

abstract：:Experiments were performed to evaluate five commercial kit assays used for the detection of antibodies to dsDNA. The kits were compared using a performance index score as recommended by the guidelines of the European Committee for Clinical Laboratory Standards. The highest performance score was obtained using the radi...

journal_title：Journal of clinical pathology

authors： McMillan SA,Fay AC

更新日期：1988-11-01 00:00:00

abstract：:Tumour associated antigens recognised by cellular or humoral effectors of the immune system are potential targets for antigen specific cancer immunotherapy. Different categories of cancer antigens have been identified that induce cytotoxic T lymphocyte (CTL) responses in vitro and in vivo, namely: (1) "cancer testis" ...

journal_title：Journal of clinical pathology

authors： Jäger D,Jäger E,Knuth A

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:Some uterine endometrioid adenocarcinomas exhibit a distinctive morphological phenotype characterised by the formation of microcystic, elongated and fragmented (MELF) glands. Immunohistochemical studies have suggested that MELF-type changes represent an epithelial-mesenchymal transition which has been associ...

journal_title：Journal of clinical pathology

authors： Stewart CJ,Amanuel B,Grieu F,Carrello A,Iacopetta B

更新日期：2010-07-01 00:00:00

abstract：:Antral biopsy culture supernatants from 14 subjects with chronic gastritis, known to have IgA antibodies to the 120 kilodalton protein, showed positive recognition of this antigen in western blots against a cytotoxin positive strain of Helicobacter pylori but gave negative reactions with two cytotoxin negative strains...

journal_title：Journal of clinical pathology

authors： Crabtree JE,Figura N,Taylor JD,Bugnoli M,Armellini D,Tompkins DS

更新日期：1992-08-01 00:00:00

abstract：:Superficial inflammatory dermatoses are very common and comprise a wide, complex variety of clinical conditions. Accurate histological diagnosis, although it can sometimes be difficult to establish, is essential for clinical management. Knowledge of the microanatomy of the skin is important to recognise the variable h...

journal_title：Journal of clinical pathology

authors： Alsaad KO,Ghazarian D

更新日期：2005-12-01 00:00:00

abstract：:Apocrine morphology is a common phenomenon encountered in everyday breast pathology practice, and is defined as cuboidal or columnar cells exhibiting abundant eosinophilic granular cytoplasm, prominent apical granules, a low nuclear-cytoplasmic ratio, and round nuclei with pale chromatin and prominent nucleoli. Apocri...

journal_title：Journal of clinical pathology

authors： D'Arcy C,Quinn C

更新日期：2019-01-01 00:00:00

abstract：:Evaluation of histological diagnosis requires an index of agreement (to measure repeatability and validity) together with a method of assessing bias. Cohen's kappa statistic appears to be the most suitable tool for measuring levels of agreement, which if unsatisfactory may be caused by bias. Further study of bias is p...

journal_title：Journal of clinical pathology

authors： Silcocks PB

更新日期：1983-11-01 00:00:00

abstract：AIMS:Apoptosis in prostate cancer was evaluated after three months of combined endocrine therapy to investigate the association with tumour grade, tumour stage, and the immunohistochemical detection of p53 and bcl-2 in tumour cells before and after therapy. METHODS:Twenty six formalin fixed, paraffin wax embedded core...

journal_title：Journal of clinical pathology

authors： Colecchia M,Frigo B,Del Boca C,Guardamagna A,Zucchi A,Colloi D,Leopardi O

更新日期：1997-05-01 00:00:00

abstract：:An alternative method for detecting the production of slime by coagulase negative staphylococci was compared with the routinely used Christensen method on 124 isolates of coagulase negative staphylococci from carriage sites, blood cultures, and infected peritoneal dialysis fluids. The alternative method requires the u...

journal_title：Journal of clinical pathology

authors： Freeman DJ,Falkiner FR,Keane CT

更新日期：1989-08-01 00:00:00

abstract：AIMS:To investigate the role of needle core biopsy (NCB) in the preoperative assessment of impalpable breast lesions, mainly derived from the NHS Breast Screening Programme (NHSBSP) and to assess our own modifications to a suggested system for the classification of breast NCBs. METHODS:The NCB, fine needle aspiration ...

journal_title：Journal of clinical pathology

authors： Ibrahim AE,Bateman AC,Theaker JM,Low JL,Addis B,Tidbury P,Rubin C,Briley M,Royle GT

更新日期：2001-02-01 00:00:00

abstract：:Human papillomavirus (HPV) infection of cervical intraepithelial neoplasia (CIN) and invasive cervical carcinoma was investigated using in situ DNA-DNA hybridisation on histological sections of formalin fixed, paraffin embedded tissue to assess the technique's sensitivity and to assess retrospectively the association ...

journal_title：Journal of clinical pathology

authors： Collins JE,Jenkins D,McCance DJ

更新日期：1988-03-01 00:00:00

abstract：:Only four cases of tracheopathia osteoplastica have been reported in Britain in the past 110 years. Ten further cases are now reported; in two the diagnosis was made at bronchoscopy. It is suggested that the reputed rarity of the condition in Britain is not the whole picture. ...

journal_title：Journal of clinical pathology

authors： Way SP

更新日期：1967-11-01 00:00:00

abstract：:Serial dilutions of Clostridium difficile culture filtrates were incubated overnight with HeLa cell monolayers. Cells were fixed in formalin, stained with crystal violet, rinsed, and drained. Cell rounding could be observed microscopically in the stained monolayers. Absorbance of the retained dye on monolayers in the ...

journal_title：Journal of clinical pathology

authors： Rothman SW

更新日期：1986-06-01 00:00:00

abstract：:Clonality analysis of the immunoglobulin heavy chain (IgH) gene is helpful in identifying malignant B cell infiltrates in the bone marrow and is usually carried out on separate aspirates or on the same formalin-fixed decalcified bone marrow specimen. To determine whether the removal of the decalcification step would i...

journal_title：Journal of clinical pathology

authors： Parrens M,Carrere N,Bouabdallah K,Fitoussi O,Goussot JF,Dubus P,de Mascarel A,Merlio JP

更新日期：2006-10-01 00:00:00

abstract：:Twelve methods for the demonstration of bacterial penicillinase production by strains of Haemophilus influenzae and Staphylococcus aureus are compared, and their suitability for routine clinical laboratory use is evaluated. The acidometric agar plate method is recommended. ...

journal_title：Journal of clinical pathology

authors： Lucas TJ

更新日期：1979-10-01 00:00:00

abstract：:Platelet adhesiveness has been assessed on whole blood from a series of 34 diabetics and 50 control subjects using adenosine diphosphate (A.D.P.) and by adherence to glass microspherules (ballotini). Using both techniques it was possible to demonstrate a significant increase in platelet adhesiveness in the diabetic pa...

journal_title：Journal of clinical pathology

authors： Shaw S,Pegrum GD,Wolff S,Ashton WL

更新日期：1967-11-01 00:00:00

abstract：:In two families with severe sex-linked muscular dystrophy, high levels of alpha-hydroxybutyrate dehydrogenase (HBD), lactate dehydrogenase (LD), aspartate transaminase (AspT), aldolase, and creatine phosphokinase (CPK) were found in the sera of three young affected males. In both families the mother had a raised level...

journal_title：Journal of clinical pathology

authors： Johnston HA,Wilkinson JH,Withycombe WA,Raymond S

更新日期：1966-05-01 00:00:00

abstract：:A questionnaire was circulated to clinical biochemistry laboratories in the North West Thames region of the United Kingdom requesting information on extralaboratory equipment. Data on the types and numbers of instruments in use, their relationship with the laboratory, and quality assurance procedures were obtained. La...

journal_title：Journal of clinical pathology

authors： Burrin JM,Fyffe JA

更新日期：1988-09-01 00:00:00

abstract：AIMS:To determine the possible histogenesis of the intracranial variant of olfactory neuroblastoma. METHODS:Four specimens from three cases of intracranial olfactory neuroblastoma were studied by light microscopy and immuno-histochemistry, and electron microscopy in two cases. RESULTS:Light microscopical examination ...

journal_title：Journal of clinical pathology

authors： Banerjee AK,Sharma BS,Vashista RK,Kak VK

更新日期：1992-04-01 00:00:00

abstract：AIMS:To determine whether Ki-67 immunoexpression in penile squamous cell carcinoma (PSCC) has a prognostic value and correlates with lymph node metastasis, human papillomavirus (HPV) infection and patient survival. METHODS:148 formalin-fixed paraffin-embedded PSCC samples were tissue-microarrayed, including 97 usual-t...

journal_title：Journal of clinical pathology

authors： Stankiewicz E,Ng M,Cuzick J,Mesher D,Watkin N,Lam W,Corbishley C,Berney DM

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Chromogenic in situ hybridisation (CISH) is an alternative to immunohistochemistry or FISH for the assessment of HER2 oncogene status in breast cancer. Although CISH is being used increasingly in routine diagnostics, there are no established inter-laboratory quality assurance programmes for this test. METHO...

journal_title：Journal of clinical pathology

authors： Di Palma S,Collins N,Bilous M,Sapino A,Mottolese M,Kapranos N,Schmitt F,Isola J

更新日期：2008-06-01 00:00:00

abstract：AIMS:To investigate the morphological and histopathological associations between an individual pit seen on stereomicroscopy or magnifying colonoscopy and an individual crypt seen in histological sections; and to examine these associations in colorectal tumours. METHODS:Fourteen thousand and twenty three cases were exa...

journal_title：Journal of clinical pathology

authors： Kudo S,Hirota S,Nakajima T,Hosobe S,Kusaka H,Kobayashi T,Himori M,Yagyuu A

更新日期：1994-10-01 00:00:00

abstract：:Sixty-nine specimens of liver tissue from 53 infants with neonatal hepatitis or its sequelae were examined without knowledge of the alpha1-antitrypsin phenotype. Distinctive, diastase-resistant, PAS-positive, pure magenta-coloured, sharply defined globules, 2-20 microns in diameter were found in periportal and parasep...

journal_title：Journal of clinical pathology

authors： Talbot IC,Mowat AP

更新日期：1975-07-01 00:00:00

abstract：:Escherichia coli O157:H7 was isolated from a fatal case of haemorrhagic colitis with haemolytic uraemic syndrome and neurological symptoms. This strain induced diarrhoea and neurological symptoms including incoordination, ataxia, and convulsions in piglets after oral inoculation. Similar neurological signs were seen i...

journal_title：Journal of clinical pathology

authors： Tzipori S,Chow CW,Powell HR

更新日期：1988-10-01 00:00:00

abstract：:As part of a study to establish the prevalence of renal calculus disease, alkaline phosphatase activity was measured by the method recommended by the Scandinavian Society for Clinical Chemistry and Clinical Physiology in the plasma of 3823 adults from the Scottish new town of Cumbernauld. The enzyme activity differs i...

journal_title：Journal of clinical pathology

authors： Gardner MD,Scott R

更新日期：1978-12-01 00:00:00

abstract：:Rates of urinary excretion concomitant with the molecular size distribution of filtered polymer fragments were determined in five normovolaemic men dosed with 30 g/m2 BSA of a species of HES (HES 350/0.60) possessing a M-W of 350 000 combined with an MS of 0.60. Approximately 13% of the total injected dose of HES 350/...

journal_title：Journal of clinical pathology

authors： Mishler JM,Ricketts CR,Parkhouse EJ

更新日期：1981-04-01 00:00:00

abstract：:If native or heparinized blood is passed slowly through a column of glass beads at room temperature, the number of platelets removed from the initial drop emerging from the column is less than that removed from the final drop. At 4 degrees C. this difference disappears. If the blood is passed rapidly through such colu...

journal_title：Journal of clinical pathology

authors： O'Brien JR,Heywood JB

更新日期：1967-01-01 00:00:00

abstract：:A case of cirrhosis of the liver, associated with false-positive serological tests for syphilis and an antibody active against stored red cells, is presented. Methods used in the identification of the ;stored red cell' antibody are described. ...

journal_title：Journal of clinical pathology

authors： EASTON JA,PRIEST CJ,GILES CM

更新日期：1965-07-01 00:00:00

abstract：AIM:The evaluation of allelic losses at the FHIT and the BRCA1 genes and at three other loci at the 17q region in a series of 34 sporadic breast cancer cases from Southern Brazil. METHODS:The samples were evaluated for loss of heterozygosity (LOH) at the FHIT and the BRCA1 genes and at three other microsatellite marke...

journal_title：Journal of clinical pathology

authors： Santos SC,Cavalli LR,Cavalli IJ,Lima RS,Haddad BR,Ribeiro EM

更新日期：2004-04-01 00:00:00