New method for detecting slime production by coagulase negative staphylococci.

abstract：:Hereditary breast cancer accounts for up to 5-10% of all breast carcinomas. Recent studies have demonstrated that mutations in two high-penetrance genes, namely BRCA1 and BRCA2, are responsible for about 16% of the familial risk of breast cancer. Even though subsequent studies have failed to find another high-penetran...

journal_title：Journal of clinical pathology

authors： Tan DS,Marchiò C,Reis-Filho JS

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND/AIMS:In the natural history of gastric cancer, non-invasive neoplasia (NiN) precedes invasive carcinoma. A histological classification of gastric NiN has recently been proposed by a World Health Organisation international panel of experts. Genetic instability is known to be among the molecular pathways invol...

journal_title：Journal of clinical pathology

authors： Rugge M,Bersani G,Bertorelle R,Pennelli G,Russo VM,Farinati F,Bartolini D,Cassaro M,Alvisi V

更新日期：2005-08-01 00:00:00

abstract：:Three selective chromogenic culture media (CHROMagars ESBL, CTX-M and KPC) were evaluated for their ability to support the growth of nine Klebsiella pneumoniae isolates producing OXA-48 carbapenemase in combination with other β-lactamases. CHROMagar ESBL and CHROMagar KPC were the most sensitive media, supporting grow...

journal_title：Journal of clinical pathology

authors： Hornsey M,Phee L,Woodford N,Turton J,Meunier D,Thomas C,Wareham DW

更新日期：2013-04-01 00:00:00

abstract：:A rapid and reproducible electrophoretic method for the separation and quantitation of haemoglobins on cellulose acetate is described. The accuracy of the method and its possible sources of error are discussed. The normal range for haemoglobin A(2) by this method is 1% to 3% of the total haemoglobin concentration. Blo...

journal_title：Journal of clinical pathology

authors： Marengo-Rowe AJ

更新日期：1965-11-01 00:00:00

abstract：:Haemoglobin, haematocrit, and plasma iron values were estimated on blood samples collected from 100 male and 113 female National Blood Transfusion Service blood donors, and from 83 male and 66 female age-matched control subjects. No significant differences in any of these values were found to exist between the donors ...

journal_title：Journal of clinical pathology

authors： French EA,Sitlani PK

更新日期：1969-11-01 00:00:00

abstract：BACKGROUND:Prostate cancer diagnosis is routinely made by the histopathological examination of formalin fixed needle biopsy specimens. Frequently this is the only cancer tissue available from the patient for the analysis of diagnostic and prognostic biomarkers. There is, therefore, an urgent need for methods that allow...

journal_title：Journal of clinical pathology

authors： McCarthy F,Fletcher A,Dennis N,Cummings C,O'Donnell H,Clark J,Flohr P,Vergis R,Jhavar S,Parker C,Cooper CS

更新日期：2009-08-01 00:00:00

abstract：:Large cell neuroendocrine carcinoma (LCNEC) is a high grade type of neuroendocrine tumour with an aggressive clinical course. This report describes the first case of LCNEC combined with an adenocarcinoma component in the common bile duct. A 68 year old man presented with jaundice. Severe stenosis of the bile duct was ...

journal_title：Journal of clinical pathology

authors： Sato K,Waseda R,Tatsuzawa Y,Fujinaga H,Wakabayashi T,Ueda Y,Katsuda S

更新日期：2006-01-01 00:00:00

abstract：:A correlative clinical and Hemalog D study of 80 cases of chronic lymphocytic leukaemia (CLL) was performed and the results compared with those in other lymphoproliferative disorders affecting the blood (eight cases of hairy-cell leukaemia, HCL; three cases of prolymphocytic leukaemia, PLL: two cases of lymphoplasmacy...

journal_title：Journal of clinical pathology

authors： Patterson KG,Goldstone AH,Richards JD,Cawley JC

更新日期：1981-05-01 00:00:00

abstract：:Liver diseases are associated with complex haemostasis defects, in which platelets, coagulation, and fibrinolysis may all be affected. The low plasma concentrations of clotting factors often found can be the result of many changes such as impaired synthesis, increased catabolism due to intravascular coagulation, or al...

journal_title：Journal of clinical pathology

authors： Knot E,Ten Cate JW,Drijfhout HR,Kahlé LH,Tytgat GN

更新日期：1984-05-01 00:00:00

abstract：:Fluorescence in situ hybridisation (FISH) analysis is now widely employed in the diagnosis and risk stratification of a wide range of malignant diseases. While this technique is used successfully with formalin-fixed paraffin-embedded (FFPE) sections from numerous tissue types, FISH analysis of FFPE tissue sections fro...

journal_title：Journal of clinical pathology

authors： Neat MJ,Moonim MT,Dunn RG,Geoghegan H,Foot NJ

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Well differentiated liposarcomas (WDLPS) and dedifferentiated liposarcomas (DDLPS) have been shown to have supernumerary chromosomes with amplified sequences of the MDM2 and CDK4 genes. MDM2 and CDK4 protein overexpression have also been identified in these tumours. AIM:To investigate whether immunohistoche...

journal_title：Journal of clinical pathology

authors： Aleixo PB,Hartmann AA,Menezes IC,Meurer RT,Oliveira AM

更新日期：2009-12-01 00:00:00

abstract：:A Cyto-Tek staining machine designed for Papanicolau staining of cervical smears has been adapted for auramine staining of smears of sputum and other clinical specimens for acid-fast bacilli. The results compared favourably with those obtained by a manual method of staining. Contamination of negative smears by acid-fa...

journal_title：Journal of clinical pathology

authors： Heimer GV,Joseph N,Taylor CE

更新日期：1978-02-01 00:00:00

abstract：:In all cases of primary endocardial fibroelastosis investigated diffuse degenerative changes in the ganglion cells were detected. Thickened endocardium was formed by the proliferation of mesenchymal cells located under the endothelial endocardium and of the mesenchyme surrounding the necrobiotic muscle cells. In some ...

journal_title：Journal of clinical pathology

authors： Zóltowska A

更新日期：1971-04-01 00:00:00

abstract：:Platelet concentrates were prepared for in vitro storage in either Fenwal PL-732 or Cutter CLX platelet packs. The units were stored at 22 degrees C for seven days with either horizontal or tumbler agitation. Measurement of pH, hypotonic shock response and serotonin uptake indicated in vitro viability was well maintai...

journal_title：Journal of clinical pathology

authors： Taylor MA,Tandy NP,Fraser ID

更新日期：1983-12-01 00:00:00

abstract：:A blood group change from A2 to Ax is described in a boy who had Fallot's tetralogy, oesophageal atresia, and a tracheo-oesophageal fistula. The change of blood group created a transfusion problem. The unusual serology is discussed. ...

journal_title：Journal of clinical pathology

authors： Bird GW,Roberts KD,Wingham J

更新日期：1975-12-01 00:00:00

abstract：AIM:The prognostic significance of perineural invasion (PNI) in oesophageal adenocarcinoma (EAC) is unclear. We examined the association of PNI with clinical outcomes in patients treated with neoadjuvant chemoradiotherapy (nCRT) and surgery. METHODS:We performed a single institutional retrospective study. We evaluated...

journal_title：Journal of clinical pathology

authors： Patel AK,Pan X,Vila DM,Frankel WL,Chen W,Perry KA,Merritt RE,D'Souza DM,Wuthrick EJ,Williams TM

更新日期：2020-04-21 00:00:00

abstract：:A modified nitroblue tetrazolium test (NBT) is described which is suitable for routine application in the haematology or bacteriology laboratory and which provides a rapid aid to the diagnosis of bacterial infection. Hitherto published methods have recommended the use of heparinized whole blood samples for the perform...

journal_title：Journal of clinical pathology

authors： Gordon AM,Rowan RM,Brown T,Carson HG

更新日期：1973-01-01 00:00:00

abstract：AIMS:Diffuse large B-cell lymphoma (DLBCL) is an aggressive and potentially fatal disease. Prediction of risk of relapse is based on clinical markers. There is a need for more accurate biomarkers to select patients for more aggressive first-line treatments. Peroxiredoxins (Prxs) are a family of potent antioxidant prote...

journal_title：Journal of clinical pathology

authors： Kuusisto ME,Haapasaari KM,Turpeenniemi-Hujanen T,Jantunen E,Soini Y,Peroja P,Bloigu R,Karihtala P,Kuittinen O

更新日期：2015-07-01 00:00:00

abstract：:Patients with bacterial infection may show altered membrane permeability of the primary azurophilic lysosomes of blood neutrophils. A new enzyme cytochemical technique, sensitive to increased membrane permeability caused by contact of neutrophils with acetone, saponin, low pH, Streptolysin O, bacteria, and nylon wool,...

journal_title：Journal of clinical pathology

authors： Wozniak JT,Orchard TL,Mackie PH,Mistry DK,Stuart J

更新日期：1978-07-01 00:00:00

abstract：:The activities of phosphohexose isomerase and 6-phosphogluconate dehydrogenase have been studied in the vaginal fluid of women from the gynaecological departments. Women from these departments gave a very high false positive rate, though no cases of carcinoma in situ were not detected by estimating phosphohexose isome...

journal_title：Journal of clinical pathology

authors： Muir GG

更新日期：1966-07-01 00:00:00

abstract：:Eight isolates of C. albicans were used to determine the frequency with which germ tube formation occurred: on rice extract -Tween 80 agar, on its components, and on 1% bactopeptone agar after three hr at 37 degrees C; in 0.5% aqueous solution of various carbohydrates; in various concentrations of glucose; on 0.5 and ...

journal_title：Journal of clinical pathology

authors： Joshi KR,Bremner DA,Parr DN,Gavin JB

更新日期：1975-01-01 00:00:00

abstract：:Endocardial fibroelastosis, defined as an endocardium in excess of 30 microns thick, was found in 10 out of 34 cases of hydrops fetalis in a review of 1589 perinatal necropsies carried out between 1976 and 1989. The infants comprised 16 cases of rhesus haemolytic disease, of whom three had endocardial fibroelastosis, ...

journal_title：Journal of clinical pathology

authors： Newbould MJ,Armstrong GR,Barson AJ

更新日期：1991-07-01 00:00:00

abstract：AIMS:To evaluate the influence of involvement of the peritoneal surface by carcinoma of the rectum on local recurrence and prognosis. METHODS:Prospective analysis of pathological prognostic factors in 209 resections for rectal carcinoma between 1988 and 1993 with meticulous pathological technique particularly to asses...

journal_title：Journal of clinical pathology

authors： Shepherd NA,Baxter KJ,Love SB

更新日期：1995-09-01 00:00:00

abstract：:Gastroblastoma is a rare gastric epitheliomesenchymal biphasic tumour composed of spindle and epithelial cells, reported by Miettinen et al in a series of three cases in 2009. All those cases arose in stomachs of young adults. Neither the epithelial nor the mesenchymal component displayed sufficient atypia to diagnose...

journal_title：Journal of clinical pathology

authors： Shin DH,Lee JH,Kang HJ,Choi KU,Kim JY,Park DY,Lee CH,Sol MY,Park JH,Kim HY,Montgomery E

更新日期：2010-03-01 00:00:00

abstract：AIMS:To study the pathogenicity and virulence characteristics of Staphylococcus epidermidis, Staphylococcus haemolyticus, and Staphylococcus sapro-phyticus. METHODS:BALB/c mice were challenged intraperitoneally with graded doses of three strains belonging to each species. LD50s were measured for each strain. Haemolysi...

journal_title：Journal of clinical pathology

authors： Molnàr C,Hevessy Z,Rozgonyi F,Gemmell CG

更新日期：1994-08-01 00:00:00

abstract：:Isolates of Bacillus cereus from 118 cases, and two maternity unit outbreaks, of non-gastrointestinal infection were grouped on the basis of their estimated probable involvement in the infections from which they were isolated: (i) high probability--48 strains; (ii) intermediate--16 strains; (iii) low--7 strains; (iv) ...

journal_title：Journal of clinical pathology

authors： Turnbull PC,Kramer JM

更新日期：1983-10-01 00:00:00

abstract：AIMS:To compare intratumorous microvessel density (MVD) and clinicopathological features in two different groups of hepatocellular carcinoma (HCC), namely: hepatitis B virus (HBV) related HCC (B-HCC) and HCV related HCC (C-HCC). METHODS:Fifty consecutive cases each of B-HCC and of C-HCC were studied. Microvessel numbe...

journal_title：Journal of clinical pathology

authors： Messerini L,Novelli L,Comin CE

更新日期：2004-08-01 00:00:00

abstract：AIMS:The chemokine receptor CXCR7 is found on glioma cells and glioma-associated vessels and dependent upon its localisation on tumour or endothelial cells the CXCR7 receptor can mediate glioma cell invasion and tumour angiogenesis. Its expression predicts survival in several types of cancers. METHODS:We immunohistoch...

journal_title：Journal of clinical pathology

authors： Birner P,Tchorbanov A,Natchev S,Tuettenberg J,Guentchev M

更新日期：2015-10-01 00:00:00

abstract：:The serotype of 320 strains of Proteus mirabilis from clinical material was determined. Using 20 O antisera and four H antisera 61% of strains could be fully identified and 90% partially identified. A large number of serotypes were recognized but no difference was found between the serotype of organisms infecting the ...

journal_title：Journal of clinical pathology

authors： De Louvois J

更新日期：1969-05-01 00:00:00

abstract：:The costs of a clinical chemistry laboratory in a district general hospital were studied. The system used has certain advantages over the conventional Cooper Lybrand method. The time taken by technicians to perform tests was more variable than expected and the cost of sample collection was higher than process-cost for...

journal_title：Journal of clinical pathology

authors： Stilwell JA

更新日期：1981-06-01 00:00:00