Perineural invasion predicts for locoregional failure in patients with oesophageal adenocarcinoma treated with neoadjuvant chemoradiotherapy.

abstract：:The Human Leukocyte Antigen (HLA) system plays a critical role in regulating the immune response. As a consequence of its role in immune regulation and exquisite polymorphism, the HLA system also constitutes an immunological barrier which must be avoided or otherwise overcome in clinical transplantation. This introduc...

journal_title：Journal of clinical pathology

authors： Howell WM,Carter V,Clark B

更新日期：2010-05-01 00:00:00

abstract：:The changes occurring at the periphery of invasive cervical carcinomas have been studied in detail, with particular reference to the incidence of preinvasive carcinoma. The various criteria used in the cytological diagnosis of malignancy have been evaluated, and the implications of large cytological screening programm...

journal_title：Journal of clinical pathology

authors： MEYER PC

更新日期：1965-07-01 00:00:00

abstract：AIMS/BACKGROUND:A major medical role for postmortem examinations is the detection of clinically unexpected disease processes contributing to death. The aim of the present study was to determine whether simple clinical parameters can predict the presence of important unanticipated findings at necropsy. METHODS:Prospect...

journal_title：Journal of clinical pathology

authors： Robinson IA,Marley NJ

更新日期：1996-11-01 00:00:00

abstract：:A latex agglutination test for the detection of Pseudomonas pseudomallei antigen in urine was evaluated for the rapid diagnosis of melioidosis. With unconcentrated urine, antigen was detected in only 18% of patients with melioidosis overall. However, when urine was concentrated 100-fold, antigen was detected in 47% ov...

journal_title：Journal of clinical pathology

authors： Smith MD,Wuthiekanun V,Walsh AL,Teerawattanasook N,Desakorn V,Suputtamongkol Y,Pitt TL,White NJ

更新日期：1995-02-01 00:00:00

abstract：:Experience gained in the last four years concerning the capabilities and limitations of an 8K Elliott 903 (18-bit word) computer with magnetic tape backing store in the routine operation of a clinical chemistry laboratory is described. Designed as a total system, routine operation has latterly had to be confined to da...

journal_title：Journal of clinical pathology

authors： Whitby LG,Simpson D

更新日期：1973-07-01 00:00:00

abstract：:Preoperative (neoadjuvant) chemoradiation therapy/treatment (NCRT) is emerging as an important treatment modality in borderline resectable pancreatic ductal adenocarcinoma (PDAC). The constellation of histopathological changes secondary to chemoradiation is diverse and has been well documented, particularly in other g...

journal_title：Journal of clinical pathology

authors： Kalimuthu SN,Serra S,Dhani N,Chetty R

更新日期：2016-06-01 00:00:00

abstract：:In the past decade, cellular immunophenotyping has become a new discipline in diagnostic haematology and immunology, and is invaluable in the rapid diagnosis of leukaemia and monitoring disease progression in human immunodeficiency virus infected individuals. The introduction of bench top flow cytometers has meant tha...

journal_title：Journal of clinical pathology

authors： Reilly JT,Barnett D

更新日期：2001-07-01 00:00:00

abstract：:Platelet adhesiveness has been measured in citrated whole blood and in platelet-rich plasma obtained from normal subjects, splenectomized patients, and from patients in whom the diagnosis of recurrent venous thrombosis had been made. The duration of centrifugation used in the preparation of platelet-rich plasma was fo...

journal_title：Journal of clinical pathology

authors： McBride JA

更新日期：1968-05-01 00:00:00

abstract：:Eight strains of Pseudomonas putrefaciens have been received from among 466 strains of Pseudomonas submitted to the Computer Trials Laboratory for identification over the last eight years. Two of the strains of P. putrefaciens from patients with otitis media and otitis externa respectively appear to have played a path...

journal_title：Journal of clinical pathology

authors： Holmes B,Lapage SP,Malnick H

更新日期：1975-02-01 00:00:00

abstract：:Three cases of islet cell necrosis in neonates are reported. The association of this rare condition with antepartum haemorrhage, anoxia, shock and intravascular coagulation are discussed. The clinical and morphological appearances were compared with previous descriptions of this condition and an association with neona...

journal_title：Journal of clinical pathology

authors： Roberts PF

更新日期：1987-10-01 00:00:00

abstract：AIMS:To investigate whether the use of recombinant early antigens for detection of antibodies to human cytomegalovirus (HCMV) gene products CM(2) (UL44, UL57) and p52 (UL44) is specific in the diagnosis and differentiation of active HCMV infection in a subset of patients with chronic fatigue syndrome (CFS), a diagnosis...

journal_title：Journal of clinical pathology

authors： Beqaj SH,Lerner AM,Fitzgerald JT

更新日期：2008-05-01 00:00:00

abstract：:Nasal biopsy findings in malignant histiocytosis presenting clinically as lethal midline granuloma are characterised by necrosis and infiltration of atypical histiocytic cells with a diffuse positive reaction for non-specific esterase. This cellular character was common to midline malignant reticulosis, and midline ma...

journal_title：Journal of clinical pathology

authors： Aozasa K

更新日期：1982-06-01 00:00:00

abstract：:In the present investigation, the prevalence of focal lymphocytic adenitis in the submandibular salivary gland was observed in a series of 116 postmortem subjects after suitable exclusions had been made. Focal lymphocytic adenitis could not be demonstrated in the labial salivary glands. The degree of lymphocytic infil...

journal_title：Journal of clinical pathology

authors： Chisholm DM,Waterhouse JP,Mason DK

更新日期：1970-11-01 00:00:00

abstract：AIMS:To isolate RNA and DNA simultaneously from formalin fixed paraffin wax embedded tissue to assess the clonality of enteropathy associated T cell lymphomas and to analyse it in detail by a non-radioactive method of T cell receptor complementarity determining region 3 (CDR3) spectratyping. METHODS:DNA and RNA were i...

journal_title：Journal of clinical pathology

authors： O'Shea U,Wyatt JI,Howdle PD

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND:Fibrinogen plays a crucial role in the pathophysiology of tumour cell growth, invasion and metastasis. The aim of this study was to evaluate the prognostic significance of pretreatment plasma fibrinogen levels in patients with diffuse large B cell lymphoma (DLBCL) METHODS: Data from 372 patients with DLBCL, ...

journal_title：Journal of clinical pathology

authors： Troppan KT,Melchardt T,Wenzl K,Schlick K,Deutsch A,Bullock MD,Reitz D,Beham-Schmid C,Weiss L,Neureiter D,Tränkenschuh W,Greil R,Neumeister P,Egle A,Pichler M

更新日期：2016-04-01 00:00:00

abstract：AIM:To evaluate the clinical usefulness of three commercially available assays for Her-2/neu oncogene and protein measurements. The Her-2/neu protein is overexpressed, mostly as a result of gene amplification, in 20-30% of human breast cancers, and has been shown to have prognostic and predictive value for treatment wi...

journal_title：Journal of clinical pathology

authors： Wang S,Saboorian MH,Frenkel E,Hynan L,Gokaslan ST,Ashfaq R

更新日期：2000-05-01 00:00:00

abstract：:The systematic screening of 253 children with transfusion-dependent homozygous beta-thalassaemia revealed a high incidence of hepatitis B virus markers. The highest frequencies of hepatitis B surface antigen (HBsAg) and antibody to hepatitis B core antigen (anti-HBc) were found in the group of patients with the smalle...

journal_title：Journal of clinical pathology

authors： De Virgiliis S,Fiorelli G,Fargion S,Cornacchia G,Sanna G,Cossu P,Murgia V,Cao A

更新日期：1980-10-01 00:00:00

abstract：AIM:Solid and papillary epithelial neoplasm (SPEN) is an uncommon pancreatic tumour. Very rarely it has also been described outside the pancreas, usually arising from heterotopic pancreatic tissue. This report summarises all the published extrapancreatic SPENs and documents the sixth such case arising from heterotopic ...

journal_title：Journal of clinical pathology

authors： Tornóczky T,Kálmán E,Jáksó P,Méhes G,Pajor L,Kajtár GG,Battyány I,Davidovics S,Sohail M,Krausz T

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND:Receptor activator of nuclear factor kappabeta ligand (RANKL) has an important role in bone remodelling, and tumour necrosis factor related, apoptosis inducing ligand (TRAIL) can induce apoptosis in cancer cells. Their functions are linked by their interactions with osteoprotegerin (OPG). OBJECTIVE:To inves...

journal_title：Journal of clinical pathology

authors： Cross SS,Harrison RF,Balasubramanian SP,Lippitt JM,Evans CA,Reed MW,Holen I

更新日期：2006-07-01 00:00:00

abstract：:Tubulocystic carcinoma (TCC) is a very rare renal tumour with unique gross and microscopic features, alternatively considered as low-grade collecting duct carcinoma. Recent studies favoured distinction of TCC from collecting duct carcinoma, and some cases of TCC synchronously coexisting with other renal cell tumour su...

journal_title：Journal of clinical pathology

authors： Chen N,Nie L,Gong J,Chen X,Xu M,Chen M,Zhou Q

更新日期：2014-11-01 00:00:00

abstract：:Visceral botryomycosis is rare, and documented sites are lung, brain, kidney, liver and prostate. This report describes a rare autopsy case of disseminated visceral botryomycosis, with bulky, grape-like botryomycotic vegetations in the heart, and similar abscesses in the lungs and bone marrow. This is the first such r...

journal_title：Journal of clinical pathology

authors： Gupta K,Das A,Radotra BD,Bhalla A

更新日期：2008-08-01 00:00:00

abstract：AIM:To determine the size of a cervical biopsy specimen with human papillomavirus (HPV) infection required to enable in situ hybridisation to be carried out with a guarantee of a reliable result. METHODS:In situ hybridisation was carried out in 142 cervical uterine biopsy specimens classified histologically as low gra...

journal_title：Journal of clinical pathology

authors： Gómez F,Corcuera MT,Muñoz E,Roldan M,Alonso MJ,Abad M,Paz JI,López-Bravo A

更新日期：1995-01-01 00:00:00

abstract：AIM:To examine peripheral blood and skeletal muscle from patients with chronic fatigue syndrome for exogenous retrovirus. METHODS:Blood samples from 30 patients and muscle biopsy specimens of 15 patients were examined for retroviral sequences by DNA extraction, polymerase chain reaction (PCR), and Southern blotting hy...

journal_title：Journal of clinical pathology

authors： Gow JW,Simpson K,Schliephake A,Behan WM,Morrison LJ,Cavanagh H,Rethwilm A,Behan PO

更新日期：1992-12-01 00:00:00

abstract：BACKGROUND:Autoreactive humoral and cellular immune responses may be involved in the pathogenesis of idiopathic dilated cardiomyopathy (IDC). Certain human leucocyte antigens (HLA) could also be linked to the development of IDC. AIM:To determine whether various markers of autoimmunity are present in the final phase of...

journal_title：Journal of clinical pathology

authors： de Leeuw N,Melchers WJ,Ruiter DJ,Caforio AL,Balk AH,de Jonge N,Galama JM

更新日期：1999-10-01 00:00:00

abstract：:Serum haptoglobin levels have been studied in patients with a number of haemolytic disorders. In general, serum haptoglobins were low in patients with increased haemolysis. Values were reduced irrespective of whether haemolysis occurred intravascularly or extravascularly. The reduction was related to the amount of hae...

journal_title：Journal of clinical pathology

authors： Owen JA,de Gruchy GC,Smith H

更新日期：1960-11-01 00:00:00

abstract：:A young woman presented with bilateral ovarian tumours. Multiple sections of each tumour were shown to many pathologists for consultation; some considered the tumours to be borderline, whereas others thought that one or both of them was malignant. Morphometry showed that the numerical classification probabilities for ...

journal_title：Journal of clinical pathology

authors： Baak JP,Van der Ley G

更新日期：1984-10-01 00:00:00

abstract：AIMS:To perform a clinicopathological analysis of a series of primary cutaneous Ewing sarcomas/primitive neuroectodermal tumours (ES/PNET) to highlight the pathological features, discuss the differential diagnosis, emphasise the role of molecular testing (particularly fluorescence in situ hybridisation, FISH) in diagno...

journal_title：Journal of clinical pathology

authors： Shingde MV,Buckland M,Busam KJ,McCarthy SW,Wilmott J,Thompson JF,Scolyer RA

更新日期：2009-10-01 00:00:00

abstract：:The activities of phosphohexose isomerase and 6-phosphogluconate dehydrogenase have been studied in the vaginal fluid of women from the gynaecological departments. Women from these departments gave a very high false positive rate, though no cases of carcinoma in situ were not detected by estimating phosphohexose isome...

journal_title：Journal of clinical pathology

authors： Muir GG

更新日期：1966-07-01 00:00:00

abstract：:In a case of atypical mucin-producing bronchial carcinoid in a 40-year-old man covert metastases were present at the time of lobectomy and were revealed at necropsy--a feature highlighting the malignant potential of the atypical carcinoid. ...

journal_title：Journal of clinical pathology

authors： Sweeney EC,Cooney T

更新日期：1978-12-01 00:00:00

abstract：AIMS:To investigate whether increasing the daily baseline of gut calcium can cause a gradual downregulation of the active intestinal transport of calcium via reduced parathyroid hormone (PTH) mediated activation of vitamin D, and to discuss why such a mechanism might prevent calcium oxalate rich stones. To demonstrate ...

journal_title：Journal of clinical pathology

authors： Williams CP,Child DF,Hudson PR,Davies GK,Davies MG,John R,Anandaram PS,De Bolla AR

更新日期：2001-01-01 00:00:00