Expression of 120 kilodalton protein and cytotoxicity in Helicobacter pylori.

Abstract:

:Antral biopsy culture supernatants from 14 subjects with chronic gastritis, known to have IgA antibodies to the 120 kilodalton protein, showed positive recognition of this antigen in western blots against a cytotoxin positive strain of Helicobacter pylori but gave negative reactions with two cytotoxin negative strains. Control immunoblots with culture supernatants from 13 non-responders to the protein were all negative. This indicates a direct association between expression of the 120 kilodalton protein in H pylori strains and cytotoxicity.

journal_name

J Clin Pathol

authors

Crabtree JE,Figura N,Taylor JD,Bugnoli M,Armellini D,Tompkins DS

doi

10.1136/jcp.45.8.733

keywords:

subject

Has Abstract

pub_date

1992-08-01 00:00:00

pages

733-4

issue

8

eissn

0021-9746

issn

1472-4146

journal_volume

45

pub_type

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