An evaluation of 12 methods for the demonstration of penicillinase.

abstract：:An immunohistochemical study of the tissue CEA content of 82 epithelial neoplasms of the ovary has shown that mucinous tumours contain more of this substance than do their serous counterparts; otherwise a knowledge of tissue CEA content appears to be of little value in the differential histological diagnosis of this g...

journal_title：Journal of clinical pathology

authors： Heald J,Buckley CH,Fox H

更新日期：1979-09-01 00:00:00

abstract：INTRODUCTION:Cellular blue naevi (CBN) measure 1-2 cm in diameter and affect the dermis, occasionally extending into the subcutaneous fat. The case of a 14-year-old boy with a giant CBN (GCBN) involving the right half of the face, the jugal mucosa and the lower eyelid with a tumour that had infiltrated the bone and the...

journal_title：Journal of clinical pathology

authors： Bittencourt AL,Monteiro DA,De Pretto OJ

更新日期：2007-01-01 00:00:00

abstract：:Laboratory studies on clotrimazole showed that it had marked activity in vitro against all the Candida spp. and Cryptococcus spp. tested, against almost all strains of dermatophytes, and against Aspergillus spp and other fungal genera responsible for systemic mycoses; it had limited activity towards Gram-positive bact...

journal_title：Journal of clinical pathology

authors： Holt RJ,Newman RL

更新日期：1972-12-01 00:00:00

abstract：BACKGROUND:Venous invasion (VI) is an important prognosis predictor after colorectal carcinoma (CRC) resection, enabling more accurate staging and influencing postoperative management. AIMS:To assess/compare various tissue block types (perpendicular, tangential, across mesentery (AM), from major vessels or lymph nodes...

journal_title：Journal of clinical pathology

authors： Sternberg A,Mizrahi A,Amar M,Groisman G

更新日期：2006-02-01 00:00:00

abstract：:Incomplete expression of human haemoglobin beta-chains at birth may lead to difficulty in the early demonstration of an inherited beta-chain variant. In this case, the rare unstable variant, Hb Tacoma beta30 (B12) arg leads to ser, although not present in cord blood in sufficient amounts to be easily detected by routi...

journal_title：Journal of clinical pathology

authors： Deacon-Smith RA,Lee-Potter JP

更新日期：1978-09-01 00:00:00

abstract：:The routine estimation of large numbers of serum folic acid and vitamin B(12) levels using the Baird and Tatlock(1) Analmatic clinical system is described and the method evaluated.Precision, accuracy, and carryover are shown to be at acceptable levels, and the advantages and disadvantages of the use of the system are ...

journal_title：Journal of clinical pathology

authors： Colvin G,Gibson GL,Neill DW

更新日期：1971-02-01 00:00:00

abstract：:This article reviews recent information concerning the origin of osteoclasts and the local and systemic regulation of their activity. It appears that much of the environmental responsiveness of osteoclasts is mediated by cells of the osteoblastic lineage, which exert a major influence on the localisation, induction, s...

journal_title：Journal of clinical pathology

authors： Chambers TJ

更新日期：1985-03-01 00:00:00

abstract：AIMS:Our laboratory is a centralised centre receiving routine non-small cell lung cancer (NSCLC) samples for programmed death ligand-1 (PD-L1) immunohistochemical (IHC) evaluation. Since literature data are not concordant here we review our clinical records to assess the rate of PD-L1 positive and negative NSCLC cases ...

journal_title：Journal of clinical pathology

authors： Vigliar E,Malapelle U,Iaccarino A,Acanfora G,Pisapia P,Clery E,De Luca C,Bellevicine C,Troncone G

更新日期：2019-06-01 00:00:00

abstract：AIMS:The probabilistic approach is widely adopted for breast fine needle aspiration cytology. However, a definite cytological diagnosis is not always possible for C3 (atypia) cases, which poses a management dilemma as this represents a mixed category of benign and malignant cases. It would be beneficial to be able to p...

journal_title：Journal of clinical pathology

authors： Yu SN,Li J,Wong SI,Tsang JYS,Ni YB,Chen J,Tse GM

更新日期：2017-12-01 00:00:00

abstract：:Endocardial fibroelastosis, defined as an endocardium in excess of 30 microns thick, was found in 10 out of 34 cases of hydrops fetalis in a review of 1589 perinatal necropsies carried out between 1976 and 1989. The infants comprised 16 cases of rhesus haemolytic disease, of whom three had endocardial fibroelastosis, ...

journal_title：Journal of clinical pathology

authors： Newbould MJ,Armstrong GR,Barson AJ

更新日期：1991-07-01 00:00:00

abstract：:The prevalence of lymphoid follicles in endoscopic biopsy specimens from normal antral mucosa (n = 220), mucosa with reflux gastritis (n = 104), and in cases with Campylobacter pylori-associated gastritis (n = 2544) was studied. In the latter group whether there were associations between degree and activity of gastrit...

journal_title：Journal of clinical pathology

authors： Stolte M,Eidt S

更新日期：1989-12-01 00:00:00

abstract：:The immunofluorescent examination of nasopharyngeal secretions has been compared with conventional cell culture for the diagnosis of respiratory syncytial (RS) virus infection in children under the age of 2 years in Newcastle upon Tyne and Manchester. Two hundred and sixty-eight identifications of RS virus were made b...

journal_title：Journal of clinical pathology

authors： Cradock-Watson JE,McQuillin J,Gardner PS

更新日期：1971-05-01 00:00:00

abstract：AIMS:To study the homozygous deletion and methylation status of the 5' CpG island of the p16 and p15 genes (9p21) in a set of primary advanced head and neck squamous cell carcinomas (SCC) and to test whether inactivation of these genes by these mechanisms contributes to head and neck SCC development. METHODS:DNA was e...

journal_title：Journal of clinical pathology

authors： González MV,Pello MF,López-Larrea C,Suárez C,Menéndez MJ,Coto E

更新日期：1997-06-01 00:00:00

abstract：BACKGROUND:In primary cutaneous melanoma, the sentinel node (SN) biopsy is an accurate method for the staging of the lymph nodes. Positron emission tomography (PET) has been suggested as a useful alternative. However, the sensitivity of PET may be too low to detect SN metastases, which are often small. AIM:To predict ...

journal_title：Journal of clinical pathology

authors： Mijnhout GS,Hoekstra OS,van Lingen A,van Diest PJ,Adèr HJ,Lammertsma AA,Pijpers R,Meijer S,Teule GJ

更新日期：2003-04-01 00:00:00

abstract：:A time and temperature relationship required to destroy certain pathogenic organisms in milk feeds has been ascertained. A method of achieving this destruction by using steam at atmospheric pressure is described, and a routine method for use in milk kitchens is suggested. ...

journal_title：Journal of clinical pathology

authors： Hughes KE,Darmady EM,Drewett SE

更新日期：1966-07-01 00:00:00

abstract：:Cryostat sections from 160 rectal suction biopsies were stained for cholinesterases by the method of Karnovsky and Roots (1964) in an attempt to facilitate the diagnosis of Hirschsprung's disease. The method proved at least as reliable as experienced assessment of paraffin haematoxylin-eosin sections, and appeared to ...

journal_title：Journal of clinical pathology

authors： Trigg PH,Belin R,Haberkorn S,Long WJ,Nixon HH,Plaschkes J,Spitz L,Willital GH

更新日期：1974-03-01 00:00:00

abstract：:This paper illustrates a simple method of necropsy dissection of the abdominal organs after abdominal surgery. The organs are removed in one block as per the method described by Letulle. A retroperitoneal approach is then used. Structures are dissected away in a series of layers using the vasculature for guidance. Thi...

journal_title：Journal of clinical pathology

authors： Culora GA,Roche WR

更新日期：1996-09-01 00:00:00

abstract：:Acute myocardial disease, which may be associated with abnormal platelet activity, has been reported after routine immunisation. Thirty-two army apprentices undergoing immunisation were studied for changes in the heparin neutralising activity (HNA) of platelet poor plasma. HNA increased after immunisation. This increa...

journal_title：Journal of clinical pathology

authors： Baker IA,Howells CH,O'Brien JR

更新日期：1979-11-01 00:00:00

abstract：AIMS:The assessment of lymphatic vessel density (LVD) has been suggested as a tool to determine the metastatic risk of neoplasias. On this premise, the authors aimed to verify whether progression risk of stage I colorectal cancer may be related to LVD. The authors also evaluated and correlated vascular endothelial grow...

journal_title：Journal of clinical pathology

authors： Barresi V,Reggiani-Bonetti L,Di Gregorio C,De Leon MP,Barresi G

更新日期：2011-01-01 00:00:00

abstract：:Thirteen meningiomas of varying light microscopic features were studied immunohistologically using a panel of monoclonal antibodies directed against epithelial, mesenchymal, and neural components. All 13 meningiomas showed expression of epithelial membrane antigen, vimentin, and S100 protein, as did normal meninges. F...

journal_title：Journal of clinical pathology

authors： Theaker JM,Gatter KC,Esiri MM,Fleming KA

更新日期：1986-04-01 00:00:00

abstract：:Using a short series of biochemical tests already in use in many routine laboratories, it is possible to identify strains of the genus Klebsiella and to differentiate K. aerogenes from other types. Marked production of slime is not peculiar to the group and colonial appearance alone is not a satisfactory basis for ide...

journal_title：Journal of clinical pathology

authors： DARRELL JH,HURDLE AD

更新日期：1964-11-01 00:00:00

abstract：AIM:To develop a unified diagnostic approach for the detection of human papillomavirus (HPV) DNA in skin and mucosal biopsies from both immunocompetent and immunosuppressed individuals using a degenerate polymerase chain reaction (PCR) method. METHODS:The sensitivity and specificity of three published degenerate prime...

journal_title：Journal of clinical pathology

authors： Surentheran T,Harwood CA,Spink PJ,Sinclair AL,Leigh IM,Proby CM,McGregor JM,Breuer J

更新日期：1998-08-01 00:00:00

abstract：:This review focuses on the pathological features of dysplasia in Barrett's oesophagus. Two categorisation schemes are used for grading dysplasia in the gastrointestinal tract, including Barrett's oesophagus. The inflammatory bowel disease dysplasia morphology study group system is the one most commonly used in the USA...

journal_title：Journal of clinical pathology

authors： Odze RD

更新日期：2006-10-01 00:00:00

abstract：:Histological assessment of melanocytic naevi constitutes a substantial proportion of a dermatopathologist's daily workload. Although they may be excised for cosmetic reasons, most lesions encountered are clinically atypical and are biopsied or excised to exclude melanoma. Although dysplastic naevi are most often encou...

journal_title：Journal of clinical pathology

authors： Culpepper KS,Granter SR,McKee PH

更新日期：2004-11-01 00:00:00

abstract：:Sera can produce nuclear or perinuclear immunofluorescence staining in neutrophils which may be caused by antibodies with differing antigenic specificities. These include perinuclear antineutrophil cytoplasmic antibodies (P-ANCA), granulocyte specific antinuclear antibody (GS-ANA), and antinuclear antibody (ANA). Ther...

journal_title：Journal of clinical pathology

authors： Chowdhury SM,Broomhead V,Spickett GP,Wilkinson R

更新日期：1999-06-01 00:00:00

abstract：:Rosetting and non-rosetting lymphocytes collected from normal individuals were stained for the presence of beta-glucuronidase, periodic-acid Schiff activity, gamma glutamyl transpeptidase, acid phosphatase, and alpha-naphthyl butyrate esterase. Lymphocytes which formed rosettes with sheep erythrocytes and non-rosette ...

journal_title：Journal of clinical pathology

authors： Davey FR,Huntington SJ,Maccallum J,Macmath JM

更新日期：1977-07-01 00:00:00

abstract：:The plasma concentrations of biotin were measured for up to 49 days after injury in nine children with burns and scalds which involved from 12% to 50% of the surface area of the body. Biotin levels below the minimum of the control range were observed in eight of the nine injured children at some stage during the episo...

journal_title：Journal of clinical pathology

authors： Barlow GB,Dickerson JA,Wilkinson AW

更新日期：1976-01-01 00:00:00

abstract：:A 60 year old woman with disseminated ductal carcinoma of the breast developed non-islet cell tumour induced hypoglycaemia (NICTH). The concentrations of the two insulin-like growth factors, IGF-I and IGF-II, were < 2 nmol/l and 94.1 nmol/l, respectively. The IGF-II to IGF-I ratio was > 47 (normal < 10). Insulin (< 3 ...

journal_title：Journal of clinical pathology

authors： Bessell EM,Selby C,Ellis IO

更新日期：1999-10-01 00:00:00

abstract：:The finding of raised growth hormone concentrations in patients with secondary malignancy in the liver is reported. These concentrations were significantly higher than those found in patients with primary malignancy only or in those with non-hepatic secondaries. A wide range of malignancies was investigated and the hi...

journal_title：Journal of clinical pathology

authors： Andrews GS

更新日期：1983-08-01 00:00:00

abstract：:A method is described for the quantitative separation of radioactive bile acids and neutral sterols in human faeces on a potassium hydroxide-treated silicic acid column. Results obtained with faecal extracts containing metabolites derived from radioactive cholesterol, cholic acid, and chenodeoxycholic acid show that t...

journal_title：Journal of clinical pathology

authors： LEWIS B,MYANT NB

更新日期：1965-01-01 00:00:00