Topoisomerase II alpha mRNA and tumour cell proliferation in non-Hodgkin's lymphoma.

abstract：AIMS:To investigate the histopathological changes in the livers of patients undergoing cholecystectomy and to relate these changes to the underlying biliary tract pathology. METHODS:Liver changes in 67 patients undergoing cholecystectomy were investigated. Sixty three had gall stones, one cholesterolosis only, and the...

journal_title：Journal of clinical pathology

authors： Geraghty JM,Goldin RD

更新日期：1994-05-01 00:00:00

abstract：:Sperm-agglutinating antibodies were present in three (2-6%) of 117 fertile men and in 19 (33-9%) of 56 men who had been vasectomized. Twenty-four of the 56 vasectomized men had been studied before vasectomy; sperm-agglutinating antibodies were present in one (4-3%) compared with eight (33-3%) after vasectomy. No sperm...

journal_title：Journal of clinical pathology

authors： Hunter J,Logan H,Greer G

更新日期：1976-12-01 00:00:00

abstract：AIMS:To determine the possible histogenesis of the intracranial variant of olfactory neuroblastoma. METHODS:Four specimens from three cases of intracranial olfactory neuroblastoma were studied by light microscopy and immuno-histochemistry, and electron microscopy in two cases. RESULTS:Light microscopical examination ...

journal_title：Journal of clinical pathology

authors： Banerjee AK,Sharma BS,Vashista RK,Kak VK

更新日期：1992-04-01 00:00:00

abstract：:The potencies of six commercially manufactured heparins have been measured by the British Pharmacopoeial (BP) assay and activated partial thromboplastin time (APTT), protamine sulphate, and anti-Xa assays. The APTT/BP potency ratios were found to vary with the preparation but this was not dependent on the tissue sourc...

journal_title：Journal of clinical pathology

authors： Shah GA,Dhall TZ,Ferguson I,Davis MR,Graham DT,Pomeroy AR,Dhall DP

更新日期：1980-06-01 00:00:00

abstract：AIMS:To evaluate the effect of 10 day triple treatment on H pylori eradication and associated gastritis. METHODS:Fifty patients with H pylori positive non-ulcer dyspepsia were treated for 10 days with amoxicillin, tinidazole, and bismuth salts. Histological examination of the antral mucosa was performed before (T0), s...

journal_title：Journal of clinical pathology

authors： Di Napoli A,Petrino R,Boero M,Bellis D,Chiandussi L

更新日期：1992-09-01 00:00:00

abstract：:Cervical smears from 327 women were examined using the polymerase chain reaction (PCR) targeted to a sequence in the Bam H1 W region of the Epstein-Barr virus (EBV) to determine the prevalence of the virus in the cervix. EBV was detected in 131 (40%) of the 327 women. Of the 235 women with normal cytology, 98 (42%) we...

journal_title：Journal of clinical pathology

authors： Taylor Y,Melvin WT,Sewell HF,Flannelly G,Walker F

更新日期：1994-01-01 00:00:00

abstract：:Twelve methods for the demonstration of bacterial penicillinase production by strains of Haemophilus influenzae and Staphylococcus aureus are compared, and their suitability for routine clinical laboratory use is evaluated. The acidometric agar plate method is recommended. ...

journal_title：Journal of clinical pathology

authors： Lucas TJ

更新日期：1979-10-01 00:00:00

abstract：:Experiments are described with glass fibre filter paper and complete glass filters as fitted to high pre-vacuum autoclaves to determine whether organisms can grow or penetrate through the filters. A filter consisting of four layers of glass fibre paper fitted inside a sterilizer chamber for a year and used for 96 ster...

journal_title：Journal of clinical pathology

authors： Fallon RJ

更新日期：1963-05-01 00:00:00

abstract：:A biochemical typing method is described for Klebsiella pneumoniae (sensu lato) and Enterobacter aerogenes. The technique depends on differences in metabolism of five carbon substrates--glycerol, inositol, lactose, glucose, and xylose--at two concentrations. Reproducibility is satisfactory and is monitored by the inco...

journal_title：Journal of clinical pathology

authors： Barr JG,Hogg GM

更新日期：1979-09-01 00:00:00

abstract：:Strokes are one of the most common causes of mortality and long term severe disability. There is evidence that lipoprotein (a) (Lp(a)) is a predictor of many forms of vascular disease, including premature coronary artery disease. Several studies have also evaluated the association between Lp(a) and ischaemic (thrombot...

journal_title：Journal of clinical pathology

authors： Milionis HJ,Winder AF,Mikhailidis DP

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:The Sysmex XN haematology instrument performs automatic reflex testing, depending on sample results. A nucleated red blood cell (NRBC) count is provided on all samples. The instrument has a smaller footprint (34%) than previous Sysmex XE analysers. METHODS:An evaluation comparing all results to the Sysmex X...

journal_title：Journal of clinical pathology

authors： Briggs C,Longair I,Kumar P,Singh D,Machin SJ

更新日期：2012-11-01 00:00:00

abstract：:VARIOUS LABORATORIES HAVE REPORTED DIFFERING SUCCESS RATES IN THEIR ABILITY TO DETECT INTRATHECAL SYNTHESIS OF ANTIBODY WHEN COMPARING THE INDEX OF [FORMULA: see text] with electrophoretic analysis. We selected 44 patients in the borderline area of minimal and/or equivocal abnormality by IgG index. Electrophoretic ana...

journal_title：Journal of clinical pathology

authors： Thompson EJ,Riches PG,Kohn J

更新日期：1983-03-01 00:00:00

abstract：:A radioimmunoassay for the measurement of gonadotrophin releasing hormone (GnRH) in plasma and urine using readily available reagents was developed. The GnRH assay showed good precision, recovery, and parallelism over a wide range of GnRH concentrations with a sensitivity of 15 pg/ml. The assay was compared with a com...

journal_title：Journal of clinical pathology

authors： Mosby VA,Knapp ML,Fink RS,Osgood VM,Mayne PD

更新日期：1989-05-01 00:00:00

abstract：:A saccharogenic method is described for estimating amylase activity in human urine. Results accord with those reported elsewhere except that in this study the peak in the beta zone is a new finding. Comparison between normal and pathological urines suggests that the amylase activity of the beta peak is not of pancreat...

journal_title：Journal of clinical pathology

authors： Franzini C

更新日期：1965-09-01 00:00:00

abstract：:A miniaturised method for the identification of anaerobic bacteria is described which employs microtitre fermentation tests, a spot indole test and a nitrate reduction disc test. The results obtained are directly comparable with those produced by a standard conventional method in use at present. ...

journal_title：Journal of clinical pathology

authors： Levett PN

更新日期：1984-01-01 00:00:00

abstract：AIMS:Marked thrombocytosis is uncommon in chronic myelogenous leukaemia (CML) but may be associated with mutation of JAK2 V617F, calreticulin (CALR) and/or phospho-STAT5 (p-STAT5) activation in other myeloproliferative neoplasms (MPNs), particularly essential thrombocythaemia (ET). We investigated the JAK2 V617F, CALR ...

journal_title：Journal of clinical pathology

authors： Turakhia SK,Murugesan G,Cotta CV,Theil KS

更新日期：2016-08-01 00:00:00

abstract：:Five cases of inflammatory pseudotumour of the liver are reported and compared with seven individual previously published case reports. Clinical presentation was variable but often comprised low grade intermittent fever, vague abdominal symptoms, and a history of weight loss. Leucocytosis, raised erythrocyte sedimenta...

journal_title：Journal of clinical pathology

authors： Anthony PP,Telesinghe PU

更新日期：1986-07-01 00:00:00

abstract：:Tests of iron and folate nutrition have been carried out in early pregnancy and at delivery in 63 Bantu females. Accepted normal values for serum iron, and percentage saturation of transferrin, but not for unsaturated iron-binding capacity, for non-pregnant subjects were found to apply equally well in pregnancy. Conco...

journal_title：Journal of clinical pathology

authors： Metz J,Turchetti L,Combrink B,Krawitz S

更新日期：1966-03-01 00:00:00

abstract：:Sera can produce nuclear or perinuclear immunofluorescence staining in neutrophils which may be caused by antibodies with differing antigenic specificities. These include perinuclear antineutrophil cytoplasmic antibodies (P-ANCA), granulocyte specific antinuclear antibody (GS-ANA), and antinuclear antibody (ANA). Ther...

journal_title：Journal of clinical pathology

authors： Chowdhury SM,Broomhead V,Spickett GP,Wilkinson R

更新日期：1999-06-01 00:00:00

abstract：:By means of enzyme immunoassays based on two monoclonal antibodies with specificities for distinct forms of placental type alkaline phosphatase (Pl-ALP), together with L-leucine inhibition studies, it has been possible to distinguish the Nagao type carcinoplacental enzyme from other placental type alkaline phosphatase...

journal_title：Journal of clinical pathology

authors： McLaughlin PJ,Twist AM,Evans CC,Johnson PM

更新日期：1984-07-01 00:00:00

abstract：BACKGROUND:Fungal infection is increasingly recognised as an important cause of morbidity and mortality, especially in immunocompromised patients. Little information exists on laboratory services available and the methods used by general microbiology laboratories to diagnose these important infections. AIM:To investig...

journal_title：Journal of clinical pathology

authors： Hassan IA,Critten P,Isalska B,Denning DW

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:Thyrotropin-secreting adenomas (TSH-As) are rare and, according to the World Health Organization criteria (WHO 2004), a significant proportion of them present features of atypical adenomas at the time of diagnosis. AIMS:To determine the frequency of "atypical adenomas" and the significance of this definitio...

journal_title：Journal of clinical pathology

authors： Marucci G,Faustini-Fustini M,Righi A,Pasquini E,Frank G,Agati R,Foschini MP

更新日期：2009-05-01 00:00:00

abstract：AIMS:Epidermal growth factor receptor (EGFR) T790M mutations can be detected in the circulating tumour DNA from plasma of patients with non-small cell lung cancer (NSCLC) to triage patients for osimertinib eligibility and monitor patients longitudinally for development of T790M-mediated resistance. METHODS:Using dropl...

journal_title：Journal of clinical pathology

authors： Spence T,Perera S,Weiss J,Grenier S,Ranich L,Shepherd F,Stockley TL

更新日期：2021-02-01 00:00:00

abstract：:Surface immunoglobulins (Ig) of normal and malignant lymphoid cells were detected on prefixed, smeared (method A) and live (method B) cell suspensions; the results were compared with regard to staining patterns, specificity and sensitivity. In both methods surface Ig were detected by a direct immunoperoxidase procedur...

journal_title：Journal of clinical pathology

authors： Laurent G,Gourdin MF,Reyes F

更新日期：1982-02-01 00:00:00

abstract：:This review of the histomorphometry of bone outlines methods of biopsy and processing of specimens in the laboratory, the basic principles of morphometry, and the measurements made in order to obtain estimates of the proportional volumes and surfaces occupied by different components of bone. Variability such as that b...

journal_title：Journal of clinical pathology

authors： Revell PA

更新日期：1983-12-01 00:00:00

abstract：:The rate of digestion of fibrin was measured in vitro by an isotopic technique in 140 blood samples of differing fibrinogen concentration; the assessment of fibrinolytic activity thus obtained was compared with a standard method of measurement, the dilute whole blood lysis time. The lysis time was related exponentiall...

journal_title：Journal of clinical pathology

authors： Hickman JA,Gordon-Smith IC,Whitfield PF,Godfrey SJ

更新日期：1973-03-01 00:00:00

abstract：:A patient with chronic granulomatous disease who was being treated with steroids was diagnosed with a soft tissue Scedosporium apiospermum infection. Despite extensive treatment with antifungals progression to involve solid tissue (bone) occurred. Treatment required an HLA matched bone marrow transplant, which led to ...

journal_title：Journal of clinical pathology

authors： Gompels MM,Bethune CA,Jackson G,Spickett GP

更新日期：2002-10-01 00:00:00

abstract：:Hereditary spherocytosis is a relatively common haematological disorder and will be encountered by all haematologists. The abundance of new information, dealing principally with molecular and genetic aspects of pathophysiology, is beginning to have implications for its investigation and management. While these advance...

journal_title：Journal of clinical pathology

authors： Smedley JC,Bellingham AJ

更新日期：1991-06-01 00:00:00

abstract：:A middle aged man developed very high fever, status epilepticus, and terminal acute renal failure with myoglobinuria after surgery. A post mortem examination showed widespread muscle necrosis with hypercontraction bands. Muscle enzyme studies and electron microscopic examination disclosed central core disease, a condi...

journal_title：Journal of clinical pathology

authors： Prescott RJ,Roberts SP,Williams G

更新日期：1992-04-01 00:00:00

abstract：:Two groups of women with non-specific genital infection were treated for two weeks with tetracycline 250 mg six-hourly and minocycline 100 mg twice daily respectively. Cultures for yeasts were performed before treatment and at the end of the first and second weeks. Before treatment yeasts, mostly Candida albicans, wer...

journal_title：Journal of clinical pathology

authors： Oriel JD,Waterworth PM

更新日期：1975-05-01 00:00:00