Site distribution of oesophagogastric cancer.

Abstract:

AIMS:It has been suggested that adenocarcinomas of the lower oesophagus and gastric cardia should be reclassified as oesophagogastric junction (OGJ) cancers. This study aimed to define the frequency of OGJ cancers in a geographically defined population of 4.3 million people. METHODS:All cases of oesophageal and gastric cancer occurring in 1993 were identified by the North Western Regional Cancer Registry. A total of 1192 hospital case notes were reviewed and a study group of 1067 patients was defined. Tumour involvement was documented at individual subsites in the oesophagus and stomach, allowing for tumour presence in more than one oesophageal/gastric subsite. RESULTS:There were 627 tumours in men and 440 in women. The tumour was confined to the oesophagus in 281 (26.3%) cases and to the stomach in 454 (42.6%) cases. The tumour encroached upon or crossed the OGJ in 332 (31.1%) cases. Overall, tumours involved the cardia, OGJ, or lower oesophagus in 633 (59.3%) cases; in 179 (18.5%) cases the tumour involved the lower oesophagus but not the OGJ, and in another 122 (11.4%) cases the cardia was involved but not the OGJ. CONCLUSIONS:Oesophagogastric cancers in this population predominantly involve the OGJ, lower oesophagus, and/or cardia.

journal_name

J Clin Pathol

authors

Byrne JP,Mathers JM,Parry JM,Attwood SE,Bancewicz J,Woodman CB

doi

10.1136/jcp.55.3.191

keywords:

subject

Has Abstract

pub_date

2002-03-01 00:00:00

pages

191-4

issue

3

eissn

0021-9746

issn

1472-4146

journal_volume

55

pub_type

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