A haemagglutination test for anti-Panton-Valentine leucocidin in serum: an interim report on 200 cases.

abstract：AIMS:To investigate how the biopsy Gleason score (GS) and the clinical risk classification have been changed by the reporting rules. METHODS:565 prostate biopsy specimens were reassessed. Each Gleason pattern, 1 to 5, was interpreted according to the modified Gleason grading system proposed by the International Societ...

journal_title：Journal of clinical pathology

authors： Kuroiwa K,Uchino H,Yokomizo A,Naito S

更新日期：2009-03-01 00:00:00

abstract：AIMS:To investigate the occurrence of abnormal patterns of HLA-ABC and HLA-DR expression in enteropathy associated T cell lymphoma and to relate such abnormalities to the Epstein Barr virus (EBV) status of the tumours. METHODS:Eleven enteropathy associated T cell lymphomas were immunostained with HC10 (HLA-ABC heavy c...

journal_title：Journal of clinical pathology

authors： Ashton-Key M,Singh N,Pan LX,Smith ME

更新日期：1996-07-01 00:00:00

abstract：AIMS:Acute traumatic coagulopathy is characterised by fibrinolysis and low fibrinogen. It is unclear how much fibrinogenolysis contributes to reduce fibrinogen levels. The study aim was to: investigate in vitro the effects of tissue-plasminogen activator (t-PA) and tranexamic acid (TXA) on coagulation and fibrinolysis....

journal_title：Journal of clinical pathology

authors： Godier A,Parmar K,Manandhar K,Hunt BJ

更新日期：2017-02-01 00:00:00

abstract：:Cutaneous melanoma causes most of the skin cancer deaths in the USA. Melanoma is the fifth most common cancer among men and the sixth most common cancer among women. The incidence of melanoma has risen sharply over the past three decades. In this review, which is informed by our extensive experience at a large cancer ...

journal_title：Journal of clinical pathology

authors： Trinidad CM,Torres-Cabala CA,Curry JL,Prieto VG,Aung PP

更新日期：2019-04-01 00:00:00

abstract：:Formalin fixation followed by routine paraffin embedding allows the demonstration of intracellular immunoglobulin by a sandwich technique using either peroxidase or fluorescein isothyocyanate labelled antibody conjugates. The results compared favourably with those obtained using either the fresh frozen or the Sainte-M...

journal_title：Journal of clinical pathology

authors： Burns J,Hambridge M,Taylor CR

更新日期：1974-07-01 00:00:00

abstract：BACKGROUND:During the last decade, whole slide images (WSI) have been used in many areas of pathology such as teaching, research, digital archiving, teleconsultation and quality assurance testing. However, WSI have not regularly been used for routine diagnosis, because of the lack of validation studies. AIM:To test th...

journal_title：Journal of clinical pathology

authors： Al-Janabi S,Huisman A,Vink A,Leguit RJ,Offerhaus GJ,Ten Kate FJ,van Dijk MR,van Diest PJ

更新日期：2012-02-01 00:00:00

abstract：:This report describes a case of myelofibrosis presenting as spinal cord compression on account of extramedullary haemopoietic tissue encroaching upon the spinal cord from a large pelvic mass. ...

journal_title：Journal of clinical pathology

authors： Horwood E,Dowson H,Gupta R,Kaczmarski R,Williamson M

更新日期：2003-02-01 00:00:00

abstract：AIMS:The WHO classification describes that combined hepatocellular-cholangiocarcinoma, subtypes with stem-cell features, intermediate-cell subtype (CHC-INT) is composed of tumour cells with features intermediate between hepatocytes and cholangiocytes. However, we previously reported that CHC-INT showed a high positive ...

journal_title：Journal of clinical pathology

authors： Akiba J,Nakashima O,Hattori S,Naito Y,Kusano H,Kondo R,Nakayama M,Tanikawa K,Todoroki K,Umeno Y,Nakamura K,Sanada S,Yamaguchi R,Ogasawara S,Yano H

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Hsulf-1 is a newly identified enzyme with arylsulphatase activity that can regulate the sulphation state of cell-surface heparan sulphate proteoglycans (HSPGs). In vitro overexpression of this enzyme in pancreatic cancer cells decreases responsiveness to fibroblastic growth factor-2, as Hsulf-1 is up regulat...

journal_title：Journal of clinical pathology

authors： Abiatari I,Kleeff J,Li J,Felix K,Büchler MW,Friess H

更新日期：2006-10-01 00:00:00

abstract：AIMS:To evaluate whether endometrial pathology is more likely to be diagnosed in gynaecologically symptomatic rather than in gynaecologically asymptomatic postmenopausal breast cancer patients with tamoxifen treatment; and to evaluate the possible influence of various clinical factors on the incidence of endometrial pa...

journal_title：Journal of clinical pathology

authors： Cohen I,Perel E,Flex D,Tepper R,Altaras MM,Cordoba M,Beyth Y

更新日期：1999-04-01 00:00:00

abstract：:This paper urges the benefits of applying more widely a method for pathology laboratory costing originally devised for a clinical chemistry department, and illustrates these with examples drawn from costing studies in three clinical laboratories. Heads of pathology departments, laboratory managers, administrators and ...

journal_title：Journal of clinical pathology

authors： Broughton PM,Woodford FP

更新日期：1983-09-01 00:00:00

abstract：BACKGROUND:Raised plasma ferritin concentrations occur unexpectedly during iron studies done by primary care physicians. Plasma ferritin concentration has been positively associated with alcohol use among men. AIM:To determine the post-test probability that men in the community with raised plasma ferritin concentratio...

journal_title：Journal of clinical pathology

authors： Peach HG,Bath NE

更新日期：1999-11-01 00:00:00

abstract：:Results of serological investigations on patients with joint pain, arthralgia or polyarthritis were analysed and this information was used to develop a diagnostic algorithm to ensure optimal utilisation of laboratory resources. Accordingly, all cases are now examined for parvovirus IgM, mycoplasma IgM and streptococca...

journal_title：Journal of clinical pathology

authors： Jones JW,Pether JV,Frost RW

更新日期：1995-08-01 00:00:00

abstract：:The sensitivity patterns to a number of antibiotic-impregnated discs of 126 strains of Gram-negative anaerobes and 36 strains of Gram-positive non-sporing anaerobes from various sources have been examined. The sensitivity patterns shown by Bacteroids fragilis and Bacteroides melaninogenicus were useful for the rapid i...

journal_title：Journal of clinical pathology

authors： Peach S

更新日期：1975-05-01 00:00:00

abstract：:A rapidly fatal case of enteritis necroticans in a 24 year old man with diabetes was caused by Clostridium perfringens type C. The role of beta toxin in the disease is discussed. This type has not been previously described as a causative agent in necrotising bowel disease of man outside endemic areas. ...

journal_title：Journal of clinical pathology

authors： Severin WP,de la Fuente AA,Stringer MF

更新日期：1984-08-01 00:00:00

abstract：AIMS:Periductal angiogenesis in ductal carcinoma in situ is associated with an increased risk of subsequently developing a recurrence. This study aimed to (1) identify the relation between periductal and stromal vascularity and recurrence and (2) determine whether thymidine phosphorylase (TP) is associated with angioge...

journal_title：Journal of clinical pathology

authors： Teo NB,Shoker BS,Jarvis C,Sloane JP,Holcombe C

更新日期：2003-12-01 00:00:00

abstract：:Incomplete expression of human haemoglobin beta-chains at birth may lead to difficulty in the early demonstration of an inherited beta-chain variant. In this case, the rare unstable variant, Hb Tacoma beta30 (B12) arg leads to ser, although not present in cord blood in sufficient amounts to be easily detected by routi...

journal_title：Journal of clinical pathology

authors： Deacon-Smith RA,Lee-Potter JP

更新日期：1978-09-01 00:00:00

abstract：:Serial dilutions of Clostridium difficile culture filtrates were incubated overnight with HeLa cell monolayers. Cells were fixed in formalin, stained with crystal violet, rinsed, and drained. Cell rounding could be observed microscopically in the stained monolayers. Absorbance of the retained dye on monolayers in the ...

journal_title：Journal of clinical pathology

authors： Rothman SW

更新日期：1986-06-01 00:00:00

abstract：:A radial immunodiffusion technique has been used to measure levels of four serum proteins in preeclampsia with or without proteinuria and in normal pregnant and non-pregnant controls. In preeclampsia unaccompanied by proteinuria, albumin and transferrin levels are similar to those found in the normal pregnant controls...

journal_title：Journal of clinical pathology

authors： Horne CH,Howie PW,Goudie RB

更新日期：1970-09-01 00:00:00

abstract：:One hundred and seventyone antenatal patients were examined for the presence of ;large colony' mycoplasmas in the vagina, and for complement-fixing antibody to Mycoplasma hominis. In 25 patients the findings before and after delivery were compared. In patients from whom M. hominis was grown, antibody was twice as comm...

journal_title：Journal of clinical pathology

authors： Jones DM

更新日期：1967-07-01 00:00:00

abstract：OBJECTIVE:We explore factors such as the blood sampling site (capillary vs venous), the equipment (HemoCue vs automated haematology analyser) and the model of the HemoCue device (201+ vs 301) that may impact haemoglobin measurements in capillary and venous blood. METHODS:Eleven studies were identified, and bias, conco...

journal_title：Journal of clinical pathology

authors： Rappaport AI,Karakochuk CD,Hess SY,Whitehead RD Jr,Namaste SML,Dary O,Parker ME,Neufeld LM,Larson LM,Newton S,Wegmuller R,Moorthy D

更新日期：2020-10-06 00:00:00

abstract：:Routine anaerobic culture of urine identified the urinary tract as the primary focus of sepsis in a postoperative patient with Bacteroides fragilis septicaemia. Specimens of urine from six other symptomatic patients grew > 10(8) cfu/litre of a Bacteroides species in pure growth. The significance of these isolates is d...

journal_title：Journal of clinical pathology

authors： Bannon J,Hatem MH,Noone M

更新日期：1998-09-01 00:00:00

abstract：:A simple laboratory method for culture of continuous ambulatory peritoneal dialysis (CAPD) fluids is described. Guidelines for antimicrobial therapy are discussed based on results from 18 patients studied over an 11-week period. Cephalosporins appeared to be a rational choice for therapy while awaiting laboratory resu...

journal_title：Journal of clinical pathology

authors： Fenton P

更新日期：1982-11-01 00:00:00

abstract：AIMS:The IHC4+C score combines assessment of oestrogen receptor (ER), progesterone receptor (PgR), HER2 and Ki67 with clinicopathological parameters to identify the risk of distant disease recurrence in patients with breast cancer, so, aiding treatment decision-making on adjuvant chemotherapy. Despite low cost and wide...

journal_title：Journal of clinical pathology

authors： Dodson A,Zabaglo L,Yeo B,Miller K,Smith I,Dowsett M

更新日期：2016-02-01 00:00:00

abstract：:Splenic pathology was analysed in 73 patients with immune thrombocytopenic purpura who underwent splenectomy for bleeding that had been resistant to adrenocorticosteroids. The mean splenic weight was 100 g. The only notable macroscopic feature was the prominence of Malpighian corpuscles in 15 cases. Microscopic examin...

journal_title：Journal of clinical pathology

authors： Hayes MM,Jacobs P,Wood L,Dent DM

更新日期：1985-09-01 00:00:00

abstract：AIM:To establish the diagnostic value of in situ hybridisation and the nested polymerase chain reaction (PCR) in detecting clinically relevant cytomegalovirus (CMV) infection in upper gastrointestinal biopsies from heart transplant patients. METHODS:Test sensitivity and specificity for detection of CMV early gene RNA ...

journal_title：Journal of clinical pathology

authors： Muir SW,Murray J,Farquharson MA,Wheatley DJ,McPhaden AR

更新日期：1998-11-01 00:00:00

abstract：AIMS:Strong thyroglobulin immunoreactivity within sinus histiocytes in a lymph node draining a papillary thyroid carcinoma was observed in a recent case. This prompted the investigation of whether thyroglobulin immunoreactivity is common in regional lymph nodes in cases of thyroid malignancy. METHODS:Eighty seven lymp...

journal_title：Journal of clinical pathology

authors： Venkatraman L,Maxwell P,McCluggage WG

更新日期：2001-04-01 00:00:00

abstract：:The congenital dyserythropoietic anaemias (CDAs) are a group of rare hereditary disorders characterised by ineffective erythropoiesis and morphological abnormalities in the erythroblasts. Patients may present with jaundice or with symptoms of anaemia, gall stones or iron overload. The diagnosis can be challenging and ...

journal_title：Journal of clinical pathology

authors： Dukka S,King MJ,Hill QA

更新日期：2014-04-01 00:00:00

abstract：AIM:To determine whether the pattern of involvement of the gastric mucosa in lymphocytic gastritis is predictive of the presence or absence of duodenal pathology. METHODS:50 cases (M:F, 26:24; median age 57 years) diagnosed as lymphocytic gastritis between 1986 and 1998 with concurrent duodenal (D2) biopsies were iden...

journal_title：Journal of clinical pathology

authors： Hayat M,Arora DS,Wyatt JI,O'Mahony S,Dixon MF

更新日期：1999-11-01 00:00:00

abstract：AIM:To establish whether infection with Epstein-Barr virus (EBV) contributed to the development of coronary artery lesions in a six year old child with an aneurysm and stenoses of the coronary arteries and suspected Kawasaki disease. METHODS:Postmortem paraffin wax sections of the coronary artery and myocardium were e...

journal_title：Journal of clinical pathology

authors： Culora GA,Moore IE

更新日期：1997-02-01 00:00:00