Detection of cytomegalovirus in upper gastrointestinal biopsies from heart transplant recipients: comparison of light microscopy, immunocytochemistry, in situ hybridisation, and nested PCR.

abstract：AIMS:In the time of COVID-19, predictive molecular pathology laboratories must still timely select oncological patients for targeted treatments. However, the need to respect social distancing measures may delay results generated by laboratory-developed tests based on sequential steps a long hands-on time. Laboratory wo...

journal_title：Journal of clinical pathology

authors： Malapelle U,De Luca C,Iaccarino A,Pepe F,Pisapia P,Russo M,Sgariglia R,Nacchio M,Vigliar E,Bellevicine C,Schmitt FC,Troncone G

更新日期：2020-05-19 00:00:00

abstract：:The serotype of 320 strains of Proteus mirabilis from clinical material was determined. Using 20 O antisera and four H antisera 61% of strains could be fully identified and 90% partially identified. A large number of serotypes were recognized but no difference was found between the serotype of organisms infecting the ...

journal_title：Journal of clinical pathology

authors： De Louvois J

更新日期：1969-05-01 00:00:00

abstract：BACKGROUND:During the last decade, whole slide images (WSI) have been used in many areas of pathology such as teaching, research, digital archiving, teleconsultation and quality assurance testing. However, WSI have not regularly been used for routine diagnosis, because of the lack of validation studies. AIM:To test th...

journal_title：Journal of clinical pathology

authors： Al-Janabi S,Huisman A,Vink A,Leguit RJ,Offerhaus GJ,Ten Kate FJ,van Dijk MR,van Diest PJ

更新日期：2012-02-01 00:00:00

abstract：:Foveolar dysplasia is an uncommon form of dysplasia that is encountered in the stomach and oesophagus in the context of Barrett’s oesophagus. Glands displaying foveolar dysplasia also show architectural abnormalities that are similar to those encountered in adenomatous dysplasia. However, from a cytological point of v...

journal_title：Journal of clinical pathology

authors： Serra S,Chetty R

更新日期：2014-10-01 00:00:00

abstract：:Autoantibodies against gastric epithelial cells are detectable in up to 50% of patients with chronic, active Helicobacter pylori gastritis. Presence of autoantibodies against canalicular structures within human parietal cells (anticanalicular autoantibodies) correlate with gastric mucosa atrophy. It has been suggested...

journal_title：Journal of clinical pathology

authors： Faller G,Steininger H,Appelmelk B,Kirchner T

更新日期：1998-03-01 00:00:00

abstract：AIM:To establish whether infection with Epstein-Barr virus (EBV) contributed to the development of coronary artery lesions in a six year old child with an aneurysm and stenoses of the coronary arteries and suspected Kawasaki disease. METHODS:Postmortem paraffin wax sections of the coronary artery and myocardium were e...

journal_title：Journal of clinical pathology

authors： Culora GA,Moore IE

更新日期：1997-02-01 00:00:00

abstract：:Haematological malignancies are a diverse group of cancers that affect the blood, bone marrow and lymphatic systems. Laboratory diagnosis of haematological malignancies is dependent on combining several technologies, including morphology, immunophenotyping, cytogenetics and molecular genetics correlated clinical detai...

journal_title：Journal of clinical pathology

authors： Snowden JA,O'Connell S,Hawkins J,Dalley C,Jack A,Mannari D,McNamara C,Scott M,Shenton G,Soilleux E,Macbeth F,Guideline Committee.

更新日期：2017-06-01 00:00:00

abstract：:The clinical, haematological, morphological and histological features of a series of 22 patients presenting with splenic lymphoma with circulating villous lymphocytes were assessed and compared with those of patients with other forms of chronic B cell leukaemia in an attempt to differentiate this condition from hairy ...

journal_title：Journal of clinical pathology

authors： Melo JV,Hegde U,Parreira A,Thompson I,Lampert IA,Catovsky D

更新日期：1987-06-01 00:00:00

abstract：:A time and temperature relationship required to destroy certain pathogenic organisms in milk feeds has been ascertained. A method of achieving this destruction by using steam at atmospheric pressure is described, and a routine method for use in milk kitchens is suggested. ...

journal_title：Journal of clinical pathology

authors： Hughes KE,Darmady EM,Drewett SE

更新日期：1966-07-01 00:00:00

abstract：:Methods of speciating Candida isolates from clinical specimens are described and the necessity of speciation is emphasized. Differences in susceptibility of C. albicans and C. tropicalis to amphotericin B were observed and the implications of this in relation to treatment with amphotericin B and the development of res...

journal_title：Journal of clinical pathology

authors： Stieritz DD,Law EJ,Holder IA

更新日期：1973-06-01 00:00:00

abstract：AIMS:This study was aimed to investigate the role of erythrocyte, platelet and reticulocyte (RET) parameters, measured by new haematological analyser Sysmex XN and C reactive protein (CRP), for early diagnosis of sepsis during intensive care unit (ICU) stay. METHODS:The study population consisted of 62 ICU patients, 2...

journal_title：Journal of clinical pathology

authors： Buoro S,Manenti B,Seghezzi M,Dominoni P,Barbui T,Ghirardi A,Carobbio A,Marchesi G,Riva I,Nasi A,Ottomano C,Lippi G

更新日期：2018-04-01 00:00:00

abstract：:This paper describes the modification of a commercially available rapid slide screening test(1) for anti-streptolysin O to give quantitative results. The modified technique is compared with the long-established haemolytic technique of Rantz and Randall (1945). The quantitative results for both techniques are shown to ...

journal_title：Journal of clinical pathology

authors： Ingram GB,Hughes JE

更新日期：1972-06-01 00:00:00

abstract：:Circulating immune complexes have been detected in the sera of 24 Nigerian children with acute poststreptococcal glomerulonephritis using two methods. There was a significant correlation between levels of soluble complexes, detected in samples taken from patients in the oliguric phase of acute nephritis, and severity ...

journal_title：Journal of clinical pathology

authors： Onyewotu II,Mee J

更新日期：1978-09-01 00:00:00

abstract：:This report describes a case of mucinous carcinoma and Müllerian metaplasia arising within an appendiceal duplication cyst found incidentally during an emergency Caesarian section. Intestinal duplication cysts are rare and although there are occasional reports of malignant transformation, this is the first case where ...

journal_title：Journal of clinical pathology

authors： Sington JD,Warren BF,Manek S

更新日期：2002-07-01 00:00:00

abstract：:It is found that serum antifibrinolytic activity is inhibitory both to the spontaneous fibrinolytic activity and to the activity of streptokinase-activated plasminogen. The titres of serum antiplasmin activity during gestation, labour, and the puerperium are all of the same order and do not differ from those in non-pr...

journal_title：Journal of clinical pathology

authors： BIEZENSKI JJ

更新日期：1960-05-01 00:00:00

abstract：AIMS:Soft tissue tumours are a heterogeneous group of neoplasms that can arise at almost every anatomical site. As they often show similar clinical and radiological findings, histology is the definitive diagnostic method and it is crucial that the surgical pathology report contains accurate, useful information for mana...

journal_title：Journal of clinical pathology

authors： Shah C,Wang J,Mubako T,Fisher C,Thway K

更新日期：2016-09-01 00:00:00

abstract：AIMS:To determine the effect of pregnancy on C4d concentrations and to assess whether C4d remains a useful disease activity marker in the management of connective tissue diseases during pregnancy. METHODS:Plasma C3, C4, and C4d concentrations were measured in 83 women at various stages of normal pregnancy and compared...

journal_title：Journal of clinical pathology

authors： Hopkinson ND,Powell RJ

更新日期：1992-01-01 00:00:00

abstract：AIMS:Dysfunctional prothrombin residue Arg596 associated mutation has been found to precipitate venous thromboembolism (VTE). In the current study we investigated the prevalence of Arg596 associated mutations in Chinese patients with VTE and explored the functional impact of Arg596Gln mutation on coagulation function i...

journal_title：Journal of clinical pathology

authors： Wu X,Li L,Ding Q,Wang X,Wu F,Wu W

更新日期：2018-07-01 00:00:00

abstract：:When the posture was changed from horizontal to vertical, or the reverse, the alteration in plasma volume and in the levels of haematocrit, haemoglobin, and plasma protein was much greater in patients with oedema or low plasma protein or albumin concentrations ("the pathological group") than in patients without these ...

journal_title：Journal of clinical pathology

authors： FAWCETT JK,WYNN V

更新日期：1960-07-01 00:00:00

abstract：AIMS:To detect cells bearing BRAF mutations in colorectal tumour samples and peritoneal washings, using a mismatch ligation assay (MLA). METHODS:DNA from 46 colorectal tumours was studied. Part of exon 15 of the BRAF gene was amplified using the polymerase chain reaction, and T-->A mutations at codon 600 were detected...

journal_title：Journal of clinical pathology

authors： Busby K,Morris A

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:Epstein's syndrome is defined as a subtype of Alport's syndrome, and is distinguished from the other subtypes by accompanying macrothrombocytopenia. Mutations in collagen IV genes are known to be involved in the pathogenesis of typical Alport's syndrome. However, the presence of an underlying genetic defect ...

journal_title：Journal of clinical pathology

authors： Naito I,Nomura S,Inoue S,Kagawa M,Kawai S,Gunshin Y,Joh K,Tsukidate C,Sado Y,Osawa G

更新日期：1997-11-01 00:00:00

abstract：INTRODUCTION:The study sought to determine whether mast cell counts in endobronchial biopsies of large airways are related to mast cell counts in the small airways. METHODS:Lungs, obtained postmortem from 10 subjects who had died of non-respiratory causes, were fixed in inflation. Mast cell densities (cells/mm(3)), de...

journal_title：Journal of clinical pathology

authors： Carroll ML,Carroll NG,Gundersen HJ,James AL

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND/AIMS:Mast cells, when activated, secrete a large number of fibrogenic factors and have been implicated in the development of fibrotic conditions of the liver, lung, and skin. There is evidence that renal fibrosis is closely linked with a chronic inflammatory cell infiltrate within the interstitium, but a pot...

journal_title：Journal of clinical pathology

authors： Roberts IS,Brenchley PE

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:The mitogenic kinin peptides formed by the serine protease, tissue kallikrein (TK1), stimulate the proliferation of tumour cells and, by increasing vascular permeability, enhance metastasis. Oesophageal mucosal epithelial cells are derived from the epithelial cell germ layer, which expresses the kallikrein-k...

journal_title：Journal of clinical pathology

authors： Dlamini Z,Bhoola KD

更新日期：2005-09-01 00:00:00

abstract：AIMS:To determine the clinical performance of three cerebrospinal fluid (CSF) IgG synthesis formulae using data obtained from two quantitation methods. METHODS:Receiver operator characteristic (ROC) analysis and decision index plots were used to compare a rate nephelometric (RN) and a rocket immunoelectrophoretic (RIE...

journal_title：Journal of clinical pathology

authors： McMillan SA,Douglas JP,Droogan AG,Hawkins SA

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:The Sysmex XN haematology instrument performs automatic reflex testing, depending on sample results. A nucleated red blood cell (NRBC) count is provided on all samples. The instrument has a smaller footprint (34%) than previous Sysmex XE analysers. METHODS:An evaluation comparing all results to the Sysmex X...

journal_title：Journal of clinical pathology

authors： Briggs C,Longair I,Kumar P,Singh D,Machin SJ

更新日期：2012-11-01 00:00:00

abstract：AIMS:Sinusoidal dilatation and congestion (SDC) in liver biopsy may be obstructive (due to venous outflow impairment) or non-obstructive in nature. The significance of this finding in the post-liver transplant setting remains unexplored. METHODS:We herein retrospectively analysed all post-transplant liver biopsies sho...

journal_title：Journal of clinical pathology

authors： Bakshi N,Rastogi A,Pamecha V,Bihari C

更新日期：2020-08-24 00:00:00

abstract：:A method is described of measuring the response of human lymphocytes to phytohaemagglutinin stimulation using iododeoxyuridine labelled with the gamma-emitting isotope (125)I. The results indicate useful clinical applications. ...

journal_title：Journal of clinical pathology

authors： Craig AW,Garrett JV,Jackson SM

更新日期：1969-09-01 00:00:00

abstract：:Splenic pathology was analysed in 73 patients with immune thrombocytopenic purpura who underwent splenectomy for bleeding that had been resistant to adrenocorticosteroids. The mean splenic weight was 100 g. The only notable macroscopic feature was the prominence of Malpighian corpuscles in 15 cases. Microscopic examin...

journal_title：Journal of clinical pathology

authors： Hayes MM,Jacobs P,Wood L,Dent DM

更新日期：1985-09-01 00:00:00

abstract：:Results of blood culture examination using the radiometric (Bactec-460) system for one year showed no overall improvement compared with those of the previous three years when a manual system with early blind subculture was used. The isolates from the manual system were available more often on solid media, 24 hours ear...

journal_title：Journal of clinical pathology

authors： Ganguli LA,Keaney MG,Hyde WA,Fraser SB

更新日期：1985-10-01 00:00:00