Abstract:
:Pathology review of gynaecological cancer specimens is often carried out as part of the working of gynaecological oncology multidisciplinary team meetings. This review describes the author's experience regarding the most common issues identified during this process. Ten subjects are covered; these range from histopathological interpretational errors to non-interpretational areas, for example, inappropriate use of the term 'microinvasive cervical carcinoma' and the use of inappropriate staging systems. This review is intended to be of practical use to the surgical pathologist reporting gynaecological cancer specimens.
journal_name
J Clin Patholjournal_title
Journal of clinical pathologyauthors
McCluggage WGdoi
10.1136/jclinpath-2011-200352subject
Has Abstractpub_date
2012-04-01 00:00:00pages
293-301issue
4eissn
0021-9746issn
1472-4146pii
jclinpath-2011-200352journal_volume
65pub_type
杂志文章abstract::Human oxalated plasma stored at 4 degrees C. until the prothrombin time is increased beyond 60 sec. is a reliable medium for assaying labile factor (factor V) because its response to added labile factor corresponds quantitatively to that of plasma from patients with congenital deficiency of this factor. Such an agreem...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.13.6.457
更新日期:1960-11-01 00:00:00
abstract::Dilated cardiomyopathy (DCM) represents a common genetic cause of mechanical and/or electrical dysfunction leading to heart failure (HF) onset for which truncating variants in titin (TTN) gene result in the most frequent mutations. Moreover, myocyte and endothelial cell apoptosis is a key endophenotype underlying card...
journal_title:Journal of clinical pathology
pub_type: 杂志文章,评审
doi:10.1136/jclinpath-2019-206404
更新日期:2020-09-01 00:00:00
abstract:AIMS:To determine whether the presence of disseminated bone marrow tumour cells at diagnosis is a prognostic factor for breast cancer patients at high risk of recurrence or bone metastasis, and to assess their presence as a criterion for evaluation of the potential benefits of adjuvant chemotherapy. METHODS:Multiple b...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.50.3.206
更新日期:1997-03-01 00:00:00
abstract::A case of chromoblastomycosis confined to the mucous membrane of one side of the nasal septum is reported. The organism was not cultivated, but its characteristics in histological preparations were typical of those of the organisms in sections of cutaneous lesions known to be caused by Phialophora pedrosoi and related...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.13.4.287
更新日期:1960-07-01 00:00:00
abstract:AIM:The prognostic significance of perineural invasion (PNI) in oesophageal adenocarcinoma (EAC) is unclear. We examined the association of PNI with clinical outcomes in patients treated with neoadjuvant chemoradiotherapy (nCRT) and surgery. METHODS:We performed a single institutional retrospective study. We evaluated...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jclinpath-2020-206424
更新日期:2020-04-21 00:00:00
abstract::A patient with chronic granulomatous disease who was being treated with steroids was diagnosed with a soft tissue Scedosporium apiospermum infection. Despite extensive treatment with antifungals progression to involve solid tissue (bone) occurred. Treatment required an HLA matched bone marrow transplant, which led to ...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.55.10.784
更新日期:2002-10-01 00:00:00
abstract:BACKGROUND:Thyrotropin-secreting adenomas (TSH-As) are rare and, according to the World Health Organization criteria (WHO 2004), a significant proportion of them present features of atypical adenomas at the time of diagnosis. AIMS:To determine the frequency of "atypical adenomas" and the significance of this definitio...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.2008.061523
更新日期:2009-05-01 00:00:00
abstract::A method utilizing a general dehydrogenase reaction has been used to demonstrate early gross myocardial infarctions. The procedure takes advantage of substrate and enzyme loss from the damaged myocardium. In the viable muscle, where endogenous substrates, coenzymes, and dehydrogenases are present, reduction of Nitro-B...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.19.5.479
更新日期:1966-09-01 00:00:00
abstract::A method is described for the quantitative separation of radioactive bile acids and neutral sterols in human faeces on a potassium hydroxide-treated silicic acid column. Results obtained with faecal extracts containing metabolites derived from radioactive cholesterol, cholic acid, and chenodeoxycholic acid show that t...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.18.1.105
更新日期:1965-01-01 00:00:00
abstract::Breast fibroepithelial lesions, including fibroadenomas and phyllodes tumours, are commonly encountered in clinical practice. As histological differences between these two related entities may be subtle, resulting in a challenging differential diagnosis, pathological techniques to assist the differential diagnosis of ...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jclinpath-2015-203231
更新日期:2015-12-01 00:00:00
abstract:AIMS:To assess the clinical efficacy of diagnostic procedures for breast cancer at a teaching hospital using internal auditing tools and quality control measures. METHODS:A retrospective assessment of 500 patients who underwent core needle biopsy (wide-bore needle biopsy; WBN) of palpable or non-palpable breast nodes ...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jclinpath-2011-200057
更新日期:2011-10-01 00:00:00
abstract::The prevalence of Helicobacter pylori infection in patients with Barrett's oesophagus was studied prospectively. A sensitive immunohistochemical staining of H pylori was performed in oesophageal and gastric biopsies of 73 patients from a surveillance group with this condition. H pylori was detected in 11 cases of Barr...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.49.2.176
更新日期:1996-02-01 00:00:00
abstract::A correlative clinical and Hemalog D study of 80 cases of chronic lymphocytic leukaemia (CLL) was performed and the results compared with those in other lymphoproliferative disorders affecting the blood (eight cases of hairy-cell leukaemia, HCL; three cases of prolymphocytic leukaemia, PLL: two cases of lymphoplasmacy...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.34.5.473
更新日期:1981-05-01 00:00:00
abstract::Several studies have recently documented the presence of persistently abnormal liver function tests in asymptomatic haemophiliacs. While the aetiology is unknown it is possible that repeated exposure to agents transmitted in blood products may be important. This study has attempted to determine the prevalence of viral...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.32.4.377
更新日期:1979-04-01 00:00:00
abstract::A case of signet-ring cell lymphoma affecting bone marrow is reported. The tumour presented as multiple lytic lesions in the lumbosacral spine. A bone biopsy specimen showed the typical appearances of signet-ring cell lymphoma, and the cells stained positively with antiserum to CD20, though neither immunoglobulin ligh...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.47.2.184
更新日期:1994-02-01 00:00:00
abstract::An alternative method for detecting the production of slime by coagulase negative staphylococci was compared with the routinely used Christensen method on 124 isolates of coagulase negative staphylococci from carriage sites, blood cultures, and infected peritoneal dialysis fluids. The alternative method requires the u...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.42.8.872
更新日期:1989-08-01 00:00:00
abstract:AIMS:To analyse the entity specific incidence and disease specific survival (DSS) of non-Hodgkin lymphomas (NHLs) in Tyrol/Austria, 1991-2000. METHODS:Data from 1307 NHLs (excluding primary cutaneous lymphomas and monoclonal gammopathies of undetermined significance) were obtained. Current status was available for all...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.2005.026815
更新日期:2006-01-01 00:00:00
abstract::Thirteen unrelated patients with idiopathic haemochromatosis (eight men, five women) were studied. The diagnosis was based on clinical, biological, and histochemical findings. HLA typing was performed in all 13 and in all of their available first degree relatives (n = 31). HLA A3 was present in nine of 13 probands (69...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.44.1.79
更新日期:1991-01-01 00:00:00
abstract::A case of combined squamous and intestinal metaplasia of the renal pelvis, associated with hydronephrosis, chronic pyelonephritis, and lithiasis, is reported. The changes are considered to be due primarily to mechanical irritation of the pelvic epithelium. ...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.22.2.187
更新日期:1969-03-01 00:00:00
abstract::The results of using a product of serum thyroxine and triiodothyronine binding coefficient, estimated by simple methods, to give a ;free thyroxine index' in normal women, in pregnant women, and in patients taking oral contraceptives is described. The method is believed to provide a reliable means of assessing thyroid ...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.21.6.767
更新日期:1968-11-01 00:00:00
abstract::This paper urges the benefits of applying more widely a method for pathology laboratory costing originally devised for a clinical chemistry department, and illustrates these with examples drawn from costing studies in three clinical laboratories. Heads of pathology departments, laboratory managers, administrators and ...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.36.9.1028
更新日期:1983-09-01 00:00:00
abstract::Distinctly increased levels of antibodies to measles virus envelope antigens haemolysin and haemagglutinin were found in the sera of patients with chronic active hepatitis compared with a normal control group, using immunofluorescence and functional tests. Similarly, a higher incidence of smooth muscle antibody of bot...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.38.11.1281
更新日期:1985-11-01 00:00:00
abstract::The necropsy findings in an elderly woman, who had been treated with methyldopa and who had died during treatment for accidental hypothermia, showed acute periductal inflammation of obviously similar duration in an entopic pancreas in the wall of the jejunum and in the ectopic pancreas. This supports the hypothesis th...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.41.4.430
更新日期:1988-04-01 00:00:00
abstract::Non-Hodgkin's lymphoma is not commonly a familial condition. This is believed to be the first two cases of primary pancreatic lymphoma within a single family. The two cases, a brother and sister, both presented in their 60s and were diagnosed histologically as having high grade B cell lymphoma affecting the pancreas, ...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.51.1.80
更新日期:1998-01-01 00:00:00
abstract:AIM:To ascertain the views of Scottish hospital laboratory users on aspects of regional and supraregional biochemical services offered by the Institute of Biochemistry at Glasgow Royal Infirmary. METHODS:A questionnaire was circulated asking questions or inviting opinions under various headings, including current patt...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.47.5.395
更新日期:1994-05-01 00:00:00
abstract:BACKGROUND/AIMS:CD10 (CALLA) has recently been reported to be expressed in spindle cell neoplasia, and has been used to differentiate endometrial stromal sarcoma from leiomyoma and leiomyosarcoma. In the breast, myoepithelial cells express CD10, but there are few studies of the expression of CD10 in mammary fibroepithe...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.2004.020917
更新日期:2005-02-01 00:00:00
abstract:AIMS:The authors previously demonstrated that nasal mucus cyclic adenosine 3', 5'-monophosphate (cAMP) and cyclic 3', 5'-guanosine monophosphate (cGMP) were lower in patients with smell and taste dysfunction than in normal individuals. To learn more about these differences this study related levels of nasal mucus cAMP ...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jclinpath-2012-200698
更新日期:2012-05-01 00:00:00
abstract::An influenza virus vaccine containing the purified surface haemagglutinin and neuraminidase antigens of A/Victoria/75 and B/Hong Kong/73 viruses adsorbed to an aluminium hydroxide gel was assessed for reactogenicity and immunogenicity in children aged 4 to 11 years, since there is no influenza virus vaccine available ...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.32.6.534
更新日期:1979-06-01 00:00:00
abstract:AIMS:To evaluate the effect of microwave irradiation on the staining quality of a range of commonly used primary antibodies in archival, formalin fixed, paraffin wax embedded material, with emphasis on antibodies that have previously worked successfully only on frozen tissue. METHODS:Immunocytochemistry (streptavidin-...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.47.5.448
更新日期:1994-05-01 00:00:00
abstract::Serum IgM, IgA, and IgG concentrations were measured in 19 patients suffering from blood-dependent homozygous beta-thalassaemia. The study was prospective and the same patients served as presplenectomy controls. IgG levels rose rapidly and continuously after splenectomy IgA levels also rose but not so sharply. IgM fel...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.31.6.546
更新日期:1978-06-01 00:00:00