Coagulase-negative staphylococci causing endocarditis after cardiac surgery.

abstract：:Assessment of ERBB2 (HER2) status in breast carcinomas has become critical in determining response to the humanised monoclonal antibody trastuzumab. The current joint College of American Pathologists and the American Society of Clinical Oncology guidelines for the evaluation of HER2 status in breast carcinoma involve ...

journal_title：Journal of clinical pathology

authors： Gruver AM,Peerwani Z,Tubbs RR

更新日期：2010-03-01 00:00:00

abstract：AIMS:To study the homozygous deletion and methylation status of the 5' CpG island of the p16 and p15 genes (9p21) in a set of primary advanced head and neck squamous cell carcinomas (SCC) and to test whether inactivation of these genes by these mechanisms contributes to head and neck SCC development. METHODS:DNA was e...

journal_title：Journal of clinical pathology

authors： González MV,Pello MF,López-Larrea C,Suárez C,Menéndez MJ,Coto E

更新日期：1997-06-01 00:00:00

abstract：AIM:To develop a unified diagnostic approach for the detection of human papillomavirus (HPV) DNA in skin and mucosal biopsies from both immunocompetent and immunosuppressed individuals using a degenerate polymerase chain reaction (PCR) method. METHODS:The sensitivity and specificity of three published degenerate prime...

journal_title：Journal of clinical pathology

authors： Surentheran T,Harwood CA,Spink PJ,Sinclair AL,Leigh IM,Proby CM,McGregor JM,Breuer J

更新日期：1998-08-01 00:00:00

abstract：:The excretion of 2,3-dinor-6-keto prostaglandin F1 alpha, a major urinary metabolite of prostacyclin, and the formation of thromboxane B2, a stable metabolite of thromboxane A2, by platelets stimulated by adenosine diphosphate, were studied in alcoholics, who had been admitted for detoxification. Once prolonged heavy ...

journal_title：Journal of clinical pathology

authors： Neiman J,Hillbom M,Benthin G,Anggård EE

更新日期：1987-05-01 00:00:00

abstract：:Cytological diagnosis in a series of 153 skin lesions is presented. The diagnosis in each case has been compared with the clinical assessment and, where available, the biopsy result (85 lesions). Of 131 basal cell carcinomas, a cytological diagnosis was possible in 124 while biopsyl failed to identify two of the 73 le...

journal_title：Journal of clinical pathology

authors： Brown CL,Klaber MR,Robertson MG

更新日期：1979-04-01 00:00:00

abstract：:The mean areas of lymphoid follicles have been determined in 20 specimens of malignant follicular (centrocytic-centroblastic) lymphoma, 15 specimens of reactive follicular hyperplasia and 10 palatine tonsils. In all of the benign specimens and whenever possible for those showing malignancy, the areas of both the whole...

journal_title：Journal of clinical pathology

authors： Crocker J,Jones EL,Curran RC

更新日期：1983-09-01 00:00:00

abstract：AIM:To investigate the association between the quantity of gastric chemokine mRNA expression, severity of gastritis, and cagA positivity in Helicobacter pylori associated gastritis. METHODS:In 83 dyspeptic patients, antral and corpus biopsies were taken for semiquantitative reverse transcription polymerase chain react...

journal_title：Journal of clinical pathology

authors： Shimoyama T,Everett SM,Dixon MF,Axon AT,Crabtree JE

更新日期：1998-10-01 00:00:00

abstract：:Phyllodes tumours (PTs) of the breast are true biphasic neoplasms within which interactions between the epithelium and stroma are critical for tumour development and progression. Despite numerous studies reporting the results of ancillary marker investigations in PTs, the current histological grading systems remain un...

journal_title：Journal of clinical pathology

authors： Karim RZ,O'Toole SA,Scolyer RA,Cooper CL,Chan B,Selinger C,Yu B,Carmalt H,Mak C,Tse GM,Tan PH,Putti TC,Lee CS

更新日期：2013-06-01 00:00:00

abstract：:Apocrine morphology is a common phenomenon encountered in everyday breast pathology practice, and is defined as cuboidal or columnar cells exhibiting abundant eosinophilic granular cytoplasm, prominent apical granules, a low nuclear-cytoplasmic ratio, and round nuclei with pale chromatin and prominent nucleoli. Apocri...

journal_title：Journal of clinical pathology

authors： D'Arcy C,Quinn C

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Intraoperative frozen section (FS) examination in thoracic surgery is a reliable method for diagnosis and staging of pulmonary lesions and provides a valuable guide in directing the extent of the ongoing surgical procedure. However, the contribution of touch preparation cytology (TPC) to FS diagnosis remains...

journal_title：Journal of clinical pathology

authors： Rakha EA,Haider A,Patil S,Fourtan H,Chaudry Z,Soomro IN

更新日期：2010-08-01 00:00:00

abstract：:Here, we report the pathological findings of nine complete autopsies of individuals who died in community settings in the UK, three of which were positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), three tested negative for SARS-CoV-2 but are likely false negatives, and three died of other respi...

journal_title：Journal of clinical pathology

authors： Youd E,Moore L

更新日期：2020-12-01 00:00:00

abstract：:This report describes a patient with a gastric biopsy specimen showing histomorphological and immunohistochemical appearances indistinguishable from those usually present in lymphocytic gastritis, a rare condition of unknown aetiology with a distinctive phenotype. The patient had a history of a biopsy confirmed T cell...

journal_title：Journal of clinical pathology

authors： Nga ME,Tan SH,Teh M,Koay ES,Chong SM,Putti TC,Salto-Tellez M

更新日期：2004-11-01 00:00:00

abstract：AIMS:To assess the incidence of nocardia infection over 15 years in a tertiary care hospital. METHODS:Over a 15 year period, Nocardia spp were isolated from 20 patients hospitalised at the Geneva University Hospitals, Switzerland. RESULTS:Sixteen patients had one or more underlying conditions. The median time between...

journal_title：Journal of clinical pathology

authors： Matulionyte R,Rohner P,Uçkay I,Lew D,Garbino J

更新日期：2004-08-01 00:00:00

abstract：:Antibiotic discs from Oxoid, Mast, AB Biodisk, Difco, and Baltimore Biological Laboratories were compared, where discs of similar antibiotic content were available, in diffusion-sensitivity tests against organisms of known sensitivity. Discs from Oxoid and Mast gave zones 1-5 mm larger than discs from other manufactur...

journal_title：Journal of clinical pathology

authors： Brown DF,Kothari D

更新日期：1975-10-01 00:00:00

abstract：BACKGROUND:Ewing's sarcoma and peripheral primitive neuroectodermal tumour (pPNET) are now regarded as two morphological ends of a spectrum of neoplasms, characterised by a t(11;22) or other related chromosomal translocation involving the EWS gene on chromosome 22 and referred to as Ewing family of tumours (EFTs). EFTs...

journal_title：Journal of clinical pathology

authors： McCluggage WG,Sumathi VP,Nucci MR,Hirsch M,Dal Cin P,Wells M,Flanagan AM,Fisher C

更新日期：2007-06-01 00:00:00

abstract：AIM:To determine the prognostic significance and clinical relevance of cathepsin D detected by immunocytochemical assays (ICAs) in breast carcinomas. METHODS:151 patients presenting with palpable or impalpable breast carcinomas and who had not received any kind of adjuvant chemotherapy or endocrine therapy who were op...

journal_title：Journal of clinical pathology

authors： Charpin C,Garcia S,Bouvier C,Martini F,Lavaut M,Allasia C,Bonnier P,Andrac L

更新日期：1997-07-01 00:00:00

abstract：:This review surveys the staging systems used for the classification of colorectal carcinomas, including the TNM system, and focuses on the assessment of the nodal stage of the disease. It reviews the quantitative requirements for a regional metastatic work up, and some qualitative features of lymph nodes that may help...

journal_title：Journal of clinical pathology

authors： Cserni G

更新日期：2003-05-01 00:00:00

abstract：AIMS:To assess the association between Helicobacter pylori-associated gastritis and HLA-DR antigen (class II antigen) expression. METHODS:Fifty endoscopic gastric biopsy specimens were studied for the presence of H pylori, degree and type of inflammation, and for HLA-DR antigen expression in the epithelium. The cases ...

journal_title：Journal of clinical pathology

authors： Wee A,Teh M,Kang JY

更新日期：1992-01-01 00:00:00

abstract：:Two cases of Wegener's granulomatosis are described in which the early and predominating lesions were found in the breast. The histological features of breast necrosis with granulomatous inflammation and widespread vasculitis in the breast in the absence of any demonstrable pathogens enabled a presumptive diagnosis to...

journal_title：Journal of clinical pathology

authors： Pambakian H,Tighe JR

更新日期：1971-05-01 00:00:00

abstract：AIM:To investigate whether there is loss of the p27Kip1 protein in developing cervical cancer and whether p27Kip1 immunoreactivity has any relation to the proliferative indicator Ki-67. METHODS:The expression of p27Kip1 and Ki-67 was assessed by immunohistochemistry in serial sections from normal epithelium (13), low ...

journal_title：Journal of clinical pathology

authors： Troncone G,Vetrani A,de Rosa G,Gerbasio D,Palombini L

更新日期：1999-12-01 00:00:00

abstract：:Haemoglobin (Hb) Bonn is a newly described benign Hb variant that causes falsely depressed oxygen saturation as measured by pulse oximetry. It was found to be associated with mild haemolysis. Since its first report in a German family, no further cases have been documented in the literature. We report the first Chinese...

journal_title：Journal of clinical pathology

authors： So CC,Chan AY,Chow EY,Lin SY,Yip SF,Szeto SC,Chan LC

更新日期：2010-10-01 00:00:00

abstract：:Two unusual ovarian tumours thought to be of Wolffian identity, one of them malignant, are described. They showed packed combinations of adenopapillary, tubular, trabecular and diffuse patterns, a sharp and generalised periodic acid-Schiff (PAS)-positive basement membrane and areas of elastic network. A review of publ...

journal_title：Journal of clinical pathology

authors： Hughesdon PE

更新日期：1982-05-01 00:00:00

abstract：AIMS:Computational pathology platforms incorporate digital microscopy with sophisticated image analysis to permit rapid, continuous measurement of protein expression. We compared two computational pathology platforms on their measurement of breast tumour oestrogen receptor (ER) and progesterone receptor (PR) expression...

journal_title：Journal of clinical pathology

authors： Ahern TP,Beck AH,Rosner BA,Glass B,Frieling G,Collins LC,Tamimi RM

更新日期：2017-05-01 00:00:00

abstract：:The analytical goals inferred desirable by a group of clinicians for the imprecisions of a wide range of analytes have been studied by survey. The goals required have not in general become more stringent in the past decade and are not as demanding as those promulgated by laboratory professionals. Clinical biochemistry...

journal_title：Journal of clinical pathology

authors： Barrett AE,Cameron SJ,Fraser CG,Penberthy LA,Shand KL

更新日期：1979-09-01 00:00:00

abstract：AIMS:To test whether a hypoacidic environment may potentially "stress" Helicobacter pylori DNA, encouraging the emergence of strain variation. METHODS:This hypothesis was tested by inducing prolonged hypoacidity with omeprazole, a potent antisecretory drug. The genomic DNA of H pylori was studied by electrophoretic se...

journal_title：Journal of clinical pathology

authors： Fraser AG,Bickley J,Owen RJ,Pounder RE

更新日期：1992-12-01 00:00:00

abstract：:As part of a quality assurance programme at the Aga Khan University Medical Centre, Karachi, Pakistan, all hysterectomy specimens were reviewed from January 1986 to December 1989. Adenomyosis was found in 237 of the 419 (56.5%) specimens studied. Of these 237 patients, 232 (97.9%) were parous and 196 (82.8%) were in t...

journal_title：Journal of clinical pathology

authors： Shaikh H,Khan KS

更新日期：1990-10-01 00:00:00

abstract：:Activation of the complement system, the main humoral mediator of inflammation, is restrained by the action of enzyme inhibitors including alpha 1-antitrypsin. Deficiency leads to chronic liver disease in about one in five children with this genetic defect. Complement activation was investigated in 34 children with al...

journal_title：Journal of clinical pathology

authors： Littleton ET,Bevis L,Hansen LJ,Peakman M,Mowat AP,Mieli-Vergani G,Vergani D

更新日期：1991-10-01 00:00:00

abstract：BACKGROUND/AIMS:To evaluate the need for routine histopathological analysis of enucleated/eviscerated eyes and changes in indications for eye removal. METHODS:Retrospective review of all enucleation/evisceration histopathology reports over 20 years. Clinical history was correlated with pathological findings. Two 10 ye...

journal_title：Journal of clinical pathology

authors： Saeed MU,Chang BY,Khandwala M,Shivane AG,Chakrabarty A

更新日期：2006-02-01 00:00:00

abstract：:A study of 260 patients with non-Hodgkin's lymphoma (NHL) who underwent bilateral bone marrow biopsy at initial diagnosis showed marrow disease in 99 (38%) cases. The highest incidence of disease (83%) was seen in small lymphocytic lymphoma (SLL) and the lowest (19%) in diffuse large cell lymphoma (DLCL). Among cases ...

journal_title：Journal of clinical pathology

authors： Juneja SK,Wolf MM,Cooper IA

更新日期：1990-08-01 00:00:00

abstract：:Langerhans' cells were studied in the epidermis of two patients with active Behçet's disease and compared with those in two normal controls. Ultrastructural morphology and the percentage of Langerhans' cells found were similar in patients' (1.88%) and the control epidermis (1.79%). The density of Langerhans' cells in ...

journal_title：Journal of clinical pathology

authors： Kohn S,Haim S,Gilhar A,Friedman-Birnbaum R,Nir I

更新日期：1984-06-01 00:00:00