Comparison of the effects of filtration leucapheresis and discontinuous flow centrifugation leucapheresis on granulocyte microbicidal function.

abstract：:The term "dysplastic" melanocytic naevus has recently been used to describe pigmented naevi with unusual histological and clinical features. There is currently no clear clinical or pathological definition of the term, and this has led to a lack of comparability of material described in reports on these lesions. As a r...

journal_title：Journal of clinical pathology

authors： Seywright MM,Doherty VR,MacKie RM

更新日期：1986-02-01 00:00:00

abstract：:During the last decade, a dramatic rise in the development and application of artificial intelligence (AI) tools for use in pathology services has occurred. This trend is often expected to continue and reshape the field of pathology in the coming years. The deployment of computational pathology and applications of AI ...

journal_title：Journal of clinical pathology

authors： Rakha EA,Toss M,Shiino S,Gamble P,Jaroensri R,Mermel CH,Chen PC

更新日期：2020-08-06 00:00:00

abstract：BACKGROUND:Breast-conserving surgery currently focuses on improving margin clearance and excision volume, the main pathology report parameters for oncological and cosmetic outcomes. AIM:To quantitatively evaluate discrepancies in surgical and pathological estimates of breast specimen sizes, including the influence of ...

journal_title：Journal of clinical pathology

authors： Krekel NM,van Slooten HJ,Barbé E,de Lange de Klerk ES,Meijer S,van den Tol MP

更新日期：2012-03-01 00:00:00

abstract：AIMS:This is a qualitative study of the perceived learning needs of trainees for graded responsibility in histopathological training in the UK. METHODS:A focus group with trainees and interviews with consultants was carried out. Participants were asked 'What do you perceive are the learning needs of histopathology tra...

journal_title：Journal of clinical pathology

authors： Finall A,Allery L

更新日期：2016-01-01 00:00:00

abstract：:Nearly two thousand clinical samples were examined by direct gas-liquid chromatography over a three year period. Absence of volatile fatty acids (VFAs) in the samples correlated well with negative culture results for anaerobic bacteria. In general the presence of acetic acid alone correlated well with the presence of ...

journal_title：Journal of clinical pathology

authors： Watt B,Geddes PA,Greenan OA,Napier SK,Mitchell A

更新日期：1982-07-01 00:00:00

abstract：:The principles which should govern the planning of benching and services for new laboratories are enumerated. These include the necessity for long-term planning, flexibility, and economy. The ;Cardiff benching system' where the benches are composed of units that consist of an independent movable table base, a removabl...

journal_title：Journal of clinical pathology

authors： LAURENCE KM

更新日期：1963-09-01 00:00:00

abstract：:An enzyme linked immunosorbent assay (ELISA) to measure free serum IgG antibodies to Pseudomonas aeruginosa in patients with cystic fibrosis was developed. Seven strains of P aeruginosa cells, treated with glutaraldehyde and representing the most commonly isolated serotypes in our cystic fibrosis unit, were used. The ...

journal_title：Journal of clinical pathology

authors： Brett MM,Ghoneim AT,Littlewood JM,Losowsky MS

更新日期：1986-10-01 00:00:00

abstract：:Group-specific polysaccharides of Neisseria meningitidis groups A and C have been demonstrated by means of a rapid, sensitive slide agglutination test with latex particles coated with antibodies. In this manner, the diagnosis can be made from the cerebrospinal fluid of patients with meningococcal meningitis caused by ...

journal_title：Journal of clinical pathology

authors： Severin WP

更新日期：1972-12-01 00:00:00

abstract：:In-vivo studies of fibrinogen metabolism were carried out using an I-120 labelled preparation of fibrinogen supplied commercially by the Radiochemical Centre, Amerhsham for use in the diagnosis of deep venous thrombosis. These studies show that the material is suitable for obtaining the main metabolic parameters of c...

journal_title：Journal of clinical pathology

authors： Bradley J,Hickman JA

更新日期：1975-06-01 00:00:00

abstract：:Early epidemiological studies of cervical neoplasia suggested a causal relation with sexual activity and human papillomaviruses (HPVs) have emerged as prime suspects as venerally transmitted carcinogens. HPVs fall into two broad camps: low risk types, associated with cervical condylomas and CIN 1; and high risk types ...

journal_title：Journal of clinical pathology

authors： Arends MJ,Buckley CH,Wells M

更新日期：1998-02-01 00:00:00

abstract：:Factor VII levels have been measured in 100 patients with liver disease following parenteral vitamin K1 therapy. There was good agreement between specific factor VII measurements and the one-stage prothrombin time apart from six patients with compensated cirrhosis in whom the prothrombin time was prolonged despite the...

journal_title：Journal of clinical pathology

authors： Green G,Poller L,Thomson JM,Dymock IW

更新日期：1976-11-01 00:00:00

abstract：:Levels of the serum complement components, C3 and C4, in patients with Crohn's disease, ulcerative colitis, and miscellaneous gastrointestinal disorders were compared with those of normal blood donors. Significant increases of both components were found in all three patient groups, the highest being in patients with C...

journal_title：Journal of clinical pathology

authors： Ross IN,Thompson RA,Montgomery RD,Asquith P

更新日期：1979-08-01 00:00:00

abstract：BACKGROUND:Although in vitro breast cancer models have demonstrated a role for protein kinase C (PKC) alpha and delta isoforms in endocrine insensitivity and resistance respectively, there is currently little clinical evidence to support these observations. AIMS:To define the pattern of PKC alpha and delta expression ...

journal_title：Journal of clinical pathology

authors： Assender JW,Gee JM,Lewis I,Ellis IO,Robertson JF,Nicholson RI

更新日期：2007-11-01 00:00:00

abstract：INTRODUCTION:Bone marrow aspiration and biopsy is an invasive procedure associated with morbidity and mortality risk. We compared a powered bone marrow aspiration and biopsy device to the traditional method by relatively assessing pain scores, procedure times, biopsy capture rates, quality of material retrieved, and sa...

journal_title：Journal of clinical pathology

authors： Swords RT,Anguita J,Higgins RA,Yunes AC,Naski M,Padmanabhan S,Kelly KR,Mahalingam D,Philbeck T,Miller L,Puga TA,Giles FJ,Kinney MC,Brenner AJ

更新日期：2011-09-01 00:00:00

abstract：:The cardiovascular system is a common target of amyloidosis. This review presents the current clinical and diagnostic approach to amyloidosis, with the emphasis on cardiovascular involvement. It summarises recent nomenclature, classification, and pathogenesis of amyloidosis. In addition, non-invasive possibilities are...

journal_title：Journal of clinical pathology

authors： Kholová I,Niessen HW

更新日期：2005-02-01 00:00:00

abstract：:Three selective chromogenic culture media (CHROMagars ESBL, CTX-M and KPC) were evaluated for their ability to support the growth of nine Klebsiella pneumoniae isolates producing OXA-48 carbapenemase in combination with other β-lactamases. CHROMagar ESBL and CHROMagar KPC were the most sensitive media, supporting grow...

journal_title：Journal of clinical pathology

authors： Hornsey M,Phee L,Woodford N,Turton J,Meunier D,Thomas C,Wareham DW

更新日期：2013-04-01 00:00:00

abstract：AIMS:To investigate the expression of the placental cell-specific associated proteins in infantile haemangioma (IH). METHODS:Immunohistochemical staining was used to investigate the expression of human chorionic gonadotrophin (hCG), human placental lactogen (hPL), human leucocyte antigen-G (HLA-G), cytokeratin 7 (CK7)...

journal_title：Journal of clinical pathology

authors： Itinteang T,Tan ST,Guthrie S,Tan CE,McIntyre BC,Brasch HD,Day DJ

更新日期：2011-10-01 00:00:00

abstract：AIMS:To investigate the histopathological features of the synovial lining of the knee following implantation of an artificial cruciate ligament. METHODS:Eighty two patients underwent anterior cruciate ligament reconstruction for chronic, symptomatic instability of the knee. The cruciate ligament was reconstructed with...

journal_title：Journal of clinical pathology

authors： Barry M,Thomas SM,Rees A,Shafighian B,Mowbray MA

更新日期：1995-06-01 00:00:00

abstract：:Sera from 20 cases of toxoplasmic lymphadenopathy were examined by an enzyme linked immunosorbent assay toxoplasma IgG avidity (ELISA) at two laboratories. The results obtained were largely in agreement and showed that sera from patients with acute infection had low avidity IgG (30% or less), whereas sera from patient...

journal_title：Journal of clinical pathology

authors： Joynson DH,Payne RA,Rawal BK

更新日期：1990-12-01 00:00:00

abstract：:Pre-eclampsia complicated by deep jaundice occurred in a previously healthy primigravida. The main aetiological factor was disseminated intravascular coagulation; this caused both haemolysis and liver cell necrosis. Liver biopsy showed fibrin thrombi in the capillaries with microhaemorrhages and loss of periportal liv...

journal_title：Journal of clinical pathology

authors： Long RG,Scheuer PJ,Sherlock S

更新日期：1977-03-01 00:00:00

abstract：PURPOSE:To investigate p53 and hepatoma-derived growth factor (HDGF) expression and their association with clinicopathological features of Ewing family tumour (EFT). EXPERIMENTAL DESIGN:A total of 108 cases of EFT were retrospectively analysed. p53 and HDGF expression were detected using immunohistochemistry, and the ...

journal_title：Journal of clinical pathology

authors： Yang Y,Zhen T,Zhang F,Dai S,Kang L,Liang Y,Xue L,Han A

更新日期：2014-03-01 00:00:00

abstract：AIMS:To investigate the correlation between centrally assessed human epidermal growth factor receptor 2 (HER2) immunohistochemistry (IHC) and fluorescence in situ hybridisation (FISH) results and response to treatment of patients with metastatic breast cancer enrolled in a first-line, phase II, open-label, 3-weekly tra...

journal_title：Journal of clinical pathology

authors： Hofmann M,Stoss O,Gaiser T,Kneitz H,Heinmöller P,Gutjahr T,Kaufmann M,Henkel T,Rüschoff J

更新日期：2008-01-01 00:00:00

abstract：AIM:An audit of serrated polyps diagnosed over a 4-year period: 2009 to 2012 was undertaken to ascertain the reporting trends of sessile serrated polyps (SSP). METHODS:All right sided hyperplastic polyps (HP) proximal to the splenic flexure and all polyps designated SSP were retrieved from the study period. Three path...

journal_title：Journal of clinical pathology

authors： Gill P,Wang LM,Bailey A,East JE,Leedham S,Chetty R

更新日期：2013-08-01 00:00:00

abstract：:A patient with chronic granulomatous disease who was being treated with steroids was diagnosed with a soft tissue Scedosporium apiospermum infection. Despite extensive treatment with antifungals progression to involve solid tissue (bone) occurred. Treatment required an HLA matched bone marrow transplant, which led to ...

journal_title：Journal of clinical pathology

authors： Gompels MM,Bethune CA,Jackson G,Spickett GP

更新日期：2002-10-01 00:00:00

abstract：:In 12 normal subjects plasma calcium and phosphorus concentrations were estimated during a normal working day. In the individual subjects fluctuations from the fasting values occurred during the period of study, but at no time during that period did the mean values differ significantly from the fasting plasma calcium ...

journal_title：Journal of clinical pathology

authors： Wills MR

更新日期：1970-12-01 00:00:00

abstract：AIMS:To describe and evaluate two apparently unique cases of inverted hyperplastic (metaplastic) polyposis of the colon. METHODS:The cases were analysed by standard histopathological, histochemical, and immunohistochemical techniques and the findings compared with those of regular hyperplastic polyps of the colorectum...

journal_title：Journal of clinical pathology

authors： Shepherd NA

更新日期：1993-01-01 00:00:00

abstract：:A case of a 20 year old Japanese woman who developed thyroid cancer exhibiting unusual cribriform structures while being followed up for familial adenomatous polyposis/Gardner's syndrome is reported. The patient presented with osteomas, pigmented retinal lesions, and adenomas of the duodenum and the papilla of Vater, ...

journal_title：Journal of clinical pathology

authors： Hizawa K,Iida M,Yao T,Aoyagi K,Oohata Y,Mibu R,Yamasaki K,Hirata T,Fujishima M

更新日期：1996-07-01 00:00:00

abstract：:A case of IgD myeloma accompanied by diffuse osteosclerosis is reported. A trephine biopsy specimen showed only reticulin fibrosis, but histomorphometric analysis of a full thickness transiliac bone biopsy specimen showed increased trabecular bone mass, with no local deposit of tumour. An excess of bone surfaces were ...

journal_title：Journal of clinical pathology

authors： MacCallum PK,Freemont AJ,Geary CG,Liu Yin JA

更新日期：1988-05-01 00:00:00

abstract：AIMS:To estimate the expression of substance P in the haematopoietic cells of hypoplastic bone marrow and define its relationship with the course of bone marrow hypoplasia. METHODS:Bone marrow specimens were obtained from 42 children with bone marrow hypoplasia who were hospitalised in the Department of Pediatric Onco...

journal_title：Journal of clinical pathology

authors： Nowicki M,Ostalska-Nowicka D,Konwerska A,Miskowiak B

更新日期：2006-09-01 00:00:00

abstract：AIMS:To assess the possible role of hypoxia in the formation of axonal bulbs. METHODS:Study material comprised sections from 28 brains showing evidence of cerebral hypoxia with no history of head injury, four with a history of head trauma but no evidence of hypoxic change, eight with a history of head trauma and hypox...

journal_title：Journal of clinical pathology

authors： Kaur B,Rutty GN,Timperley WR

更新日期：1999-03-01 00:00:00