Relationship between hepatic morphology and clinical and biochemical findings in morbidly obese patients.

Abstract:

:This study was undertaken to determine the interrelations between clinico-biochemical parameters and hepatic morphology in markedly obese patients. One hundred and sixty-six women and 52 men comprise this series. There was a statistically significant association of carbohydrate metabolism disturbance with increasing age and corpulence and, in women, with hyperuricaemia and morphological alterations of the liver. Menstrual irregularities also correlated well with hepatic morphology. The livers frequently exhibited steatosis, but other morphological changes were mild. Compared with women, men had higher triglyceride values, more severe hepatic involvement, and poorer correlation of carbohydrate disturbances with hepatic histology. The results indicate a central role of the impaired carbohydrate utilization in the biochemical and hepatic alterations of obesity.

journal_name

J Clin Pathol

authors

Manes JL,Taylor HB,Starkloff GB

doi

10.1136/jcp.26.10.776

subject

Has Abstract

pub_date

1973-10-01 00:00:00

pages

776-83

issue

10

eissn

0021-9746

issn

1472-4146

journal_volume

26

pub_type

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