Cytochemical profile of B and T leukaemic lymphocytes with special reference to acute lymphoblastic leukaemia.

abstract：AIMS/BACKGROUND:Telomerase is an enzyme that is expressed in most human neoplasms and is associated with tumour immortality. Determination of the point in neoplastic transformation at which telomerase is expressed may aid the understanding of tumour pathogenesis and progression. Despite numerous reports on telomerase, ...

journal_title：Journal of clinical pathology

authors： Kleinschmidt-DeMasters BK,Hashizumi TL,Sze CI,Lillehei KO,Shroyer AL,Shroyer KR

更新日期：1998-04-01 00:00:00

abstract：:In a retrospective series of 40 appendiceal tumours occurring over a 10-year period, 30 were carcinoid tumours of classical histological pattern, five were adenocarcinomas, and two were tumours intermediate in pattern between carcinoid and carcinoma. The remaining three tumours were secondaries from primary colonic tu...

journal_title：Journal of clinical pathology

authors： Jones RA,MacFarlane A

更新日期：1976-08-01 00:00:00

abstract：AIMS:To evaluate two detailed step sectioning protocols for sentinel lymph nodes (SLNs). METHODS:After vital dye or combined dye and radiocolloid guided biopsy, SLNs were fixed in formalin and embedded in paraffin wax. In protocol A, SLNs from 123 patients were sectioned in steps of 50-100 micro m, whereas in protocol...

journal_title：Journal of clinical pathology

authors： Cserni G

更新日期：2002-12-01 00:00:00

abstract：AIMS:Evidence suggests that the presence of tumour necrosis is an adverse prognostic factor in renal cell carcinoma (RCC). However, it has also been shown that tumour regression, a microscopic feature associated with necrosis, may be a favourable short term prognostic factor in RCC. METHODS:Pathology reports of 253 RC...

journal_title：Journal of clinical pathology

authors： Foria V,Surendra T,Poller DN

更新日期：2005-01-01 00:00:00

abstract：:A severe non-dose related skin eruption attributable to treatment with captopril was recently reported: this is distinct from the dose related rashes that have been widely described. Ultrastructural and immunohistochemical studies were carried out to determine in detail the histological features of this eruption: the ...

journal_title：Journal of clinical pathology

authors： Furness PN,Goodfield MJ,MacLennan KA,Stevens A,Millard LG

更新日期：1986-08-01 00:00:00

abstract：:In patients with chronic renal failure, blood samples for laboratory analysis are often taken via dialysis catheters. This report describes a case of gross spurious hypernatraemia in a blood sample collected from a patient undergoing haemodialysis. After centrifugation of the blood sample in question, the separator ge...

journal_title：Journal of clinical pathology

authors： Srivastava R,Murphy MJ,Card J,Severn A,Fraser CG

更新日期：2004-12-01 00:00:00

abstract：:Serum glycocholic acid (SGC) was measured by radioimmunoassay in 277 samples from 122 children with hepatobiliary disorders and from 23 healthy age-matched controls. In patients with hepatobiliary disease the SGC was more frequently abnormal (83%) than values for serum albumin (7%), prothrombin time (17%), bilirubin (...

journal_title：Journal of clinical pathology

authors： Matsui A,Psacharopoulos HT,Mowat AP,Portmann B,Murphy GM

更新日期：1982-09-01 00:00:00

abstract：AIMS:To compare the sensitivity and specificity of new rabbit monoclonal antibody SP3 with those of mouse monoclonal and rabbit polyclonal antibodies using HER2 amplification defined by chromogenic in situ hybridisation (CISH) as the gold standard. METHODS:Serial sections from tissue microarrays (TMAs) containing 84 b...

journal_title：Journal of clinical pathology

authors： Nunes CB,Rocha RM,Reis-Filho JS,Lambros MB,Rocha GF,Sanches FS,Oliveira FN,Gobbi H

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Over 90% of Ewing's sarcoma/primitive neuroectodermal tumour (ES/PNET) cases have the t(11;22) chromosomal rearrangement, which is also found in other small round cell tumours, including desmoplastic small round cell tumour (DSRCT) and clear cell sarcoma (CCS). Although this rearrangement can be analysed by ...

journal_title：Journal of clinical pathology

authors： Yamaguchi U,Hasegawa T,Morimoto Y,Tateishi U,Endo M,Nakatani F,Kawai A,Chuman H,Beppu Y,Endo M,Kurotaki H,Furuta K

更新日期：2005-10-01 00:00:00

abstract：:DNA typing was requested to investigate a presumptive cancer diagnosis error by confirming whether benign and cancerous prostatic tissue in the same presurgical haematoxylin and eosin stained slide belonged to the same person. After independent histological re-examination of the slide by a pathologist, manual slide di...

journal_title：Journal of clinical pathology

authors： Alonso A,Alves C,Suárez-Mier MP,Albarrán C,Pereira L,Fernández de Simón L,Martín P,García O,Gusmão L,Sancho M,Amorim A

更新日期：2005-01-01 00:00:00

abstract：:Endocardial fibroelastosis, defined as an endocardium in excess of 30 microns thick, was found in 10 out of 34 cases of hydrops fetalis in a review of 1589 perinatal necropsies carried out between 1976 and 1989. The infants comprised 16 cases of rhesus haemolytic disease, of whom three had endocardial fibroelastosis, ...

journal_title：Journal of clinical pathology

authors： Newbould MJ,Armstrong GR,Barson AJ

更新日期：1991-07-01 00:00:00

abstract：:Histological assessment of melanocytic naevi constitutes a substantial proportion of a dermatopathologist's daily workload. Although they may be excised for cosmetic reasons, most lesions encountered are clinically atypical and are biopsied or excised to exclude melanoma. Although dysplastic naevi are most often encou...

journal_title：Journal of clinical pathology

authors： Culpepper KS,Granter SR,McKee PH

更新日期：2004-11-01 00:00:00

abstract：:Platelet adhesiveness has been assessed on whole blood from a series of 34 diabetics and 50 control subjects using adenosine diphosphate (A.D.P.) and by adherence to glass microspherules (ballotini). Using both techniques it was possible to demonstrate a significant increase in platelet adhesiveness in the diabetic pa...

journal_title：Journal of clinical pathology

authors： Shaw S,Pegrum GD,Wolff S,Ashton WL

更新日期：1967-11-01 00:00:00

abstract：AIMS:To evaluate an indirect immunofluorescence flow cytometry technique in a series of patients with large fetomaternal haemorrhage (FMH). METHODS:Patient samples identified by Kleihauer testing in local laboratories as having FMH > 4 ml were sent for flow cytometric analysis. In a proportion of cases the mothers rec...

journal_title：Journal of clinical pathology

authors： Johnson PR,Tait RC,Austin EB,Shwe KH,Lee D

更新日期：1995-11-01 00:00:00

abstract：:A case of chromoblastomycosis confined to the mucous membrane of one side of the nasal septum is reported. The organism was not cultivated, but its characteristics in histological preparations were typical of those of the organisms in sections of cutaneous lesions known to be caused by Phialophora pedrosoi and related...

journal_title：Journal of clinical pathology

authors： SYMMERS WS

更新日期：1960-07-01 00:00:00

abstract：AIMS:To evaluate the influence of involvement of the peritoneal surface by carcinoma of the rectum on local recurrence and prognosis. METHODS:Prospective analysis of pathological prognostic factors in 209 resections for rectal carcinoma between 1988 and 1993 with meticulous pathological technique particularly to asses...

journal_title：Journal of clinical pathology

authors： Shepherd NA,Baxter KJ,Love SB

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND:Microscopic examination of scalp hair can provide important diagnostic information in a range of paediatric conditions. It is a non-invasive and cost effective investigation, which is not widely performed. AIMS:To examine retrospectively the value of hair examination by light microscopy, including polarisin...

journal_title：Journal of clinical pathology

authors： Smith VV,Anderson G,Malone M,Sebire NJ

更新日期：2005-12-01 00:00:00

abstract：:Lymphoid tissue of the endometrium was analysed by histological, immunohistological, and electron microscopical methods in 10 healthy uteri. A panel of monoclonal antibodies recognising macrophages (OKMI), HLA-DR antigen, B lymphocytes, T lymphocytes and their subsets, and dendritic reticulum cells was used in a two s...

journal_title：Journal of clinical pathology

authors： Morris H,Edwards J,Tiltman A,Emms M

更新日期：1985-06-01 00:00:00

abstract：AIMS:To assess the accuracy of the Mast-ID 15 system compared with API 20 E for the identification of stock and fresh clinical strains of Enterobacteriaceae and Acinetobacter spp; to compare the accuracy of 19 pin and 36 pin multipoint inoculator heads. METHODS:One hundred frozen stock cultures of Enterobacteriaceae a...

journal_title：Journal of clinical pathology

authors： Shakespeare AP,Megson GM,Jones PA,Drucker DB,Keaney MG,Ganguli LA

更新日期：1992-02-01 00:00:00

abstract：:Neoplastic and non-neoplastic oxyphil cells in thyroid disorders were investigated for enzyme and synthetic activity, ultrastructural features, and immune complex deposition. A reduced but definite content of thyroglobuliin and similar enzyme profiles and ultrastructural features in all types of oxyphill change were f...

journal_title：Journal of clinical pathology

authors： Kendall CH,McCluskey E,Meagles JN

更新日期：1986-08-01 00:00:00

abstract：:Campylobacter pyloridis is a spiral bacterium which was seen by histopathologists several years before it was cultured in 1982 in Perth, Western Australia. It has unique cellular fatty acids, predominantly tetradecanoic acid and cis-11, 12 methylene octadecanoic acid. It also has a unique ultrastructure which is diffe...

journal_title：Journal of clinical pathology

authors： Goodwin CS,Armstrong JA,Marshall BJ

更新日期：1986-04-01 00:00:00

abstract：AIMS:To determine the sensitivity and specificity of a multiplex PCR assay for the contemporary identification of major species involved in oral candidiasis, without extraction and purification of DNA from the samples under investigation; and evaluation of this method in comparison with routine phenotypic culture ident...

journal_title：Journal of clinical pathology

authors： Liguori G,Lucariello A,Colella G,De Luca A,Marinelli P

更新日期：2007-09-01 00:00:00

abstract：:A comparison of Skirrow's, Butzler's, Blaser's, Campy-BAP and Preston media for Campylobacter spp was made using human, animal and environmental specimens. Butzler's medium gave the lowest isolation rate and Preston medium, which was the most selective, the highest isolation rate. Enrichment culture using Preston enri...

journal_title：Journal of clinical pathology

authors： Bolton FJ,Coates D,Hinchliffe PM,Robertson L

更新日期：1983-01-01 00:00:00

abstract：:Eight isolates of C. albicans were used to determine the frequency with which germ tube formation occurred: on rice extract -Tween 80 agar, on its components, and on 1% bactopeptone agar after three hr at 37 degrees C; in 0.5% aqueous solution of various carbohydrates; in various concentrations of glucose; on 0.5 and ...

journal_title：Journal of clinical pathology

authors： Joshi KR,Bremner DA,Parr DN,Gavin JB

更新日期：1975-01-01 00:00:00

abstract：AIMS:To determine the causes of death in patients with osteogenesis imperfecta, excluding infants with the perinatal lethal form (type II). METHODS:Seventy nine patients with known osteogenesis imperfecta were identified, 37 of whom had been seen clinically in life. Causes of death were identified from death certifica...

journal_title：Journal of clinical pathology

authors： McAllion SJ,Paterson CR

更新日期：1996-08-01 00:00:00

abstract：:Fifty-three breast carcinomas were examined by an indirect immunoperoxidase technique for the presence of the alpha-subunit of human chorionic gonadotrophin. Positive staining occurred in 12 (22.6%). There was no correlation between alpha-subunit production and specific histological features, but production was relate...

journal_title：Journal of clinical pathology

authors： Walker RA

更新日期：1978-03-01 00:00:00

abstract：:A latex agglutination test for the detection of Pseudomonas pseudomallei antigen in urine was evaluated for the rapid diagnosis of melioidosis. With unconcentrated urine, antigen was detected in only 18% of patients with melioidosis overall. However, when urine was concentrated 100-fold, antigen was detected in 47% ov...

journal_title：Journal of clinical pathology

authors： Smith MD,Wuthiekanun V,Walsh AL,Teerawattanasook N,Desakorn V,Suputtamongkol Y,Pitt TL,White NJ

更新日期：1995-02-01 00:00:00

abstract：:Two newborn babies with an intact atrial septum are described. In one, the two components of the atrial septum appeared to have become fused after relatively normal initial development; the left side of this heart was hypoplastic. In the other baby the formation of the atrial septum appeared to have been completely an...

journal_title：Journal of clinical pathology

authors： Shortland-Webb WR,Tozer RA,Cameron AH

更新日期：1966-11-01 00:00:00

abstract：:As part of a wider survey of infections and defence mechanisms, concentrations of serum immunoglobulins IgG, IgA, and IgM were measured regularly by single radial immunodiffusion in a group of children receiving treatment for acute lymphoblastic leukaemia while in their first remission. IgM concentrations were often m...

journal_title：Journal of clinical pathology

authors： Reid MM,Craft AW,Cox JR

更新日期：1981-05-01 00:00:00

abstract：:The cardiovascular system is a common target of amyloidosis. This review presents the current clinical and diagnostic approach to amyloidosis, with the emphasis on cardiovascular involvement. It summarises recent nomenclature, classification, and pathogenesis of amyloidosis. In addition, non-invasive possibilities are...

journal_title：Journal of clinical pathology

authors： Kholová I,Niessen HW

更新日期：2005-02-01 00:00:00