Latex agglutination for rapid detection of Pseudomonas pseudomallei antigen in urine of patients with melioidosis.

Abstract:

:A latex agglutination test for the detection of Pseudomonas pseudomallei antigen in urine was evaluated for the rapid diagnosis of melioidosis. With unconcentrated urine, antigen was detected in only 18% of patients with melioidosis overall. However, when urine was concentrated 100-fold, antigen was detected in 47% overall and in 67% of patients with septicaemia or disseminated infection, in whom a rapid diagnosis is most important. The specificity of the test was 100%. These results compared favourably with an enzyme immunoassay. This latex agglutination test is a simple, rapid and highly specific method of diagnosing melioidosis, and will be particularly useful in areas with limited laboratory facilities.

journal_name

J Clin Pathol

authors

Smith MD,Wuthiekanun V,Walsh AL,Teerawattanasook N,Desakorn V,Suputtamongkol Y,Pitt TL,White NJ

doi

10.1136/jcp.48.2.174

subject

Has Abstract

pub_date

1995-02-01 00:00:00

pages

174-6

issue

2

eissn

0021-9746

issn

1472-4146

journal_volume

48

pub_type

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