Immunohistochemical demonstration of neurone specific enolase in bone marrow infiltrated by neuroblastoma.

abstract：:Platelet transfusions have the highest incidence of post-transfusion sepsis compared with any other blood products. Recent reports suggest that platelet-related bacteraemia occurs at a frequency of approximately 50 times greater than that for red blood cells. The source is usually skin contaminants from the donor and ...

journal_title：Journal of clinical pathology

authors： Coutinho H,Galloway A,Ajdukiewicz K,Cleeve V

更新日期：2010-03-01 00:00:00

abstract：:The effect of the new beta-lactam antibiotic FL 1060 on urinary tract pathogens, of which 71 were sensitive to and 100 resistant to ampicillin, is presented here. When tested by conventional methods FL 1060 was found to be highly active against ampicillin-sensitive strains of E. coli but phenotypically resistant varia...

journal_title：Journal of clinical pathology

authors： Greenwood D,Brooks HL,Gargan R,O'Grady F

更新日期：1974-03-01 00:00:00

abstract：:The adhesion molecule E-cadherin is essential for maintaining epithelial intercellular adhesion. Loss or reduced expression of E-cadherin has been related to invasive behaviour in a wide range of carcinomas. Using immunoblotting techniques, the existence of multiple soluble forms of E-cadherin was demonstrated in urin...

journal_title：Journal of clinical pathology

authors： Banks RE,Porter WH,Whelan P,Smith PH,Selby PJ

更新日期：1995-02-01 00:00:00

abstract：AIMS:To institute recommendations from a laboratory turnround time study; to evaluate audit methods; and to quantify improvements achieved. METHODS:Changes to result report distribution and specimen delivery were affected by posting results directly from the laboratory followed by the introduction of a twice daily cou...

journal_title：Journal of clinical pathology

authors： Smellie WS,Galloway PJ,Johnston JI

更新日期：1995-04-01 00:00:00

abstract：:The distribution and quantitative expression of HBcAg in relation to serum HBeAg and liver histology before and after a trial of interferon in 50 patients with chronic type B hepatitis were evaluated using polyclonal and monoclonal antibodies. In general, both antisera showed a similar pattern in terms of the distribu...

journal_title：Journal of clinical pathology

authors： Chu CM,Lin SM,Liaw YF

更新日期：1991-01-01 00:00:00

abstract：:Two hundred and forty-seven strains of micro-organisms were isolated from the urinary tract of 121 patients with neurological complaints leading to paraplegia. The commonest infecting organism was E. coli and the commonest type of Proteus was P. mirabilis. Infections with more than one type of organism were present in...

journal_title：Journal of clinical pathology

authors： SCOTT TG

更新日期：1960-01-01 00:00:00

abstract：:Six patients in the neurosurgical ward of Fukushima Medical College Hospital suffering from ventriculitis due to Achromobacter xylosoxidans infection had undergone craniotomy or cranial trepanation before the infection. The strains of A. xylosoxidans isolated from the patients were resistant to streptomycin, ampicilli...

journal_title：Journal of clinical pathology

authors： Shigeta S,Yasunaga Y,Honzumi K,Okamura H,Kumata R,Endo S

更新日期：1978-02-01 00:00:00

abstract：:Pathology review of gynaecological cancer specimens is often carried out as part of the working of gynaecological oncology multidisciplinary team meetings. This review describes the author's experience regarding the most common issues identified during this process. Ten subjects are covered; these range from histopath...

journal_title：Journal of clinical pathology

authors： McCluggage WG

更新日期：2012-04-01 00:00:00

abstract：AIMS:Hypomethylating agents (HMAs) exhibit clinical efficacy in patients with myelodysplastic syndromes (MDS) and myelodysplastic/myeloproliferative neoplasms (MDS/MPN). This study was performed to assess residual disease status by flow cytometry immunophenotyping (FCI) methods in patients with MDS or MDS/MPN treated w...

journal_title：Journal of clinical pathology

authors： Huang L,Garcia-Manero G,Jabbour E,Goswami M,Routbort MJ,Medeiros LJ,Jorgensen JL,Wang SA

更新日期：2016-04-15 00:00:00

abstract：:The effect of temperature, time of storage, and presence of air bubbles in specimens for blood gas analysis was studied. The results show that air bubbles in a 10% proportion are undesirable because of significant elevation in the PO2, and the storage of anaerobic blood samples at room temperature (25 degrees C) is ac...

journal_title：Journal of clinical pathology

authors： Madiedo G,Sciacca R,Hause L

更新日期：1980-09-01 00:00:00

abstract：:Targeted next-generation sequencing using the 50-gene Ion AmpliSeq Cancer Hotspot Panel v2 identified two significant point mutations in endometrial stromal sarcomas (ESS). Case 1 is a uterine mass from a quadragenarian woman with a karyotype lacking any known ESS rearrangements but demonstrated to have a CTNNB1-activ...

journal_title：Journal of clinical pathology

authors： Patel SB,McCormack C,Hodge JC

更新日期：2020-12-01 00:00:00

abstract：AIMS:Marked thrombocytosis is uncommon in chronic myelogenous leukaemia (CML) but may be associated with mutation of JAK2 V617F, calreticulin (CALR) and/or phospho-STAT5 (p-STAT5) activation in other myeloproliferative neoplasms (MPNs), particularly essential thrombocythaemia (ET). We investigated the JAK2 V617F, CALR ...

journal_title：Journal of clinical pathology

authors： Turakhia SK,Murugesan G,Cotta CV,Theil KS

更新日期：2016-08-01 00:00:00

abstract：:This is a retrospective study of the results of 4,642 blood cultures taken from 2,190 patients from 1960 to 1967 in one London hospital. The results suggested that an increased incidence of bacteraemias at this particular hospital was mainly due to the increase in the number of patients having blood cultures. Some of ...

journal_title：Journal of clinical pathology

authors： Crowley N

更新日期：1970-03-01 00:00:00

abstract：:A 60 year old woman affected by Hashimoto's thyroiditis presented with a history of recurring episodes of urticaria and angio-oedema. Clinical and laboratory evaluation of the patient excluded allergy to external agents, hereditary angio-oedema, and occult infections. A pathogenic relation between Hashimoto's thyroidi...

journal_title：Journal of clinical pathology

authors： Amoroso A,Garzia P,Pasquarelli C,Sportelli G,Afeltra A

更新日期：1997-03-01 00:00:00

abstract：:The degree of inflammation in the trachea, bronchi, and lungs of 139 cot deaths has been analysed and each case allocated to one of four groups. In group I the changes were considered to be serious enough to have caused death, while group II cases showed similar abnormalities but of a less severe nature, and in this g...

journal_title：Journal of clinical pathology

authors： Tapp E,Jones DM,Tobin JO

更新日期：1975-11-01 00:00:00

abstract：AIMS:To study the homozygous deletion and methylation status of the 5' CpG island of the p16 and p15 genes (9p21) in a set of primary advanced head and neck squamous cell carcinomas (SCC) and to test whether inactivation of these genes by these mechanisms contributes to head and neck SCC development. METHODS:DNA was e...

journal_title：Journal of clinical pathology

authors： González MV,Pello MF,López-Larrea C,Suárez C,Menéndez MJ,Coto E

更新日期：1997-06-01 00:00:00

abstract：AIMS:To compare the efficacy of and tolerance to oral fluconazole and intraconazole in preventing fungal infection in neutropenic patients with haematological malignancies. PATIENTS:213 consecutive, afebrile adult patients treated with or without autologous stem cell transplantation for haematological malignancies. M...

journal_title：Journal of clinical pathology

authors： Huijgens PC,Simoons-Smit AM,van Loenen AC,Prooy E,van Tinteren H,Ossenkoppele GJ,Jonkhoff AR

更新日期：1999-05-01 00:00:00

abstract：AIMS:The probabilistic approach is widely adopted for breast fine needle aspiration cytology. However, a definite cytological diagnosis is not always possible for C3 (atypia) cases, which poses a management dilemma as this represents a mixed category of benign and malignant cases. It would be beneficial to be able to p...

journal_title：Journal of clinical pathology

authors： Yu SN,Li J,Wong SI,Tsang JYS,Ni YB,Chen J,Tse GM

更新日期：2017-12-01 00:00:00

abstract：:The morphological classification and diagnosis of bladder neoplasms is summarised, with specific focus on histological typing, grading and staging. Four diagnostic categories are described on the basis of the pattern of growth of the urothelial lesions and tumours (flat, exophytic or papillary, endophytic, and invasiv...

journal_title：Journal of clinical pathology

authors： Montironi R,Mazzucchelli R,Scarpelli M,Lopez-Beltran A,Cheng L

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Breast-conserving surgery currently focuses on improving margin clearance and excision volume, the main pathology report parameters for oncological and cosmetic outcomes. AIM:To quantitatively evaluate discrepancies in surgical and pathological estimates of breast specimen sizes, including the influence of ...

journal_title：Journal of clinical pathology

authors： Krekel NM,van Slooten HJ,Barbé E,de Lange de Klerk ES,Meijer S,van den Tol MP

更新日期：2012-03-01 00:00:00

abstract：:The applicability of a hapten-antihapten sandwich technique incorporating a monoclonal antihapten bridge antibody to localisation of tissue antigen is described. The results show that the method is both versatile and selective and has the potential of being even more sensitive than currently used immunoperoxidase meth...

journal_title：Journal of clinical pathology

authors： Jasani B,Thomas DW,Williams ED

更新日期：1981-09-01 00:00:00

abstract：:A radial immunodiffusion technique has been used to measure levels of four serum proteins in preeclampsia with or without proteinuria and in normal pregnant and non-pregnant controls. In preeclampsia unaccompanied by proteinuria, albumin and transferrin levels are similar to those found in the normal pregnant controls...

journal_title：Journal of clinical pathology

authors： Horne CH,Howie PW,Goudie RB

更新日期：1970-09-01 00:00:00

abstract：:The test is an application of the method originally described by Boyden (1951) and adapted by Stavitsky and Arquilla (1958). Sera which contain anti-Panton-Valentine leucocidin agglutinate the prepared red cells, often to a very high dilution, and this has provided a useful serological test for the diagnosis of staphy...

journal_title：Journal of clinical pathology

authors： TOWERS AG

更新日期：1961-03-01 00:00:00

abstract：AIMS:To assess the incidence of nocardia infection over 15 years in a tertiary care hospital. METHODS:Over a 15 year period, Nocardia spp were isolated from 20 patients hospitalised at the Geneva University Hospitals, Switzerland. RESULTS:Sixteen patients had one or more underlying conditions. The median time between...

journal_title：Journal of clinical pathology

authors： Matulionyte R,Rohner P,Uçkay I,Lew D,Garbino J

更新日期：2004-08-01 00:00:00

abstract：:A polyclonal antiserum, produced in sheep and reactive against purified human leucocyte elastase, has been applied to paraffin sections from a range of human tissues by means of the indirect immunoperoxidase method. Striking and consistent results have been obtained. Normal or inflammatory granulocytes were intensely ...

journal_title：Journal of clinical pathology

authors： Crocker J,Jenkins R,Burnett D

更新日期：1984-10-01 00:00:00

abstract：BACKGROUND/AIMS:A twofold increased risk for breast cancer has been reported recently for women with late onset diabetes. Most studies showed that there were differences in serum concentrations of insulin-like growth factors and related proteins between women with and without diabetes who have breast cancer. This study...

journal_title：Journal of clinical pathology

authors： Nardon E,Buda I,Stanta G,Buratti E,Fonda M,Cattin L

更新日期：2003-08-01 00:00:00

abstract：:A biological method for detecting streptococcal nicotinamide adenine dinucleotide glycohydrolase (NADG) is presented, based on its ability to inhibit the growth of Haemophilus parainfluenzae. Three hundred clinical isolates of beta-haemolytic streptococci were tested. All isolates producing NADG belonged to Lancefield...

journal_title：Journal of clinical pathology

authors： Green NE

更新日期：1979-06-01 00:00:00

abstract：:In-vivo studies of fibrinogen metabolism were carried out using an I-120 labelled preparation of fibrinogen supplied commercially by the Radiochemical Centre, Amerhsham for use in the diagnosis of deep venous thrombosis. These studies show that the material is suitable for obtaining the main metabolic parameters of c...

journal_title：Journal of clinical pathology

authors： Bradley J,Hickman JA

更新日期：1975-06-01 00:00:00

abstract：:Eosinophil polymorphonuclear leucocytes (polymorphs) were counted in 45 specimens from patients with Hodgkin's disease and five specimens from patients with reactive follicular hyperplasia. The use of chlorazol fast pink BK, a little known stain for eosinophil polymorphs, combined with image analysis facilitated rapid...

journal_title：Journal of clinical pathology

authors： Fuggle WJ,Crocker J,Smith PJ

更新日期：1984-03-01 00:00:00

abstract：AIMS:Accurate assessment of HER2 status is essential for selection of patients for HER2-targeted treatment such as trastuzumab. This study investigated the hypothesis that delayed fixation impairs HER2 assessment. METHODS:9 carcinomas were received fresh, and samples were fixed immediately or put in fixative at time i...

journal_title：Journal of clinical pathology

authors： Lee AH,Key HP,Bell JA,Kumah P,Hodi Z,Ellis IO

更新日期：2014-07-01 00:00:00