Juvenile polyposis of the stomach: clinicopathological features and its malignant potential.

abstract：AIMS:To investigate how the biopsy Gleason score (GS) and the clinical risk classification have been changed by the reporting rules. METHODS:565 prostate biopsy specimens were reassessed. Each Gleason pattern, 1 to 5, was interpreted according to the modified Gleason grading system proposed by the International Societ...

journal_title：Journal of clinical pathology

authors： Kuroiwa K,Uchino H,Yokomizo A,Naito S

更新日期：2009-03-01 00:00:00

abstract：AIMS:The cell block technique for assessing endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) specimens from pancreatic mucinous cystic lesions (MCLs) was systematically evaluated for the first time, including comparisons with three traditional methods of assessing such specimens. METHODS:The prospective a...

journal_title：Journal of clinical pathology

authors： Wong NACS,Gwiti P,Murigu T,Melegh Z,Beavers S,Gordon F,Alexandridis E,Norton S

更新日期：2020-02-01 00:00:00

abstract：:Pathological findings are described in four cases of a new aminoaciduria in which homocystine is excreted in the urine. All the patients were mentally retarded children. Three of them presented diagnostic features of Marfan's syndrome. Necropsy on one case and biopsy findings in the others are described. Fatty change ...

journal_title：Journal of clinical pathology

authors： GIBSON JB,CARSON NA,NEILL DW

更新日期：1964-07-01 00:00:00

abstract：BACKGROUND:The "classical" antineutrophil cytoplasmic antibody (C-ANCA) pattern seen on indirect immunofluorescence (IIF) is characterised by granular cytoplasmic staining showing central or interlobular accentuation, and is strongly associated with antiproteinase-3 antibodies (PR3-ANCA) and Wegener's granulomatosis. H...

journal_title：Journal of clinical pathology

authors： Wong RC,Silvestrini RA,Savige JA,Fulcher DA,Benson EM

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND:Peutz-Jeghers syndrome (PJS) is an autosomal dominant hamartomatous polyposis syndrome of the gastrointestinal tract, caused by a germline STK11/LKB1 mutation. Nasal polyposis was described in the original report by Peutz. Recently, a molecular-genetic association between nasal polyposis and PJS has been rep...

journal_title：Journal of clinical pathology

authors： de Leng WW,Westerman AM,Weterman MA,Jansen M,van Dekken H,Giardiello FM,de Rooij FW,Paul Wilson JH,Offerhaus GJ,Keller JJ

更新日期：2007-04-01 00:00:00

abstract：AIMS:Sinusoidal dilatation and congestion (SDC) in liver biopsy may be obstructive (due to venous outflow impairment) or non-obstructive in nature. The significance of this finding in the post-liver transplant setting remains unexplored. METHODS:We herein retrospectively analysed all post-transplant liver biopsies sho...

journal_title：Journal of clinical pathology

authors： Bakshi N,Rastogi A,Pamecha V,Bihari C

更新日期：2020-08-24 00:00:00

abstract：:The peripheral lymphocytes of 50 cases of human immunodeficiency virus (HIV) infection (13 of acquired immune deficiency syndrome (AIDS), 17 of AIDS related complex (ARC), and 20 healthy carriers) were studied immunoultrastructurally. The prevalence of "tubuloreticular structures" and "tubular confronting cisternae" i...

journal_title：Journal of clinical pathology

authors： Feremans WW,Huygen K,Menu R,Farber CM,de Caluwe JP,van Vooren JP,Marcelis L,Andre L,Brasseur M,Bondue H

更新日期：1988-01-01 00:00:00

abstract：:Three adults with alpha 1-antitrypsin deficiency are described. In two of the cases the deficiency was genetically determined (cases 1 and 2), and each demonstrated unusual features of the disease. The liver in case 1 (homozygous) showed cholangiolar hyperplasia which has been recorded only once before. Case 2 (hetero...

journal_title：Journal of clinical pathology

authors： Sweeney EC

更新日期：1975-08-01 00:00:00

abstract：AIMS:The Royal College of Pathologists recommend that a median of at least 12 lymph nodes should be harvested during pathological staging of colorectal cancer. It is not always easy to harvest the required number, especially in patients with rectal cancer receiving neoadjuvant therapy. Lymph node revealing solutions, f...

journal_title：Journal of clinical pathology

authors： Horne J,Carr NJ,Bateman AC,Kandala N 2nd,Adams J,Silva S,Ryder I

更新日期：2016-06-01 00:00:00

abstract：:A patient with chronic granulomatous disease who was being treated with steroids was diagnosed with a soft tissue Scedosporium apiospermum infection. Despite extensive treatment with antifungals progression to involve solid tissue (bone) occurred. Treatment required an HLA matched bone marrow transplant, which led to ...

journal_title：Journal of clinical pathology

authors： Gompels MM,Bethune CA,Jackson G,Spickett GP

更新日期：2002-10-01 00:00:00

abstract：:Advanced non-small cell lung cancer samples are tested for epidermal growth factor receptor (EGFR) gene mutations. Their detection by direct sequencing is time-consuming. Conversely, the length analysis of fluorescently labelled PCR products is easier. To avoid labelled primers and the automated capillary electrophore...

journal_title：Journal of clinical pathology

authors： Malapelle U,Russo S,Pepe F,Sgariglia R,De Luca C,Bellevicine C,Pallante P,Troncone G

更新日期：2013-11-01 00:00:00

abstract：:Large cell neuroendocrine carcinoma (LCNEC) is a high grade type of neuroendocrine tumour with an aggressive clinical course. This report describes the first case of LCNEC combined with an adenocarcinoma component in the common bile duct. A 68 year old man presented with jaundice. Severe stenosis of the bile duct was ...

journal_title：Journal of clinical pathology

authors： Sato K,Waseda R,Tatsuzawa Y,Fujinaga H,Wakabayashi T,Ueda Y,Katsuda S

更新日期：2006-01-01 00:00:00

abstract：:The excretion of 2,3-dinor-6-keto prostaglandin F1 alpha, a major urinary metabolite of prostacyclin, and the formation of thromboxane B2, a stable metabolite of thromboxane A2, by platelets stimulated by adenosine diphosphate, were studied in alcoholics, who had been admitted for detoxification. Once prolonged heavy ...

journal_title：Journal of clinical pathology

authors： Neiman J,Hillbom M,Benthin G,Anggård EE

更新日期：1987-05-01 00:00:00

abstract：BACKGROUND:Oncogenicity of human papillomavirus (HPV) DNA in premalignant and malignant uterine cervical diseases is mainly induced by E6/E7 open reading frame (ORF). The presence of an oncogenic HPV DNA may be a diagnostic marker for the detection of cytologically negative smears. AIMS:To evaluate an original polymer...

journal_title：Journal of clinical pathology

authors： Clavel C,Rihet S,Masure M,Chypre C,Boulanger JC,Quereux C,Birembaut P

更新日期：1998-01-01 00:00:00

abstract：:Fluorescence in situ hybridisation (FISH) analysis is now widely employed in the diagnosis and risk stratification of a wide range of malignant diseases. While this technique is used successfully with formalin-fixed paraffin-embedded (FFPE) sections from numerous tissue types, FISH analysis of FFPE tissue sections fro...

journal_title：Journal of clinical pathology

authors： Neat MJ,Moonim MT,Dunn RG,Geoghegan H,Foot NJ

更新日期：2013-01-01 00:00:00

abstract：AIM:We examined the genetic alterations in a mother and son with multiple eosinophilic chromophobe renal cell carcinomas (chRCCs) showing no other features. METHODS:Germline DNA and bilateral renal cell carcinoma DNA were genetically analysed by whole-exome sequencing. Candidate gene alterations in the first patient's...

journal_title：Journal of clinical pathology

authors： Sakamoto H,Yamasaki T,Sumiyoshi T,Utsunomiya N,Takeda M,Kamba T,Nakamura E,Ogawa O

更新日期：2018-10-01 00:00:00

abstract：:The prevalence of Helicobacter pylori infection in patients with Barrett's oesophagus was studied prospectively. A sensitive immunohistochemical staining of H pylori was performed in oesophageal and gastric biopsies of 73 patients from a surveillance group with this condition. H pylori was detected in 11 cases of Barr...

journal_title：Journal of clinical pathology

authors： Ricaurte O,Fléjou JF,Vissuzaine C,Goldfain D,Rotenberg A,Cadiot G,Potet F

更新日期：1996-02-01 00:00:00

abstract：AIM:Heart failure (HF) affects millions of older individuals in both developed and low/middle-income countries. Serum galectin-3 levels have been shown to have prognostic value. However, its use as a diagnostic biomarker has not been explored. The aim was to establish a saliva galectin-3 reference range and to demonstr...

journal_title：Journal of clinical pathology

authors： Zhang X,Wan Y,Chata R,Brazzale A,Atherton JJ,Kostner K,Dimeski G,Punyadeera C

更新日期：2016-12-01 00:00:00

abstract：:A moderatley sensitive, rapid, and economical test scheme for the detection of infantile gastroenteritis virus (IGV) in stool or antibody in serum has been developed and evaluated. The test scheme with minor modifications was an adaptation of a counter-immunoelectro-osmophoresis system we once used for the detection o...

journal_title：Journal of clinical pathology

authors： Middleton PJ,Petric M,Hewitt CM,Szymanski MT,Tam JS

更新日期：1976-03-01 00:00:00

abstract：AIMS:To determine whether Ki-67 immunoexpression in penile squamous cell carcinoma (PSCC) has a prognostic value and correlates with lymph node metastasis, human papillomavirus (HPV) infection and patient survival. METHODS:148 formalin-fixed paraffin-embedded PSCC samples were tissue-microarrayed, including 97 usual-t...

journal_title：Journal of clinical pathology

authors： Stankiewicz E,Ng M,Cuzick J,Mesher D,Watkin N,Lam W,Corbishley C,Berney DM

更新日期：2012-06-01 00:00:00

abstract：:Inhibition of streptolysin O activity by cholesterol depends on the latter being in free form. The normal esterified and protein-bound cholesterol fractions in serum do not influence streptolysin O activity. However, high cholesterol levels in rabbits fed cholesterol with cholic acid were associated with an increased ...

journal_title：Journal of clinical pathology

authors： Watson KC,Rose TP,Kerr EJ

更新日期：1972-10-01 00:00:00

abstract：AIMS:The IHC4+C score combines assessment of oestrogen receptor (ER), progesterone receptor (PgR), HER2 and Ki67 with clinicopathological parameters to identify the risk of distant disease recurrence in patients with breast cancer, so, aiding treatment decision-making on adjuvant chemotherapy. Despite low cost and wide...

journal_title：Journal of clinical pathology

authors： Dodson A,Zabaglo L,Yeo B,Miller K,Smith I,Dowsett M

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Epidermal growth factor receptor (EGFR) gene mutation at the kinase domain and EGFR gene amplification are reported to be predictors of the response to EGFR tyrosine kinase inhibitors in lung cancer cases. In malignant mesothelioma (MM), the role of EGFR is less clear. METHODS:Thirty-eight MM specimens were...

journal_title：Journal of clinical pathology

authors： Enomoto Y,Kasai T,Takeda M,Takano M,Morita K,Kadota E,Iizuka N,Maruyama H,Haratake J,Kojima Y,Ikeda N,Inatsugi N,Nonomura A

更新日期：2012-06-01 00:00:00

abstract：:Mallory bodies were isolated from necropsy livers from patients with alcoholic hepatitis with and without cirrhosis with a Ficoll viscosity barrier. The purity of Mallory bodies in the isolate varied between 70 and 90%, estimated by counting Mallory bodies and non-Mallory body structures in haematoxylin-eosin stained ...

journal_title：Journal of clinical pathology

authors： Gluud C,Hardt F,Aldershvile J,Christoffersen P,Lyon H,Nielsen J

更新日期：1981-09-01 00:00:00

abstract：BACKGROUND:Epstein's syndrome is defined as a subtype of Alport's syndrome, and is distinguished from the other subtypes by accompanying macrothrombocytopenia. Mutations in collagen IV genes are known to be involved in the pathogenesis of typical Alport's syndrome. However, the presence of an underlying genetic defect ...

journal_title：Journal of clinical pathology

authors： Naito I,Nomura S,Inoue S,Kagawa M,Kawai S,Gunshin Y,Joh K,Tsukidate C,Sado Y,Osawa G

更新日期：1997-11-01 00:00:00

abstract：:Methods for detecting insulin binding or transporting antibodies are described, involving the use of radioactively labelled insulin (insulin (131)I). These antibodies are detected in a high proportion of patients receiving insulin, particularly those requiring large doses. The protein fractions concerned appear to be ...

journal_title：Journal of clinical pathology

authors： HARRIS-JONES JN,MILLER H,OWEN G

更新日期：1963-03-01 00:00:00

abstract：AIM:Thalassaemia is a good candidate disease for control by preventive genetic programmes in developing countries. Accurate population frequency data are needed for planning the control of thalassaemia in the high risk Guangdong Province of southern China. METHODS:In total, 13397 consecutive samples from five geograph...

journal_title：Journal of clinical pathology

authors： Xu XM,Zhou YQ,Luo GX,Liao C,Zhou M,Chen PY,Lu JP,Jia SQ,Xiao GF,Shen X,Li J,Chen HP,Xia YY,Wen YX,Mo QH,Li WD,Li YY,Zhuo LW,Wang ZQ,Chen YJ,Qin CH,Zhong M

更新日期：2004-05-01 00:00:00

abstract：:An inhibitor of plasminogen activator has been identified in human platelets by the technique of sodium dodecyl sulphate polyacrylamide gel electrophoresis and zymography. The inhibitor has a molecular weight of about 40 000 and is distinct from known plasma protease inhibitors. It is associated almost exclusively wit...

journal_title：Journal of clinical pathology

authors： Booth NA,Anderson JA,Bennett B

更新日期：1985-07-01 00:00:00

abstract：:The indirect immunofluorescence technique was used to study the expression of the blood group A and H antigens in fresh-frozen and formalin-fixed paraffin-embedded sections of the bladder mucosa of 21 patients with non-neoplastic diseases of the bladder. Reliable assessment of these antigens could only be made using c...

journal_title：Journal of clinical pathology

authors： Thorpe SJ,Abel P,Slavin G,Feizi T

更新日期：1983-08-01 00:00:00

abstract：:A method for accurately counting platelets is described using the Coulter counter model B fitted with a standard 100mu aperture tube. This enables the counter to be used for red and white cell as well as platelet counts using the same aperture tube. The method uses standard equipment except for a small inexpensive ele...

journal_title：Journal of clinical pathology

authors： Davis RE,Green RE

更新日期：1967-09-01 00:00:00