Abstract:
:The incidence of placenta accreta, defined as the abnormal adherence of the placenta to the uterine wall, has been increasing alarmingly in the developed as well as the developing world. There is considerable maternal morbidity and mortality related to the condition. The pathophysiology focuses on the balance between decidualisation on the one hand and trophoblast invasion on the other. Pathological diagnosis relies on the finding of placental villi in direct apposition to myometrium, either in hysterectomy specimens or in placental basal plates.
journal_name
J Clin Patholjournal_title
Journal of clinical pathologyauthors
Khong TYdoi
10.1136/jcp.2008.055202subject
Has Abstractpub_date
2008-12-01 00:00:00pages
1243-6issue
12eissn
0021-9746issn
1472-4146pii
jcp.2008.055202journal_volume
61pub_type
杂志文章,评审abstract::A study has been made of 523 strains of staphylococci on the basis of biological properties, phage typing, and serology. The value of serology in the identification of pathogenic staphylococci has been assessed. ...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.23.4.370
更新日期:1970-05-01 00:00:00
abstract::Angiogenesis plays a crucial role in melanoma metastasis and progression. In recent years, numerous studies have investigated the prognostic and clinical significance of this phenomenon, and the development of molecular techniques has enabled us to achieve a better understanding of angiogenesis in melanoma. Herein, we...
journal_title:Journal of clinical pathology
pub_type: 杂志文章,评审
doi:10.1136/jclinpath-2015-203482
更新日期:2016-06-01 00:00:00
abstract::Morphometric techniques were applied to cytocentrifuge smears from 27 patients with histologically confirmed follicular non-Hodgkin's lymphoma to determine the usefulness of this method in diagnosis. Analysis of quantitative data confirmed that most subtypes were classified correctly on the basis of the proportion of ...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.41.4.370
更新日期:1988-04-01 00:00:00
abstract::Five cases of inflammatory pseudotumour of the liver are reported and compared with seven individual previously published case reports. Clinical presentation was variable but often comprised low grade intermittent fever, vague abdominal symptoms, and a history of weight loss. Leucocytosis, raised erythrocyte sedimenta...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.39.7.761
更新日期:1986-07-01 00:00:00
abstract::Two diabetic patients with symptomatic urinary tract infection by Torulopsis glabrata were successfully treated with two-week courses of 5-fluorocytosine. ...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.27.1.50
更新日期:1974-01-01 00:00:00
abstract:OBJECTIVE:We explore factors such as the blood sampling site (capillary vs venous), the equipment (HemoCue vs automated haematology analyser) and the model of the HemoCue device (201+ vs 301) that may impact haemoglobin measurements in capillary and venous blood. METHODS:Eleven studies were identified, and bias, conco...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jclinpath-2020-206717
更新日期:2020-10-06 00:00:00
abstract::Human papillomavirus antigen was found in 39 (16%) of 253 colposcopic biopsies from a group of women at high risk for cervical cancer who had been examined in the early 1970s. Immunohistochemical evidence of papillomavirus infection was found in 20 (30%) of 67 cervical intraepithelial neoplasia lesions infected with w...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.38.8.855
更新日期:1985-08-01 00:00:00
abstract:AIMS:To show that medullary carcinomas of the thyroid are morphologically indistinguishable from gut carcinoids: the value of histochemistry in their identification and differential diagnosis from metastatic carcinoid tumours to the thyroid and some follicular cell neoplasms. METHODS:15 thyroid medullary carcinomas wi...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.46.2.113
更新日期:1993-02-01 00:00:00
abstract:AIMS:To investigate the expression of the placental cell-specific associated proteins in infantile haemangioma (IH). METHODS:Immunohistochemical staining was used to investigate the expression of human chorionic gonadotrophin (hCG), human placental lactogen (hPL), human leucocyte antigen-G (HLA-G), cytokeratin 7 (CK7)...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jclinpath-2011-200191
更新日期:2011-10-01 00:00:00
abstract::Mast cells were identified by electronmicroscopy in the alveolar wall of the lung in 20 subjects (10 normal, 10 abnormal). A quantitative and qualitative study was made of the mast cells. In the normal lung there was an average concentration of 350 mast cells/mm2 of alveolar wall and in the abnormal 523/mm2. Mast cell...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.34.12.1333
更新日期:1981-12-01 00:00:00
abstract:AIMS:Apoptosis in prostate cancer was evaluated after three months of combined endocrine therapy to investigate the association with tumour grade, tumour stage, and the immunohistochemical detection of p53 and bcl-2 in tumour cells before and after therapy. METHODS:Twenty six formalin fixed, paraffin wax embedded core...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.50.5.384
更新日期:1997-05-01 00:00:00
abstract:BACKGROUND:A genetic component to the development of chronic fatigue syndrome (CFS) has been proposed, and a possible association between human leucocyte antigen (HLA) class II antigens and chronic fatigue immune dysfunction has been shown in some, but not all, studies. AIMS:To investigate the role of HLA class II ant...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.2004.022681
更新日期:2005-08-01 00:00:00
abstract::A rapid and reproducible technique for in situ hybridisation, using biotin labelled probes for the Y chromosome, human DNA, hepatitis B virus DNA and cytomegalovirus DNA on formalin fixed, paraffin embedded liver tissue, was developed. The degree of proteolytic digestion of tissue specimens is critical to ensure adequ...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.41.7.793
更新日期:1988-07-01 00:00:00
abstract::Two cases of anticonvulsant megaloblastic anaemia are described, showing features of unusual interest. Though both cases were apparently deficient in folic acid, the Figlu tests were negative. One patient had an extremely low serum B(12) concentration apparently associated with defective B(12) absorption due to defici...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.18.5.593
更新日期:1965-09-01 00:00:00
abstract:AIMS:To study the homozygous deletion and methylation status of the 5' CpG island of the p16 and p15 genes (9p21) in a set of primary advanced head and neck squamous cell carcinomas (SCC) and to test whether inactivation of these genes by these mechanisms contributes to head and neck SCC development. METHODS:DNA was e...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.50.6.509
更新日期:1997-06-01 00:00:00
abstract::The laboratory findings in seven cases of endocarditis caused by coagulase-negative staphylococci are presented. The usefulness of biochemical characterization of the strains in diagnosis and the selection of antibiotics for prophylaxis and treatment are discussed. ...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.26.7.517
更新日期:1973-07-01 00:00:00
abstract:BACKGROUND:Friend leukaemia integration-1 (FLI-1) antibody is a useful marker for Ewing's sarcoma/primitive neuroectodermal tumour (EWS/PNET) and vascular tumours. However, it is also expressed in subsets of lymphoblastic lymphoma, Merkel cell carcinoma (MCC) and desmoplastic small round cell tumour (DSRCT). AIM:To de...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.2006.039230
更新日期:2007-06-01 00:00:00
abstract:BACKGROUND:Epidermal growth factor receptor (EGFR) gene mutation at the kinase domain and EGFR gene amplification are reported to be predictors of the response to EGFR tyrosine kinase inhibitors in lung cancer cases. In malignant mesothelioma (MM), the role of EGFR is less clear. METHODS:Thirty-eight MM specimens were...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jclinpath-2011-200631
更新日期:2012-06-01 00:00:00
abstract::Human and chicken blood were snap-frozen as droplets in liquid ntirogen. Storage in the vapour phase liquid nitrogen container for nine months followed by rapid thawing resulted in approximately 10% haemolysis of the red cells. The ability of the thawed red cells to haemagglutinate viruses was unimpaired by the manipu...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.33.1.8
更新日期:1980-01-01 00:00:00
abstract:BACKGROUND:Prognostic factors in predicting outcomes in patients with head and neck squamous-cell carcinoma (HNSCC) are limited to the clinical-pathological parameters, including lymph node metastasis, location, grade and stage of the disease. AIM:To determine whether the expression of these proteins has a value in pr...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.2006.036624
更新日期:2007-02-01 00:00:00
abstract::Four assays for the detection of alphafetoprotein (AFP) in the diagnosis of primary hepatocellular carcinoma (HCC) were evaluated. The frequency of AFP detection was compared in 89 HCC patients and in 71 patients with chronic active hepatitis/cirrhosis. Of the four assays, immunodiffusion, counterimmunoelectrophoresis...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.33.8.792
更新日期:1980-08-01 00:00:00
abstract::Three cases of islet cell necrosis in neonates are reported. The association of this rare condition with antepartum haemorrhage, anoxia, shock and intravascular coagulation are discussed. The clinical and morphological appearances were compared with previous descriptions of this condition and an association with neona...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.40.10.1206
更新日期:1987-10-01 00:00:00
abstract::Hereditary spherocytosis is a relatively common haematological disorder and will be encountered by all haematologists. The abundance of new information, dealing principally with molecular and genetic aspects of pathophysiology, is beginning to have implications for its investigation and management. While these advance...
journal_title:Journal of clinical pathology
pub_type: 杂志文章,评审
doi:10.1136/jcp.44.6.441
更新日期:1991-06-01 00:00:00
abstract:AIMS:To determine whether Ki-67 immunoexpression in penile squamous cell carcinoma (PSCC) has a prognostic value and correlates with lymph node metastasis, human papillomavirus (HPV) infection and patient survival. METHODS:148 formalin-fixed paraffin-embedded PSCC samples were tissue-microarrayed, including 97 usual-t...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jclinpath-2011-200638
更新日期:2012-06-01 00:00:00
abstract:AIM:To determine whether sampling the anterior and posterior cervical lips in hysterectomy specimens provides the best opportunity for detecting unsuspected cervical intraepithelial neoplasia (CIN). METHODS:The frequency with which CIN was identified at a range of positions on the anterior and posterior lips and left ...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.48.4.323
更新日期:1995-04-01 00:00:00
abstract::Serum haptoglobin levels have been studied in patients with a number of haemolytic disorders. In general, serum haptoglobins were low in patients with increased haemolysis. Values were reduced irrespective of whether haemolysis occurred intravascularly or extravascularly. The reduction was related to the amount of hae...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.13.6.478
更新日期:1960-11-01 00:00:00
abstract:BACKGROUND:Thyrotropin-secreting adenomas (TSH-As) are rare and, according to the World Health Organization criteria (WHO 2004), a significant proportion of them present features of atypical adenomas at the time of diagnosis. AIMS:To determine the frequency of "atypical adenomas" and the significance of this definitio...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.2008.061523
更新日期:2009-05-01 00:00:00
abstract::Human sperm heads were detected and tracked using semiautomatic image analysis. Measurements of size and shape on two specimens from each of 26 men showed that the major component of variability both within and between subjects was the number of small elongated sperm heads. Variability of the computed features between...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.39.12.1347
更新日期:1986-12-01 00:00:00
abstract::Three hundred and ninety eight serum samples from 270 human immunodeficiency virus (HIV) antibody positive asymptomatic homosexual men were tested in the Abbott and Dupont HIV antigen ELISA tests. In the Abbott test 62 (16%) of the sera were positive, according to the manufacturer's instructions, compared with 55 (14%...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.43.5.420
更新日期:1990-05-01 00:00:00
abstract::An automated technique is described which is capable of detecting sickle-cell haemoglobin and differentiating the sickle-cell trait from sickle-cell anaemia. The method is based upon the Itano solubility test and utilizes Technicon equipment. ...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.25.4.330
更新日期:1972-04-01 00:00:00