The preparation of 59 Fe-labelled transferrin for ferrokinetic studies.

abstract：:Eosinophil polymorphonuclear leucocytes (polymorphs) were counted in 45 specimens from patients with Hodgkin's disease and five specimens from patients with reactive follicular hyperplasia. The use of chlorazol fast pink BK, a little known stain for eosinophil polymorphs, combined with image analysis facilitated rapid...

journal_title：Journal of clinical pathology

authors： Fuggle WJ,Crocker J,Smith PJ

更新日期：1984-03-01 00:00:00

abstract：AIMS:To evaluate the effect of 10 day triple treatment on H pylori eradication and associated gastritis. METHODS:Fifty patients with H pylori positive non-ulcer dyspepsia were treated for 10 days with amoxicillin, tinidazole, and bismuth salts. Histological examination of the antral mucosa was performed before (T0), s...

journal_title：Journal of clinical pathology

authors： Di Napoli A,Petrino R,Boero M,Bellis D,Chiandussi L

更新日期：1992-09-01 00:00:00

abstract：AIMS:To identify molecular characteristics to hepatitis C virus (HCV)-associated diffuse large B-cell lymphoma (DLBCL) through a comprehensive miRNAs expression profiling. METHODS:In this study, miRNA profiles were obtained from 37 patients with DLBCLs and 60 patients with reactive lymph nodes, equally distributed acc...

journal_title：Journal of clinical pathology

authors： Augello C,Gianelli U,Savi F,Moro A,Bonoldi E,Gambacorta M,Vaira V,Baldini L,Bosari S

更新日期：2014-08-01 00:00:00

abstract：AIMS:To evaluate and compare the long term prognostic value of the WHO classification and the computerised multivariate morphometrical D score in endometrial hyperplasia. To test the reproducibility of the D score in two different centres. METHODS:Histopathological WHO classification and computerised morphometrical an...

journal_title：Journal of clinical pathology

authors： Orbo A,Baak JP,Kleivan I,Lysne S,Prytz PS,Broeckaert MA,Slappendel A,Tichelaar HJ

更新日期：2000-09-01 00:00:00

abstract：:The morphology of the labial salivary glands in subjects with and without cystic fibrosis has been studied by light and electron microscopy. The terms ;light' cell, ;dark' cell, ;clear' cell, and ;myoepithelial' cell are used to describe the four cell types distinguished at the level of the electron microscope. The da...

journal_title：Journal of clinical pathology

authors： Doggett RG,Bentinck B,Harrison GM

更新日期：1971-04-01 00:00:00

abstract：:To assess the pattern and severity of liver disease in patients who had undergone jejuno-ileal bypass for the treatment of morbid obesity, 23 patients were biopsied, all of whom had had intact bypasses for more than 10 years. These were examined by light and electron microscopy. Previous biopsy specimens from each pat...

journal_title：Journal of clinical pathology

authors： Boon AP,Thompson H,Baddeley RM

更新日期：1988-12-01 00:00:00

abstract：:In all cases of primary endocardial fibroelastosis investigated diffuse degenerative changes in the ganglion cells were detected. Thickened endocardium was formed by the proliferation of mesenchymal cells located under the endothelial endocardium and of the mesenchyme surrounding the necrobiotic muscle cells. In some ...

journal_title：Journal of clinical pathology

authors： Zóltowska A

更新日期：1971-04-01 00:00:00

abstract：:Gastrointestinal cell proliferation plays an important role in the maintenance of the integrity of the gastrointestinal system. The study of gastrointestinal proliferation kinetics allows a better understanding of the complexity of the system, and also has important implications for the study of gastrointestinal carci...

journal_title：Journal of clinical pathology

authors： Wong WM,Wright NA

更新日期：1999-05-01 00:00:00

abstract：:The pathological findings of an intradural and extramedullary cyst in the mid cervical spinal canal are described in a 55 year old woman who presented with a short history of pain and paraesthesia of the right arm. Intradural well defined solitary cystic lesions in the spinal canal are uncommon, their pathogenesis is ...

journal_title：Journal of clinical pathology

authors： Wilkinson N,Reid H,Hughes D

更新日期：1992-11-01 00:00:00

abstract：:Human epidermal growth factor receptor 2 (HER2) testing is required for newly diagnosed breast cancer and advised for recurrent and metastatic breast cancer, to determine treatment planning using HER2-directed therapy in the neoadjuvant, adjuvant and advanced disease settings. Wide variation, nationally, in the turnar...

journal_title：Journal of clinical pathology

authors： Shaaban AM,Purdie CA,Bartlett JM,Stein RC,Lane S,Francis A,Thompson AM,Pinder SE,Translational Subgroup of the NCRI Breast Clinical Studies Group.

更新日期：2014-02-01 00:00:00

abstract：:The biochemical classification of the Klebsiella proposed by Cowan, Steel, Shaw, and Duguid (1960) has been applied to 50 strains isolated as the pure or predominant growth from sputum, and Klebsiella species have been correlated with the severity of the chest infection in the patient. A modification in nomenclature i...

journal_title：Journal of clinical pathology

authors： FOSTER WD,BRAGG J

更新日期：1962-09-01 00:00:00

abstract：AIMS:To investigate the expression of the placental cell-specific associated proteins in infantile haemangioma (IH). METHODS:Immunohistochemical staining was used to investigate the expression of human chorionic gonadotrophin (hCG), human placental lactogen (hPL), human leucocyte antigen-G (HLA-G), cytokeratin 7 (CK7)...

journal_title：Journal of clinical pathology

authors： Itinteang T,Tan ST,Guthrie S,Tan CE,McIntyre BC,Brasch HD,Day DJ

更新日期：2011-10-01 00:00:00

abstract：:A patient with chronic granulomatous disease who was being treated with steroids was diagnosed with a soft tissue Scedosporium apiospermum infection. Despite extensive treatment with antifungals progression to involve solid tissue (bone) occurred. Treatment required an HLA matched bone marrow transplant, which led to ...

journal_title：Journal of clinical pathology

authors： Gompels MM,Bethune CA,Jackson G,Spickett GP

更新日期：2002-10-01 00:00:00

abstract：AIMS:To investigate the association of cagA positivity and non-opsonic neutrophil activation capacity in wild-type Helicobacter pylori strains with peptic ulcer disease or chronic gastritis only. METHODS:Helicobacter pylori were isolated from antral biopsies of 53 consecutive patients with chronic antral gastritis, of...

journal_title：Journal of clinical pathology

authors： Danielsson D,Farmery SM,Blomberg B,Perry S,Rautelin H,Crabtree JE

更新日期：2000-04-01 00:00:00

abstract：:Sclerochoroidal calcification is an uncommon condition. Metabolic evaluation and clinical examination are important to exclude associated systemic conditions such as the Bartter and Gitelman syndromes. It has been suggested that the lesions seen in sclerochoroidal calcification are calcium pyrophosphate dihydrate crys...

journal_title：Journal of clinical pathology

authors： Gupta R,Hu V,Reynolds T,Harrison R

更新日期：2005-12-01 00:00:00

abstract：:A study has been made by clinical methods and by bio-assay of the effectiveness of a régime for prophylaxis against tetanus. The two principal objects of the method were to ensure that active immunization was offered to all patients who had received antitoxin and to measure the effect of the combined administration of...

journal_title：Journal of clinical pathology

authors： LAURENCE M,HOLT LB,GRAHAM CE,BONNEY GL

更新日期：1965-01-01 00:00:00

abstract：:Pathological findings are described in four cases of a new aminoaciduria in which homocystine is excreted in the urine. All the patients were mentally retarded children. Three of them presented diagnostic features of Marfan's syndrome. Necropsy on one case and biopsy findings in the others are described. Fatty change ...

journal_title：Journal of clinical pathology

authors： GIBSON JB,CARSON NA,NEILL DW

更新日期：1964-07-01 00:00:00

abstract：:An enzyme linked immunosorbent assay (ELISA) to measure free serum IgG antibodies to Pseudomonas aeruginosa in patients with cystic fibrosis was developed. Seven strains of P aeruginosa cells, treated with glutaraldehyde and representing the most commonly isolated serotypes in our cystic fibrosis unit, were used. The ...

journal_title：Journal of clinical pathology

authors： Brett MM,Ghoneim AT,Littlewood JM,Losowsky MS

更新日期：1986-10-01 00:00:00

abstract：:The excretion of 2,3-dinor-6-keto prostaglandin F1 alpha, a major urinary metabolite of prostacyclin, and the formation of thromboxane B2, a stable metabolite of thromboxane A2, by platelets stimulated by adenosine diphosphate, were studied in alcoholics, who had been admitted for detoxification. Once prolonged heavy ...

journal_title：Journal of clinical pathology

authors： Neiman J,Hillbom M,Benthin G,Anggård EE

更新日期：1987-05-01 00:00:00

abstract：AIMS:To evaluate the prevalence of pseudoangiomatous hyperplasia of mammary stroma in gynaecomastia and its immunohistochemical profile in this setting. METHODS:Eighty eight cases of gynaecomastia recovered from the files of the department of pathology, Botucatu School of Medicine from 1976 to 1996 were studied. In th...

journal_title：Journal of clinical pathology

authors： Milanezi MF,Saggioro FP,Zanati SG,Bazan R,Schmitt FC

更新日期：1998-03-01 00:00:00

abstract：AIMS:Next Generation Sequencing (NGS)-based BRCA tumour tissue testing poses several challenges. As a first step of its implementation within a regional health service network, an in-house validation study was compared with published recommendations. METHODS:Epithelial ovarian cancer (EOC) formalin-fixed paraffin-embe...

journal_title：Journal of clinical pathology

authors： Rivera D,Paudice M,Gismondi V,Anselmi G,Vellone VG,Varesco L,Ligurian BRCA Working Group.

更新日期：2020-09-07 00:00:00

abstract：AIMS:To audit the cellular expression of the innate antibacterial enzyme lysozyme in colonic biopsies from a cohort of patients having microscopic colitis (MC-collagenous colitis (CC) or lymphocytic colitis (LC)). Results were compared with those recorded in patients with inflammatory bowel disease (IBD) of the colon (...

journal_title：Journal of clinical pathology

authors： Rubio CA

更新日期：2011-06-01 00:00:00

abstract：AIMS:To isolate RNA and DNA simultaneously from formalin fixed paraffin wax embedded tissue to assess the clonality of enteropathy associated T cell lymphomas and to analyse it in detail by a non-radioactive method of T cell receptor complementarity determining region 3 (CDR3) spectratyping. METHODS:DNA and RNA were i...

journal_title：Journal of clinical pathology

authors： O'Shea U,Wyatt JI,Howdle PD

更新日期：1997-10-01 00:00:00

abstract：:A questionnaire was circulated to clinical biochemistry laboratories in the North West Thames region of the United Kingdom requesting information on extralaboratory equipment. Data on the types and numbers of instruments in use, their relationship with the laboratory, and quality assurance procedures were obtained. La...

journal_title：Journal of clinical pathology

authors： Burrin JM,Fyffe JA

更新日期：1988-09-01 00:00:00

abstract：:A 60 year old woman affected by Hashimoto's thyroiditis presented with a history of recurring episodes of urticaria and angio-oedema. Clinical and laboratory evaluation of the patient excluded allergy to external agents, hereditary angio-oedema, and occult infections. A pathogenic relation between Hashimoto's thyroidi...

journal_title：Journal of clinical pathology

authors： Amoroso A,Garzia P,Pasquarelli C,Sportelli G,Afeltra A

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:Hsulf-1 is a newly identified enzyme with arylsulphatase activity that can regulate the sulphation state of cell-surface heparan sulphate proteoglycans (HSPGs). In vitro overexpression of this enzyme in pancreatic cancer cells decreases responsiveness to fibroblastic growth factor-2, as Hsulf-1 is up regulat...

journal_title：Journal of clinical pathology

authors： Abiatari I,Kleeff J,Li J,Felix K,Büchler MW,Friess H

更新日期：2006-10-01 00:00:00

abstract：:The production of heparinase by a wide range of anaerobic bacteria isolated from clinical specimens was investigated. None of the 29 strains of Bacteroides fragilis produced heparinase. Of 62 other Bacteroides tested, only two of four strains of B ovatus, two of three strains of B thetaiotaomicron, and two of four str...

journal_title：Journal of clinical pathology

authors： Riley TV

更新日期：1987-04-01 00:00:00

abstract：AIMS:To determine the sensitivity of commercially available diagnostic assays for Chlamydia trachomatis using a simple method. METHODS:Nine commercial assays and an "in-house" polymerase chain reaction (PCR) were evaluated using serial dilutions of a laboratory grown H serovar--four of them using a laboratory grown E ...

journal_title：Journal of clinical pathology

authors： Thomas BJ,MacLeod EJ,Taylor-Robinson D

更新日期：1993-05-01 00:00:00

abstract：:Eighty-four children with acute lymphoblastic leukaemia (ALL) who had relapsed in bone marrow were studied to assess whether treatment would be more successful if relapse was detected before the disease became clinically evident. Patients whose relapse was detected by routine bone marrow examination before the disease...

journal_title：Journal of clinical pathology

authors： Haworth C,Heppleston AD,Morris Jones PH,Campbell RH,Evans DI,Palmer MK

更新日期：1981-05-01 00:00:00

abstract：:It has been suggested that Coxsackie B virus infections may play a part in causing or triggering myocardial infarction. This study was designed to compare the incidence of such infections in Coronary Care Unit patients and normal controls. The choice of a suitable criterion for diagnosis of Coxsackie infection is disc...

journal_title：Journal of clinical pathology

authors： O'Neill D,McArthur JD,Kennedy JA,Clements G

更新日期：1983-06-01 00:00:00