Oesophageal histology in long term users of non-steroidal anti-inflammatory drugs.

abstract：:A new rapid automated method for the identification and classification of microorganisms is described. It is based on the incorporation of 35S-methionine into cellular proteins and subsequent separation of the radiolabelled proteins by sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE). The protein ...

journal_title：Journal of clinical pathology

authors： Tabaqchali S,Silman R,Holland D

更新日期：1987-09-01 00:00:00

abstract：AIMS:To evaluate the efficacy of biochemical parameters in different fluids in the diagnosis of myocardial infarction of different causes, analysed after death. METHODS:The myoglobin concentration and total creatine kinase (CK) and creatine kinase MB isoenzyme (CK-MB) activities were measured in serum, pericardial flu...

journal_title：Journal of clinical pathology

authors： Perez-Cárceles MD,Osuna E,Vieira DN,Martínez A,Luna A

更新日期：1995-02-01 00:00:00

abstract：:A miniaturised method for the identification of anaerobic bacteria is described which employs microtitre fermentation tests, a spot indole test and a nitrate reduction disc test. The results obtained are directly comparable with those produced by a standard conventional method in use at present. ...

journal_title：Journal of clinical pathology

authors： Levett PN

更新日期：1984-01-01 00:00:00

abstract：AIMS:Diffuse large B-cell lymphoma (DLBCL) is an aggressive and potentially fatal disease. Prediction of risk of relapse is based on clinical markers. There is a need for more accurate biomarkers to select patients for more aggressive first-line treatments. Peroxiredoxins (Prxs) are a family of potent antioxidant prote...

journal_title：Journal of clinical pathology

authors： Kuusisto ME,Haapasaari KM,Turpeenniemi-Hujanen T,Jantunen E,Soini Y,Peroja P,Bloigu R,Karihtala P,Kuittinen O

更新日期：2015-07-01 00:00:00

abstract：:Improvements in the Zimmermann reaction are effected by using methanol as a solvent for the reagents employed in the reaction in place of ethanol or aqueous ethanol. The advantages are as follows. Considerably lower blanks are obtained; extraneous chromogens are negligible at the wavelength of measurement, so that no ...

journal_title：Journal of clinical pathology

authors： BEALE RN,BOSTROM JO,CROFT D

更新日期：1962-11-01 00:00:00

abstract：:Liver copper concentrations in percutaneous biopsy specimens were measured by neutron activation analysis and compared with histological staining for copper by rubeanic acid and rhodanine, and with copper-associated protein stained by orcein. Liver copper concentrations were elevated in 31 of 35 biopsies from patients...

journal_title：Journal of clinical pathology

authors： Jain S,Scheuer PJ,Archer B,Newman SP,Sherlock S

更新日期：1978-08-01 00:00:00

abstract：:Guidance by bacteriologists and changes in theatre and ward disciplines have greatly improved the results of urological surgery in recent years. The most noteworthy successes have been in treatment of chronic retention with renal failure, and in prevention of the bacteraemia which may occur following removal of the po...

journal_title：Journal of clinical pathology

authors： MITCHELL JP,GILLESPIE WA

更新日期：1964-09-01 00:00:00

abstract：:Five cases of malignant histiocytosis of the intestine and one case of true histiocytic lymphoma were studied using immunohistological techniques. In paraffin sections tumour cells in all cases were shown to contain alpha-1-antitrypsin and to express the leucocyte common antigen. Four of the five cases of malignant hi...

journal_title：Journal of clinical pathology

authors： Salter DM,Krajewski AS,Dewar AE

更新日期：1986-01-01 00:00:00

abstract：:Eighty-four children with acute lymphoblastic leukaemia (ALL) who had relapsed in bone marrow were studied to assess whether treatment would be more successful if relapse was detected before the disease became clinically evident. Patients whose relapse was detected by routine bone marrow examination before the disease...

journal_title：Journal of clinical pathology

authors： Haworth C,Heppleston AD,Morris Jones PH,Campbell RH,Evans DI,Palmer MK

更新日期：1981-05-01 00:00:00

abstract：:Several studies have recently documented the presence of persistently abnormal liver function tests in asymptomatic haemophiliacs. While the aetiology is unknown it is possible that repeated exposure to agents transmitted in blood products may be important. This study has attempted to determine the prevalence of viral...

journal_title：Journal of clinical pathology

authors： McVerry BA,Ross MG,Knowles WA,Voke J

更新日期：1979-04-01 00:00:00

abstract：:A case of abnormal chromatin clumping (ACC) which arose during the course of a myelodysplastic/myeloproliferative syndrome is described in a 61 year old woman who died of haemorrhage 43 months after diagnosis. Mature granulocytes exhibited the same nuclear abnormality described in other patients reported. Unusually, s...

journal_title：Journal of clinical pathology

authors： Gardais J

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:Triple-negative breast cancers (TNBCs) are defined by their lack of oestrogen receptor, progesterone receptor and epidermal growth factor receptor 2. Although heterogeneous, the majority are aggressive and treatment options are limited. Caveolin acts as tumour suppressor or promoter depending on the cancer t...

journal_title：Journal of clinical pathology

authors： Yeong J,Thike AA,Ikeda M,Lim JCT,Lee B,Nakamura S,Iqbal J,Tan PH

更新日期：2018-02-01 00:00:00

abstract：:Serum C reactive protein concentrations measured by a laboratory based assay were compared with the semiquantitative results obtained with a visual agglutination method (Well-cotest, CRP kit). Using this agglutination kit, diluting serum 1/10 and 1/20 gave C reactive protein results which could be of more clinical val...

journal_title：Journal of clinical pathology

authors： Richards NP,Elliott TS,Powell RJ,O'Callaghan C,Franklin P

更新日期：1985-04-01 00:00:00

abstract：AIMS:PCR amplicon-based next-generation sequencing (NGS) panels are increasingly used for clinical diagnostic assays. Amplification bias is a well-known limitation of PCR amplicon-based approaches. We sought to characterise lower-performance amplicons in an off-the-shelf NGS panel (TruSight Myeloid Sequencing Panel) fo...

journal_title：Journal of clinical pathology

authors： Yan B,Hu Y,Ng C,Ban KH,Tan TW,Huan PT,Lee PL,Chiu L,Seah E,Ng CH,Koay ES,Chng WJ

更新日期：2016-09-01 00:00:00

abstract：:One hundred and two bone marrow samples were analysed by histological and immunohistochemical methods for neurone specific enolase (NSE). The biopsies were performed to determine the extent of bone marrow disease in 84 neuroblastomas, nine embryonal rhabdomyosarcomas, five Ewing's sarcomas, two cases of Hodgkin's dise...

journal_title：Journal of clinical pathology

authors： Caillaud JM,Martinez-Madrigal F,Hartmann O,Carlu C

更新日期：1991-04-01 00:00:00

abstract：:Five hundred and seven strains of bacteria isolated from the urine of patients with significant bacteriuria (more than 10(8) colony-forming units per litre) were tested for sensitivity to co-trimoxazole by the agar diffusion technique. Each organism was tested with a combined disk containing trimethoprim and sulphamet...

journal_title：Journal of clinical pathology

authors： Amyes SG,Telfer Brunton WA

更新日期：1981-02-01 00:00:00

abstract：:Cyclospora cayetanensis is a cause of prolonged diarrhoea, mainly in travellers. Laboratory diagnosis may be achieved by a number of methods such as the staining of faecal smears by the modified Ziehl-Neelsen (ZN) technique. Safer methods using this technique have been described for the staining of acid fast bacilli a...

journal_title：Journal of clinical pathology

authors： Clarke SC,McIntyre M

更新日期：1996-06-01 00:00:00

abstract：:Colonising Campylobacter pyloridis were identified histologically in gastric biopsy specimens from 89% of 83 patients with non-ulcer dyspepsia and chronic gastritis, but not in 58 dyspeptic patients with normal mucosa. The presence and population density of organisms was associated with the presence of intraepithelial...

journal_title：Journal of clinical pathology

authors： Wyatt JI,Rathbone BJ,Heatley RV

更新日期：1986-08-01 00:00:00

abstract：AIMS:The aim of the present study was to immunohistochemically investigate the expression and prognostic significance of putative cancer stem cell markers CD117 (c-kit), CD34, CD20 and CD15 in a cohort of patients with primary choroidal and ciliary body melanoma. METHODS:The immunohistochemical expression of these mar...

journal_title：Journal of clinical pathology

authors： Lukenda A,Dotlic S,Vukojevic N,Saric B,Vranic S,Zarkovic K

更新日期：2016-03-01 00:00:00

abstract：AIMS:To show that medullary carcinomas of the thyroid are morphologically indistinguishable from gut carcinoids: the value of histochemistry in their identification and differential diagnosis from metastatic carcinoid tumours to the thyroid and some follicular cell neoplasms. METHODS:15 thyroid medullary carcinomas wi...

journal_title：Journal of clinical pathology

authors： Harach HR,Bergholm U

更新日期：1993-02-01 00:00:00

abstract：AIMS:Neoadjuvant chemoradiation therapy (CRT) is an increasingly used therapeutic strategy for rectal cancer. Clinically, it remains a major challenge to predict therapeutic response and patient outcome after CRT. Rsf-1 (HBXAP), a novel nuclear protein with histone chaperon function, mediates ATPase-dependent chromatin...

journal_title：Journal of clinical pathology

authors： Lin CY,Tian YF,Wu LC,Chen LT,Lin LC,Hsing CH,Lee SW,Sheu MJ,Lee HH,Wang YH,Shiue YL,Wu WR,Huang HY,Hsu HP,Li CF,Chen SH

更新日期：2012-08-01 00:00:00

abstract：:Muscle biopsy samples were analysed from five control subjects, four patients with mild to moderate fibre atrophy and four patients with severe atrophy. Patchy increase in lipid was noted with oil red O staining but there was no consistent association of lipid with selective fibre types. Ultrastructural studies demons...

journal_title：Journal of clinical pathology

authors： Sunnasy D,Cairns SR,Martin F,Slavin G,Peters TJ

更新日期：1983-07-01 00:00:00

abstract：:Infection with Vibrio vulnificus is uncommon in Europe but is associated with necrotising wound infections and life-threatening septicaemia. This case is one of infection most likely to have been acquired from a thermal pool in Turkey without preceding exposure to seawater or shellfish. The report also describes how e...

journal_title：Journal of clinical pathology

authors： Partridge DG,Townsend R,Larkin S,Parsons HK

更新日期：2009-04-01 00:00:00

abstract：AIMS:The aims of the study were to compare bacterial recovery following storage of sputum samples at 20 degrees C room temperature and 4 degrees C (refrigerated) for 24 h, and to determine the effect of postage on viable bacterial numbers. METHODS:A total of 38 individual sputum samples from clinically stable patients...

journal_title：Journal of clinical pathology

authors： Pye A,Hill SL,Bharadwa P,Stockley RA

更新日期：2008-03-01 00:00:00

abstract：:Components of the blood fibrinolytic system were measured in 43 patients with leukaemia. Increased fibrinolytic activity, indicated by a reduced plasma plasminogen level, was found in 14 patients. The combination of severe thrombocytopenia and increased fibrinolysis appeared to be a determinant in the production of a ...

journal_title：Journal of clinical pathology

authors： Ogston D,McAndrew GM,Ogston CM

更新日期：1968-03-01 00:00:00

abstract：:Pre-eclampsia complicated by deep jaundice occurred in a previously healthy primigravida. The main aetiological factor was disseminated intravascular coagulation; this caused both haemolysis and liver cell necrosis. Liver biopsy showed fibrin thrombi in the capillaries with microhaemorrhages and loss of periportal liv...

journal_title：Journal of clinical pathology

authors： Long RG,Scheuer PJ,Sherlock S

更新日期：1977-03-01 00:00:00

abstract：:In patients with chronic renal failure, blood samples for laboratory analysis are often taken via dialysis catheters. This report describes a case of gross spurious hypernatraemia in a blood sample collected from a patient undergoing haemodialysis. After centrifugation of the blood sample in question, the separator ge...

journal_title：Journal of clinical pathology

authors： Srivastava R,Murphy MJ,Card J,Severn A,Fraser CG

更新日期：2004-12-01 00:00:00

abstract：:The routine estimation of large numbers of serum folic acid and vitamin B(12) levels using the Baird and Tatlock(1) Analmatic clinical system is described and the method evaluated.Precision, accuracy, and carryover are shown to be at acceptable levels, and the advantages and disadvantages of the use of the system are ...

journal_title：Journal of clinical pathology

authors： Colvin G,Gibson GL,Neill DW

更新日期：1971-02-01 00:00:00

abstract：:Antibiotic discs from Oxoid, Mast, AB Biodisk, Difco, and Baltimore Biological Laboratories were compared, where discs of similar antibiotic content were available, in diffusion-sensitivity tests against organisms of known sensitivity. Discs from Oxoid and Mast gave zones 1-5 mm larger than discs from other manufactur...

journal_title：Journal of clinical pathology

authors： Brown DF,Kothari D

更新日期：1975-10-01 00:00:00

abstract：:A 45-year-old female patient underwent right hemihepatectomy for metastatic rectal adenocarcinoma. Preoperative imaging demonstrated an area of focal nodular hyperplasia (FNH) in segment VIII and metastatic carcinoma in segment VI of the liver. Gross and microscopic examination of the former lesion showed features typ...

journal_title：Journal of clinical pathology

authors： Nisar PJ,Zaitoun AM,Damera A,Hodi Z,Tierney GM,Beckingham IJ

更新日期：2002-12-01 00:00:00