Automation in clinical microbiology: a new approach to identifying micro-organisms by automated pattern matching of proteins labelled with 35S-methionine.

abstract：:The prevalence of Helicobacter pylori infection in patients with Barrett's oesophagus was studied prospectively. A sensitive immunohistochemical staining of H pylori was performed in oesophageal and gastric biopsies of 73 patients from a surveillance group with this condition. H pylori was detected in 11 cases of Barr...

journal_title：Journal of clinical pathology

authors： Ricaurte O,Fléjou JF,Vissuzaine C,Goldfain D,Rotenberg A,Cadiot G,Potet F

更新日期：1996-02-01 00:00:00

abstract：CLINICAL QUESTION:A 77-year-old man presented with haematuria. Cystoscopy revealed a papillary tumour in the trigone region of the bladder. A TURBT was performed. Review the high-quality, interactive digital Aperio slide at http://virtualacp.com/JCPCases/jclinpath-2016-204015 and consider your diagnosis. WHAT IS YOUR D...

journal_title：Journal of clinical pathology

authors： Trefor R,Varma M

更新日期：2017-07-01 00:00:00

abstract：AIMS:To determine the sensitivity and specificity of a multiplex PCR assay for the contemporary identification of major species involved in oral candidiasis, without extraction and purification of DNA from the samples under investigation; and evaluation of this method in comparison with routine phenotypic culture ident...

journal_title：Journal of clinical pathology

authors： Liguori G,Lucariello A,Colella G,De Luca A,Marinelli P

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:Many patients with advanced cancer are malnourished. Anorexia is common, as is the use of chemotherapy, which may cause nausea and poor appetite. Ten per cent of these patients experience haemorrhagic events. AIM:Since vitamin K deficiency (VKD) causes bleeding, to establish the prevalence of VKD in patient...

journal_title：Journal of clinical pathology

authors： Harrington DJ,Western H,Seton-Jones C,Rangarajan S,Beynon T,Shearer MJ

更新日期：2008-04-01 00:00:00

abstract：:Rocket-line immunoelectrophoresis (R-LIE) with antigen containing intermediate gel, and co-agglutination utilising protein A-containing staphylococci coated with specific antibodies, were adapted for serotyping the prototypes of group B meningococci. Both were found to have the same specificity as agar gel double diff...

journal_title：Journal of clinical pathology

authors： Danielsson D,Olcén P

更新日期：1979-02-01 00:00:00

abstract：INTRODUCTION:Modification of the spiral arteries with loss of the muscular vascular wall, invaded by the trophoblasts, represents the goal of the physiological vascular adaptation during human implantation. When physiological vascular changes do not occur, an unfavourable evolution of gestation may develop as suggested...

journal_title：Journal of clinical pathology

authors： Avagliano L,Bulfamante GP,Morabito A,Marconi AM

更新日期：2011-12-01 00:00:00

abstract：:Mesothelial lesions pose considerable diagnostic challenges not only because benign tumours, reactive proliferations and malignant mesothelioma can mimic one another, but also because the morphological patterns displayed by malignant mesothelioma can simulate a variety of epithelial and non-epithelial malignancies. Im...

journal_title：Journal of clinical pathology

authors： Butnor KJ

更新日期：2006-06-01 00:00:00

abstract：:Four hundred faecal samples, collected at approximately weekly intervals during the first year of life from nine babies, were examined for the presence of viruses. Only nine (2.3%) samples contained a virus detectable by electron microscopy, and on all but one occasion only one type of virus was present and that in sm...

journal_title：Journal of clinical pathology

authors： Harbour J,Shipp AP,Waller DK,Higgins PG

更新日期：1980-08-01 00:00:00

abstract：INTRODUCTION:Cellular blue naevi (CBN) measure 1-2 cm in diameter and affect the dermis, occasionally extending into the subcutaneous fat. The case of a 14-year-old boy with a giant CBN (GCBN) involving the right half of the face, the jugal mucosa and the lower eyelid with a tumour that had infiltrated the bone and the...

journal_title：Journal of clinical pathology

authors： Bittencourt AL,Monteiro DA,De Pretto OJ

更新日期：2007-01-01 00:00:00

abstract：:Eighty-four children with acute lymphoblastic leukaemia (ALL) who had relapsed in bone marrow were studied to assess whether treatment would be more successful if relapse was detected before the disease became clinically evident. Patients whose relapse was detected by routine bone marrow examination before the disease...

journal_title：Journal of clinical pathology

authors： Haworth C,Heppleston AD,Morris Jones PH,Campbell RH,Evans DI,Palmer MK

更新日期：1981-05-01 00:00:00

abstract：:The finding of raised growth hormone concentrations in patients with secondary malignancy in the liver is reported. These concentrations were significantly higher than those found in patients with primary malignancy only or in those with non-hepatic secondaries. A wide range of malignancies was investigated and the hi...

journal_title：Journal of clinical pathology

authors： Andrews GS

更新日期：1983-08-01 00:00:00

abstract：:In a post-mortem analysis of 1,500 patients, aged 70 years or more, heart disease and malignancy were the two major causes of death. Coronary disease was exceedingly prevalent, almost one in five being subject to this form of heart disease, and 13% dying from its effects. The levelling of the sex ratio in coronary dis...

journal_title：Journal of clinical pathology

authors： MCKEOWN F

更新日期：1963-11-01 00:00:00

abstract：:The cell volumes of mononuclear cells, T lymphocytes, B lymphocytes, and monocytes from the peripheral blood of 20 normal individuals were compared to neoplastic lymphoid cells from 14 patients with chronic lymphocytic leukaemia (CLL), 20 individuals with acute lymphocytic leukaemia (ALL), and 18 cases of non-Hodgkin'...

journal_title：Journal of clinical pathology

authors： Chapman EH,Kurec AS,Davey FR

更新日期：1981-10-01 00:00:00

abstract：:A method for the differential determination of plasma antithrombins, antithrombin III and alpha2 macroglobulin, is described. The method is based on the selective inactivation of plasma alpha2 macroglobulin by treatment with 0-1 M methylamine for 10 minutes at 37 degrees C and on the observation that antithrombin III ...

journal_title：Journal of clinical pathology

authors： Musumeci V,Vincenti A,Bizzi B

更新日期：1976-01-01 00:00:00

abstract：:A patient with chronic granulomatous disease who was being treated with steroids was diagnosed with a soft tissue Scedosporium apiospermum infection. Despite extensive treatment with antifungals progression to involve solid tissue (bone) occurred. Treatment required an HLA matched bone marrow transplant, which led to ...

journal_title：Journal of clinical pathology

authors： Gompels MM,Bethune CA,Jackson G,Spickett GP

更新日期：2002-10-01 00:00:00

abstract：:Late-stage ovarian carcinoma is almost universally fatal. BRCA mutations are associated with an improved outcome and enhanced sensitivity to platinum chemotherapy, yet recurrence and platinum resistance remain a major problem and highly effective regimens following platinum failure do not yet exist. Here we report a r...

journal_title：Journal of clinical pathology

authors： Osher DJ,Kushner YB,Arseneau J,Foulkes WD

更新日期：2011-10-01 00:00:00

abstract：AIMS:To evaluate aspects of the current practice of sentinel lymph node (SLN) pathology in breast cancer via a questionnaire based survey, to recognise major issues that the European guidelines for mammography screening should address in the next revision. METHODS:A questionnaire was circulated by mail or electronical...

journal_title：Journal of clinical pathology

authors： Cserni G,Amendoeira I,Apostolikas N,Bellocq JP,Bianchi S,Boecker W,Borisch B,Connolly CE,Decker T,Dervan P,Drijkoningen M,Ellis IO,Elston CW,Eusebi V,Faverly D,Heikkila P,Holland R,Kerner H,Kulka J,Jacquemier J,La

更新日期：2004-07-01 00:00:00

abstract：AIM:IgG4 disease is rare. However, IgG4 tubulointerstitial nephritis (TIN) is the most common renal manifestation. IgG4 disease is usually associated with elevated serum IgG4 levels and other organ involvement, low-density renal lesions on enhanced CT imaging and immune activation. The incidence of IgG4-TIN may be unde...

journal_title：Journal of clinical pathology

authors： Mac K,Wu XJ,Mai J,Howlin K,Suranyi M,Yong J,Makris A

更新日期：2017-06-01 00:00:00

abstract：:Human sperm heads were detected and tracked using semiautomatic image analysis. Measurements of size and shape on two specimens from each of 26 men showed that the major component of variability both within and between subjects was the number of small elongated sperm heads. Variability of the computed features between...

journal_title：Journal of clinical pathology

authors： Jagoe JR,Washbrook NP,Hudson EA

更新日期：1986-12-01 00:00:00

abstract：:A method is described for the estimation of serum free fatty acids based on the ultramicro method of Novák. The difficulty of obtaining an accurate standard graph has been overcome and the interfering effects of phospholipids have been reduced. The method is simple to perform and gives accurate, precise results in 50 ...

journal_title：Journal of clinical pathology

authors： Elphick MC

更新日期：1968-09-01 00:00:00

abstract：:Factor VIII procoagulant activity (VIII:C), factor VIII related antigen (VIIIR:AG), and the von Willebrand factor (VIII:WF) were measured in 19 patients with liver disease (8 cases of alcoholic cirrhosis and 11 with acute viral hepatitis). In both groups of patients the levels of VIII:C, VIIIR:AG, and VIIIR:WF were ab...

journal_title：Journal of clinical pathology

authors： Maisonneuve P,Sultan Y

更新日期：1977-03-01 00:00:00

abstract：:Serum C reactive protein concentrations measured by a laboratory based assay were compared with the semiquantitative results obtained with a visual agglutination method (Well-cotest, CRP kit). Using this agglutination kit, diluting serum 1/10 and 1/20 gave C reactive protein results which could be of more clinical val...

journal_title：Journal of clinical pathology

authors： Richards NP,Elliott TS,Powell RJ,O'Callaghan C,Franklin P

更新日期：1985-04-01 00:00:00

abstract：:The simultaneous estimation of steroids in plasma was carried out by the assay of cortisol, corticosterone, and testosterone. The method entails separation by means of thin layer chromatography, followed by conversion to a fluorophore and fluorimetric measurement. Its major advantages are its high specificity, its abi...

journal_title：Journal of clinical pathology

authors： Mattingly D,Martin H,Tyler C

更新日期：1989-06-01 00:00:00

abstract：AIMS:To investigate the relation between sarcoidosis and lymphoma. METHODS:The hospital notes of five patients with sarcoidosis and a lymphoproliferative disorder were reviewed. Histological material on which the diagnoses of sarcoidosis and lymphoma were made was re-analysed. RESULTS:Four of the five patients had we...

journal_title：Journal of clinical pathology

authors： Karakantza M,Matutes E,MacLennan K,O'Connor NT,Srivastava PC,Catovsky D

更新日期：1996-03-01 00:00:00

abstract：:This paper illustrates a simple method of necropsy dissection of the abdominal organs after abdominal surgery. The organs are removed in one block as per the method described by Letulle. A retroperitoneal approach is then used. Structures are dissected away in a series of layers using the vasculature for guidance. Thi...

journal_title：Journal of clinical pathology

authors： Culora GA,Roche WR

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND:Subgroups of breast cancer that have an impaired response to endocrine treatment, despite hormone receptor positivity, are still poorly defined. Breast cancer can be subdivided according to standard pathological parameters including histological type, grade, and assessment of proliferation. These parameters ...

journal_title：Journal of clinical pathology

authors： Jirström K,Rydén L,Anagnostaki L,Nordenskjöld B,Stål O,Thorstenson S,Chebil G,Jönsson PE,Fernö M,Landberg G

更新日期：2005-11-01 00:00:00

abstract：:Human astrovirus infection often causes outbreaks of self limiting diarrhoea, but may also infect patients who are immunodeficient or immunocompromised. Although there are previous publications relating to various aspects of astroviruses, there is a minimal amount of literature on the histopathological features of gas...

journal_title：Journal of clinical pathology

authors： Sebire NJ,Malone M,Shah N,Anderson G,Gaspar HB,Cubitt WD

更新日期：2004-09-01 00:00:00

abstract：:The pathological findings of an intradural and extramedullary cyst in the mid cervical spinal canal are described in a 55 year old woman who presented with a short history of pain and paraesthesia of the right arm. Intradural well defined solitary cystic lesions in the spinal canal are uncommon, their pathogenesis is ...

journal_title：Journal of clinical pathology

authors： Wilkinson N,Reid H,Hughes D

更新日期：1992-11-01 00:00:00

abstract：AIMS:To evaluate the effect of 10 day triple treatment on H pylori eradication and associated gastritis. METHODS:Fifty patients with H pylori positive non-ulcer dyspepsia were treated for 10 days with amoxicillin, tinidazole, and bismuth salts. Histological examination of the antral mucosa was performed before (T0), s...

journal_title：Journal of clinical pathology

authors： Di Napoli A,Petrino R,Boero M,Bellis D,Chiandussi L

更新日期：1992-09-01 00:00:00

abstract：:The pathological diagnoses and classification schemes for thyroid carcinoma have changed over the past 20 years and continue to do so. New entities have been described and molecular analyses have suggested better characterisation and grouping of certain tumours. Because some of the lesions have been named differently ...

journal_title：Journal of clinical pathology

authors： Baloch Z,LiVolsi VA,Tondon R

更新日期：2013-09-01 00:00:00