Excretion of faecal viruses during the first year of life.

abstract：BACKGROUND:An increased level of serum C-reactive protein (CRP) is a known prognostic factor for acute coronary events and sudden cardiac death, and it is associated with coronary calcification. CRP is expressed in coronary arteries, but its role in the development of coronary plaques is unclear. AIM:To investigate CR...

journal_title：Journal of clinical pathology

authors： Norja S,Nuutila L,Karhunen PJ,Goebeler S

更新日期：2007-05-01 00:00:00

abstract：:The simultaneous estimation of steroids in plasma was carried out by the assay of cortisol, corticosterone, and testosterone. The method entails separation by means of thin layer chromatography, followed by conversion to a fluorophore and fluorimetric measurement. Its major advantages are its high specificity, its abi...

journal_title：Journal of clinical pathology

authors： Mattingly D,Martin H,Tyler C

更新日期：1989-06-01 00:00:00

abstract：:The effects of several polyamines found in seminal fluid on the cell cycle and ploidy of three cervical cell lines and of primary epithelial cells cultured from cervical biopsy specimens were monitored by fluorescent flow cytometry. The rate of cell growth did not change but there were indications of either hypodiploi...

journal_title：Journal of clinical pathology

authors： Fletcher S,Neill WA,Norval M

更新日期：1991-05-01 00:00:00

abstract：AIMS:To detect cells bearing BRAF mutations in colorectal tumour samples and peritoneal washings, using a mismatch ligation assay (MLA). METHODS:DNA from 46 colorectal tumours was studied. Part of exon 15 of the BRAF gene was amplified using the polymerase chain reaction, and T-->A mutations at codon 600 were detected...

journal_title：Journal of clinical pathology

authors： Busby K,Morris A

更新日期：2005-04-01 00:00:00

abstract：AIMS:To evaluate and compare the long term prognostic value of the WHO classification and the computerised multivariate morphometrical D score in endometrial hyperplasia. To test the reproducibility of the D score in two different centres. METHODS:Histopathological WHO classification and computerised morphometrical an...

journal_title：Journal of clinical pathology

authors： Orbo A,Baak JP,Kleivan I,Lysne S,Prytz PS,Broeckaert MA,Slappendel A,Tichelaar HJ

更新日期：2000-09-01 00:00:00

abstract：AIMS:To evaluate the role of hepatocyte expression of leucocyte adhesion molecules and major histocompatibility complex (MHC) antigens in the pathogenesis of chronic viral hepatitis. METHODS:The expression of intercellular adhesion molecule 1 (ICAM-1), lymphocyte function associated antigen 3 (LFA-3), and MHC class I ...

journal_title：Journal of clinical pathology

authors： Chu CM,Liaw YF

更新日期：1993-11-01 00:00:00

abstract：:Cell surface proteolysis is an important mechanism for generating biologically active proteins that mediate a range of cellular functions and contribute to biological processes such as angiogenesis. Although most studies have focused on the plasminogen system and matrix metalloproteinases (MMPs), recently there has be...

journal_title：Journal of clinical pathology

authors： Noel A,Maillard C,Rocks N,Jost M,Chabottaux V,Sounni NE,Maquoi E,Cataldo D,Foidart JM

更新日期：2004-06-01 00:00:00

abstract：AIM:To evaluate the sources of fetal haemoglobin (HbF) as an indicator in cancer. An immunohistochemical study was carried out on some of the most common kinds of cancer. All of these cancers had serologically high levels of HbF as evaluated previously. METHODS:Immunoaffinity-purified anti-HbF was immunohistochemicall...

journal_title：Journal of clinical pathology

authors： Wolk M,Martin JE,Reinus C

更新日期：2006-06-01 00:00:00

abstract：:Components of the blood fibrinolytic system were measured in 43 patients with leukaemia. Increased fibrinolytic activity, indicated by a reduced plasma plasminogen level, was found in 14 patients. The combination of severe thrombocytopenia and increased fibrinolysis appeared to be a determinant in the production of a ...

journal_title：Journal of clinical pathology

authors： Ogston D,McAndrew GM,Ogston CM

更新日期：1968-03-01 00:00:00

abstract：:A case of squamous cell carcinoma of the terminal ileum with no underlying duplication or inflammatory disorder is described. The neoplasm seemed to have originated from the surface epithelium, invading the wall and metastasising to the regional lymph nodes. The 65 year old patient was free of disease three years afte...

journal_title：Journal of clinical pathology

authors： Platt CC,Haboubi NY,Schofield PF

更新日期：1991-03-01 00:00:00

abstract：:Rates of urinary excretion concomitant with the molecular size distribution of filtered polymer fragments were determined in five normovolaemic men dosed with 30 g/m2 BSA of a species of HES (HES 350/0.60) possessing a M-W of 350 000 combined with an MS of 0.60. Approximately 13% of the total injected dose of HES 350/...

journal_title：Journal of clinical pathology

authors： Mishler JM,Ricketts CR,Parkhouse EJ

更新日期：1981-04-01 00:00:00

abstract：AIM:The prognostic significance of perineural invasion (PNI) in oesophageal adenocarcinoma (EAC) is unclear. We examined the association of PNI with clinical outcomes in patients treated with neoadjuvant chemoradiotherapy (nCRT) and surgery. METHODS:We performed a single institutional retrospective study. We evaluated...

journal_title：Journal of clinical pathology

authors： Patel AK,Pan X,Vila DM,Frankel WL,Chen W,Perry KA,Merritt RE,D'Souza DM,Wuthrick EJ,Williams TM

更新日期：2020-04-21 00:00:00

abstract：BACKGROUND:Helicobacter pylori related gastric intestinal metaplasia (IM) is considered to be a precancerous lesion. AIMS:To identify the effects of H pylori eradication on K-ras mutations, cell kinetics in IM and histological changes in patients with and without gastric cancers in a one-year prospective study. METHO...

journal_title：Journal of clinical pathology

authors： Watari J,Tanaka A,Tanabe H,Sato R,Moriichi K,Zaky A,Okamoto K,Maemoto A,Fujiya M,Ashida T,Das KM,Kohgo Y

更新日期：2007-08-01 00:00:00

abstract：:The placenta is the fetal organ providing the interchange between mother and fetus. This organ needs to provide its function such as transport and secretion even during its development and thus all developmental changes need to be in accordance with its function. This review describes development of the placenta durin...

journal_title：Journal of clinical pathology

authors： Huppertz B

更新日期：2008-12-01 00:00:00

abstract：AIMS:To develop a quantitative reverse transcriptase polymerase chain reaction (Q-RT-PCR) for severe acute respiratory syndrome coronavirus (SARS-CoV) detection and explore the potential of using glyceraldehyde-3-phosphate dehydrogenase (GAPDH) mRNA as an internal control to exclude false negative results. METHODS:SAR...

journal_title：Journal of clinical pathology

authors： Wong SC,Chan JK,Lee KC,Lo ES,Tsang DN

更新日期：2005-03-01 00:00:00

abstract：AIM:To compare the attitudes of students towards the necropsy at different stages of their undergraduate career. METHOD:Students in the first, fourth and sixth academic years (n = 283) were asked to respond anonymously to a questionnaire comprised of 26 attitude statements. These statements dealt with the importance o...

journal_title：Journal of clinical pathology

authors： Botega NJ,Metze K,Marques E,Cruvinel A,Moraes ZV,Augusto L,Costa LA

更新日期：1997-01-01 00:00:00

abstract：:A 5 month old girl had typical clinical features of acute myocarditis just after the febrile period of exanthem subitum and died immediately. She had been healthy, with normal development, and there was no family history of particular note. Myocardial postmortem findings were compatible with acute myocarditis. Althoug...

journal_title：Journal of clinical pathology

authors： Yoshikawa T,Ihira M,Suzuki K,Suga S,Kito H,Iwasaki T,Kurata T,Tanaka T,Saito Y,Asano Y

更新日期：2001-10-01 00:00:00

abstract：:Autoinfective strongyloidiasis is often fatal in immunosuppressed patients or in immunocomprised hosts. An interesting case of Strongyloides stercolaris hyperinfection was seen in an immunocompetent patient. This report describes a case of fatal strogyloidiasis in a 79 year old man, who had suffered gastrointestinal d...

journal_title：Journal of clinical pathology

authors： Mayayo E,Gomez-Aracil V,Azua-Blanco J,Azua-Romeo J,Capilla J,Mayayo R

更新日期：2005-04-01 00:00:00

abstract：AIMS/BACKGROUND:A major medical role for postmortem examinations is the detection of clinically unexpected disease processes contributing to death. The aim of the present study was to determine whether simple clinical parameters can predict the presence of important unanticipated findings at necropsy. METHODS:Prospect...

journal_title：Journal of clinical pathology

authors： Robinson IA,Marley NJ

更新日期：1996-11-01 00:00:00

abstract：:Gastrointestinal cell proliferation plays an important role in the maintenance of the integrity of the gastrointestinal system. The study of gastrointestinal proliferation kinetics allows a better understanding of the complexity of the system, and also has important implications for the study of gastrointestinal carci...

journal_title：Journal of clinical pathology

authors： Wong WM,Wright NA

更新日期：1999-05-01 00:00:00

abstract：AIMS:To characterise further the proliferative compartment of the normal cervix and to document its alteration, if any, in the various grades of cervical intraepithelial neoplasia (CIN), particularly changes to the basal epithelial layer; to hypothesise as to the diagnostic and biological significance of any observed d...

journal_title：Journal of clinical pathology

authors： Payne S,Kernohan NM,Walker F

更新日期：1996-08-01 00:00:00

abstract：:Of 30 children with bleeding disorders exposed to an index tuberculosis case, six developed primary pulmonary tuberculosis and two others became positive skin reactors. There was a significant correlation between the amount of replacement treatment received and the development of evidence of tuberculous infection. Onl...

journal_title：Journal of clinical pathology

authors： Beddall AC,Hill FG,George RH,Williams MD,Al-Rubei K

更新日期：1985-10-01 00:00:00

abstract：:The distribution and quantitative expression of HBcAg in relation to serum HBeAg and liver histology before and after a trial of interferon in 50 patients with chronic type B hepatitis were evaluated using polyclonal and monoclonal antibodies. In general, both antisera showed a similar pattern in terms of the distribu...

journal_title：Journal of clinical pathology

authors： Chu CM,Lin SM,Liaw YF

更新日期：1991-01-01 00:00:00

abstract：AIMS:Our laboratory is a centralised centre receiving routine non-small cell lung cancer (NSCLC) samples for programmed death ligand-1 (PD-L1) immunohistochemical (IHC) evaluation. Since literature data are not concordant here we review our clinical records to assess the rate of PD-L1 positive and negative NSCLC cases ...

journal_title：Journal of clinical pathology

authors： Vigliar E,Malapelle U,Iaccarino A,Acanfora G,Pisapia P,Clery E,De Luca C,Bellevicine C,Troncone G

更新日期：2019-06-01 00:00:00

abstract：AIMS:Strong thyroglobulin immunoreactivity within sinus histiocytes in a lymph node draining a papillary thyroid carcinoma was observed in a recent case. This prompted the investigation of whether thyroglobulin immunoreactivity is common in regional lymph nodes in cases of thyroid malignancy. METHODS:Eighty seven lymp...

journal_title：Journal of clinical pathology

authors： Venkatraman L,Maxwell P,McCluggage WG

更新日期：2001-04-01 00:00:00

abstract：AIMS:In the gastric antrum and body, foveolar hyperplasia is a feature of reactive gastritis resulting from--for example, duodenogastric bile reflux and the use of non-steroidal anti-inflammatory drugs (NSAIDs). The aim of this study was to examine the occurrence and clinical relevance of gastric cardiac foveolar hyper...

journal_title：Journal of clinical pathology

authors： Voutilainen M,Juhola M,Färkkilä M,Sipponen P

更新日期：2002-05-01 00:00:00

abstract：:In a post-mortem analysis of 1,500 patients, aged 70 years or more, heart disease and malignancy were the two major causes of death. Coronary disease was exceedingly prevalent, almost one in five being subject to this form of heart disease, and 13% dying from its effects. The levelling of the sex ratio in coronary dis...

journal_title：Journal of clinical pathology

authors： MCKEOWN F

更新日期：1963-11-01 00:00:00

abstract：:In vitro morphological and functional studies were carried out on platelets which had been cryopreserved in the presence of 5% dimethyl sulphoxide (DMSO). Overall loss of platelets was around 50%. Those which survived freezing and reconstitution showed marked morphological deterioration, increase of procoagulant activ...

journal_title：Journal of clinical pathology

authors： Baythoon H,Tuddenham EG,Hutton RA

更新日期：1982-08-01 00:00:00

abstract：AIMS:Heightened B-cell receptor (BCR) activity in diffuse large B-cell lymphoma (DLBCL) is well established, and a subset of patients with relapsed DLBCL can benefit from BCR-targeted therapies. Universal outreach of such emerging therapies mandates forming a global landscape of BCR molecular signalling in DLBCL, inclu...

journal_title：Journal of clinical pathology

authors： Masir N,Akhter A,Roshan TM,Florence CS,Abdul-Rahman F,Tumian NR,Kean-Chang P,Elyamany G,Shabani-Rad MT,Mansoor A

更新日期：2019-09-01 00:00:00

abstract：AIMS:This is a qualitative study of the perceived learning needs of trainees for graded responsibility in histopathological training in the UK. METHODS:A focus group with trainees and interviews with consultants was carried out. Participants were asked 'What do you perceive are the learning needs of histopathology tra...

journal_title：Journal of clinical pathology

authors： Finall A,Allery L

更新日期：2016-01-01 00:00:00