Does the width of the surgical margin of safety or premalignant dermatoses at the negative surgical margin affect outcome in surgically treated penile cancer?

abstract：AIMS:In the gastric antrum and body, foveolar hyperplasia is a feature of reactive gastritis resulting from--for example, duodenogastric bile reflux and the use of non-steroidal anti-inflammatory drugs (NSAIDs). The aim of this study was to examine the occurrence and clinical relevance of gastric cardiac foveolar hyper...

journal_title：Journal of clinical pathology

authors： Voutilainen M,Juhola M,Färkkilä M,Sipponen P

更新日期：2002-05-01 00:00:00

abstract：:A simple, standardised procedure was used for processing data from External Quality Assessment Schemes and for producing performance charts. A graphic presentation of cumulative performance is generated for each test, using an integrated software package to display results in a standardised format. This permits interp...

journal_title：Journal of clinical pathology

authors： Ardern JC,Hyde K,Hickman L,Urmston A,Burgess R,Burn AM,Geary CG

更新日期：1991-01-01 00:00:00

abstract：AIMS:Common variable immunodeficiency (CVID) is the most common serious primary immunodeficiency. This paper describes the immunological consequences of human immunodeficiency virus (HIV) infection in a patient with familial CVID subsequently treated with highly active antiretroviral therapy (HAART). METHODS:Serial me...

journal_title：Journal of clinical pathology

authors： Jolles S,Tyrer M,Johnson M,Webster D

更新日期：2001-09-01 00:00:00

abstract：AIM:To examine peripheral blood and skeletal muscle from patients with chronic fatigue syndrome for exogenous retrovirus. METHODS:Blood samples from 30 patients and muscle biopsy specimens of 15 patients were examined for retroviral sequences by DNA extraction, polymerase chain reaction (PCR), and Southern blotting hy...

journal_title：Journal of clinical pathology

authors： Gow JW,Simpson K,Schliephake A,Behan WM,Morrison LJ,Cavanagh H,Rethwilm A,Behan PO

更新日期：1992-12-01 00:00:00

abstract：AIMS:(1) To investigate the immunohistochemical expression of the multidrug resistance gene (MDR1) product P-glycoprotein in histological samples from 31 hepatocellular carcinomas (HCCs); and (2) to correlate the results with cell proliferation, p53 expression, the disease-free interval, and cumulative patient survival...

journal_title：Journal of clinical pathology

authors： Soini Y,Virkajärvi N,Raunio H,Pääkkö P

更新日期：1996-06-01 00:00:00

abstract：OBJECTIVE:To compare the whole genomes sequencing (WGS) results in the 100K Genomes project with the results of routine molecular diagnostics in precision medicine. MATERIALS AND METHODS:We analysed 374 cancers including a high tumour mutational burden (TMB-high) subgroup, defined as >10 non-synonymous single nucleoti...

journal_title：Journal of clinical pathology

authors： Echejoh G,Liu Y,Chung-Faye G,Charlton J,Moorhead J,Clark B,Davidson P,Sarker D,Ross P,Ooft ML

更新日期：2020-10-29 00:00:00

abstract：:Serine esterases were detected in the granules of mucosal mast cells from rat, mouse, sheep, and man. Successful demonstration of enzyme activity required brief fixation (6 h) of tissues in 4% paraformaldehyde. Staining with naphthol AS-D chloroacetate produced an intense red reaction product in intraepithelial mucosa...

journal_title：Journal of clinical pathology

authors： Huntley JF,Newlands GF,Gibson S,Ferguson A,Miller HR

更新日期：1985-04-01 00:00:00

abstract：:Expression profiling has been extensively applied to the study of breast cancer and undoubtedly is changing the way breast cancer is perceived. Over the past few years, several groups have described prognostic "signatures" (gene lists) that are purported to be more accurate prognostic factors than well established cli...

journal_title：Journal of clinical pathology

authors： Reis-Filho JS,Westbury C,Pierga JY

更新日期：2006-03-01 00:00:00

abstract：AIMS:To investigate the expression of catenins (alpha, beta, and gamma) in non-small cell lung carcinoma (NSCLC) and its relation to clinicopathological factors and prognosis. METHODS:The expression of catenins was analysed immunohistochemically in 261 patients with resected NSCLC, diagnosed between 1978 and 1996 in e...

journal_title：Journal of clinical pathology

authors： Pirinen RT,Hirvikoski P,Johansson RT,Hollmén S,Kosma VM

更新日期：2001-05-01 00:00:00

abstract：:The sensitivity of 12 commonly used anti-HIV-1/HIV-2 enzyme immunoassays was evaluated. The assays, each of which utilises at least one synthetic HIV antigen, were tested against a panel of 1092 specimens previously designated anti-HIV positive. In a total of 13 104 tests there were eight false negative results attrib...

journal_title：Journal of clinical pathology

authors： McAlpine L,Parry JV,Shanson D,Mortimer PP

更新日期：1995-05-01 00:00:00

abstract：AIMS:Positive direct antiglobulin tests (DATs) are valuable in identifying the aetiology of autoimmune haemolysis and in guiding therapeutic intervention. However, in HIV-positive individuals with background polyclonal gammopathy, a positive DAT in the absence of haemolysis is common. In this setting, IgG quantificatio...

journal_title：Journal of clinical pathology

authors： Chetty T,Bouwer N,Wan YO,Mahlangu J

更新日期：2020-12-16 00:00:00

abstract：:Monoclonal antibodies to factor VIII antigen (VIII:Ag) and von Willebrand factor (vWf:Ag) were immobilised on Sephacryl S-1000 and tested for their ability to deplete normal human citrated plasma of factor VIII. A combination of two antibodies to VIII:Ag and one antibody to vWf:Ag was required to produce plasma contai...

journal_title：Journal of clinical pathology

authors： Hornsey VS,Waterston YG,Prowse CV

更新日期：1988-05-01 00:00:00

abstract：AIMS:To establish the number of histological levels necessary for the evaluation of breast needle core biopsy (NCB) specimens taken from areas of mammographic calcification in patients presenting via the UK National Health Service Breast Screening Programme. METHODS:Retrospective review of a series of breast NCB speci...

journal_title：Journal of clinical pathology

authors： Kumaraswamy V,Carder PJ

更新日期：2007-06-01 00:00:00

abstract：AIMS:To assess the effect of cellulosic dialysis membranes on the production of complement degradation products to determine to the role of the classical pathway. METHOD:Complement activation was studied in 33 patients during a single haemodialysis session using cellulosic membranes. Pre- and post-dialysis plasma EDTA...

journal_title：Journal of clinical pathology

authors： Innes A,Farrell AM,Burden RP,Morgan AG,Powell RJ

更新日期：1994-02-01 00:00:00

abstract：AIMS:An increase in the proliferative state of the gastric epithelium has been attributed to infection with Helicobacter pylori. In order to obtain a more precise estimate of the magnitude of this change, the proliferative state of 17 cases of florid H pylori associated follicular gastritis was examined using the antib...

journal_title：Journal of clinical pathology

authors： Havard TJ,Sarsfield P,Wotherspoon AC,Steer HW

更新日期：1996-01-01 00:00:00

abstract：AIMS:To investigate the morphological and histopathological associations between an individual pit seen on stereomicroscopy or magnifying colonoscopy and an individual crypt seen in histological sections; and to examine these associations in colorectal tumours. METHODS:Fourteen thousand and twenty three cases were exa...

journal_title：Journal of clinical pathology

authors： Kudo S,Hirota S,Nakajima T,Hosobe S,Kusaka H,Kobayashi T,Himori M,Yagyuu A

更新日期：1994-10-01 00:00:00

abstract：:A woman with peripheral vascular disease developed cytomegalovirus colitis following repair of abdominal aortic aneurysm. Cytomegalovirus colitis developing in an immunocompetent individual may be caused by a breach in the integrity of the mucosal lining of the colon from various causes and should alert the clinician ...

journal_title：Journal of clinical pathology

authors： al Mahdy H

更新日期：1998-06-01 00:00:00

abstract：:Circulating immune complexes have been detected in the sera of 24 Nigerian children with acute poststreptococcal glomerulonephritis using two methods. There was a significant correlation between levels of soluble complexes, detected in samples taken from patients in the oliguric phase of acute nephritis, and severity ...

journal_title：Journal of clinical pathology

authors： Onyewotu II,Mee J

更新日期：1978-09-01 00:00:00

abstract：AIMS:To study the overexpression of p53 protein in Barrett's oesophagus with adenocarcinoma, and to correlate this expression with the pathological features of Barrett's syndrome. METHODS:Immunohistochemical staining was performed on frozen sections with a monoclonal antibody directed against wild type and mutated p53...

journal_title：Journal of clinical pathology

authors： Fléjou JF,Potet F,Muzeau F,Le Pelletier F,Fékété F,Hénin D

更新日期：1993-04-01 00:00:00

abstract：:The prevalence of lymphoid follicles in endoscopic biopsy specimens from normal antral mucosa (n = 220), mucosa with reflux gastritis (n = 104), and in cases with Campylobacter pylori-associated gastritis (n = 2544) was studied. In the latter group whether there were associations between degree and activity of gastrit...

journal_title：Journal of clinical pathology

authors： Stolte M,Eidt S

更新日期：1989-12-01 00:00:00

abstract：AIMS:To use the polymerase chain reaction to detect monoclonality at the immunoglobulin heavy chain gene locus in cells derived from lymph node aspirates. METHODS:A nested two-stage polymerase chain reaction (PCR) for the VDJ region of the immunoglobulin heavy chain gene was used to detect monoclonality. The total num...

journal_title：Journal of clinical pathology

authors： Wan JH,Sykes PJ,Orell SR,Morley AA

更新日期：1992-05-01 00:00:00

abstract：:The laboratory findings in seven cases of endocarditis caused by coagulase-negative staphylococci are presented. The usefulness of biochemical characterization of the strains in diagnosis and the selection of antibiotics for prophylaxis and treatment are discussed. ...

journal_title：Journal of clinical pathology

authors： Speller DC,Mitchell RG

更新日期：1973-07-01 00:00:00

abstract：:Adenocarcinoma of the anal glands is very rare but it is an important lesion to recognise as with early diagnosis, it has an excellent prognosis. Because it involves the submucosa widely and penetrates the mucosa late, it can be mistaken for metastatic gastrointestinal carcinoma, or tumour arising in sinuses and fistu...

journal_title：Journal of clinical pathology

authors： Behan WM,Burnett RA

更新日期：1996-12-01 00:00:00

abstract：AIMS:Immunohistochemical stains have greatly improved the diagnostic accuracy of renal cell carcinoma (RCC) for primary and distant tumours. We evaluate a marker that has recently been incorporated in clinical practice, PAX-8, in primary and metastatic RCCs. METHODS:Two distinct tissue microarrays were used, one consi...

journal_title：Journal of clinical pathology

authors： Barr ML,Jilaveanu LB,Camp RL,Adeniran AJ,Kluger HM,Shuch B

更新日期：2015-01-01 00:00:00

abstract：:A severe non-dose related skin eruption attributable to treatment with captopril was recently reported: this is distinct from the dose related rashes that have been widely described. Ultrastructural and immunohistochemical studies were carried out to determine in detail the histological features of this eruption: the ...

journal_title：Journal of clinical pathology

authors： Furness PN,Goodfield MJ,MacLennan KA,Stevens A,Millard LG

更新日期：1986-08-01 00:00:00

abstract：:Gastrointestinal (GI) symptoms including abdominal pain, bloating and diarrhoea are a relatively common reason for consulting a physician. They may be due to inflammatory bowel disease (inflammatory bowel disease; Crohn's disease, ulcerative colitis and indeterminate colitis), malignancy (colorectal cancer), infectiou...

journal_title：Journal of clinical pathology

authors： Sherwood RA

更新日期：2012-11-01 00:00:00

abstract：AIMS:To develop a specific radioimmunoassay for the routine determination of serum vitamin B12. METHODS:Antisera were raised in rabbits by immunisation with the monocarboxylic acid derivative of cyanocobalamin coupled to human serum albumin. Antibody titres and affinities were determined and the antiserum giving the h...

journal_title：Journal of clinical pathology

authors： O'Sullivan JJ,Leeming RJ,Lynch SS,Pollock A

更新日期：1992-04-01 00:00:00

abstract：:Tubulocystic carcinoma (TCC) is a very rare renal tumour with unique gross and microscopic features, alternatively considered as low-grade collecting duct carcinoma. Recent studies favoured distinction of TCC from collecting duct carcinoma, and some cases of TCC synchronously coexisting with other renal cell tumour su...

journal_title：Journal of clinical pathology

authors： Chen N,Nie L,Gong J,Chen X,Xu M,Chen M,Zhou Q

更新日期：2014-11-01 00:00:00

abstract：:Aztreonam blood agar, a new selective medium for Gram positive aerobic bacteria, was evaluated in comparison with conventional media for skin swabs. Aztreonam agar increased the number of isolates of Staphylococcus aureus by 17%. By producing purer growths on primary isolation, it significantly speeded up the identifi...

journal_title：Journal of clinical pathology

authors： Wood W,Harvey G,Olson ES,Reid TM

更新日期：1993-08-01 00:00:00

abstract：:Cryostat sections from 160 rectal suction biopsies were stained for cholinesterases by the method of Karnovsky and Roots (1964) in an attempt to facilitate the diagnosis of Hirschsprung's disease. The method proved at least as reliable as experienced assessment of paraffin haematoxylin-eosin sections, and appeared to ...

journal_title：Journal of clinical pathology

authors： Trigg PH,Belin R,Haberkorn S,Long WJ,Nixon HH,Plaschkes J,Spitz L,Willital GH

更新日期：1974-03-01 00:00:00