Abstract:
AIMS:The aim of this study was to assess the prevalence and drug resistance of Ureaplasma species and Mycoplasma hominis in outpatients with genital manifestation from 2005 to 2013 in Hangzhou, China. METHODS:A total of 2689 female and 2336 male patients with various genital symptoms were included in this study. Species identification and antimicrobial susceptibility test were performed by using the mycoplasma IST-2 kit. RESULTS:The prevalence rate of Ureaplasma species was 39.9%, M hominis was 1.2% in female patients, and the coinfection rate was 13.4%; while in males, the prevalence rate of Ureaplasma species was 18.8%, M hominis was 0.4%, and the coinfection rate was 2.9%. Moreover, significantly high positive rates for mycoplasmas (Ureaplasma species M hominis) and were found in 16–20-year-old females (65.2%) and males (27.3%). Ureaplasma species and M hominis displayed relatively lower resistance rates (<5.0%) to doxycycline, josamycin, tetracycline and pristinamycin, and the resistance rates did not change during the study period, while the resistance rates of Ureaplasma species to quinolones (ofloxacin and ciprofloxacin) were much higher (>50%) and increased significantly from 2005 to 2013. CONCLUSIONS:Our study indicates that high positive rates of Ureaplasma species and M hominis were found in young outpatients with genital symptoms, and monitoring the local drug resistance is critical for prevention of the occurrence of resistant strains.
journal_name
J Clin Patholjournal_title
Journal of clinical pathologyauthors
Song T,Ye A,Xie X,Huang J,Ruan Z,Kong Y,Song J,Wang Y,Chen J,Zhang Jdoi
10.1136/jclinpath-2014-202248subject
Has Abstractpub_date
2014-09-01 00:00:00pages
817-20issue
9eissn
0021-9746issn
1472-4146pii
jclinpath-2014-202248journal_volume
67pub_type
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doi:10.1136/jcp.36.3.353
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journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.28.9.728
更新日期:1975-09-01 00:00:00
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journal_title:Journal of clinical pathology
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journal_title:Journal of clinical pathology
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journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.46.5.408
更新日期:1993-05-01 00:00:00
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journal_title:Journal of clinical pathology
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