Abstract:
OBJECTIVE:To compare the performance of respiratory rate and other clinical signs against pulse oximetry for predicting hypoxia in children with Severe pneumonia/Very severe disease as per Integrated Management of Neonatal and Childhood Illness (IMNCI) classification. DESIGN:Cross-sectional study. SETTING:Pediatric emergency department of a tertiary-care hospital in Delhi, India. SUBJECTS:112 hospitalized children (2 mo - 5 y) with Severe pneumonia/Very severe disease as per IMNCI classification. METHODS:Respiratory rate was recorded at enrolment, along with other clinical signs and symptoms. Oxygen saturation (SpO2) was measured by a pulse oximeter. Clinical predictors of hypoxia (SpO2 <90%) and their combinations (index test) were evaluated for their sensitivity, specificity, positive predictive value and negative predictive value for diagnosis of hypoxia, against pulse oximetry (reference test). RESULTS:Hypoxia was present in 57 (50.9%) children. Presence of tachypnea, head nodding, irritability, inability to drink/breastfeed, vomiting, and altered sensorium was significantly associated with hypoxia (P<0.05). Multiple logistic regression revealed that age-specific tachypnea (RR≥70/min for 2-12 mo, and RR ≥60/min for ≥12 mo), head nodding, and inability to drink/breastfeed were independent predictors for hypoxia with sensitivity of 70.2%, 50.9% and 75.4%, respectively; and specificity of 88.9%, 96.4%, and 90.9%, respectively. When all three predictors were used in conjunction, the sensitivity increased to 91.2% and specificity was 81.8%. CONCLUSION:No single clinical sign can perform as well as pulse oximetry for predicting hypoxia in children with severe pneumonia. In settings where pulse oximetry is not available, combination of signs, age-specific tachypnea, head nodding, and inability to drink/breastfeeding has acceptable sensitivity and specificity.
journal_name
Indian Pediatrjournal_title
Indian pediatricsauthors
Alwadhi V,Dewan P,Malhotra RK,Shah D,Gupta Pdoi
10.1007/s13312-017-1163-6subject
Has Abstractpub_date
2017-09-15 00:00:00pages
729-734issue
9eissn
0019-6061issn
0974-7559pii
S097475591600063journal_volume
54pub_type
杂志文章abstract:OBJECTIVE:To analyze variation in rotavirus-positivity using simple alternative statistical measures. METHODS:Hospital-based rotavirus surveillance among children admitted with acute gastroenteritis between 2005 and 2009. Prevalence, adjusted proportions and symmetrized index were calculated. RESULTS:Rotavirus preval...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-016-0898-9
更新日期:2016-07-08 00:00:00
abstract:OBJECTIVE:To evaluate the profile of children with central diabetes insipidus (DI) and identify factors indicating organic etiology. DESIGN:Retrospective chart review. SETTING:Tertiary referral hospital. SUBJECTS:Fifty-nine children with central DI (40 boys, 19 girls). METHODS:Features of organic and idiopathic cen...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2008-06-01 00:00:00
abstract::Familial chylomicronemia syndrome is a group of rare genetic disorders characterized by deficient activity of an enzyme lipoprotein lipase or apo-protein C-II deficiency. In this paper we present an infant with massive hyperchylomicronemia and severe pancreatitis. Exchange transfusion for controlling hypertriglyceride...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2007-04-01 00:00:00
abstract:BACKGROUND:Improved survival seen in Acute Lymphoblastic Leukemia (ALL) cases has led to increased reports of second malignant neoplasms. CASE CHARACTERISTICS:A 12-year-old female treated for ALL using UK ALL XI protocol nine years back presented with progressively increasing pre-auricular swelling. OBSERVATION:Inves...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-015-0757-0
更新日期:2015-11-01 00:00:00
abstract::Lead levels were measured by atomic absorption spectrophotometry in umbilical cord blood samples of 205 consecutively born neonates and venous blood in 62 of the mothers. The mean (+/- SD) cord blood lead level was 4.7 +/- 12.1 microg/dL. In the sub sample of 62 mother-baby pairs, the mean (+/- SD) cord blood lead lev...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2009-09-01 00:00:00
abstract:JUSTIFICATION:There is a need to revise/review recommendations regarding existing vaccines in view of current developments in vaccinology. PROCESS:Advisory Committee on Vaccines and Immunization Practices (ACVIP) of Indian Academy of Pediatrics (IAP) reviewed the new evidence, had two meetings, and representatives of ...
journal_title:Indian pediatrics
pub_type: 杂志文章,实务指引
doi:
更新日期:2018-12-15 00:00:00
abstract:OBJECTIVE:To evaluate serum leptin levels in obese Indian children and its correlation to anthropometric and biochemical parameters. DESIGN:Cohort study. SETTING:Referral tertiary hospital. METHODOLOGY:Leptin levels were measured in 36 children (26 boys, age 1.5 to 15 years) and 37 adults (21 men, age 25 to 69 years...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2007-04-01 00:00:00
abstract:OBJECTIVE:To study the clinical profile of children with scrub typhus and its association with hemophagocytic lymphohistiocytosis. METHODS:Children presenting with unexplained fever and multi-systemic involvement between May to December 2011 were tested for scrub typhus using IgM ELISA kits. Occurrence of Hemophagocyt...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-014-0470-4
更新日期:2014-08-01 00:00:00
abstract:BACKGROUND:Posterior reversible encephalopathy syndrome (PRES) is a benign disorder of reversible subcortical vasogenic cerebral edema. CASE CHARACTERISTICS:A 13-yr-old girl presented 4 days after complete recovery from diabetic ketoacidosis with symptoms of headache, altered sensorium, seizures, and visual loss. Ther...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2019-03-15 00:00:00
abstract:OBJECTIVE:To evaluate simple clinical signs of illness in young infants (0 to 2 months) and to correlate with WHO IMCI algorithm (7 days-2 months). DESIGN:Prospective observational. Study conducted in the outpatient department and emergency room of a pediatric tertiary level hospital. METHODS:Four hundred and ninety ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2006-12-01 00:00:00
abstract::International Union of Immunological Societies working group recently updated the human inborn errors of immunity. This classification includes 65 new disorders that have been added since the last classification in 2018. This article highlights the important aspects of new classification for the benefit of general ped...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2020-06-15 00:00:00
abstract::India established the National Tuberculosis Control Project (NTCP) 50 years ago and re-designed it as Revised NTCP (RNTCP) 19 years ago. Tuberculosis (TB) control was beset with obstacles-BCG vaccination was found ineffective in TB control in 1979; human immunodeficiency virus began spreading in India since 1984 with ...
journal_title:Indian pediatrics
pub_type: 历史文章,杂志文章
doi:10.1007/s13312-013-0021-4
更新日期:2013-01-08 00:00:00
abstract:OBJECTIVE:To estimate the prevalence of non-exclusive breastfeeding (NEBF) and quantify the out-of-pocket expenditure (OOPE) associated with NEBF and treatment of morbidity among infants up to six months of age. METHODS:Community based in an urban slum, among 172 mother-infant dyads selected by systematic random sampl...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2020-12-15 00:00:00
abstract:OBJECTIVE:To determine whether interactional group discussions could reduce prescriptions of injections by physicians. STUDY DESIGN:Randomized controlled trial. SETTING:Rural public health care facilities, North 24 Parganas district, West Bengal, India. SUBJECTS:72 medical officers, 36 each in intervention and contr...
journal_title:Indian pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1007/s13312-010-0076-4
更新日期:2010-05-01 00:00:00
abstract:OBJECTIVE:To provide tribe- specific child mortality rates and health indicators from selected states in India. METHODS:We used Census 2011 data and Coale Demney methodology to estimate the infant mortality rate (IMR), under-five mortality rate (U5MR) and expectation of life at birth (LEB) for 123 tribes of selected s...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2021-01-15 00:00:00
abstract::This report is based on observations during the conduct of a study of hypocalcemia in infants and children. In a study of 50 cases, 13 exclusively breast fed infants manifesting with hypocalcemic seizures were confirmed to have vitamin D deficiency. None of the 13 infants had received vitamin D supplementation. All of...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2006-03-01 00:00:00
abstract::Two hundred and fifty eight newborn babies were studied for the presence of retinal hemorrhages between 1-3 days of birth. The overall incidence of retinal hemorrhages was found to be 18.9%. It was observed that the incidence of retinal hemorrhages was higher in unassisted vaginal deliveries than in assisted births. A...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1989-02-01 00:00:00
abstract::In this study, 78 middle ear aspiration samples from 59 children between the ages of 2 14 who have undergone myringotomy under general anesthesia were included. The presence of DNA genome of Chlamydia trachomatis was analyzed with polymerase chain reaction in the aspiration material. The relationship between the natur...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2005-07-01 00:00:00
abstract:OBJECTIVE:We examined associations of different adiposity measures with cortisol responses during the Trier Social Stress Test for children (TSST-C). DESIGN:Descriptive study. SETTING:Holdsworth Memorial Hospital, Mysore, India. PARTICIPANTS:Adolescents aged 13.5y from a birth cohort were recruited (N=269, 133 boys)...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2018-02-15 00:00:00
abstract::Atypical celiac disease (ACD) presenting in childhood has rarely been documented from India. The present retrospective study analyzed features of atypical celiac disease over a 5-year period. Patients were diagnosed to have Celiac Disease (CD) as per the standard ESPGHAN criteria. The biochemical and hematological par...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2004-08-01 00:00:00
abstract:OBJECTIVE:To describe the utility of flexible fiberoptic bronchoscopy for the diagnosis and management in the neonatal ICU. METHODS:A retrospective, medical chart review was conducted in neonates who underwent flexible fiberoptic bronchoscopy over a period of 7 years. Besides demographic data and diagnostic findings, ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2019-07-15 00:00:00
abstract:OBJECTIVE:To identify the pattern of congenital heart defects (CHD) in children with Down Syndrome (DS) in an Omani population, and compare it with CHD in children without DS and with historical cohorts from populations with low prevalence of consanguinity. SETTING:Open-access Paediatric Echocardiography Clinic at Sul...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2003-05-01 00:00:00
abstract:JUSTIFICATION:Seizures constitute the most common neurological problem in children and the majority of epilepsy has its onset in childhood. Appropriate diagnosis and management of childhood epilepsy is essential to improve quality of life in these children. Evidence-based clinical practice guidelines, modified to the I...
journal_title:Indian pediatrics
pub_type: 杂志文章,实务指引
doi:
更新日期:2009-08-01 00:00:00
abstract::This paper explores the relationships between maternal weight, height and poor pregnancy outcome using a data set from a case-control study of low birth weight (LBW) and perinatal mortality in Ahmedabad, India. Maternal height and weights were compared between mothers of 611 perinatal deaths, 644 preterm-LBW, and 1465...
journal_title:Indian pediatrics
pub_type: 杂志文章,多中心研究
doi:
更新日期:1994-10-01 00:00:00
abstract::The discussion section explains the meaning of results to the readers, and addresses the implications of the findings emanating from the particular study. Authors should compare their results with previous reports, and attempt to explain similarities and differences. It is useful to outline the limitations and strengt...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-016-0955-4
更新日期:2016-10-08 00:00:00
abstract::Fifty two children were immunized with two doses of enhanced potency inactivated polio vaccine in order to determine its efficacy. The vaccine was very efficacious with 92.3, 92.3 and 88.3% of the children seroconverting to the three poliovirus types, respectively. The vaccine was equally efficacious whether the two d...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1992-11-01 00:00:00
abstract::Treatment of typhoid fever with furazolidone produces a high cure rate. This is a clinical curiosity, as furazolidone is described to be poorly absorbed. The present study examined whether furazolidone could produce unequivocal clinical response and, if so whether this was due to the drug producing bactericidal levels...
journal_title:Indian pediatrics
pub_type: 临床试验,杂志文章
doi:
更新日期:1995-05-01 00:00:00
abstract:OBJECTIVE:To study the clinical and biochemical spectrum of Gaucher disease. DESIGN:Assay of beta glucosidase enzyme in leucocytes in patients with splenomegaly, and in chorionic villi for prenatal diagnosis. SETTING:Hospital-based. SUBJECTS:Of 13 cases of Gaucher disease, aged 1-6 years, 9 were identified at Delhi ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1996-09-01 00:00:00
abstract::Antimicrobial resistance has become a global menace. As the resistance patterns and numbers are progressively increasing, it has become a major cause of morbidity and mortality in hospitalized patients, especially children. Efforts are being put world-over to curb the rising resistance by various means, especially by ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-016-0839-7
更新日期:2016-04-01 00:00:00
abstract::Avian flu is affecting the poultry animals world over since first outbreak in 1997 in Hong Kong and has resulted in 92 human deaths and culling of more than 150 million poultry animals in Asia and Europe. The loss to the economy has also been enormous. 13 new countries, including India, reported occurrence of the dise...
journal_title:Indian pediatrics
pub_type: 杂志文章,评审
doi:
更新日期:2006-04-01 00:00:00