Abstract：
OBJECTIVE:To study the clinical and biochemical spectrum of Gaucher disease. DESIGN:Assay of beta glucosidase enzyme in leucocytes in patients with splenomegaly, and in chorionic villi for prenatal diagnosis. SETTING:Hospital-based. SUBJECTS:Of 13 cases of Gaucher disease, aged 1-6 years, 9 were identified at Delhi and 4 at Bombay. RESULTS:The enzyme beta-glucosidase was 0.65 nmol/h/mg of protein or less in all the cases in Delhi, and 2.5 nmol/h/mg of protein or less in Bombay. All cases except one belonged to type 1 (hepatosplenomegaly), while one case was of type 2 (neuronopathic). Prenatal diagnosis was carried out in one family and the fetus was found to be affected. CONCLUSION:In children with hepatosplenomegaly and increased acid phosphatase, assay of beta-glucosidase enzyme confirms the diagnosis of Gaucher disease. Diagnosis of the disease is important because enzyme replacement therapy is available and prenatal diagnosis is possible.
journal_name
Indian Pediatrjournal_title
Indian pediatricsauthors
Kaur M,Kabra M,Kher A,Naik G,Bharucha BA,Verma ICsubject
Has Abstractpub_date
1996-09-01 00:00:00pages
735-8issue
9eissn
0019-6061issn
0974-7559journal_volume
33pub_type
杂志文章abstract：:Hospital acquired enteric infections were investigated by studying 3138 children under 5 years of age who were admitted without diarrhea in nine medical words of a pediatric hospital, Calcutta during the period between March and September 1987. Three hundred and twenty (10.2%) children developed nosocomial diarrhea du...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1993-02-01 00:00:00
abstract：:Trichotillomania, though uncommon, is one of the causes of unexplained hair loss, especially in children. Three girls in the age group of 4-6 years were observed in our pediatric dermatology clinic to have trichotillomania. In one child, there was co-existent alopecia areata. All were referred to the child guidance cl...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：:The clinical, angiographic and computed tomographic features in eight children with Moyamoya disease were evaluated. The CT Scan findings were correlated with the angiographic features and the stage of the vascular disease. Stenosis/occlusion of the supraclinoid internal carotid artery (ICA) and the proximal parts of ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1995-04-01 00:00:00
abstract：OBJECTIVE:To evaluate the effect of vitamin D and calcium supplementation for osteoprotection in thalassemia. METHODS:29 children (age 2-12 y) were supplemented with oral vitamin D (1000 IU/d) and calcium (500 mg/d) for 1 year. The dual energy X-ray absorptiometry (DXA) was done to assess bone mineral content at basel...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2019-04-15 00:00:00
abstract：:We report a case of toxic epidermal necrolysis who was successfully treated with intravenous immunoglobin and granulocyte colony-stimulating factor. He had poor prognostic factors such as extensive epidermal loss, neutropenia, acute respiratory distress syndrome and candida sepsis, but nonetheless made a complete reco...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2004-04-01 00:00:00
abstract：OBJECTIVE:To examine the catch up growth in severely wasted children using energy dense local foods at a hospital based nutrition rehabilitation unit. DESIGN:Retrospective cohort. SETTING:In-patient ward at a tertiary care government pediatric hospital in Hyderabad. PATIENTS:Children with severe malnutrition (n=309)...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-010-0101-7
更新日期：2010-08-01 00:00:00
abstract：OBJECTIVE:To compare the effectiveness of tepid sponging and antipyretic drug versus only antipyretic drug among febrile children. DESIGN:Randomized controlled trial. SETTING:Tertiary care hospital. PARTICIPANTS:150 children 6 mo - 12 yr age with axillary temperature 101F. INTERVENTION:Tepid sponging and antipyreti...
journal_title：Indian pediatrics
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2009-02-01 00:00:00
abstract：:In Kumbakonam, Tamil Nadu State in India, 384 final-year female students attending the Government College for Women completed a questionnaire so the researcher could assess their knowledge of prenatal and childhood immunizations, breast feeding, weaning, oral rehydration solution (ORS), and feeding during diarrhea. 5...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：:Twenty children of acute viral hepatitis were subjected to ultrasound of gall bladder in acute and recovery phase. Increased wall thickness, reduced volume and abnormal echo-texture of gall bladder contents were the findings in the acute phase. A normal ultrasound of gall bladder was restored in most of the patients w...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1989-07-01 00:00:00
abstract：OBJECTIVES:To generate evidence on the current situation of hospital care (emergency, inpatient and outpatient), for managing children presenting with diarrhea and pneumonia at 13 district hospitals in India. DESIGN:Facility-Based assessment of district hospitals. SETTINGS:13 district hospitals in four states of Biha...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2021-01-02 00:00:00
abstract：JUSTIFICATION:There is a need to revise/review recommendations regarding existing vaccines in view of current developments in vaccinology. PROCESS:Advisory Committee on Vaccines and Immunization Practices (ACVIP) of Indian Academy of Pediatrics (IAP) reviewed the new evidence, had two meetings, and representatives of ...
journal_title：Indian pediatrics
pub_type： 杂志文章,实务指引
doi：
更新日期：2018-12-15 00:00:00
abstract：:The discussion section explains the meaning of results to the readers, and addresses the implications of the findings emanating from the particular study. Authors should compare their results with previous reports, and attempt to explain similarities and differences. It is useful to outline the limitations and strengt...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-016-0955-4
更新日期：2016-10-08 00:00:00
abstract：:Fifty two mother-infant pairs were studied. Twenty six of these were delivered by the normal vaginal route (NVD group) and twenty six by Cesarean section (CS group). The NVD babies were roomed in with their mothers soon after birth whereas the CS babies had a mean separation of 2.8 +/- 1.0 days. The mother baby intera...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
abstract：:We performed a retrospective study of hospital records of children younger than 14 years with ocular trauma seen at our center in Sao Paulo, Brazil, between 2011 and 2012. From the total number of cases, 224 (89.2%) could be easily avoided. Accidents occurred with 5 children under 1 year of age; with one baby as young...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2020-12-26 00:00:00
abstract：OBJECTIVE:To evaluate the frequency of non-autoimmune subclinical and overt hypothyroidism in children with idiopathic steroid-resistant nephrotic syndrome (SRNS). METHODS:This cross-sectional study recruited 30 children (age 1-18 y) with idiopathic SRNS; and 30 healthy controls. Serum T3, T4 and TSH were performed in...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-017-1183-2
更新日期：2017-11-15 00:00:00
abstract：:Thrombocytosis is a frequent finding in hemograms obtained from hospitalized and ambulatory children due to the widespread use of automated blood cell counters. Pediatricians are commonly puzzled in cases of thrombocytosis to determine the underlying cause and the need for therapy. The purpose of this review is to ass...
journal_title：Indian pediatrics
pub_type： 杂志文章,评审
doi：
更新日期：2008-08-01 00:00:00
abstract：OBJECTIVE:To assess the epidemiological and clinical characteristics of pediatric inpatients with COVID-19, early in the pandemic. METHODS:Clinical and laboratory profile and outcomes were studied for children (aged 1 month - 18 years) presenting between 1 April, 2020 and 20 May, 2020 with positive nasopharyngeal swab...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2020-10-15 00:00:00
abstract：:There is a growing body of evidence over the last years suggesting continuous positive airway pressure (CPAP) ventilation being the first choice of ventilatory support in newborns with extremely low gestational age, and early rescue surfactant treatment being as effective as prophylactic therapy. The Intubation Surfac...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-015-0612-3
更新日期：2015-03-08 00:00:00
abstract：:We conducted this double blind randomized controlled trial to compare the rapid bronchodilator effect of salmeterol and formoterol in 60 children with stable asthma. Participants were randomized to receive either salmeterol (50 microg) (n=31) or formoterol (24 microg) (n=29) by metered dose inhaler and spacer. Spirome...
journal_title：Indian pediatrics
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2008-03-01 00:00:00
abstract：OBJECTIVE:To assess yield of MECP2 gene sequence variations analysis and large deletions in suspected cases of Rett syndrome. DESIGN:Descriptive study. SETTING:Tertiary-care medical genetics center. PATIENTS:Girls with neuroregression, postnatal microcephaly and signs and symptoms suggestive of classical and atypica...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2018-06-15 00:00:00
abstract：NEED AND PURPOSE OF REVIEW:A number of newer anti-epileptic drugs have been developed in the last few years to improve the treatment outcomes in epilepsy. In this review, we discuss the use of newer anti-epileptic drugs in children. METHODS USED FOR LOCATING, SELECTING, EXTRACTING AND SYNTHESIZING DATA:MEDLINE search ...
journal_title：Indian pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s13312-013-0284-9
更新日期：2013-11-08 00:00:00
abstract：OBJECTIVE:To assess the Vitamin A status of pregnant women in their third trimester using maternal serum retinol levels as the indicator; and (ii) To assess the impact of postpartum Vitamin A supplementation on the Vitamin A status of exclusively breastfed infants. DESIGN:Prospective randomized single blind controlled...
journal_title：Indian pediatrics
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2000-11-01 00:00:00
abstract：OBJECTIVE:To assess the effects of delayed cord clamping (DCC) on hemoglobin (Hb), mean corpuscular volume (MCV) and ferritin level in infants 2 months or older. EVIDENCE ACQUISITION:Meta-analysis of randomized control trials searched systematically from PubMed, Cochrane and Web of science. Trials published from Jan 1...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2020-09-15 00:00:00
abstract：:The International Classification of Functioning, Disability and Health (ICF) is a framework for describing health status; however, there is a gap in literature for supporting its use as a classification tool. The purpose of this paper is to provide a perspective on its use in describing children with cerebral palsy. T...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-016-0935-8
更新日期：2016-09-08 00:00:00
abstract：:Current Medical training in India is generally didactic and pedagogical, and often does not systematically prepare newly graduated doctors to be competent, confident and compassionate. After much deliberation, the Medical Council of India (MCI) has recently introduced a new outcome-driven curriculum for undergraduate ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2020-10-15 00:00:00
abstract：:A 13-year old girl presented with a decade long anemia, diffuse alveolar hemorrhage and interstistial lung disease; was eventually diagnosed as ANCA associated vasculitis. High index of suspicion is thus warranted for alternative diagnosis in chronic anemia, despite increased prevalence of infectious diseases and nutr...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-013-0042-z
更新日期：2013-02-01 00:00:00
abstract：:A random urine calcium/creatinine ratio (UCa/Cr) is of practical use in screening for hypercalciuria. However, due to worldwide variations, reference values for the pediatric population are not yet well established. Furthermore, no study has been conducted to establish normal UCa/Cr values in Turkish children. The obj...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2003-09-01 00:00:00
abstract：:A prospective study was performed on 44 patients (newborn to one year old) with acute bacterial meningitis. Sonograms were obtained within 72 hours of diagnosis, and repeated on 7th, 14th or at an early date, if required. The spectrum of sonographic features of meningitis included normal scan (35.4%), echogenic sulci ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1994-11-01 00:00:00
abstract：OBJECTIVE:To provide tribe- specific child mortality rates and health indicators from selected states in India. METHODS:We used Census 2011 data and Coale Demney methodology to estimate the infant mortality rate (IMR), under-five mortality rate (U5MR) and expectation of life at birth (LEB) for 123 tribes of selected s...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2021-01-15 00:00:00
abstract：BACKGROUND:Management of pyothorax and pneumothorax requires aspiration and/or intercostal drainage. CASE CHARACTERISTICS:We present two cases which were complicated by instrument-related events resulting in breakage of needle or intercostal drainage tube resulting in pleural foreign body. INTERVENTION/OUTCOME:The pa...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-016-0848-6
更新日期：2016-04-01 00:00:00
