Surfactant replacement therapy in extremely low gestational age newborns.

Abstract:

:There is a growing body of evidence over the last years suggesting continuous positive airway pressure (CPAP) ventilation being the first choice of ventilatory support in newborns with extremely low gestational age, and early rescue surfactant treatment being as effective as prophylactic therapy. The Intubation Surfactant Extubation procedure is discussed as an alternative procedure that may have the potential to combine the positive effects of surfactant and early CPAP. A further mode of surfactant administration, administration via a thin endotracheal catheter during spontaneous breathing with CPAP, has recently come into clinical use. This less invasive surfactant administration technique shows some short-term benefits but still cannot be recommended for general use in this vulnerable population. Long-term follow-up studies are needed to allow new recommendations on surfactant therapy in this high-risk population.

journal_name

Indian Pediatr

journal_title

Indian pediatrics

authors

Eibisberger M,Resch E,Resch B

doi

10.1007/s13312-015-0612-3

subject

Has Abstract

pub_date

2015-03-08 00:00:00

pages

227-30

issue

3

eissn

0019-6061

issn

0974-7559

journal_volume

52

pub_type

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