Immunogenicity of enhanced potency inactivated polio vaccine.

Abstract:

:Fifty two children were immunized with two doses of enhanced potency inactivated polio vaccine in order to determine its efficacy. The vaccine was very efficacious with 92.3, 92.3 and 88.3% of the children seroconverting to the three poliovirus types, respectively. The vaccine was equally efficacious whether the two doses were given at 4-week or 8-week intervals or when immunization was started at 6-7 weeks of age or later. The presence of maternal antibodies did not interfere significantly with the seroresponse to two doses of IPV-E. The study recommends that two doses of IPV-E give satisfactory seroconversion rates. Immunization can be started as early as 6 weeks age and the two doses can be given at 4 weeks interval to complete primary immunization against poliomyelitis.

journal_name

Indian Pediatr

journal_title

Indian pediatrics

authors

Singh J,Ravi RN,Dutta AK,Kumari S,Khare S

keywords:

subject

Has Abstract

pub_date

1992-11-01 00:00:00

pages

1353-6

issue

11

eissn

0019-6061

issn

0974-7559

journal_volume

29

pub_type

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