Abstract：
OBJECTIVE:To determine the clinical utility of serum neutrophil gelatinase-associated lipocalin (NGAL) as an early marker of acute kidney injury in asphyxiated neonates with hypoxic ischemic encephalopathy (HIE). DESIGN:Cohort study. SETTINGS:National Intensive Care Unit of Maternity Hospital, Ain Shams University, Cairo, Egypt. PATIENTS:The study included 30 term asphyxiated neonates (8 with mild, 13 with moderate and 9 with severe HIE) and 20 control neonates. INTERVENTION:Serum NGAL level was measured within 6 hours after birth using an enzyme linked immunosorbent assay. MAIN OUTCOME MEASURES:Patients were subsequently discriminated into AKI (n=12) and no-AKI (n=18) groups. RESULTS:The median (Interquartile range) serum NGAL concentration was 95.0 (70.75-180.00) ng/mL in asphyxiated neonates, and 39.75 (6.0-48.0) ng/mL in control neonates; (P<0.001). Serum NGAL correlated with HIE severity: mean (SD) was 65.50 (3.77) ng/mL in infants with mild HIE, 115.07 (45.83) ng/mL in infants with moderate HIE and 229.66 (79.50) ng/mL in infants with severe HIE; (P<0.01). The median (Interquartiles) serum NGAL level was 182.50 (166.25-301.75) ng/mL in patients with AKI, 74.00 (66.00-78.75) ng/mL in those without AKI; (P<0.001). A cutoff value 157 ng/mL for serum NGAL could detect AKI in asphyxiated neonates with a sensitivity of 83.3% and a specificity of 94.4%. CONCLUSION:Elevated serum NGAL measured within 6 hours after birth reliably indicates acute kidney injury in asphyxiated neonates.
journal_name
Indian Pediatrjournal_title
Indian pediatricsauthors
Raggal NE,Khafagy SM,Mahmoud NH,Beltagy SEdoi
10.1007/s13312-013-0153-6subject
Has Abstractpub_date
2013-05-08 00:00:00pages
459-62issue
5eissn
0019-6061issn
0974-7559pii
S097475591200659journal_volume
50pub_type
杂志文章abstract：:A study of infant feeding practices was carried out as part of a larger longitudinal study of an urban birth cohort in an area of South Delhi, India. 802 mothers of children over 1 year of age were selected randomly for interview. The study group is considered to be a representative sampling of the economic, cultura...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1976-11-01 00:00:00
abstract：:The prevalence of vitamin A deficiency was estimated in 366 rural children in the age group of 1 to 15 years. In a systematically selected subsample of 90 children, the dietary intake of vitamin A was assessed. The prevalence of vitamin A deficiency signs ranged from 24.1 to 34.8%. The adequacy of dietary intake of vi...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1990-05-01 00:00:00
abstract：OBJECTIVE:To compare the effectiveness of tepid sponging and antipyretic drug versus only antipyretic drug among febrile children. DESIGN:Randomized controlled trial. SETTING:Tertiary care hospital. PARTICIPANTS:150 children 6 mo - 12 yr age with axillary temperature 101F. INTERVENTION:Tepid sponging and antipyreti...
journal_title：Indian pediatrics
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2009-02-01 00:00:00
abstract：:Fifty two children were immunized with two doses of enhanced potency inactivated polio vaccine in order to determine its efficacy. The vaccine was very efficacious with 92.3, 92.3 and 88.3% of the children seroconverting to the three poliovirus types, respectively. The vaccine was equally efficacious whether the two d...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1992-11-01 00:00:00
abstract：BACKGROUND:Clinical presentations of intestinal lymphangiectasia include pitting edema, chylous ascites, pleural effusion, diarrhea, malabsorption and intestinal obstruction. CASE CHARACTERISTICS:An 8-year-old male child presented to the emergency department with clinical features of peritonitis, raising suspicion of ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2018-10-15 00:00:00
abstract：OBJECTIVE:To compare the effect of Kangaroo mother care (KMC) and conventional methods of care (CMC) on growth in LBW babies (> 2000 g). STUDY DESIGN:Randomized controlled trial. SETTING:Level III NICU of a teaching institution in western India. SUBJECTS:206 neonates with birth weight < 2000 g. INTERVENTION:The sub...
journal_title：Indian pediatrics
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2008-01-01 00:00:00
abstract：:This retrospective study was conducted to estimate the shedding of 2009 H1N1 virus and the risk analysis by review of medical charts, laboratory and radiological findings of all inpatients with confirmed pandemic influenza A (H1N1) at a provincial pediatric hospital. A total of 41 cases attending the inpatient departm...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-011-0151-5
更新日期：2011-12-01 00:00:00
abstract：:Association of rotavirus gastroenteritis with histo-blood group antigens in children younger than 5 years admitted with diarrhea (n=389) was studied. Distribution of blood groups in rotavirus positive (n=96) and rotavirus negative (n=51) diarrhea gastroenteritis cases did not show any susceptibility to any blood group...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2016-07-08 00:00:00
abstract：:A holistic approach in assessment and plan for intervention in childhood malnutrition is the need of the hour. This is in the context of nutrition education program (NEP), undertaken under the National IAP action plan, 2015. In the crusade against malnutrition, an ABCDEFQ assessment scale is recommended, with aspects ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-016-0820-5
更新日期：2016-03-01 00:00:00
abstract：:We evaluated 50 mothers of children with Down syndrome attending Genetic Clinic of the Institute of Child Health and Hospital for Children, Madras, with special reference to their knowledge, belief and attitudes in the care of these children. After evaluation, they were educated individually and in groups with demonst...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1991-09-01 00:00:00
abstract：OBJECTIVE:To determine the health-related quality of life in children with cerebral palsy and their families. METHODS:One hundred children (3-10 years of age) receiving regular rehabilitation therapy for cerebral palsy for last 1 year at a Child Development Centrer were enrolled and the Lifestyle assessment questionna...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-014-0414-z
更新日期：2014-05-01 00:00:00
abstract：:A 3.5-month-old infant with undiagnosed underlying combined immunodeficiency presented with S. ceravisiae fungemia following treatment with S. boulardii containing probiotic preparation. This case highlights that the use of probiotics in sick patients may be fraught with danger. ...
journal_title：Indian pediatrics
pub_type： 信件
doi：
更新日期：2019-11-15 00:00:00
abstract：OBJECTIVE:To assess the glycometabolic function in chronically transfused patients of beta- thalassemia major in terms of glucose tolerance, insulin secretion, insulin resistance index, and beta cell function index and to determine their relationship with clinical and biochemical profile. METHODS:30 homozygous thalass...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2006-05-01 00:00:00
abstract：:Twenty five asphyxiated neonates had ECG changes consistent with degree of asphyxia. Equivocal changes were found in mild asphyxia and changes suggestive of myocardial infarction were seen with severe asphyxia. In most cases, the changes reverted to normal within two weeks signifying great ability of the neonatal hear...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1990-11-01 00:00:00
abstract：OBJECTIVE:To evaluate endothelial function and arterial mechanics in apparently healthy overweight adolescents. DESIGN:Analytical observational study. SETTING:Tertiary hospital. METHODS:40 asymptomatic, normotensive and non-smoking adolescents (11 to 18 years old) were evaluated. Of these 20 were overweight or obese...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2004-11-01 00:00:00
abstract：BACKGROUND:Blue rubber bleb nevus syndrome is a rare clinical entity. CASE CHARACTERISTICS:A 13-year-old Indian boy presented with characteristic cutaneous lesions, gastrointestinal malformations, skeletal involvement and pulmonary stenosis. OBSERVATIONS:Diagnosis was confirmed on skin biopsy, radiographic evaluation...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-016-0884-2
更新日期：2016-06-08 00:00:00
abstract：:Fluconazole has been used as prophylaxis against systemic fungal infections in preterm neonates. We conducted a study to determine whether cessation of a policy of prophylactic fluconazole results in a resurgence of fungal infections in a unit. Neonates born in the 3 epoches: A 36-month pre-Fluconazole prophylaxis epo...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2005-12-01 00:00:00
abstract：OBJECTIVES:To develop age and gender specific waist circumference references for urban Indian children aged 3 -16 years. DESIGN:Cross-sectional study. SETTING:Urban preschools and schools of Bangalore. PARTICIPANTS:9060 children (5172 boys and 3888 girls) in the age group of 3-16 years. METHODS:Weight, height, and ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-011-0126-6
更新日期：2011-10-01 00:00:00
abstract：:The study population included 110 term healthy small-for-gestational age (SGA) infants having a blood sugar of > 30 mg/dl at the age of < 30 minutes. They were randomized into two groups; (a) Group I (study group) received sugar-fortified milk formula and (b) Group II (control group) received standard milk formula. A ...
journal_title：Indian pediatrics
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1992-11-01 00:00:00
abstract：OBJECTIVE:To study the transcutaneous absorption of traditionally massaged oil in newborns and to specifically compare the effects of (i) essential fatty acid (EFA) rich - safflower oil and (ii) saturated fat rich coconut oil, on fatty acid profiles of massaged babies. DESIGN:A short term randomised controlled study. ...
journal_title：Indian pediatrics
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2005-10-01 00:00:00
abstract：:Spinal muscular atrophy (SMA) represents the second most common fatal autosomal recessive disorder after cystic fibrosis. Due to the high carrier frequency, the burden of this genetic disorder is very heavy in developing countries like India. The aim was to study the clinical and molecular characteristics of patients ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-013-0168-z
更新日期：2013-06-08 00:00:00
abstract：CONTEXT:Cryptosporidium spp. is a zoonotic infection, now being recognized as a significant cause of diarrhea in both immunocompetent and immunocompromised hosts. However, there still exist significant knowledge gaps in its estimated global burden, epidemiology, diagnosis and management. EVIDENCE ACQUISITION:A semi-sy...
journal_title：Indian pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s13312-017-1093-3
更新日期：2017-04-15 00:00:00
abstract：:Growth monitoring (GM) in India is a strategy to detect early growth retardation, promote optimum growth, create awareness about growth among mothers, enhance delivery of primary health care, and identify those at risk of malnutrition. Anthropometric measures include weight, height, mid-upper arm circumference, chest ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1994-02-01 00:00:00
abstract：:Psychosocial assessment was carried out in 35 children with acute lymphatic leukemic, an equal number with non-leukemic chronic illness and their parents. Psychological dysfunction existed more frequently in parents of leukemic children. Depression as an initial reaction on being conveyed the diagnosis, was seen in 85...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1992-08-01 00:00:00
abstract：CONTEXT:Increased prevalence of obesity in childhood and adolescence, defined by the use of body mass index (BMI), has drawn attention towards direct measurement of body fat. OBJECTIVE:To develop age-and sex-specific reference distribution of body fat in apparently healthy North-Indian children in the age group of 7-1...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-013-0237-3
更新日期：2013-09-01 00:00:00
abstract：:Eighty one pregnant women (20 +/- 2 weeks of gestation) were assessed for their nutritional status. They were divided into three groups; Group I women (n = 30) were given 200 mg ferrous sulphate (FeSO4) tablet per day for 15 weeks, Group II women (n = 25) were given FeSO4 tablets along with 2,000,000 IU of vitamin A a...
journal_title：Indian pediatrics
pub_type： 临床试验,杂志文章
doi：
更新日期：1995-08-01 00:00:00
abstract：: ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2018-12-15 00:00:00
abstract：:Berardinelli-Seip congenital lipodystrophy (BSCL) is a very rare genetic disorder characterized by lipoatrophy, hypertriglyceridemia, hepatomegaly and acromegaloid features. On the basis of mutational and haplotype analysis, BSCL families have been classified into three types BSCL 1, BSCL2 and BSCLX. We report Berardi...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2006-05-01 00:00:00
abstract：:We conducted this study to find out the incidence of extubation failure (EF) in ventilated neonates and associated clinical risk factors. Eighty two ventilated neonates were followed up to 48 hours post extubation to look for EF. Twenty two babies (26.8%) had EF. The common risk factors for EF were presence of patent ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2009-10-01 00:00:00
abstract：:Increasing availability of DNA based tests in clinical practice has lead to widespread debate on the ethical issues involved. The wider usage of these tests in children has raised many questions regarding the ethics, validity of the request and its effects on childs psychosocial well-being. Though there have been much...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-013-0228-4
更新日期：2013-09-01 00:00:00
