Abstract:
CONTEXT:Cryptosporidium spp. is a zoonotic infection, now being recognized as a significant cause of diarrhea in both immunocompetent and immunocompromised hosts. However, there still exist significant knowledge gaps in its estimated global burden, epidemiology, diagnosis and management. EVIDENCE ACQUISITION:A semi-systematic search was performed across PubMed to select studies on epidemiological burden of cryptosporidium diarrhea using the following keywords- ['crytosporidiosis' OR 'cryptosporidium'] AND ['diarrhea' OR 'diarrhoea']. Articles were included if participants were 'Humans', belonged to pediatric (0-18 y) age group, and were published after 1990. The results were compiled separately for acute and persistent diarrhea. RESULTS:Cryptosporidium spp is commonly detected in stools of both cases (acute/ persistent diarrhea) and asymptomatic controls. The prevalence is higher in children with diarrhea than non-diarrheal controls (1.7-35% vs 0.3-15%); varying widely across different studies. The positivity rate is higher in younger children (<2 years) suffering from diarrhea. The main symptoms associated with cryptosporidiosis include fever, vomiting and abdominal pain with propensity for prolonged duration of diarrhea. It predisposes to malnutrition, which is also a risk factor for cryptosporidiosis. The prevalence is higher in HIV positive patients; certain socio-demographic factors play a more important role than mere geographical distribution for infection. CONCLUSION:The high positivity rates during both acute and persistent diarrhea highlights the need to suspect this infection even in immunocompetent children.
journal_name
Indian Pediatrjournal_title
Indian pediatricsauthors
Dabas A,Shah D,Bhatnagar S,Lodha Rdoi
10.1007/s13312-017-1093-3subject
Has Abstractpub_date
2017-04-15 00:00:00pages
299-309issue
4eissn
0019-6061issn
0974-7559journal_volume
54pub_type
杂志文章,评审abstract::Transfusion-related acute lung injury is a rare form of acute respiratory distress syndrome of possible immune etiology that develops immediately after a blood product transfusion. Clinicians need to be aware of this condition as prompt recognition and supportive management can prevent unwanted morbidity and mortality...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2012-02-01 00:00:00
abstract::An outbreak of suspected pertussis occurred in Sarli circle of Kurung-kumey district of Arunachal Pradesh in 2007. We investigated this outbreak to confirm the etiology, estimate the magnitude and identify reasons for its occurrence. Twenty-six deaths were reported from the circle. We identified 72 case-patients meeti...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2009-11-01 00:00:00
abstract::Ninety neonates were ventilated over a period of 33 months of whom 50 (55.5%) survived. Fifty seven babies received IPPV while 33 CPAP. IPPV mode was being used more frequently recently and survival rates have steadily improved over past 3 years. Survival was cent per cent in babies above 1.5 kg on CPAP mode while 16/...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1993-06-01 00:00:00
abstract::Decline in malnutrition levels has been dismal since the 1990s. We ascertained decadal trend in childhood nutritional status between 1997 and 2007 in Chandigarh, India and assessed impact of Integrated Child Development Services (ICDS) on childhood undernutrition. A total of 803 under-five children, 547 children betwe...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-011-0058-1
更新日期:2011-04-01 00:00:00
abstract::In 2009, India contributed to over half the global cases of poliomyelitis. Many believed that India would be the last country to be polio free. India proved them wrong and was certified polio free in 2014. In January 2016, India celebrated 5 years of being polio free. One of the major reasons behind the interruption o...
journal_title:Indian pediatrics
pub_type: 杂志文章,评审
doi:
更新日期:2016-08-07 00:00:00
abstract::In a randomized controlled design, 100 healthy, term neonates in the first week of life, undergoing heel prick for routine screening were randomized to receive a heel prick in either the drowsy/sleeping state or the awake (but not fussy or crying) state. 48 babies in sleeping or drowsy states and 47 in the awake state...
journal_title:Indian pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1007/s13312-011-0082-1
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVE:To describe a novel wrist deformity in b-thalassemia major patients, and their radiographic and magnetic resonance imaging findings. METHODS:30 patients with b-thalassemia major who were noticed to have ulnar deviation at wrist joint were evaluated for previous history of medications, serum ferritin levels, ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2019-01-15 00:00:00
abstract::Two hundred and fifty eight newborn babies were studied for the presence of retinal hemorrhages between 1-3 days of birth. The overall incidence of retinal hemorrhages was found to be 18.9%. It was observed that the incidence of retinal hemorrhages was higher in unassisted vaginal deliveries than in assisted births. A...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1989-02-01 00:00:00
abstract:OBJECTIVE:Comparison of the clinical efficacy of a transparent, DPI (transparent Rotahaler) with MDI and spacers in childhood asthma. DESIGN:Open, randomized, crossover trial. SETTINGS:Out patient clinic of a referral pediatric center. METHODS:Thirty (mean 6.1 +/-2.7 years) children with moderate persistent asthma w...
journal_title:Indian pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2001-01-01 00:00:00
abstract::A cross sectional study was conducted in 260 adolescent schoolchildren (114 males) in the age group of 11-18 years to estimate the prevalence of zinc deficiency in the National Capital Territory of Delhi. Serum zinc was estimated using Inductively coupled plasma mass spectrometer. Overall, 49.4% children (50.8% males,...
journal_title:Indian pediatrics
pub_type: 信件
doi:
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND:Improved survival seen in Acute Lymphoblastic Leukemia (ALL) cases has led to increased reports of second malignant neoplasms. CASE CHARACTERISTICS:A 12-year-old female treated for ALL using UK ALL XI protocol nine years back presented with progressively increasing pre-auricular swelling. OBSERVATION:Inves...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-015-0757-0
更新日期:2015-11-01 00:00:00
abstract::Indian Pediatrics limited the number of authorship to 5, 4 and 2 for Brief Reports (BR), Case Reports (CR), and Letters to the Editor (LE), respectively from January 2003, to curb gift authorship. To analyze the impact of this policy, a comparative analysis was conducted for years 2002-2004. Mean (SD) number of author...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract::The present study was undertaken to find out the best simple anthropometric parameter for identifying low birth weight babies (LBW). A total of 1000 newborn babies were subjected to anthropometry within 48 hours of life. Birth weight was significantly correlated (p less than 0.001) with thigh circumference (TC), mid-a...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract:OBJECTIVE:To examine the catch up growth in severely wasted children using energy dense local foods at a hospital based nutrition rehabilitation unit. DESIGN:Retrospective cohort. SETTING:In-patient ward at a tertiary care government pediatric hospital in Hyderabad. PATIENTS:Children with severe malnutrition (n=309)...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-010-0101-7
更新日期:2010-08-01 00:00:00
abstract::The study population included 110 term healthy small-for-gestational age (SGA) infants having a blood sugar of > 30 mg/dl at the age of < 30 minutes. They were randomized into two groups; (a) Group I (study group) received sugar-fortified milk formula and (b) Group II (control group) received standard milk formula. A ...
journal_title:Indian pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1992-11-01 00:00:00
abstract::30 MEDLINE indexed Indian journals publishing clinical trials were identified and their editorial policies on trial registration were assessed. Trial registration number was required in 9 journals (30%).16 journals (53.33%) encouraged adherence to the CONSORT Statement, while 22 (73.33%) mentioned ICMJE Guidelines. ...
journal_title:Indian pediatrics
pub_type: 信件
doi:10.1007/s13312-013-0092-2
更新日期:2013-03-01 00:00:00
abstract:OBJECTIVE:Gaucher disease in India has been reported only in a few case reports from India. The aim of the study was to assess the response to enzyme replacement therapy in Indian patients with Gaucher disease. DESIGN:Retrospective analysis of patients receiving CHO-derived recombinant macrophage-targetted glucocorebr...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-011-0128-4
更新日期:2011-10-01 00:00:00
abstract::A retrospective analysis was carried out to identify factors associated with delay in diagnosis of Kawasaki disease in a tertiary care pediatric hospital setting in Chennai, India. Over a period of 2 years, a total of 37 cases were studied. The cases were divided into Early Diagnosis Group (EDG) and Delayed Diagnosis ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-012-0130-5
更新日期:2012-08-01 00:00:00
abstract:OBJECTIVE:To evaluate the profile of children with central diabetes insipidus (DI) and identify factors indicating organic etiology. DESIGN:Retrospective chart review. SETTING:Tertiary referral hospital. SUBJECTS:Fifty-nine children with central DI (40 boys, 19 girls). METHODS:Features of organic and idiopathic cen...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2008-06-01 00:00:00
abstract:OBJECTIVE:To determine whether interactional group discussions could reduce prescriptions of injections by physicians. STUDY DESIGN:Randomized controlled trial. SETTING:Rural public health care facilities, North 24 Parganas district, West Bengal, India. SUBJECTS:72 medical officers, 36 each in intervention and contr...
journal_title:Indian pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1007/s13312-010-0076-4
更新日期:2010-05-01 00:00:00
abstract::Twenty children of acute viral hepatitis were subjected to ultrasound of gall bladder in acute and recovery phase. Increased wall thickness, reduced volume and abnormal echo-texture of gall bladder contents were the findings in the acute phase. A normal ultrasound of gall bladder was restored in most of the patients w...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1989-07-01 00:00:00
abstract:OBJECTIVE:To assess the effects of delayed cord clamping (DCC) on hemoglobin (Hb), mean corpuscular volume (MCV) and ferritin level in infants 2 months or older. EVIDENCE ACQUISITION:Meta-analysis of randomized control trials searched systematically from PubMed, Cochrane and Web of science. Trials published from Jan 1...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2020-09-15 00:00:00
abstract::Anthropometric data from our survey of 1,879 children in Madhya Pradesh revealed low sensitivity (17.5%) and positive predictive value (30.4%) of Mid-Upper Arm Circumference (MUAC) at the recommended cut-off of 115 mm for identifying Severe Acute Malnutrition (SAM). This led us to question the reliability of MUAC as a...
journal_title:Indian pediatrics
pub_type: 信件
doi:10.1007/s13312-013-0032-1
更新日期:2013-01-08 00:00:00
abstract::Marfan syndrome rarely presents with peripheral artery and pulmonary artery aneurysms. We are presenting a case of a fifteen-year-old boy who presented to us with progressive lower abdominal pulsatile swelling with bruit in the right inguinal region for one month. He had typical marfanoid habitus, though there was no ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2013-05-08 00:00:00
abstract:OBJECTIVE:To compare the efficacy of artemether and quinine in the treatment of severe malaria in hospitalized children. STUDY DESIGN:Open randomized trial. SETTING:Pediatric ward of a tertiary care center. METHODS:All children admitted with clinical manifestations of severe malaria (as per WHO criteria) and asexual...
journal_title:Indian pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2003-10-01 00:00:00
abstract:OBJECTIVE:To evaluate the frequency of non-autoimmune subclinical and overt hypothyroidism in children with idiopathic steroid-resistant nephrotic syndrome (SRNS). METHODS:This cross-sectional study recruited 30 children (age 1-18 y) with idiopathic SRNS; and 30 healthy controls. Serum T3, T4 and TSH were performed in...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-017-1183-2
更新日期:2017-11-15 00:00:00
abstract:BACKGROUND:Blue rubber bleb nevus syndrome is a rare clinical entity. CASE CHARACTERISTICS:A 13-year-old Indian boy presented with characteristic cutaneous lesions, gastrointestinal malformations, skeletal involvement and pulmonary stenosis. OBSERVATIONS:Diagnosis was confirmed on skin biopsy, radiographic evaluation...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-016-0884-2
更新日期:2016-06-08 00:00:00
abstract:BACKGROUND:Neuroschistosomiasis is an uncommonly reported disease. CASE CHARACTERISTICS:An adolescent Indian boy residing in Kenya presented with headache, visual symptoms and seizures, with MRI showing space-occupying lesions in the occipital lobe and cerebellum. OBSERVATION:Brain biopsy was diagnostic of neuro-schi...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2018-11-15 00:00:00
abstract:Background:We describe the demographic, clinical and labo-ratory findings along with the treatment and outcomes among children meeting the case definition of Pediatric Inflammatory Multisystem Syndrome - Temporally associated with SARS-CoV-2 (PIMS-TS). METHODS:We analyzed the clinical and laboratory findings of childr...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2020-11-15 00:00:00
abstract::The prevalence of vitamin A deficiency was estimated in 366 rural children in the age group of 1 to 15 years. In a systematically selected subsample of 90 children, the dietary intake of vitamin A was assessed. The prevalence of vitamin A deficiency signs ranged from 24.1 to 34.8%. The adequacy of dietary intake of vi...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1990-05-01 00:00:00