Abstract:
CONTEXT:Cryptosporidium spp. is a zoonotic infection, now being recognized as a significant cause of diarrhea in both immunocompetent and immunocompromised hosts. However, there still exist significant knowledge gaps in its estimated global burden, epidemiology, diagnosis and management. EVIDENCE ACQUISITION:A semi-systematic search was performed across PubMed to select studies on epidemiological burden of cryptosporidium diarrhea using the following keywords- ['crytosporidiosis' OR 'cryptosporidium'] AND ['diarrhea' OR 'diarrhoea']. Articles were included if participants were 'Humans', belonged to pediatric (0-18 y) age group, and were published after 1990. The results were compiled separately for acute and persistent diarrhea. RESULTS:Cryptosporidium spp is commonly detected in stools of both cases (acute/ persistent diarrhea) and asymptomatic controls. The prevalence is higher in children with diarrhea than non-diarrheal controls (1.7-35% vs 0.3-15%); varying widely across different studies. The positivity rate is higher in younger children (<2 years) suffering from diarrhea. The main symptoms associated with cryptosporidiosis include fever, vomiting and abdominal pain with propensity for prolonged duration of diarrhea. It predisposes to malnutrition, which is also a risk factor for cryptosporidiosis. The prevalence is higher in HIV positive patients; certain socio-demographic factors play a more important role than mere geographical distribution for infection. CONCLUSION:The high positivity rates during both acute and persistent diarrhea highlights the need to suspect this infection even in immunocompetent children.
journal_name
Indian Pediatrjournal_title
Indian pediatricsauthors
Dabas A,Shah D,Bhatnagar S,Lodha Rdoi
10.1007/s13312-017-1093-3subject
Has Abstractpub_date
2017-04-15 00:00:00pages
299-309issue
4eissn
0019-6061issn
0974-7559journal_volume
54pub_type
杂志文章,评审abstract:OBJECTIVE:To evaluate adiponectin levels in children and adolescents with type I diabetes, and their relationship to long term complications. DESIGN:Cross sectional. SETTING:Tertiary referral hospital, Cairo, Egypt. PARTICIPANTS:Thirty children and adolescents with type I diabetes mellitus, classified into complicat...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-012-0041-5
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND:Glycogen storage disease type VI (GSD-VI) presents with failure to thrive and also fibrosis in some cases, without cirrhosis. CASE CHARACTERISTICS:2½-year-old girl presented with short stature, transaminase elevation and significant fibrosis, suggesting GSD-III. OBSERVATION:A pathogenic mutation in PYGL ge...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-017-1174-3
更新日期:2017-09-15 00:00:00
abstract:OBJECTIVE:To evaluate endothelial function and arterial mechanics in apparently healthy overweight adolescents. DESIGN:Analytical observational study. SETTING:Tertiary hospital. METHODS:40 asymptomatic, normotensive and non-smoking adolescents (11 to 18 years old) were evaluated. Of these 20 were overweight or obese...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2004-11-01 00:00:00
abstract::In 2009, India contributed to over half the global cases of poliomyelitis. Many believed that India would be the last country to be polio free. India proved them wrong and was certified polio free in 2014. In January 2016, India celebrated 5 years of being polio free. One of the major reasons behind the interruption o...
journal_title:Indian pediatrics
pub_type: 杂志文章,评审
doi:
更新日期:2016-08-07 00:00:00
abstract:OBJECTIVE:To compare lipid parameters between diabetics and controls and to study association between metabolic control and lipid profile. METHODS:Lipid profile and HbA1c were measured (n=80, 39 boys) in diabetic children [age 10.7(3.4) y] and 54 controls, tests repeated after 1 year (in 45 diabetics). RESULTS:Diabet...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-016-0787-2
更新日期:2016-01-01 00:00:00
abstract::This presentation deals with 110 surgically proven cases of abdominal tuberculosis in the pediatric age group. The protean clinical profiles and complications of the disease entity made the clinical diagnosis difficult; the investigations were also found non-pathognomonic. The most common type of pathology seen was ad...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1993-09-01 00:00:00
abstract::We conducted this study to determine the fatty acid composition of breastmilk of Israeli women and compare it with baby milk substitutes. Samples of mature breast milk, from 29 lactating Israeli Jewish mothers were collected during feedings. Total milk lipids extracts were transmethylated and analyzed by using an impr...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-013-0277-8
更新日期:2013-11-08 00:00:00
abstract::Congenital hypoparathyroidism, growth retardation and dysmorphism is a rare autosomal recessive syndrome among Arab population commonly known as Sanjad-Sakati syndrome(SSS).Several metabolic and septic complications are known to manifest in the neonatal age. We describe the first report of morbid pathological fracture...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-010-0066-6
更新日期:2010-05-01 00:00:00
abstract::We studied the actual time taken to document temperature in a stable neonate by an electronic digital skin thermometer with automatic time beeper. We studied 100 neonates after initial stabilization. The mean time required for documenting the temperature by a electronic thermometer in axilla was 56.34+/-1.54 secs for ...
journal_title:Indian pediatrics
pub_type: 信件
doi:
更新日期:2009-12-01 00:00:00
abstract:: ...
journal_title:Indian pediatrics
pub_type: 评论,社论
doi:
更新日期:2018-11-15 00:00:00
abstract::The incidence and the factors that influence twinning were studied in six villages of Dholka Taluka, a rural field training centre. The twinning rate was 10.10 per 1000 maternities. The monozygotic and dizygotic twinning rates were 4.53 and 5.56, respectively by applying Weinberg's differential formula. In three fourt...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1990-03-01 00:00:00
abstract:OBJECTIVE:To examine the benefits of anemia prophylaxis in adolescent school.girls by weekly or daily iron-folate supplementation. DESIGN:Prospective study. SETTING:Government girl schools of northeast Delhi. SUBJECTS:2088 subjects (with hemoglobin greater than 7.9 g/dL), including 702 on daily and 695 on weekly iro...
journal_title:Indian pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2003-04-01 00:00:00
abstract::Pediatric coronavirus disease-19 (COVID-19) infection is relatively mild when compared to adults, and children are reported to have a better prognosis. Mortality in children appears rare. Clinical features of COVID-19 in children include fever and cough, but a large proportion of infected children appears to be asympt...
journal_title:Indian pediatrics
pub_type: 杂志文章,评审
doi:
更新日期:2020-05-15 00:00:00
abstract:CONTEXT:Measles remains a major cause of child mortality in India. Measles case fatality ratios (CFRs) vary substantially between countries and even within the same community over time. We present a review of Indian community-based measles CFR studies conducted from 1975 to 2008. EVIDENCE ACQUISITION:PubMed, Cochrane ...
journal_title:Indian pediatrics
pub_type: 杂志文章,评审
doi:
更新日期:2009-11-01 00:00:00
abstract:OBJECTIVE:To determine the clinical utility of serum neutrophil gelatinase-associated lipocalin (NGAL) as an early marker of acute kidney injury in asphyxiated neonates with hypoxic ischemic encephalopathy (HIE). DESIGN:Cohort study. SETTINGS:National Intensive Care Unit of Maternity Hospital, Ain Shams University, C...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-013-0153-6
更新日期:2013-05-08 00:00:00
abstract::Twenty five asphyxiated neonates had ECG changes consistent with degree of asphyxia. Equivocal changes were found in mild asphyxia and changes suggestive of myocardial infarction were seen with severe asphyxia. In most cases, the changes reverted to normal within two weeks signifying great ability of the neonatal hear...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1990-11-01 00:00:00
abstract::Sixty children with acute bacterial meningitis (ABM) were prospectively studied for their serum sodium values and cerebrospinal fluid (CSF), serum and urinary osmolality. The results have been compared with 20 age and nutritionally matched controls. Even though mean serum osmolality (283.2 +/- 13.84 mOsm/kg) and serum...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1993-10-01 00:00:00
abstract::A pilot study was undertaken to develop a feasible neonatal screening strategy for hemoglobinopathies. Isoelectric focusing using dried blood spots samples as a primary screening technique was standardized for the first time in India. The screened positives were confirmed by high performance liquid chromatography foll...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2011-02-01 00:00:00
abstract::We assessed the clinical response and side effects of Ferrous sulfate (FS) and Iron polymaltose complex (IPC) in 118 children with Iron deficiency anemia (IDA). Subjects were randomized to receive therapy with either oral IPC (Group A, n=59) or oral FS (Group B, n=59); all were given elemental iron in three divided do...
journal_title:Indian pediatrics
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2009-10-01 00:00:00
abstract:OBJECTIVE:Analyze the profile and outcome of children with rhabdomyosarcoma from a pediatric-oncology unit. DESIGN:Retrospective analysis of case records over 23 years (1990-2012). Setting:Government-run, tertiary-care, university hospital in Northern India. PARTICIPANTS:159 children (<12-years) with a diagnosis of ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-017-1164-5
更新日期:2017-09-15 00:00:00
abstract::A case control study was conducted in a referral and teaching hospital in North India on children aged 2 months to 5 years, to compare blood zinc levels in 50 cases of severe pneumonia and 50 age,sex and nutritional status matched controls. Mean blood Zinc levels in cases and controls was 376.1 ug/dL + 225.73 and 538....
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2004-05-01 00:00:00
abstract:OBJECTIVE:To evaluate the effect of canakinumab on growth parameters of patients with autoinflammatory diseases. METHODS:This retrospective study included Colchicine resistant familial Mediterranean fever (FMF), Mevalonate kinase deficiency (MKD), Tumor necrosis factor receptor-associated periodic fever syndrome (TRAP...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2020-07-15 00:00:00
abstract:BACKGROUND:Lipoid pneumonia is a rare form of pneumonia caused by aspiration of fatty substances. CASE CHARACTERISTICS:Acute respiratory distress syndrome in an infant due to accidental aspiration of baby oil massage. INTERVENTION:Large volume bronchoalveolar lavage. OUTCOME:Gradual recovery over a period of 5 month...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-015-0569-2
更新日期:2015-01-01 00:00:00
abstract::The present study was undertaken to find out the best simple anthropometric parameter for identifying low birth weight babies (LBW). A total of 1000 newborn babies were subjected to anthropometry within 48 hours of life. Birth weight was significantly correlated (p less than 0.001) with thigh circumference (TC), mid-a...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the current spectrum of hepatobiliary disorders in children in Northern India. SETTING:Tertiary level referral hospital. METHODS:All children with hepatobiliary disorders presenting between January 1992 through July 1995 were evaluated by clinical assessment, liver function tests, viral and auto...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1997-10-01 00:00:00
abstract::Primary immunodeficiency disorders (PIDs) are a heterogeneous group of inherited disorders that affect different components of the immune system. There are more than 150 different disorders which have been described till date. Despite major advances in the molecular characterization of PIDs over the last 20 years, man...
journal_title:Indian pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s13312-013-0171-4
更新日期:2013-06-08 00:00:00
abstract::Avian flu is affecting the poultry animals world over since first outbreak in 1997 in Hong Kong and has resulted in 92 human deaths and culling of more than 150 million poultry animals in Asia and Europe. The loss to the economy has also been enormous. 13 new countries, including India, reported occurrence of the dise...
journal_title:Indian pediatrics
pub_type: 杂志文章,评审
doi:
更新日期:2006-04-01 00:00:00
abstract::We report a 12-year-old child with pseudohypoparathyroidism (PHP) whose mother had pseudopseudohypoparathyroidism. The child had low serum calcium, high phosphorous and high parathormone (PTH) levels. PHP occurs due to a defect in the guanine nucleotide binding protein (G protein). She also had hypothyroidism which is...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-012-0225-z
更新日期:2012-12-01 00:00:00
abstract:OBJECTIVES:To develop age and gender specific waist circumference references for urban Indian children aged 3 -16 years. DESIGN:Cross-sectional study. SETTING:Urban preschools and schools of Bangalore. PARTICIPANTS:9060 children (5172 boys and 3888 girls) in the age group of 3-16 years. METHODS:Weight, height, and ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-011-0126-6
更新日期:2011-10-01 00:00:00
abstract::Thirty six neonates with severe birth asphyxia (Apgar score less than or equal to 3 at 1 min), 32 with moderate birth asphyxia (Apgar score 4 to 6 at 1 min) and 35 controls (Apgar score greater than or equal to 7 at 1 min) matched for weight and gestation were followed up prospectively for neurodevelopmental outcome. ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1989-08-01 00:00:00