Abstract:
:Pediatric coronavirus disease-19 (COVID-19) infection is relatively mild when compared to adults, and children are reported to have a better prognosis. Mortality in children appears rare. Clinical features of COVID-19 in children include fever and cough, but a large proportion of infected children appears to be asymptomatic and may contribute to transmission. It remains unclear why children and young adults are less severely affected than older individuals, but this might involve differences in immune system function in the elderly and/or differences in the expression/function of the cellular receptor for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)- Angiotensin converting enzyme 2 (ACE2). Laboratory findings and chest imaging may not be specific in children with COVID-19. Diagnosis is by Reverse transcriptase-Polymerase chain reaction (RT-PCR) testing of upper or lower respiratory tract secretions. This review additionally considers COVID-19 in immunosuppressed children, and also suggests a management algorithm for the few children who appear to present with life threatening infection, including the potential use of antiviral and immunomodulatory treatment. The most significant threat to global child health from SARS-CoV-2 is unlikely to be related to COVID 19 in children, but rather the socio-economic consequences of a prolonged pandemic.
journal_name
Indian Pediatrjournal_title
Indian pediatricsauthors
Balasubramanian S,Rao NM,Goenka A,Roderick M,Ramanan AVsubject
Has Abstractpub_date
2020-05-15 00:00:00pages
435-442issue
5eissn
0019-6061issn
0974-7559pii
S097475591600159journal_volume
57pub_type
杂志文章,评审abstract::Jaundice as a presenting feature of pediatric acute myeloid leukemia is rare. We report two cases of AML who presented with obstructive jaundice, one with a malignant stricture at the common bile duct and other with a granulocytic sarcoma obstructing the bile duct. The prognosis is poor in these patients. ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2012-05-01 00:00:00
abstract:OBJECTIVE:To estimate the prevalence of Iodine Deficiency Disorders, and household consumption of adequately iodized salt in Damoh district, Madhya Pradesh in 2016. METHODS:Cross-sectional study with cluster sampling method was used among school-going children. 30 clusters, each with 90 children were selected to acces...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2018-07-15 00:00:00
abstract:OBJECTIVES:To identify important factors (linked to lifestyle, eating and sedentary behaviors) relating to waist circumference among urban South Indian children aged 3 to 16 years. DESIGN:Cross sectional. SETTING:Urban schools of Bangalore, from August 2008 to January 2010. PARTICIPANTS:8444 children; 4707 children ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-012-0027-3
更新日期:2012-02-01 00:00:00
abstract:NEED AND PURPOSE OF REVIEW:A number of newer anti-epileptic drugs have been developed in the last few years to improve the treatment outcomes in epilepsy. In this review, we discuss the use of newer anti-epileptic drugs in children. METHODS USED FOR LOCATING, SELECTING, EXTRACTING AND SYNTHESIZING DATA:MEDLINE search ...
journal_title:Indian pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s13312-013-0284-9
更新日期:2013-11-08 00:00:00
abstract::Twenty five to thirty per cent of all patients admitted with head injuries to any large hospital are children. Head injuries in children differ in several ways from those seen in the adult population. A standard management protocol is used in a service hospital and CT and neurosurgical consultation/transfer is based o...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1994-06-01 00:00:00
abstract:: ...
journal_title:Indian pediatrics
pub_type: 评论,杂志文章
doi:
更新日期:2019-09-15 00:00:00
abstract::This retrospective study was conducted to estimate the shedding of 2009 H1N1 virus and the risk analysis by review of medical charts, laboratory and radiological findings of all inpatients with confirmed pandemic influenza A (H1N1) at a provincial pediatric hospital. A total of 41 cases attending the inpatient departm...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-011-0151-5
更新日期:2011-12-01 00:00:00
abstract::Neural tube defects (NTD) comprise of a group of congenital malformations that include spina bifida, anencephaly and encephalocele. Reports have implicated zinc deficiency as one of the causative factors of NTDs. We compared the serum zinc level of 23 newborns having neural tube defects with 35 healthy controls by spe...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2006-09-01 00:00:00
abstract:OBJECTIVE:To determine whether interactional group discussions could reduce prescriptions of injections by physicians. STUDY DESIGN:Randomized controlled trial. SETTING:Rural public health care facilities, North 24 Parganas district, West Bengal, India. SUBJECTS:72 medical officers, 36 each in intervention and contr...
journal_title:Indian pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1007/s13312-010-0076-4
更新日期:2010-05-01 00:00:00
abstract:OBJECTIVE:To assess the levels of free oxygen radicals in acute renal failure and their predictive value in clinical outcome. DESIGN:Prospective. SETTING:Intensive care unit. METHODS:Study was conducted in 50 children (25 with acute renal failure and 25 age and sex matched controls). Blood urea, serum creatinine, se...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2000-02-01 00:00:00
abstract:OBJECTIVE:To evaluate serum leptin levels in obese Indian children and its correlation to anthropometric and biochemical parameters. DESIGN:Cohort study. SETTING:Referral tertiary hospital. METHODOLOGY:Leptin levels were measured in 36 children (26 boys, age 1.5 to 15 years) and 37 adults (21 men, age 25 to 69 years...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2007-04-01 00:00:00
abstract:OBJECTIVE:To evaluate simple clinical signs of illness in young infants (0 to 2 months) and to correlate with WHO IMCI algorithm (7 days-2 months). DESIGN:Prospective observational. Study conducted in the outpatient department and emergency room of a pediatric tertiary level hospital. METHODS:Four hundred and ninety ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2006-12-01 00:00:00
abstract:OBJECTIVE:To evaluate the efficacy and tolerability of intravenous fosphenytoin in children with status epilepticus, and resulting serum total phenytoin levels. METHODS:In this prospective study, 51 children aged less than 18 years received intravenous loading dose of fosphenytoin (18-20 mg/kg). Serum total phenytoin ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2020-03-15 00:00:00
abstract:OBJECTIVE:To evaluate the current spectrum of hepatobiliary disorders in children in Northern India. SETTING:Tertiary level referral hospital. METHODS:All children with hepatobiliary disorders presenting between January 1992 through July 1995 were evaluated by clinical assessment, liver function tests, viral and auto...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1997-10-01 00:00:00
abstract::Twenty six perinatally acquired HAART naive HIV positive children asymptomatic for cardiac disease in age group of 1-9 years were evaluated for cardiac abnormalities by echocardiography. All children were classified according to the revised CDC classification for HIV infection in children. 20 (76.9 percent) patients h...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2005-02-01 00:00:00
abstract::Hepatic abscess in a neonate is a rare but serious disorder. Diagnosis of hepatic abscess requires a high index of suspicion in any septic neonate. CT scan and ultrasound of liver are the most sensitive diagnostic tests in detection of hepatic abscess. Portal vein thrombosis and portal cavernoma formation is hitherto ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2003-10-01 00:00:00
abstract:OBJECTIVE:To assess the Vitamin A status of pregnant women in their third trimester using maternal serum retinol levels as the indicator; and (ii) To assess the impact of postpartum Vitamin A supplementation on the Vitamin A status of exclusively breastfed infants. DESIGN:Prospective randomized single blind controlled...
journal_title:Indian pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2000-11-01 00:00:00
abstract::We evaluated 50 mothers of children with Down syndrome attending Genetic Clinic of the Institute of Child Health and Hospital for Children, Madras, with special reference to their knowledge, belief and attitudes in the care of these children. After evaluation, they were educated individually and in groups with demonst...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1991-09-01 00:00:00
abstract:OBJECTIVE:To assess the safety and reactogenecity of indigenously produced measles vaccine derived from EZ strain. DESIGN:A longitudinal clinical follow up after vaccination. SETTING:Hospital based and home follow up, as required. SUBJECTS:12,470 children, 9 to 15 months old, immunized with measles vaccine of EZ str...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1996-10-01 00:00:00
abstract::We studied the level of food insecurity among households with HIV-infected children and its relationship with childhood nutritional indicators. Among the 147 children assessed, food insecurity was present in 59% of households. Majority of children with stunting belonged to-food insecure families. Stunting and Underwei...
journal_title:Indian pediatrics
pub_type: 信件
doi:
更新日期:2015-03-08 00:00:00
abstract::Pediatric statistics in a 50-year-old large hospital were analysed to find out any change in pediatric admission rate, morbidity and mortality and outcome of common disorders during the last four decades. Information was collected from four block years from each of the last four decades and compared. An increase of al...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1991-03-01 00:00:00
abstract::We report a case of toxic epidermal necrolysis who was successfully treated with intravenous immunoglobin and granulocyte colony-stimulating factor. He had poor prognostic factors such as extensive epidermal loss, neutropenia, acute respiratory distress syndrome and candida sepsis, but nonetheless made a complete reco...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2004-04-01 00:00:00
abstract::The skinfold thickness (SFT) was measured in 750 Punjabi newborns at triceps and subscapular sites using a Harpenden's Caliper. It was correlated with various maternal and neonatal factors. SFT increased with increasing gestation but showed a decline after 40 weeks. There was a positive correlation of SFT with birth w...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1991-11-01 00:00:00
abstract:OBJECTIVE:We examined associations of different adiposity measures with cortisol responses during the Trier Social Stress Test for children (TSST-C). DESIGN:Descriptive study. SETTING:Holdsworth Memorial Hospital, Mysore, India. PARTICIPANTS:Adolescents aged 13.5y from a birth cohort were recruited (N=269, 133 boys)...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2018-02-15 00:00:00
abstract::A 3.5-month-old infant with undiagnosed underlying combined immunodeficiency presented with S. ceravisiae fungemia following treatment with S. boulardii containing probiotic preparation. This case highlights that the use of probiotics in sick patients may be fraught with danger. ...
journal_title:Indian pediatrics
pub_type: 信件
doi:
更新日期:2019-11-15 00:00:00
abstract::We report a 71/2-year-boy with disseminated systemic cryptococcosis. Although other species have been incriminated, this appears to be the first report of Cryptococcus humicolus. The child was HIV negative. He was treated with amphotericin B and fluconazole with intensive supportive care. The child responded after 6 w...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2004-11-01 00:00:00
abstract::Hypocalcemia is a curable cause of myocardial dysfunction and clinical congestive cardiac failure, with only stray reports available in literature. We describe 15 infants presenting with severe left ventricular dysfunction, who were found to have hypocalcemia with or without hypomagnesemia. Vitamin D deficiency was id...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-010-0117-z
更新日期:2010-09-01 00:00:00
abstract:OBJECTIVE:To compare the efficacy of phenobarbitone and phenytoin for treatment of neonatal seizures in term and near-term neonates. DESIGN:Open labeled randomized controlled trial. SETTING:Neonatal intensive care unit of a level II unit from India, from November 2008 to September 2009. PARTICIPANTS:All term and lat...
journal_title:Indian pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1007/s13312-013-0218-6
更新日期:2013-08-01 00:00:00
abstract:OBJECTIVE:To assess the glycometabolic function in chronically transfused patients of beta- thalassemia major in terms of glucose tolerance, insulin secretion, insulin resistance index, and beta cell function index and to determine their relationship with clinical and biochemical profile. METHODS:30 homozygous thalass...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2006-05-01 00:00:00
abstract::There is a large child work force in India reported to be about 40 million. Child labor is being regarded as a form of modern slavery, as children are forced to work or have no choice to refuse work. Children are employed in a variety of occupations, many of which are hazardous. Exposure to machinery, pesticides, dust...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2019-08-15 00:00:00