Current spectrum of hepatobiliary disorders in northern India.

Abstract:

OBJECTIVE:To evaluate the current spectrum of hepatobiliary disorders in children in Northern India. SETTING:Tertiary level referral hospital. METHODS:All children with hepatobiliary disorders presenting between January 1992 through July 1995 were evaluated by clinical assessment, liver function tests, viral and autoimmune markers, liver biopsy, copper studies and other relevant investigations. RESULTS:Two hundred and thirty five children with hepatobiliary disorders were seen over three and a half years period (67 cases per year). Acute hepatitis (28%), chronic liver disease (36%) and neonatal cholestasis syndrome (NCS) (26%) were the most common patterns of liver diseases. Chronic liver diseases were constituted by ICC (2%), post-hepatitic etiology (13%), Wilson's disease (21%), autoimmune (4%), non-Wilsonian metabolic diseases (16%), hepatic venous outflow obstruction (2%) and non-cirrhotic portal fibrosis (1%). Cirrhosis was documented in 71% and chronic hepatitis in 12% of cases with chronic liver disease. Fulminant hepatic failure was the presentation in 4% of children with liver diseases. CONCLUSION:Chronic liver diseases in Northern India are mainly constituted by post hepatitic, metabolic and cryptogenic etiology and ICC is rarely encountered. NCS is also one of the major subgroups of liver diseases in children.

journal_name

Indian Pediatr

journal_title

Indian pediatrics

authors

Yachha SK,Sharma BC,Khanduri A,Srivastava A

subject

Has Abstract

pub_date

1997-10-01 00:00:00

pages

885-90

issue

10

eissn

0019-6061

issn

0974-7559

journal_volume

34

pub_type

杂志文章
  • Acute renal failure due to acute tubulointerstitial nephritis.

    abstract::Acute interstitial nephritis (AIN) should be ruled out in children with unexplained acute renal failure. We present a 4 1/2 year old girl who presented with oliguric acute renal failure preceded by a febrile illness. Renal histopathology revealed features of drug induced AIN. She recovered with dialysis, other support...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Premalatha R,Phadke KD,Gag I,Rout P

    更新日期:2003-04-01 00:00:00

  • Retinopathy of prematurity in a tertiary care center--incidence, risk factors and outcome.

    abstract:OBJECTIVE:To study the incidence and risk factors predisposing to retinopathy of prematurity (ROP) and to assess the outcome after laser photocoagulation. DESIGN:Prospective cohort observational study. SETTING:Infants admitted to a neonatal intensive care unit of a referral hospital between 2000-2006 and followed up ...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Chaudhari S,Patwardhan V,Vaidya U,Kadam S,Kamat A

    更新日期:2009-03-01 00:00:00

  • Optimum age of a child for BCG vaccination.

    abstract::The objectives of this study were to evaluate whether a newborn or a neonate is capable of responding immunologically after BCG vaccination and to find out if this immunity persists for one year. Normal infants aged between 0 days-3 months brought to immunization centre were included in the study. In vitro leukocyte m...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Vijayalakshmi V,Kumar S,Kiran AL,Rani HS,Murthy KJ

    更新日期:1994-12-01 00:00:00

  • Immune thrombocytopenic purpura: historical perspective, current status, recent advances and future directions.

    abstract::Immune thrombocytopenic purpura (ITP) has witnessed many changes and updates over the past decade. The definitions of disease subtypes, course and response to treatment have all been standardized recently. Consequent to the lack of an international consensus management guideline, wide variations exist in treatment pra...

    journal_title:Indian pediatrics

    pub_type: 杂志文章,评审

    doi:10.1007/s13312-012-0195-1

    authors: Anoop P

    更新日期:2012-10-01 00:00:00

  • Association between dietary habits and asthma severity in children.

    abstract:OBJECTIVE:To investigate association between dietary habits and asthma severity in children. DESIGN:Cross-sectional study. SETTING:Two teaching hospitals in Brazil. PARTICIPANTS:Cases (n=268) were children (3-12yr) with persistent asthma and age-matched controls (n=126) were those with intermittent asthma. MAIN OUT...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:10.1007/s13312-015-0561-x

    authors: Silveira DH,Zhang L,Prietsch SO,Vecchi AA,Susin LR

    更新日期:2015-01-01 00:00:00

  • Tachypnea and Other Danger Signs vs Pulse Oximetry for Prediction of Hypoxia in Severe Pneumonia/Very Severe Disease.

    abstract:OBJECTIVE:To compare the performance of respiratory rate and other clinical signs against pulse oximetry for predicting hypoxia in children with Severe pneumonia/Very severe disease as per Integrated Management of Neonatal and Childhood Illness (IMNCI) classification. DESIGN:Cross-sectional study. SETTING:Pediatric e...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:10.1007/s13312-017-1163-6

    authors: Alwadhi V,Dewan P,Malhotra RK,Shah D,Gupta P

    更新日期:2017-09-15 00:00:00

  • Factors influencing survival in esophageal atresia.

    abstract::There is little published literature from the third World countries that described the factors influencing survival of babies with esophageal atresia. We analysed 25 consecutive neonates treated for esophageal atresia. The overall survival rate was 36%. All 4 babies in Waterston Group A, 37.5% in Group B, and 15.4% in...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Krishna A,Murali MV,Ahuja S,Kaur N

    更新日期:1994-01-01 00:00:00

  • Birth asphyxia and neurodevelopmental outcome.

    abstract::Thirty six neonates with severe birth asphyxia (Apgar score less than or equal to 3 at 1 min), 32 with moderate birth asphyxia (Apgar score 4 to 6 at 1 min) and 35 controls (Apgar score greater than or equal to 7 at 1 min) matched for weight and gestation were followed up prospectively for neurodevelopmental outcome. ...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Deorari AK,Paul VK,Singh M

    更新日期:1989-08-01 00:00:00

  • Neonatal jaundice and splenic hematoma.

    abstract::In the newborn period, unconjugated hyperbilirubinemia (UHB) is common, multifactoral, and associated with a variety of physiologic and pathologic conditions. The most commonly identified pathologic cause leading to hyperbilirubinemia is hemolytic disease of the newborn. We report a five-days-old female infant with ne...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Zenciroğlu A,Tayman C,Bas AY,Demirel N

    更新日期:2006-01-01 00:00:00

  • Oral Paracetamol for Closure of Patent Ductus Arteriosus in Selected Preterm Neonates.

    abstract::We prospectively studied the effect of oral paracetamol in closing hemodynamically significant Patent ductus arteriosus in preterm infants (gestational age <32 weeks) where Ibuprofen was contraindicated. 29 of 40 neonates (72.5%) showed successful response while 11 (29.5%) failed to show any response. No major complic...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Mohanty PK,Nagesh NK,Razak A

    更新日期:2016-02-01 00:00:00

  • Biliary atresia and cytomegalovirus and response to valganciclovir.

    abstract::Biliary atresia has been commonly reported with cytomegalovirus (CMV) infection. CMV positive patients may present with a later onset however long term outcome is similar to non-CMV patients. There are very few case reports of role of antivirals in CMV and biliary atresia. We treated a 2 month old girl with biliary at...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:10.1007/s13312-012-0092-7

    authors: Shah I,Bhatnagar S

    更新日期:2012-06-01 00:00:00

  • Lung function tests in normal Indian children.

    abstract::The forced vital capacity, forced expiratory volume in one second, peak expiratory flow, mid-expiratory flow and maximum voluntary ventilation was measured in 632 healthy, normal children from Metropolitan city of Bombay using computerized spirometer. The children were between age range 6 years to 15 years and belong ...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Chowgule RV,Shetye VM,Parmar JR

    更新日期:1995-02-01 00:00:00

  • Transfusion related acute lung injury in a child with leukemia.

    abstract::Transfusion-related acute lung injury is a rare form of acute respiratory distress syndrome of possible immune etiology that develops immediately after a blood product transfusion. Clinicians need to be aware of this condition as prompt recognition and supportive management can prevent unwanted morbidity and mortality...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Radhakrishnan V,Coshic P,Bakhshi S

    更新日期:2012-02-01 00:00:00

  • Epidemiology of Ocular Trauma in a Pediatric Referral Unit at Sao Paulo, Brazil.

    abstract::We performed a retrospective study of hospital records of children younger than 14 years with ocular trauma seen at our center in Sao Paulo, Brazil, between 2011 and 2012. From the total number of cases, 224 (89.2%) could be easily avoided. Accidents occurred with 5 children under 1 year of age; with one baby as young...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Pereira RM,Paschoalato MB,Peixoto AO,Marson FAL,Fraga AMA

    更新日期:2020-12-26 00:00:00

  • Measurement of neonatal skinfold thickness--is it of any clinical relevance?

    abstract::The skinfold thickness (SFT) was measured in 750 Punjabi newborns at triceps and subscapular sites using a Harpenden's Caliper. It was correlated with various maternal and neonatal factors. SFT increased with increasing gestation but showed a decline after 40 weeks. There was a positive correlation of SFT with birth w...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Verma M,Singh D,Chhatwal J,Jayaharan S

    更新日期:1991-11-01 00:00:00

  • Integrated approach to maternal and child health and family planning.

    abstract::India has been emphasizing the interrelationship between primary health care, maternal and child health, and family planning as the major problem for family welfare. Family welfare has been adopted at the national level by the government. Integration of these 2 components of family welfare maternal and child health ...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Bhargava I

    更新日期:1983-06-01 00:00:00

  • Comparison of JSS Formula with Modified Shukla's Formula for Insertion of Umbilical Venous Catheter: A Randomized Controlled Study.

    abstract:OBJECTIVE:To compare the rate of optimal position of UVC between modified Shukla's formula and JSS formula. METHODS:Babies requiring umbilical vein catheterization were randomized to either Shukla or JSS formula group. Post-procedure X-ray was taken to check the tip position. Tip of the UVC just above the diaphragm (T...

    journal_title:Indian pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:

    authors: Krishnegowda S,Thandaveshwar D,Mahadevaswamy M,Doreswamy SM

    更新日期:2019-03-15 00:00:00

  • Potential factors related to waist circumference in urban South Indian children.

    abstract:OBJECTIVES:To identify important factors (linked to lifestyle, eating and sedentary behaviors) relating to waist circumference among urban South Indian children aged 3 to 16 years. DESIGN:Cross sectional. SETTING:Urban schools of Bangalore, from August 2008 to January 2010. PARTICIPANTS:8444 children; 4707 children ...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:10.1007/s13312-012-0027-3

    authors: Kuriyan R,Thomas T,Sumithra S,Lokesh DP,Sheth NR,Joy R,Bhat S,Kurpad AV

    更新日期:2012-02-01 00:00:00

  • Use of Learning Platforms for Quality Improvement.

    abstract::Ensuring quality in healthcare today has become extremely essential to ensure adequate utilization of healthcare services and improved outcomes. In addition to essential infrastructure in terms of safe and adequate space, knowledgeable and skilled health workers, and essential equipment and supply, the healthcare team...

    journal_title:Indian pediatrics

    pub_type: 杂志文章,评审

    doi:

    authors: Mehta R,Sharma KA

    更新日期:2018-09-15 00:00:00

  • Myocardial dysfunction due to hypocalcemia.

    abstract::Hypocalcemia is a curable cause of myocardial dysfunction and clinical congestive cardiac failure, with only stray reports available in literature. We describe 15 infants presenting with severe left ventricular dysfunction, who were found to have hypocalcemia with or without hypomagnesemia. Vitamin D deficiency was id...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:10.1007/s13312-010-0117-z

    authors: Tomar M,Radhakrishnan S,Shrivastava S

    更新日期:2010-09-01 00:00:00

  • Adiposity and Cortisol Response to Stress in Indian Adolescents.

    abstract:OBJECTIVE:We examined associations of different adiposity measures with cortisol responses during the Trier Social Stress Test for children (TSST-C). DESIGN:Descriptive study. SETTING:Holdsworth Memorial Hospital, Mysore, India. PARTICIPANTS:Adolescents aged 13.5y from a birth cohort were recruited (N=269, 133 boys)...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Krishnaveni GV,Jones A,Veena SR,Somashekara R,Karat SC,D Fall CH

    更新日期:2018-02-15 00:00:00

  • Treatment of nephrotic syndrome.

    abstract::There are well defined therapeutic protocols for childhood nephrotic syndrome. Appropriate therapy helps in minimizing side effects besides decreasing referrals to tertiary care centres. We have analysed the appropriateness of therapy of primary care physicians in 111 children with nephrotic syndrome referred to our I...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Gulati S,Kher V,Elhence R,Kumar P,Sharma RK,Gupta A

    更新日期:1994-02-01 00:00:00

  • New antifungal agents in pediatric practice.

    abstract::Clinical needs for new antifungal agents have steadily increased with the rise and alteration in spectrum of invasive mycoses in children and neonates having AIDS, malignancies and undergoing immunosuppressive therapies. Several new options are now available for management of serious fungal infections. The aim of this...

    journal_title:Indian pediatrics

    pub_type: 杂志文章,评审

    doi:

    authors: Das S,Shivaprakash MR,Chakrabarti A

    更新日期:2009-03-01 00:00:00

  • Hyperinsulinemic Hypoglycemia in Infancy: Current Concepts in Diagnosis and Management.

    abstract:PURPOSE:Molecular basis of various forms of hyperinsulinemic hypoglycemia, involving defects in key genes regulating insulin secretion, are being increasingly reported. However, the management of medically unresponsive hyperinsulinism still remains a challenge as current facilities for genetic diagnosis and appropriate...

    journal_title:Indian pediatrics

    pub_type: 杂志文章,评审

    doi:10.1007/s13312-015-0772-1

    authors: Vora S,Chandran S,Rajadurai VS,Hussain K

    更新日期:2015-12-01 00:00:00

  • Nasal foreign body presenting as unilateral headache.

    abstract::We report a 6 year old female child, who presented with history of right sided recurrent headache for four months. On diagnostic nasal endoscopy, a metallic foreign body was seen impacted between superior turbinate, middle turbinate and nasal septum which was removed using pediatric nasal endoscope. Following removal,...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Jain A,Shah M,Jain S

    更新日期:2011-08-01 00:00:00

  • Molecular Testing of MECP2 Gene in Rett Syndrome Phenotypes in Indian Girls.

    abstract:OBJECTIVE:To assess yield of MECP2 gene sequence variations analysis and large deletions in suspected cases of Rett syndrome. DESIGN:Descriptive study. SETTING:Tertiary-care medical genetics center. PATIENTS:Girls with neuroregression, postnatal microcephaly and signs and symptoms suggestive of classical and atypica...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Lallar M,Rai A,Srivastava P,Mandal K,Gupta N,Kabra M,Phadke SR

    更新日期:2018-06-15 00:00:00

  • Effect of oil massage on growth and neurobehavior in very low birth weight preterm neonates.

    abstract:OBJECTIVE:To study the effect of oil massage on growth and neurobehavior in preterm babies less than 1500 g. DESIGN:Randomized Controlled Trial. SETTING:Tertiary level neonatal unit of a teaching hospital. SUBJECTS:Neonates with birth weight <1500 grams, gestation >37 weeks, receiving enteral feeds of at least 100 m...

    journal_title:Indian pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:

    authors: Arora J,Kumar A,Ramji S

    更新日期:2005-11-01 00:00:00

  • A study of twin births in rural communities of Gujarat.

    abstract::The incidence and the factors that influence twinning were studied in six villages of Dholka Taluka, a rural field training centre. The twinning rate was 10.10 per 1000 maternities. The monozygotic and dizygotic twinning rates were 4.53 and 5.56, respectively by applying Weinberg's differential formula. In three fourt...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Talsania NJ,Purohit CK

    更新日期:1990-03-01 00:00:00

  • Pneumococcal hemolytic uremic syndrome.

    abstract::We report Hemolytic Uremic Syndrome (HUS) induced by Streptococcus pneumoniae in a 20 month-old girl. She responded well to hemodialysis. ...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Gite A,Bhide S

    更新日期:2007-05-01 00:00:00

  • Hematopoietic stem cell transplantation in children with genetic defects.

    abstract::Seventeen children (mean age: 7.2 years) with genetic defects involving hematopoietic cell production or function, underwent 19 allogeneic stem cell transplantations from HLA identical siblings. Twelve children were suffering from thalassemia major; 2 from Diamond Blackfan anemia; 2 from Fanconi anemia and 1 from cong...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Nair V,Das S,Sharma A

    更新日期:2009-03-01 00:00:00