Abstract:
OBJECTIVE:To evaluate adiponectin levels in children and adolescents with type I diabetes, and their relationship to long term complications. DESIGN:Cross sectional. SETTING:Tertiary referral hospital, Cairo, Egypt. PARTICIPANTS:Thirty children and adolescents with type I diabetes mellitus, classified into complicated and non-complicated and compared to 10 healthy age and sex matched subjects as a control group. METHODS:All children underwent anthropometric measurements, neurological assessment, fundus examination, echocardiography and assays of HbA1c, creatinine, 24-hr urinary protein, and serum adiponectin. MAIN OUTCOME MEASURE:Relationship of serum adiponectin to complications of type I diabetes mellitus, and glucose control. RESULTS:Serum adiponectin was significantly elevated in complicated diabetes (10.3 ± 5.9 pg/dL) as compared to the controls (6.5 ± 3.7 pg/dL) (P<0.01), and correlated directly with HbA1c (P<0.05) and creatinine (P<0.001). Patients with nephropathy showed high values of adiponectin (15.7 ± 3.7 pg/dL). CONCLUSION:Elevated adiponectin level in children and adolescents with type I diabetes indicates poor glycemic control and development of complications, especially nephropathy.
journal_name
Indian Pediatrjournal_title
Indian pediatricsauthors
Habeeb NM,Youssef OI,Saab AA,El Hadidi ESdoi
10.1007/s13312-012-0041-5subject
Has Abstractpub_date
2012-04-01 00:00:00pages
277-80issue
4eissn
0019-6061issn
0974-7559pii
S09747559INPE1000420-1journal_volume
49pub_type
杂志文章abstract::We report a case of primary hyperparathyroidism associated with prolonged hungry syndrome (HBS) after parathyroid adenomectomy in a 10-year-old girl. Bone mineral density (BMD) revealed severe loss of cancellous BMD. Overt bone disease, high alkaline phosphatase, decreased cancellous BMD and a large adenoma can be use...
journal_title:Indian pediatrics
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更新日期:2009-02-01 00:00:00
abstract:OBJECTIVE:To study the clinical profile and outcome of langerhans cell histiocytosis in children upto 2 years of life. DESIGN:Retrospective analysis. METHODS:Medical records of Children upto 2 years of age with a diagnosis of langerhans cell histiocytosis (LCH) were analyzed. Their clinical pattern, treatment modalit...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract::Participation in research is important in producing doctors with an understanding of evidence-based medicine. Though a mandatory part in post-graduate medical course, research has largely been invisible from the under graduation medical course in India. Very few research opportunities are available at under graduate l...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-017-1104-4
更新日期:2017-05-15 00:00:00
abstract::Fifty eight (16%) of the 362 patients, who reported to Dermatology and STD Department with symptoms pertaining to their genitourinary system were below 14 years of age. Fifty four (93.1%) of these children belonged to families of lower socio-economic strata. All the children were slum dwellers and none of them had stu...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract::The discussion section explains the meaning of results to the readers, and addresses the implications of the findings emanating from the particular study. Authors should compare their results with previous reports, and attempt to explain similarities and differences. It is useful to outline the limitations and strengt...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-016-0955-4
更新日期:2016-10-08 00:00:00
abstract::Hypocalcemia is a curable cause of myocardial dysfunction and clinical congestive cardiac failure, with only stray reports available in literature. We describe 15 infants presenting with severe left ventricular dysfunction, who were found to have hypocalcemia with or without hypomagnesemia. Vitamin D deficiency was id...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-010-0117-z
更新日期:2010-09-01 00:00:00
abstract::Transfusion-related acute lung injury is a rare form of acute respiratory distress syndrome of possible immune etiology that develops immediately after a blood product transfusion. Clinicians need to be aware of this condition as prompt recognition and supportive management can prevent unwanted morbidity and mortality...
journal_title:Indian pediatrics
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doi:
更新日期:2012-02-01 00:00:00
abstract::We enrolled 75 consecutive infants presenting with history of first seizure at a tertiary care hospital in New Delhi, India. Clinical and biochemical work-up for etiology, and electroencephalography were performed in all infants. Developmental assessment was done 3-month after discharge. 72% had generalized seizures, ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2016-10-08 00:00:00
abstract:OBJECTIVE:To study the effect of zinc supplementation in children under 5 years of age rom low- and middle-income countries (LMICs) on anthropometry and prevalence of malnutrition. Design:Systematic review of randomized controlled trials and cluster randomized trials. SETTING:Low- and middle-income countries. PARTIC...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2019-05-15 00:00:00
abstract::The incidence and the factors that influence twinning were studied in six villages of Dholka Taluka, a rural field training centre. The twinning rate was 10.10 per 1000 maternities. The monozygotic and dizygotic twinning rates were 4.53 and 5.56, respectively by applying Weinberg's differential formula. In three fourt...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
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journal_title:Indian pediatrics
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doi:
更新日期:1993-02-01 00:00:00
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journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2020-03-15 00:00:00
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journal_title:Indian pediatrics
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doi:
更新日期:2020-11-15 00:00:00
abstract:OBJECTIVE:To observe the safety and efficacy of Colistimethate sodium in children infected with gram-negative bacteria, susceptible only to colistimethate sodium. METHODS:This prospective observational study done over 2 years observed children who received colistin for >48 h, for renal failure as defined by p-RIFLE cr...
journal_title:Indian pediatrics
pub_type: 杂志文章
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更新日期:2015-02-01 00:00:00
abstract:OBJECTIVE:To document effects of intrapartum risk factors for early onset sepsis (EOS) on CRP levels in neonates and to assess the suitability of this test in diagnosing EOS. DESIGN:Cohort study. SETTING:Labour and post natal wards in a tertiary level teaching hospital in India. SUBJECTS:250 neonates at risk of deve...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2004-09-01 00:00:00
abstract::Hepatic abscess in a neonate is a rare but serious disorder. Diagnosis of hepatic abscess requires a high index of suspicion in any septic neonate. CT scan and ultrasound of liver are the most sensitive diagnostic tests in detection of hepatic abscess. Portal vein thrombosis and portal cavernoma formation is hitherto ...
journal_title:Indian pediatrics
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journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2018-10-15 00:00:00
abstract:OBJECTIVE:To compare the effect of withholding maintenance phenobarbitone on breakthrough seizures. DESIGN:A double blind randomized controlled trial. SETTING:Level II neonatal intensive care unit (NICU) of a teaching hospital in Northern India. PARTICIPANTS:152 term and near term neonates (34 weeks of gestation age...
journal_title:Indian pediatrics
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2016-12-15 00:00:00
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journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1994-11-01 00:00:00
abstract::Transfusion-associated graft-versus-host disease (TA-GVHD) is a dreaded complication in immunocompromized hosts. The diagnosis is often delayed because of lack of awareness and the non-specific clinical features. More than 90% patients succumb to refractory infections. The only effective preventive measure is administ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2004-12-01 00:00:00
abstract::In the present study, brainstorm auditory evoked responses (BAER) were recorded in 68 at risk neonates discharged from the neonatal ICU of Safdarjung Hospital. The high risk group of 35 neonates included 13 neonates with multiple (3-4) risk factors and 22 neonates with single risk factors, viz., prematurity (less than...
journal_title:Indian pediatrics
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doi:
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journal_title:Indian pediatrics
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journal_title:Indian pediatrics
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doi:
更新日期:2008-12-01 00:00:00
abstract::No clear operational definition of 'Community Participation' has emerged over the last decade of experimentation. One reason is the markedly contrasting perspectives that exist at different levels such as Aid Agencies, Ministry of Health, Government Health Programmes and Non-Government Organizations (NGOs). A more pra...
journal_title:Indian pediatrics
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doi:
更新日期:1989-11-01 00:00:00
abstract::Beta thalassemia is a common genetic disorder in Indians. Around 10,000 thala-ssemia major cases are born every year. The treatment of thalassemia major patients imposes a financial burden on the family. Much progress has been made in last 15 years in understanding of the pathogenesis of thalassemia and development of...
journal_title:Indian pediatrics
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doi:
更新日期:2006-06-01 00:00:00
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journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2003-12-01 00:00:00
abstract::The retrospective study was carried out to examine performance of Pottels height- independent equation compared to Schwartzs height-dependent equation to estimate glomerular filtration rate in 115 children in Indian setting. The Pottels equation performed well compared to updated Schwartz equation (R2=0.94, mean bias ...
journal_title:Indian pediatrics
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更新日期:2017-01-15 00:00:00
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journal_title:Indian pediatrics
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2009-10-01 00:00:00
abstract::Informed consent is a communication process of providing the patient/parents/guardians with relevant information regarding the treatment and the diagnosis, so that they can make informed decisions. The process of informed consent in pediatric patients is not well understood. The amount of information to be disclosed i...
journal_title:Indian pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s13312-010-0173-4
更新日期:2010-12-01 00:00:00
abstract::One hundred and four cases of osteoarticular tuberculosis were studied. There were 74 boys (71.2%) and 30 girls (28.8%). The mean age at the onset of symptoms was 7.3 years, ranging from 9 months to 18 years. Seventy four cases (71%) reported 3 months after onset of symptoms. The spine was the commonest site involved ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1992-09-01 00:00:00