Adiponectin as a marker of complications in type I diabetes.

Abstract:

OBJECTIVE:To evaluate adiponectin levels in children and adolescents with type I diabetes, and their relationship to long term complications. DESIGN:Cross sectional. SETTING:Tertiary referral hospital, Cairo, Egypt. PARTICIPANTS:Thirty children and adolescents with type I diabetes mellitus, classified into complicated and non-complicated and compared to 10 healthy age and sex matched subjects as a control group. METHODS:All children underwent anthropometric measurements, neurological assessment, fundus examination, echocardiography and assays of HbA1c, creatinine, 24-hr urinary protein, and serum adiponectin. MAIN OUTCOME MEASURE:Relationship of serum adiponectin to complications of type I diabetes mellitus, and glucose control. RESULTS:Serum adiponectin was significantly elevated in complicated diabetes (10.3 ± 5.9 pg/dL) as compared to the controls (6.5 ± 3.7 pg/dL) (P<0.01), and correlated directly with HbA1c (P<0.05) and creatinine (P<0.001). Patients with nephropathy showed high values of adiponectin (15.7 ± 3.7 pg/dL). CONCLUSION:Elevated adiponectin level in children and adolescents with type I diabetes indicates poor glycemic control and development of complications, especially nephropathy.

journal_name

Indian Pediatr

journal_title

Indian pediatrics

authors

Habeeb NM,Youssef OI,Saab AA,El Hadidi ES

doi

10.1007/s13312-012-0041-5

subject

Has Abstract

pub_date

2012-04-01 00:00:00

pages

277-80

issue

4

eissn

0019-6061

issn

0974-7559

pii

S09747559INPE1000420-1

journal_volume

49

pub_type

杂志文章
  • Prolonged hungry bone syndrome in a 10-year-old child with parathyroid adenoma.

    abstract::We report a case of primary hyperparathyroidism associated with prolonged hungry syndrome (HBS) after parathyroid adenomectomy in a 10-year-old girl. Bone mineral density (BMD) revealed severe loss of cancellous BMD. Overt bone disease, high alkaline phosphatase, decreased cancellous BMD and a large adenoma can be use...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Simsek E,Arikan Y,Dallar Y,Akkus MA

    更新日期:2009-02-01 00:00:00

  • Langerhans cell histiocytosis in children less than 2 years of age.

    abstract:OBJECTIVE:To study the clinical profile and outcome of langerhans cell histiocytosis in children upto 2 years of life. DESIGN:Retrospective analysis. METHODS:Medical records of Children upto 2 years of age with a diagnosis of langerhans cell histiocytosis (LCH) were analyzed. Their clinical pattern, treatment modalit...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Kusuma Kumary P,Priyakumari T,Chellam VG,James FV,Nair MK

    更新日期:1999-01-01 00:00:00

  • Lack of Research Amongst Undergraduate Medical Students in India: It's time to Act and Act Now.

    abstract::Participation in research is important in producing doctors with an understanding of evidence-based medicine. Though a mandatory part in post-graduate medical course, research has largely been invisible from the under graduation medical course in India. Very few research opportunities are available at under graduate l...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:10.1007/s13312-017-1104-4

    authors: Garg R,Goyal S,Singh K

    更新日期:2017-05-15 00:00:00

  • Sexually transmitted diseases in children.

    abstract::Fifty eight (16%) of the 362 patients, who reported to Dermatology and STD Department with symptoms pertaining to their genitourinary system were below 14 years of age. Fifty four (93.1%) of these children belonged to families of lower socio-economic strata. All the children were slum dwellers and none of them had stu...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Pandhi RK,Khanna N,Sekhri R

    更新日期:1995-01-01 00:00:00

  • Discussion: The Heart of the Paper.

    abstract::The discussion section explains the meaning of results to the readers, and addresses the implications of the findings emanating from the particular study. Authors should compare their results with previous reports, and attempt to explain similarities and differences. It is useful to outline the limitations and strengt...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:10.1007/s13312-016-0955-4

    authors: Bagga A

    更新日期:2016-10-08 00:00:00

  • Myocardial dysfunction due to hypocalcemia.

    abstract::Hypocalcemia is a curable cause of myocardial dysfunction and clinical congestive cardiac failure, with only stray reports available in literature. We describe 15 infants presenting with severe left ventricular dysfunction, who were found to have hypocalcemia with or without hypomagnesemia. Vitamin D deficiency was id...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:10.1007/s13312-010-0117-z

    authors: Tomar M,Radhakrishnan S,Shrivastava S

    更新日期:2010-09-01 00:00:00

  • Transfusion related acute lung injury in a child with leukemia.

    abstract::Transfusion-related acute lung injury is a rare form of acute respiratory distress syndrome of possible immune etiology that develops immediately after a blood product transfusion. Clinicians need to be aware of this condition as prompt recognition and supportive management can prevent unwanted morbidity and mortality...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Radhakrishnan V,Coshic P,Bakhshi S

    更新日期:2012-02-01 00:00:00

  • Etiology and Short-term Outcome of First Seizure in Hospitalized Infants.

    abstract::We enrolled 75 consecutive infants presenting with history of first seizure at a tertiary care hospital in New Delhi, India. Clinical and biochemical work-up for etiology, and electroencephalography were performed in all infants. Developmental assessment was done 3-month after discharge. 72% had generalized seizures, ...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Nikunj NK,Mishra D,Juneja M,Talukdar B

    更新日期:2016-10-08 00:00:00

  • Zinc Supplementation for Promoting Growth in Children Under 5 years of age in Low- and Middle-income Countries: A Systematic Review.

    abstract:OBJECTIVE:To study the effect of zinc supplementation in children under 5 years of age rom low- and middle-income countries (LMICs) on anthropometry and prevalence of malnutrition. Design:Systematic review of randomized controlled trials and cluster randomized trials. SETTING:Low- and middle-income countries. PARTIC...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Gera T,Shah D,Sachdev HS

    更新日期:2019-05-15 00:00:00

  • A study of twin births in rural communities of Gujarat.

    abstract::The incidence and the factors that influence twinning were studied in six villages of Dholka Taluka, a rural field training centre. The twinning rate was 10.10 per 1000 maternities. The monozygotic and dizygotic twinning rates were 4.53 and 5.56, respectively by applying Weinberg's differential formula. In three fourt...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Talsania NJ,Purohit CK

    更新日期:1990-03-01 00:00:00

  • Prospective study of nosocomial enteric infections in a pediatric hospital, Calcutta.

    abstract::Hospital acquired enteric infections were investigated by studying 3138 children under 5 years of age who were admitted without diarrhea in nine medical words of a pediatric hospital, Calcutta during the period between March and September 1987. Three hundred and twenty (10.2%) children developed nosocomial diarrhea du...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Dutta P,Mitra U,Rasaily R,Bhattacharya SK,De SP,Sen D,Saha MR,Nair GB,Niyogi SK,Das P

    更新日期:1993-02-01 00:00:00

  • Efficacy, Tolerability and Serum Phenytoin Levels after Intravenous Fosphenytoin Loading Dose in Children with Status Epilepticus.

    abstract:OBJECTIVE:To evaluate the efficacy and tolerability of intravenous fosphenytoin in children with status epilepticus, and resulting serum total phenytoin levels. METHODS:In this prospective study, 51 children aged less than 18 years received intravenous loading dose of fosphenytoin (18-20 mg/kg). Serum total phenytoin ...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Srivastava K,Bhartiya S,Gavli V,Patil R,Rajadhyaksha S

    更新日期:2020-03-15 00:00:00

  • Epidemiological and Clinical Profile of Pediatric Inflammatory Multisystem Syndrome - Temporally Associated with SARS-CoV-2 (PIMS-TS) in Indian Children.

    abstract:Background:We describe the demographic, clinical and labo-ratory findings along with the treatment and outcomes among children meeting the case definition of Pediatric Inflammatory Multisystem Syndrome - Temporally associated with SARS-CoV-2 (PIMS-TS). METHODS:We analyzed the clinical and laboratory findings of childr...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Dhanalakshmi K,Venkataraman A,Balasubramanian S,Madhusudan M,Amperayani S,Putilibai S,Sadasivam K,Ramachandran B,Ramanan AV

    更新日期:2020-11-15 00:00:00

  • Safety and efficacy of intravenous colistin in children.

    abstract:OBJECTIVE:To observe the safety and efficacy of Colistimethate sodium in children infected with gram-negative bacteria, susceptible only to colistimethate sodium. METHODS:This prospective observational study done over 2 years observed children who received colistin for >48 h, for renal failure as defined by p-RIFLE cr...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:10.1007/s13312-015-0586-1

    authors: Kumar PP,Giri SR,Shaikh FA,Panigrahy N,Chirla D

    更新日期:2015-02-01 00:00:00

  • Is C-reactive protein level useful in differentiating infected from uninfected neonates among those at risk of infection?

    abstract:OBJECTIVE:To document effects of intrapartum risk factors for early onset sepsis (EOS) on CRP levels in neonates and to assess the suitability of this test in diagnosing EOS. DESIGN:Cohort study. SETTING:Labour and post natal wards in a tertiary level teaching hospital in India. SUBJECTS:250 neonates at risk of deve...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Mathai E,Christopher U,Mathai M,Jana AK,Rose D,Bergstrom S

    更新日期:2004-09-01 00:00:00

  • Portal vein thrombosis complicating neonatal hepatic abscess.

    abstract::Hepatic abscess in a neonate is a rare but serious disorder. Diagnosis of hepatic abscess requires a high index of suspicion in any septic neonate. CT scan and ultrasound of liver are the most sensitive diagnostic tests in detection of hepatic abscess. Portal vein thrombosis and portal cavernoma formation is hitherto ...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Aggarwal S,Mathur NB,Garg A

    更新日期:2003-10-01 00:00:00

  • Milky Mesentery: Acute Abdomen with Chylous Ascites.

    abstract:BACKGROUND:Clinical presentations of intestinal lymphangiectasia include pitting edema, chylous ascites, pleural effusion, diarrhea, malabsorption and intestinal obstruction. CASE CHARACTERISTICS:An 8-year-old male child presented to the emergency department with clinical features of peritonitis, raising suspicion of ...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Goel A,Gaur MK,Garg PK

    更新日期:2018-10-15 00:00:00

  • Effect of Withholding Phenobarbitone Maintenance in Neonatal Seizures: A Randomized Controlled Trial.

    abstract:OBJECTIVE:To compare the effect of withholding maintenance phenobarbitone on breakthrough seizures. DESIGN:A double blind randomized controlled trial. SETTING:Level II neonatal intensive care unit (NICU) of a teaching hospital in Northern India. PARTICIPANTS:152 term and near term neonates (34 weeks of gestation age...

    journal_title:Indian pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:

    authors: Saxena P,Singh A,Upadhyay A,Gupta P,Sharma S,Vishnubatla S

    更新日期:2016-12-15 00:00:00

  • Cranial ultrasonic assessment of infants with acute bacterial meningitis.

    abstract::A prospective study was performed on 44 patients (newborn to one year old) with acute bacterial meningitis. Sonograms were obtained within 72 hours of diagnosis, and repeated on 7th, 14th or at an early date, if required. The spectrum of sonographic features of meningitis included normal scan (35.4%), echogenic sulci ...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Soni JP,Gupta BD,Soni M,Gupta M,Dabi DR,Nemal KR

    更新日期:1994-11-01 00:00:00

  • Transfusion associated graft versus host disease.

    abstract::Transfusion-associated graft-versus-host disease (TA-GVHD) is a dreaded complication in immunocompromized hosts. The diagnosis is often delayed because of lack of awareness and the non-specific clinical features. More than 90% patients succumb to refractory infections. The only effective preventive measure is administ...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Gupta A,Bansal D,Dass R,Das A

    更新日期:2004-12-01 00:00:00

  • Hearing assessment by brainstem auditory evoked responses (BAER) in neonates at risk.

    abstract::In the present study, brainstorm auditory evoked responses (BAER) were recorded in 68 at risk neonates discharged from the neonatal ICU of Safdarjung Hospital. The high risk group of 35 neonates included 13 neonates with multiple (3-4) risk factors and 22 neonates with single risk factors, viz., prematurity (less than...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Raj H,Gupta AK,Anand NK

    更新日期:1991-10-01 00:00:00

  • Thoracoscopic Retrieval of Unusual Iatrogenic Foreign Bodies.

    abstract:BACKGROUND:Management of pyothorax and pneumothorax requires aspiration and/or intercostal drainage. CASE CHARACTERISTICS:We present two cases which were complicated by instrument-related events resulting in breakage of needle or intercostal drainage tube resulting in pleural foreign body. INTERVENTION/OUTCOME:The pa...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:10.1007/s13312-016-0848-6

    authors: Manchanda V,Sengar M,Mohta A

    更新日期:2016-04-01 00:00:00

  • Acute disseminated encephalomyelitis presenting as acute psychotic disorder.

    abstract::A 5 year old boy and a 10 year old girl presented with acute onset of psychotic disorder, which occurred one week after an upper respiratory infection. MRI images of brain were consistent with the diagnosis of acute disseminated encephalomyelitis (ADEM) in both cases. ADEM is one of the differential diagnoses to be co...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Krishnakumar P,Jayakrishnan MP,Beegum MN,Riyaz A

    更新日期:2008-12-01 00:00:00

  • Community participation in health programmes.

    abstract::No clear operational definition of 'Community Participation' has emerged over the last decade of experimentation. One reason is the markedly contrasting perspectives that exist at different levels such as Aid Agencies, Ministry of Health, Government Health Programmes and Non-Government Organizations (NGOs). A more pra...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Dyal Chand A

    更新日期:1989-11-01 00:00:00

  • Common queries in thalassemia care.

    abstract::Beta thalassemia is a common genetic disorder in Indians. Around 10,000 thala-ssemia major cases are born every year. The treatment of thalassemia major patients imposes a financial burden on the family. Much progress has been made in last 15 years in understanding of the pathogenesis of thalassemia and development of...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Panigrahi I,Marwaha RK

    更新日期:2006-06-01 00:00:00

  • Efficacy of twice weekly iron supplementation in anemic adolescent girls.

    abstract::Two hundred and forty four girls with different hemoglobin levels were selected, of which forty-one were non-anemic. The rest were graded as mildly, moderately or severely anemic and supplemented with 60 mg of iron daily or twice weekly for twelve weeks. There was no significant difference in the increase in hemoglobi...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Shobha S,Sharada D

    更新日期:2003-12-01 00:00:00

  • Pottels Equation for Estimation of Glomerular Filtration Rate.

    abstract::The retrospective study was carried out to examine performance of Pottels height- independent equation compared to Schwartzs height-dependent equation to estimate glomerular filtration rate in 115 children in Indian setting. The Pottels equation performed well compared to updated Schwartz equation (R2=0.94, mean bias ...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:10.1007/s13312-017-1001-x

    authors: Barman H,Bisai S,Das BK,Nath CK,Duwarah SG

    更新日期:2017-01-15 00:00:00

  • Ferrous sulfate versus iron polymaltose complex for treatment of iron deficiency anemia in children.

    abstract::We assessed the clinical response and side effects of Ferrous sulfate (FS) and Iron polymaltose complex (IPC) in 118 children with Iron deficiency anemia (IDA). Subjects were randomized to receive therapy with either oral IPC (Group A, n=59) or oral FS (Group B, n=59); all were given elemental iron in three divided do...

    journal_title:Indian pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:

    authors: Bopche AV,Dwivedi R,Mishra R,Patel GS

    更新日期:2009-10-01 00:00:00

  • Informed consent in pediatric practice.

    abstract::Informed consent is a communication process of providing the patient/parents/guardians with relevant information regarding the treatment and the diagnosis, so that they can make informed decisions. The process of informed consent in pediatric patients is not well understood. The amount of information to be disclosed i...

    journal_title:Indian pediatrics

    pub_type: 杂志文章,评审

    doi:10.1007/s13312-010-0173-4

    authors: Kaushik JS,Narang M,Agarwal N

    更新日期:2010-12-01 00:00:00

  • Osteoarticular tuberculosis in children.

    abstract::One hundred and four cases of osteoarticular tuberculosis were studied. There were 74 boys (71.2%) and 30 girls (28.8%). The mean age at the onset of symptoms was 7.3 years, ranging from 9 months to 18 years. Seventy four cases (71%) reported 3 months after onset of symptoms. The spine was the commonest site involved ...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Singh SB,Saraf SK,Singh LI,Srivastava TP

    更新日期:1992-09-01 00:00:00