Abstract:
OBJECTIVE:To document effects of intrapartum risk factors for early onset sepsis (EOS) on CRP levels in neonates and to assess the suitability of this test in diagnosing EOS. DESIGN:Cohort study. SETTING:Labour and post natal wards in a tertiary level teaching hospital in India. SUBJECTS:250 neonates at risk of developing infection. METHODS:CRP levels in cord blood and neonatal blood at 24 hrs were estimated using commercial kits. Babies were observed for signs of sepsis for at least 48 hours. RESULTS:Seven (2.8 Percent) neonates had elevated CRP levels in the cord blood. At 24 hours, 102 (40.8 Percent) babies had elevated levels. Elevated cord CRP levels was significantly associated with rupture of membranes for 24 hours (p =0.04), labour more than 12 hours (p = 0.002), and maternal fever (p = 0.01). At 24 hours, elevated CRP levels were associated with primiparity (p= 0.006), more than three vaginal examinations after membrane rupture (p=0.02), meconium staining of amniotic fluid (p =0.02) and amnioinfusion (p =0.02). Ten (4 Percent) babies developed EOS. The negative predictive value for elevated CRP levels at 24 h was 99 Percent. CONCLUSION:Several intrapartum risk factors for EOS can cause elevation in CRP levels. However, this test may be useful in excluding infection.
journal_name
Indian Pediatrjournal_title
Indian pediatricsauthors
Mathai E,Christopher U,Mathai M,Jana AK,Rose D,Bergstrom Skeywords:
subject
Has Abstractpub_date
2004-09-01 00:00:00pages
895-900issue
9eissn
0019-6061issn
0974-7559journal_volume
41pub_type
杂志文章abstract::Transfusion-related acute lung injury is a rare form of acute respiratory distress syndrome of possible immune etiology that develops immediately after a blood product transfusion. Clinicians need to be aware of this condition as prompt recognition and supportive management can prevent unwanted morbidity and mortality...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2012-02-01 00:00:00
abstract:OBJECTIVE:To find out the degree of current undernutrition in rural reproductive age women. SETTING:49 villages of two adjoining rural blocks of Varanasi. METHODS:6130 non-pregnant and non-lactating rural women in the age group 18-45 year were studied for sociodemographic characteristics and anthropometry, i.e., weig...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1998-10-01 00:00:00
abstract::A 12-year-old male child reported with history of fever for last seven years. Hepatosplenomegaly, hepatic and bone marrow granulomas were the main features. Idiopathic Granulomatous Hepatitis (IGH), a rare syndrome amenable to immunosuppressive therapy was diagnosed. ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2004-06-01 00:00:00
abstract:OBJECTIVE:To compare the impact of postnatal lactational counseling on the weight gain and frequency of mixed feeding in full term neonates. DESIGN:Observational study. SETTING:Mother-infant pairs were observed in the maternity section of a multispecialty general hospital in Mumbai during two time periods. PARTICIPA...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-015-0678-y
更新日期:2015-07-01 00:00:00
abstract:OBJECTIVE:To study the relationship of CSF IL-1 beta and TNF-alpha with free radicals in acute bacterial meningitis (ABM) and to evaluate the clinical outcome in relation to the levels of these cytokines and free radicals in CSF. DESIGN:Prospective with controls. SETTING:Referral unit of a teaching hospital. METHODS...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2000-06-01 00:00:00
abstract::The study was undertaken to compare the antibody response of 6-12 weeks old infants after three doses of standard trivalent oral polio vaccine (TOPV) (Groups A; (n = 42) with three doses of double the amount of TOPV (Group B; n = 35). Seroconversions in Group A were 64.2, 80.9% and 57.1% for Types I, II and III poliov...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1991-10-01 00:00:00
abstract::This report is based on observations during the conduct of a study of hypocalcemia in infants and children. In a study of 50 cases, 13 exclusively breast fed infants manifesting with hypocalcemic seizures were confirmed to have vitamin D deficiency. None of the 13 infants had received vitamin D supplementation. All of...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2006-03-01 00:00:00
abstract:BACKGROUND:Clinical presentations of intestinal lymphangiectasia include pitting edema, chylous ascites, pleural effusion, diarrhea, malabsorption and intestinal obstruction. CASE CHARACTERISTICS:An 8-year-old male child presented to the emergency department with clinical features of peritonitis, raising suspicion of ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2018-10-15 00:00:00
abstract:OBJECTIVE:To determine the health-related quality of life in children with cerebral palsy and their families. METHODS:One hundred children (3-10 years of age) receiving regular rehabilitation therapy for cerebral palsy for last 1 year at a Child Development Centrer were enrolled and the Lifestyle assessment questionna...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-014-0414-z
更新日期:2014-05-01 00:00:00
abstract::Thirty-two infants above one month of age admitted to a tertiary care hospital with signs of infection and presumptive diagnosis of sepsis were included. Cytokine levels of tumor necrosis factor alpha (TNFmu) and interleukin-6 (IL 6) were estimated at admission and after 48 to 72 hr, and their relationship examined to...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2005-10-01 00:00:00
abstract::Intravenously administered rehydration therapy was compared with orally administered rehydration therapy for treating children with diarrhea in a clinical study of 3000 children admitted to the Medical College Hospital, Kottayam, India. Oral rehydration was more effective and safer than intravenously administered flu...
journal_title:Indian pediatrics
pub_type: 临床试验,杂志文章
doi:
更新日期:1978-10-01 00:00:00
abstract::In the present study, brainstorm auditory evoked responses (BAER) were recorded in 68 at risk neonates discharged from the neonatal ICU of Safdarjung Hospital. The high risk group of 35 neonates included 13 neonates with multiple (3-4) risk factors and 22 neonates with single risk factors, viz., prematurity (less than...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1991-10-01 00:00:00
abstract::We report on the etiology and the short term outcome (3 month) of children with acute renal failure (ARF) at a tertiary care centre in north India. Acute tubular necrosis was the commonest cause of ARF (33%) especially in children <5 years of age; while in children >10 years, glomerulonephritis was the commonest cause...
journal_title:Indian pediatrics
pub_type: 信件
doi:
更新日期:2011-06-01 00:00:00
abstract::To identify an inexpensive, reliable predictor of low birth weight capable of being utilized by untrained personnel, anthropometric measures were performed on 1600 newborns in Kanpur, India. This analysis indicated that, for a birth weight of 2500 g, the critical limit of calf circumference was 10.8 cm or less. Crit...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1996-02-01 00:00:00
abstract:OBJECTIVE:To evaluate endothelial function and arterial mechanics in apparently healthy overweight adolescents. DESIGN:Analytical observational study. SETTING:Tertiary hospital. METHODS:40 asymptomatic, normotensive and non-smoking adolescents (11 to 18 years old) were evaluated. Of these 20 were overweight or obese...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2004-11-01 00:00:00
abstract:OBJECTIVE:To evaluate the efficacy and tolerability of intravenous fosphenytoin in children with status epilepticus, and resulting serum total phenytoin levels. METHODS:In this prospective study, 51 children aged less than 18 years received intravenous loading dose of fosphenytoin (18-20 mg/kg). Serum total phenytoin ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2020-03-15 00:00:00
abstract::Decline in malnutrition levels has been dismal since the 1990s. We ascertained decadal trend in childhood nutritional status between 1997 and 2007 in Chandigarh, India and assessed impact of Integrated Child Development Services (ICDS) on childhood undernutrition. A total of 803 under-five children, 547 children betwe...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-011-0058-1
更新日期:2011-04-01 00:00:00
abstract::Delayed diagnosis of undescended testes is a major problem. A retrospective review of 298 testes units was performed to assess the age at referral, age at operation, complications and final outcome. The mean age at referral was 57 months. Only 24% of cases were operated below 2 years. A similar pattern of delayed orch...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2008-06-01 00:00:00
abstract::Primary immunodeficiency disorders (PIDs) are a heterogeneous group of inherited disorders that affect different components of the immune system. There are more than 150 different disorders which have been described till date. Despite major advances in the molecular characterization of PIDs over the last 20 years, man...
journal_title:Indian pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s13312-013-0171-4
更新日期:2013-06-08 00:00:00
abstract:OBJECTIVE:To analyze variation in rotavirus-positivity using simple alternative statistical measures. METHODS:Hospital-based rotavirus surveillance among children admitted with acute gastroenteritis between 2005 and 2009. Prevalence, adjusted proportions and symmetrized index were calculated. RESULTS:Rotavirus preval...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-016-0898-9
更新日期:2016-07-08 00:00:00
abstract::Audit in medicine is a well tried means of assessing the quality of practice by using acceptable measures of outcome. Audit in maternal and child health has been limited to fatal outcomes such as maternal and perinatal deaths. The outcome of audit is of interest to the providers, the health authorities and the consume...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1994-11-01 00:00:00
abstract:OBJECTIVE:To investigate association between dietary habits and asthma severity in children. DESIGN:Cross-sectional study. SETTING:Two teaching hospitals in Brazil. PARTICIPANTS:Cases (n=268) were children (3-12yr) with persistent asthma and age-matched controls (n=126) were those with intermittent asthma. MAIN OUT...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-015-0561-x
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVE:To study the effect of zinc supplementation in children under 5 years of age rom low- and middle-income countries (LMICs) on anthropometry and prevalence of malnutrition. Design:Systematic review of randomized controlled trials and cluster randomized trials. SETTING:Low- and middle-income countries. PARTIC...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2019-05-15 00:00:00
abstract::Hospital acquired enteric infections were investigated by studying 3138 children under 5 years of age who were admitted without diarrhea in nine medical words of a pediatric hospital, Calcutta during the period between March and September 1987. Three hundred and twenty (10.2%) children developed nosocomial diarrhea du...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1993-02-01 00:00:00
abstract::Pathologic fractures in children may be due to various causes. Rarely, it may be the presenting symptom of neurofibromatosis. A misdiagnosis of Rickets and Vitamin D supplementation in such a case may wreak havoc in the form of iatrogenic hypervitaminosis D. We report one such case. ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-010-0137-8
更新日期:2010-10-01 00:00:00
abstract::In this cohort study, neurodevelopmental outcome of 20 of 24 surviving very low birth weight infants with sepsis followed up between 2008 and 2009 was compared with 20 control (uninfected infants). We found that plasma interleukin 6 and C reactive protein values were negatively correlated with mental developmental ind...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-013-0091-3
更新日期:2013-03-01 00:00:00
abstract::The forced vital capacity, forced expiratory volume in one second, peak expiratory flow, mid-expiratory flow and maximum voluntary ventilation was measured in 632 healthy, normal children from Metropolitan city of Bombay using computerized spirometer. The children were between age range 6 years to 15 years and belong ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1995-02-01 00:00:00
abstract:OBJECTIVE:To compare the efficacy of artemether and quinine in the treatment of severe malaria in hospitalized children. STUDY DESIGN:Open randomized trial. SETTING:Pediatric ward of a tertiary care center. METHODS:All children admitted with clinical manifestations of severe malaria (as per WHO criteria) and asexual...
journal_title:Indian pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2003-10-01 00:00:00
abstract:OBJECTIVES:To generate evidence on the current situation of hospital care (emergency, inpatient and outpatient), for managing children presenting with diarrhea and pneumonia at 13 district hospitals in India. DESIGN:Facility-Based assessment of district hospitals. SETTINGS:13 district hospitals in four states of Biha...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2021-01-02 00:00:00
abstract:OBJECTIVE:To describe the clinical profile of children with bacteriologically confirmed tuberculosis. STUDY DESIGN:A multicentric study was conducted in three hospitals in Chennai city between July 1995 and December 1997. Children aged 6 months to 12 years with signs and symptoms suggestive of tuberculosis were invest...
journal_title:Indian pediatrics
pub_type: 杂志文章,多中心研究
doi:
更新日期:2008-09-01 00:00:00