Abstract：
OBJECTIVE:To describe the clinical profile of children with bacteriologically confirmed tuberculosis. STUDY DESIGN:A multicentric study was conducted in three hospitals in Chennai city between July 1995 and December 1997. Children aged 6 months to 12 years with signs and symptoms suggestive of tuberculosis were investigated further. Clinical examination, chest radiograph, tuberculin skin test with 1 TU PPD and, sputum or gastric lavage for mycobacterial smear and culture were done for all and, lymph node biopsy when necessary. RESULTS:A total of 2652 children were registered and tuberculosis was bacteriologically confirmed in 201. Predominant symptoms were history of an insidious illness (49%), fever and cough (47%), loss of weight (41%) and a visible glandular swelling (49%). Respiratory signs were few and 62% were undernourished. Over half the patients with confirmed TB had normal chest X-ray. Abnormal X-ray findings included parenchymal opacities in 47% and hilar or mediastinal lymphadenopathy in 26%. The prevalence of isoniazid resistance was 12.6% and MDR TB 4%. CONCLUSIONS:Children with tuberculosis present with fever and cough of insidious onset. Lymphadenopathy is a common feature even in children with pulmonary TB. A significant proportion of children have normal chest X-rays despite positive gastric aspirate cultures. Drug resistance rates in children mirror the pattern seen in adults in this geographic area.
journal_name
Indian Pediatrjournal_title
Indian pediatricsauthors
Swaminathan S,Datta M,Radhamani MP,Mathew S,Reetha AM,Rajajee S,Mathew R,Radhakrishnan A,Raghu MBsubject
Has Abstractpub_date
2008-09-01 00:00:00pages
743-7issue
9eissn
0019-6061issn
0974-7559journal_volume
45pub_type
杂志文章,多中心研究abstract：:We observed a significant fall in neonatal mortality in babies weighing less than 2 kg during 1986 as compared to 1973 (7.94% vs 12.88%; p less than 0.005), and in preterm babies the mortality fell from 26.88 to 11.5% (p less than 0.001) during 1986. This was achieved despite 2-3 fold increase in the high risk babies ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1989-03-01 00:00:00
abstract：OBJECTIVE:To assess the safety and immunogenicity of a quadrivalent meningococcal (groups A,C,Y,W) polysaccharide diphtheria toxoid conjugate vaccine (MenACYW-DT) in India. DESIGN:Open-label, descriptive, non-randomized study. SETTING:Three medical college hospitals, one each in New Delhi, Bengaluru and Mumbai, India...
journal_title：Indian pediatrics
pub_type： 杂志文章,多中心研究
doi：10.1007/s13312-014-0435-7
更新日期：2014-06-01 00:00:00
abstract：:Five hundred ninety two children (6.0%) were diagnosed as persistent diarrhea (PD) out of a total attendance of 9795 cases in the Diarrhea Training and Treatment Unit (DTU) over a period of 1 year. Most of the cases were initially managed as outpatients on dietary advice and treatment of associated infections. Eighty ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1995-03-01 00:00:00
abstract：OBJECTIVE:To study the clinical spectrum and management of choledochal cyst in children below 12 years of age. DESIGN:Descriptive study. SETTING:Tertiary care hospital. METHODS:Twenty three children with choledochal cysts were managed between January 1991 to September 1997 and their clinical details, investigations ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1998-07-01 00:00:00
abstract：BACKGROUND:Management of pyothorax and pneumothorax requires aspiration and/or intercostal drainage. CASE CHARACTERISTICS:We present two cases which were complicated by instrument-related events resulting in breakage of needle or intercostal drainage tube resulting in pleural foreign body. INTERVENTION/OUTCOME:The pa...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-016-0848-6
更新日期：2016-04-01 00:00:00
abstract：BACKGROUND:High bilirubin level is toxic to developing brain and auditory system but the current debate surrounds the toxicity of bilirubin in healthy term infants. METHODS:Longitudinal observational study to find BERA abnormalities in term newborns with isolated hyperbilirubinemia of 20 mg/dL and more and to follow u...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-014-0346-7
更新日期：2014-02-01 00:00:00
abstract：:This study was conducted in 2006 to assess the current iodine nutriure of the population in Haryana by assessing the urinary iodine excretion levels amongst the school age children between 6-12 years. Altogether 3,019 urine samples were collected from all the 19 districts in Haryana. The urinary iodine was analyzed by...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2009-01-01 00:00:00
abstract：:We studied the actual time taken to document temperature in a stable neonate by an electronic digital skin thermometer with automatic time beeper. We studied 100 neonates after initial stabilization. The mean time required for documenting the temperature by a electronic thermometer in axilla was 56.34+/-1.54 secs for ...
journal_title：Indian pediatrics
pub_type： 信件
doi：
更新日期：2009-12-01 00:00:00
abstract：BACKGROUND:Glycogen storage disease type VI (GSD-VI) presents with failure to thrive and also fibrosis in some cases, without cirrhosis. CASE CHARACTERISTICS:2½-year-old girl presented with short stature, transaminase elevation and significant fibrosis, suggesting GSD-III. OBSERVATION:A pathogenic mutation in PYGL ge...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-017-1174-3
更新日期：2017-09-15 00:00:00
abstract：:Congenital hypoparathyroidism, growth retardation and dysmorphism is a rare autosomal recessive syndrome among Arab population commonly known as Sanjad-Sakati syndrome(SSS).Several metabolic and septic complications are known to manifest in the neonatal age. We describe the first report of morbid pathological fracture...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-010-0066-6
更新日期：2010-05-01 00:00:00
abstract：:Eighty one pregnant women (20 +/- 2 weeks of gestation) were assessed for their nutritional status. They were divided into three groups; Group I women (n = 30) were given 200 mg ferrous sulphate (FeSO4) tablet per day for 15 weeks, Group II women (n = 25) were given FeSO4 tablets along with 2,000,000 IU of vitamin A a...
journal_title：Indian pediatrics
pub_type： 临床试验,杂志文章
doi：
更新日期：1995-08-01 00:00:00
abstract：BACKGROUND:Neuroschistosomiasis is an uncommonly reported disease. CASE CHARACTERISTICS:An adolescent Indian boy residing in Kenya presented with headache, visual symptoms and seizures, with MRI showing space-occupying lesions in the occipital lobe and cerebellum. OBSERVATION:Brain biopsy was diagnostic of neuro-schi...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2018-11-15 00:00:00
abstract：:We report a case of toxic epidermal necrolysis who was successfully treated with intravenous immunoglobin and granulocyte colony-stimulating factor. He had poor prognostic factors such as extensive epidermal loss, neutropenia, acute respiratory distress syndrome and candida sepsis, but nonetheless made a complete reco...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2004-04-01 00:00:00
abstract：:To identify an inexpensive, reliable predictor of low birth weight capable of being utilized by untrained personnel, anthropometric measures were performed on 1600 newborns in Kanpur, India. This analysis indicated that, for a birth weight of 2500 g, the critical limit of calf circumference was 10.8 cm or less. Crit...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1996-02-01 00:00:00
abstract：:Hospital acquired enteric infections were investigated by studying 3138 children under 5 years of age who were admitted without diarrhea in nine medical words of a pediatric hospital, Calcutta during the period between March and September 1987. Three hundred and twenty (10.2%) children developed nosocomial diarrhea du...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1993-02-01 00:00:00
abstract：:The clinical, angiographic and computed tomographic features in eight children with Moyamoya disease were evaluated. The CT Scan findings were correlated with the angiographic features and the stage of the vascular disease. Stenosis/occlusion of the supraclinoid internal carotid artery (ICA) and the proximal parts of ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1995-04-01 00:00:00
abstract：CONTEXT:Measles remains a major cause of child mortality in India. Measles case fatality ratios (CFRs) vary substantially between countries and even within the same community over time. We present a review of Indian community-based measles CFR studies conducted from 1975 to 2008. EVIDENCE ACQUISITION:PubMed, Cochrane ...
journal_title：Indian pediatrics
pub_type： 杂志文章,评审
doi：
更新日期：2009-11-01 00:00:00
abstract：:A retrospective analysis was carried out to identify factors associated with delay in diagnosis of Kawasaki disease in a tertiary care pediatric hospital setting in Chennai, India. Over a period of 2 years, a total of 37 cases were studied. The cases were divided into Early Diagnosis Group (EDG) and Delayed Diagnosis ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-012-0130-5
更新日期：2012-08-01 00:00:00
abstract：JUSTIFICATION:Gaucher disease (GD) is amongst the most frequently occurring lysosomal storage disorder in all ethnicities. The clinical manifestations and natural history of GD is highly heterogeneous with extreme geographic and ethnic variations. The literature on GD has paucity of information and optimal management g...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2018-02-15 00:00:00
abstract：:Twenty children of acute viral hepatitis were subjected to ultrasound of gall bladder in acute and recovery phase. Increased wall thickness, reduced volume and abnormal echo-texture of gall bladder contents were the findings in the acute phase. A normal ultrasound of gall bladder was restored in most of the patients w...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1989-07-01 00:00:00
abstract：OBJECTIVE:To study the effect of zinc supplementation in children under 5 years of age rom low- and middle-income countries (LMICs) on anthropometry and prevalence of malnutrition. Design:Systematic review of randomized controlled trials and cluster randomized trials. SETTING:Low- and middle-income countries. PARTIC...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2019-05-15 00:00:00
abstract：:A study of infant feeding practices was carried out as part of a larger longitudinal study of an urban birth cohort in an area of South Delhi, India. 802 mothers of children over 1 year of age were selected randomly for interview. The study group is considered to be a representative sampling of the economic, cultura...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1976-11-01 00:00:00
abstract：OBJECTIVE:To describe a novel wrist deformity in b-thalassemia major patients, and their radiographic and magnetic resonance imaging findings. METHODS:30 patients with b-thalassemia major who were noticed to have ulnar deviation at wrist joint were evaluated for previous history of medications, serum ferritin levels, ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2019-01-15 00:00:00
abstract：BACKGROUND:Fetal growth restriction and abnormal Doppler flow studies are commonly associated. Neonatal outcomes are not well known particularly in developing countries, where the burden of the disease is the highest. OBJECTIVE:To determine outcomes of preterm infants with history of absent/reversed end-diastolic umbi...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-013-0235-5
更新日期：2013-09-01 00:00:00
abstract：:Seven cases of benign form of spinal muscular atrophy were studied to evaluate the importance of detecting hand tremors, muscle fasciculation, evertion of foot and ECG tremors to distinguish these cases from muscular dystrophy. Taken in combination, diagnosis of all the seven cases was possible without the need for ap...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1989-10-01 00:00:00
abstract：OBJECTIVE:To study the clinical profile of children with scrub typhus and its association with hemophagocytic lymphohistiocytosis. METHODS:Children presenting with unexplained fever and multi-systemic involvement between May to December 2011 were tested for scrub typhus using IgM ELISA kits. Occurrence of Hemophagocyt...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-014-0470-4
更新日期：2014-08-01 00:00:00
abstract：:Thrombocytosis is a frequent finding in hemograms obtained from hospitalized and ambulatory children due to the widespread use of automated blood cell counters. Pediatricians are commonly puzzled in cases of thrombocytosis to determine the underlying cause and the need for therapy. The purpose of this review is to ass...
journal_title：Indian pediatrics
pub_type： 杂志文章,评审
doi：
更新日期：2008-08-01 00:00:00
abstract：OBJECTIVE:To assess the epidemiological and clinical characteristics of pediatric inpatients with COVID-19, early in the pandemic. METHODS:Clinical and laboratory profile and outcomes were studied for children (aged 1 month - 18 years) presenting between 1 April, 2020 and 20 May, 2020 with positive nasopharyngeal swab...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2020-10-15 00:00:00
abstract：OBJECTIVE:To evaluate the effect of high dose phenobarbital on lipid peroxidation and antioxidant enzymes in perinatal asphyxia. DESIGN:Open label, Randomized controlled trial. SETTING:Neonatal intensive care unit of a tertiary care teaching hospital. PARTICIPANTS:72 full term inborn neonates with severe birth asphy...
journal_title：Indian pediatrics
pub_type： 杂志文章,随机对照试验
doi：10.1007/s13312-011-0106-x
更新日期：2011-08-01 00:00:00
abstract：OBJECTIVE:To evaluate recovery and survival of severely wasted children without community management of acute malnutrition programme. DESIGN:Single time point follow-up (24th December 2013 - 2nd April, 2014) of severely wasted children identified in a community-based cross-sectional survey (September 2012 - October 20...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-017-1142-y
更新日期：2017-10-15 00:00:00
