Tumor necrosis factor alpha and interleukin 6 in infants with sepsis.

Abstract:

:Thirty-two infants above one month of age admitted to a tertiary care hospital with signs of infection and presumptive diagnosis of sepsis were included. Cytokine levels of tumor necrosis factor alpha (TNFmu) and interleukin-6 (IL 6) were estimated at admission and after 48 to 72 hr, and their relationship examined to the outcome. Significantly higher TNFalpha and IL-6 levels were seen in infants with sepsis compared to control. The TNFalpha levels significantly decreased in patients with sepsis, septic shock and the survivors, while the patients who did not survive, the levels showed no significant change after 48 hr. The initial levels of IL6 were comparatively higher in patients with septic shock and non-survivors, and increased at 48 hr of admission in patients with sepsis, septic shock and non-survivors.

journal_name

Indian Pediatr

journal_title

Indian pediatrics

authors

Makhija P,Yadav S,Thakur A

keywords:

subject

Has Abstract

pub_date

2005-10-01 00:00:00

pages

1024-8

issue

10

eissn

0019-6061

issn

0974-7559

journal_volume

42

pub_type

杂志文章
  • Pulmonary sarcoidosis masquerading as tuberculosis.

    abstract::Pulmonary manifestations of sarcoidosis are common and may be initially confused with other common diseases like tuberculosis. We report an 11 yr old girl who presented with chronic cough, low grade fever, recent exposure to tuberculosis and hilar lymphadenopathy. She was provisionally diagnosed as pulmonary tuberculo...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Singh M,Kothur K

    更新日期:2007-08-01 00:00:00

  • A modified technique for umbilical arterial catheterization.

    abstract::A modified technique for umbilical artery catheterization was assessed in babies in whom conventional method failed or if the cord was dry. Success rate attained with the modified technique was 90% (19/21). This modified technique could provide an easier and faster method for successful umbilical arterial catheterizat...

    journal_title:Indian pediatrics

    pub_type: 信件

    doi:10.1007/s13312-014-0477-x

    authors: Gupta V,Kumar N,Jana AK,Thomas N

    更新日期:2014-08-01 00:00:00

  • Abdominal tuberculosis in children: experience over a decade.

    abstract::This presentation deals with 110 surgically proven cases of abdominal tuberculosis in the pediatric age group. The protean clinical profiles and complications of the disease entity made the clinical diagnosis difficult; the investigations were also found non-pathognomonic. The most common type of pathology seen was ad...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Sharma AK,Agarwal LD,Sharma CS,Sarin YK

    更新日期:1993-09-01 00:00:00

  • Transcutaneous absorption of topically massaged oil in neonates.

    abstract:OBJECTIVE:To study the transcutaneous absorption of traditionally massaged oil in newborns and to specifically compare the effects of (i) essential fatty acid (EFA) rich - safflower oil and (ii) saturated fat rich coconut oil, on fatty acid profiles of massaged babies. DESIGN:A short term randomised controlled study. ...

    journal_title:Indian pediatrics

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Solanki K,Matnani M,Kale M,Joshi K,Bavdekar A,Bhave S,Pandit A

    更新日期:2005-10-01 00:00:00

  • Bone Mineral Density of Indian Children and Adolescents with Cystic Fibrosis.

    abstract:OBJECTIVE:To document bone mineral density of children and adolescents with cystic fibrosis. DESIGN:Cross-sectional study. SETTING:Tertiary-care center of Northern India, July 2012 to August 2015. PARTICIPANTS:52 children aged 6-18 years with cystic fibrosis and 62 healthy controls of similar age and sex. METHODS:B...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:10.1007/s13312-017-1065-7

    authors: Gupta S,Mukherjee A,Khadgawat R,Kabra M,Lodha R,Kabra SK

    更新日期:2017-07-15 00:00:00

  • Optimum age of a child for BCG vaccination.

    abstract::The objectives of this study were to evaluate whether a newborn or a neonate is capable of responding immunologically after BCG vaccination and to find out if this immunity persists for one year. Normal infants aged between 0 days-3 months brought to immunization centre were included in the study. In vitro leukocyte m...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Vijayalakshmi V,Kumar S,Kiran AL,Rani HS,Murthy KJ

    更新日期:1994-12-01 00:00:00

  • Child labor in suburban areas of Calcutta, West Bengal.

    abstract::Seven hundred and fifty nine children in different sectors were covered in this study, which was undertaken by observational techniques, questionnaires and physical examination. All children belonged to the age group of 6-14 years. Nearly 30% children had migrated from neighbouring districts and states. Almost 88% wer...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Banerjee SR

    更新日期:1991-09-01 00:00:00

  • Ferrous sulfate versus iron polymaltose complex for treatment of iron deficiency anemia in children.

    abstract::We assessed the clinical response and side effects of Ferrous sulfate (FS) and Iron polymaltose complex (IPC) in 118 children with Iron deficiency anemia (IDA). Subjects were randomized to receive therapy with either oral IPC (Group A, n=59) or oral FS (Group B, n=59); all were given elemental iron in three divided do...

    journal_title:Indian pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:

    authors: Bopche AV,Dwivedi R,Mishra R,Patel GS

    更新日期:2009-10-01 00:00:00

  • Thrombocytosis in childhood.

    abstract::Thrombocytosis is a frequent finding in hemograms obtained from hospitalized and ambulatory children due to the widespread use of automated blood cell counters. Pediatricians are commonly puzzled in cases of thrombocytosis to determine the underlying cause and the need for therapy. The purpose of this review is to ass...

    journal_title:Indian pediatrics

    pub_type: 杂志文章,评审

    doi:

    authors: Mantadakis E,Tsalkidis A,Chatzimichael A

    更新日期:2008-08-01 00:00:00

  • Significance of cord problems at birth.

    abstract::Cord problems at birth were prospectively studied in 12,000 singleton deliveries, of which 258 (2.15%) babies had cord abnormalities. Nearly 32% of these cases had fetal distress and 20.5% had 1 minute Apgar score less than 6. Of the various cord problems nuchal cord was noted in 79.1%, cord prolapse in 12.4% and true...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Kumari S,Saxena A,Monga D,Malik A,Kabra M,Kurray RM

    更新日期:1992-03-01 00:00:00

  • Crusade against Malnutrition: Nutrition Education Program.

    abstract::A holistic approach in assessment and plan for intervention in childhood malnutrition is the need of the hour. This is in the context of nutrition education program (NEP), undertaken under the National IAP action plan, 2015. In the crusade against malnutrition, an ABCDEFQ assessment scale is recommended, with aspects ...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:10.1007/s13312-016-0820-5

    authors: Elizabeth KE

    更新日期:2016-03-01 00:00:00

  • Bone metabolism in cow milk allergic children.

    abstract::Children with cow milk allergy are suspected to develop calcium metabolism disturbances. We observed increased markers of bone turnover in these children. Children with cow milk allergy are more prone to develop the disturbances of the bone mineralization even in the first year of life. ...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:10.1007/s13312-013-0194-x

    authors: Jakusova L,Jesenak M,Schudichova J,Banovcin P

    更新日期:2013-07-01 00:00:00

  • A profile of bacteriologically confirmed pulmonary tuberculosis in children.

    abstract:OBJECTIVE:To describe the clinical profile of children with bacteriologically confirmed tuberculosis. STUDY DESIGN:A multicentric study was conducted in three hospitals in Chennai city between July 1995 and December 1997. Children aged 6 months to 12 years with signs and symptoms suggestive of tuberculosis were invest...

    journal_title:Indian pediatrics

    pub_type: 杂志文章,多中心研究

    doi:

    authors: Swaminathan S,Datta M,Radhamani MP,Mathew S,Reetha AM,Rajajee S,Mathew R,Radhakrishnan A,Raghu MB

    更新日期:2008-09-01 00:00:00

  • Potential factors related to waist circumference in urban South Indian children.

    abstract:OBJECTIVES:To identify important factors (linked to lifestyle, eating and sedentary behaviors) relating to waist circumference among urban South Indian children aged 3 to 16 years. DESIGN:Cross sectional. SETTING:Urban schools of Bangalore, from August 2008 to January 2010. PARTICIPANTS:8444 children; 4707 children ...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:10.1007/s13312-012-0027-3

    authors: Kuriyan R,Thomas T,Sumithra S,Lokesh DP,Sheth NR,Joy R,Bhat S,Kurpad AV

    更新日期:2012-02-01 00:00:00

  • Guidelines for diagnosis and management of childhood epilepsy.

    abstract:JUSTIFICATION:Seizures constitute the most common neurological problem in children and the majority of epilepsy has its onset in childhood. Appropriate diagnosis and management of childhood epilepsy is essential to improve quality of life in these children. Evidence-based clinical practice guidelines, modified to the I...

    journal_title:Indian pediatrics

    pub_type: 杂志文章,实务指引

    doi:

    authors: Expert Committee on Pediatric Epilepsy, Indian Academy of Pediatrics.

    更新日期:2009-08-01 00:00:00

  • Epidemiology of Cryptosporidium in Pediatric Diarrheal Illnesses.

    abstract:CONTEXT:Cryptosporidium spp. is a zoonotic infection, now being recognized as a significant cause of diarrhea in both immunocompetent and immunocompromised hosts. However, there still exist significant knowledge gaps in its estimated global burden, epidemiology, diagnosis and management. EVIDENCE ACQUISITION:A semi-sy...

    journal_title:Indian pediatrics

    pub_type: 杂志文章,评审

    doi:10.1007/s13312-017-1093-3

    authors: Dabas A,Shah D,Bhatnagar S,Lodha R

    更新日期:2017-04-15 00:00:00

  • Factors associated with delay in diagnosis of Kawasaki disease in India.

    abstract::A retrospective analysis was carried out to identify factors associated with delay in diagnosis of Kawasaki disease in a tertiary care pediatric hospital setting in Chennai, India. Over a period of 2 years, a total of 37 cases were studied. The cases were divided into Early Diagnosis Group (EDG) and Delayed Diagnosis ...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:10.1007/s13312-012-0130-5

    authors: Balasubramanian S,Krishna MR,Dhanalakshmi K,Amperayani S,Ramanan AV

    更新日期:2012-08-01 00:00:00

  • Association of Rotavirus Gastroenteritis with Histo-blood Group Antigens.

    abstract::Association of rotavirus gastroenteritis with histo-blood group antigens in children younger than 5 years admitted with diarrhea (n=389) was studied. Distribution of blood groups in rotavirus positive (n=96) and rotavirus negative (n=51) diarrhea gastroenteritis cases did not show any susceptibility to any blood group...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Mohanty E,Dwibedi B,Kar SK,Pandey RM

    更新日期:2016-07-08 00:00:00

  • Mucoepidermoid Carcinoma of Parotid as a Second Malignancy in Acute Lymphoblastic Leukemia.

    abstract:BACKGROUND:Improved survival seen in Acute Lymphoblastic Leukemia (ALL) cases has led to increased reports of second malignant neoplasms. CASE CHARACTERISTICS:A 12-year-old female treated for ALL using UK ALL XI protocol nine years back presented with progressively increasing pre-auricular swelling. OBSERVATION:Inves...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:10.1007/s13312-015-0757-0

    authors: Tikku G,Jain D,Kumari A,Grover R

    更新日期:2015-11-01 00:00:00

  • Use of Learning Platforms for Quality Improvement.

    abstract::Ensuring quality in healthcare today has become extremely essential to ensure adequate utilization of healthcare services and improved outcomes. In addition to essential infrastructure in terms of safe and adequate space, knowledgeable and skilled health workers, and essential equipment and supply, the healthcare team...

    journal_title:Indian pediatrics

    pub_type: 杂志文章,评审

    doi:

    authors: Mehta R,Sharma KA

    更新日期:2018-09-15 00:00:00

  • Pottels Equation for Estimation of Glomerular Filtration Rate.

    abstract::The retrospective study was carried out to examine performance of Pottels height- independent equation compared to Schwartzs height-dependent equation to estimate glomerular filtration rate in 115 children in Indian setting. The Pottels equation performed well compared to updated Schwartz equation (R2=0.94, mean bias ...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:10.1007/s13312-017-1001-x

    authors: Barman H,Bisai S,Das BK,Nath CK,Duwarah SG

    更新日期:2017-01-15 00:00:00

  • Acute myeloid leukemia presenting as obstructive jaundice.

    abstract::Jaundice as a presenting feature of pediatric acute myeloid leukemia is rare. We report two cases of AML who presented with obstructive jaundice, one with a malignant stricture at the common bile duct and other with a granulocytic sarcoma obstructing the bile duct. The prognosis is poor in these patients. ...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Rajeswari B,Ninan A,Prasannakumari SN,Parukuttyamma K

    更新日期:2012-05-01 00:00:00

  • Prospective study of nosocomial enteric infections in a pediatric hospital, Calcutta.

    abstract::Hospital acquired enteric infections were investigated by studying 3138 children under 5 years of age who were admitted without diarrhea in nine medical words of a pediatric hospital, Calcutta during the period between March and September 1987. Three hundred and twenty (10.2%) children developed nosocomial diarrhea du...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Dutta P,Mitra U,Rasaily R,Bhattacharya SK,De SP,Sen D,Saha MR,Nair GB,Niyogi SK,Das P

    更新日期:1993-02-01 00:00:00

  • Lysinuric Protein Intolerance Presenting with Recurrent Hyperammonemic Encephalopathy.

    abstract:BACKGROUND:Lysinuric protein intolerance is an inherited disorder of transport of cationic amino acids, causing amino aciduria. CASE CHARACTERISTICS:A 3-year-old boy with 12 month history of episodic change in behavior (decreased sleep, poor interaction), stunted growth and hyperammonemia. OUTCOME:Genetic analysis re...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:10.1007/s13312-016-0920-2

    authors: Bijarnia-Mahay S,Jain V,Bansal RK,Reddy GM,Haberle J

    更新日期:2016-08-08 00:00:00

  • Langerhans cell histiocytosis in children less than 2 years of age.

    abstract:OBJECTIVE:To study the clinical profile and outcome of langerhans cell histiocytosis in children upto 2 years of life. DESIGN:Retrospective analysis. METHODS:Medical records of Children upto 2 years of age with a diagnosis of langerhans cell histiocytosis (LCH) were analyzed. Their clinical pattern, treatment modalit...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Kusuma Kumary P,Priyakumari T,Chellam VG,James FV,Nair MK

    更新日期:1999-01-01 00:00:00

  • 50 years of tuberculosis control in India: progress, pitfalls and the way forward.

    abstract::India established the National Tuberculosis Control Project (NTCP) 50 years ago and re-designed it as Revised NTCP (RNTCP) 19 years ago. Tuberculosis (TB) control was beset with obstacles-BCG vaccination was found ineffective in TB control in 1979; human immunodeficiency virus began spreading in India since 1984 with ...

    journal_title:Indian pediatrics

    pub_type: 历史文章,杂志文章

    doi:10.1007/s13312-013-0021-4

    authors: John TJ,Vashishtha VM,John SM

    更新日期:2013-01-08 00:00:00

  • Transfusion associated graft versus host disease.

    abstract::Transfusion-associated graft-versus-host disease (TA-GVHD) is a dreaded complication in immunocompromized hosts. The diagnosis is often delayed because of lack of awareness and the non-specific clinical features. More than 90% patients succumb to refractory infections. The only effective preventive measure is administ...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Gupta A,Bansal D,Dass R,Das A

    更新日期:2004-12-01 00:00:00

  • Wrist Deformity in Children and Adolescents with b-thalassemia on Oral Iron Chelation Therapy.

    abstract:OBJECTIVE:To describe a novel wrist deformity in b-thalassemia major patients, and their radiographic and magnetic resonance imaging findings. METHODS:30 patients with b-thalassemia major who were noticed to have ulnar deviation at wrist joint were evaluated for previous history of medications, serum ferritin levels, ...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Merchant RH,Kulkarni A,Doctor PN,Choudhari A,Patkar DP

    更新日期:2019-01-15 00:00:00

  • Sly Disease: Mucopolysaccharidosis Type VII.

    abstract::A 6 month-old infant presenting with severe mitral regurgitation was found to have hepatosplenomegaly, corneal clouding, and Alder-Reilly granules in the leucocytes. Extremely low levels of beta glucuronidase confirmed the diagnosis of Sly disease (Mucopolysaccharidosis VII). This is the first case of MPS VII reported...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:

    authors: Nampoothiri S,Kappanayil M,Hiran KR,Sunitha V

    更新日期:2008-10-01 00:00:00

  • Clinical profile of scrub typhus in children and its association with hemophagocytic lymphohistiocytosis.

    abstract:OBJECTIVE:To study the clinical profile of children with scrub typhus and its association with hemophagocytic lymphohistiocytosis. METHODS:Children presenting with unexplained fever and multi-systemic involvement between May to December 2011 were tested for scrub typhus using IgM ELISA kits. Occurrence of Hemophagocyt...

    journal_title:Indian pediatrics

    pub_type: 杂志文章

    doi:10.1007/s13312-014-0470-4

    authors: Sankhyan N,Saptharishi LG,Sasidaran K,Kanga A,Singhi SC

    更新日期:2014-08-01 00:00:00