Abstract:
:The objectives of this study were to evaluate whether a newborn or a neonate is capable of responding immunologically after BCG vaccination and to find out if this immunity persists for one year. Normal infants aged between 0 days-3 months brought to immunization centre were included in the study. In vitro leukocyte migration inhibition test was performed in these children using Phytohemagglutinin and purified protein derivative (PPD). They were grouped based on their age at vaccination, their LMI values and on the time interval after vaccination. The mean values of % LMI (PPD) in all the age groups were positive and there were no significant differences between the newborns, the neonates and other groups. The values were positive and comparable even after 12 months in all the groups. The percentage of infants with positive or negative values to LMI (PHA) and negative values to LMI (PPD) were also comparable at different time intervals in different age groups. The results suggest that newborns or neonates are as capable of eliciting a positive immune response after BCG vaccination, as older infants and the practise of vaccinating a child at birth could be continued.
journal_name
Indian Pediatrjournal_title
Indian pediatricsauthors
Vijayalakshmi V,Kumar S,Kiran AL,Rani HS,Murthy KJsubject
Has Abstractpub_date
1994-12-01 00:00:00pages
1497-501issue
12eissn
0019-6061issn
0974-7559journal_volume
31pub_type
杂志文章abstract:OBJECTIVE:To evaluate the effect of canakinumab on growth parameters of patients with autoinflammatory diseases. METHODS:This retrospective study included Colchicine resistant familial Mediterranean fever (FMF), Mevalonate kinase deficiency (MKD), Tumor necrosis factor receptor-associated periodic fever syndrome (TRAP...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2020-07-15 00:00:00
abstract:OBJECTIVE:To assess the efficacy of nasal intermittent positive pressure ventilation with heliox in preterm infants with respiratory distress syndrome. METHODS:Premature infants with mild respiratory distress syndrome requiring non-invasive respiratory support were eligible. Infants were randomly assigned to heliox or...
journal_title:Indian pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1007/s13312-014-0524-7
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVE:To determine whether interactional group discussions could reduce prescriptions of injections by physicians. STUDY DESIGN:Randomized controlled trial. SETTING:Rural public health care facilities, North 24 Parganas district, West Bengal, India. SUBJECTS:72 medical officers, 36 each in intervention and contr...
journal_title:Indian pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1007/s13312-010-0076-4
更新日期:2010-05-01 00:00:00
abstract:BACKGROUND:Human trypansomiasis due to infection by animal trypanosomes is rarely reported from India. CASE CHARACTERISTICS:We describe clinical presentation of a 2-month-old boyfrom a rat infested house in rural Gujarat who was diagnosed to be havinginfection with the rodent parasite Trypanosoma lewisi. OBSERVATION:...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2018-01-15 00:00:00
abstract::In this study, 78 middle ear aspiration samples from 59 children between the ages of 2 14 who have undergone myringotomy under general anesthesia were included. The presence of DNA genome of Chlamydia trachomatis was analyzed with polymerase chain reaction in the aspiration material. The relationship between the natur...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2005-07-01 00:00:00
abstract:JUSTIFICATION:Separate guidelines are needed for determining the optimal timing of intervention in children with congenital heart diseases in India, because of their frequent late presentation, undernutrition and co-existing morbidities. PROCESS:Guidelines emerged following expert deliberations at the National Consens...
journal_title:Indian pediatrics
pub_type: 杂志文章,实务指引
doi:
更新日期:2008-02-01 00:00:00
abstract::Acute interstitial nephritis (AIN) should be ruled out in children with unexplained acute renal failure. We present a 4 1/2 year old girl who presented with oliguric acute renal failure preceded by a febrile illness. Renal histopathology revealed features of drug induced AIN. She recovered with dialysis, other support...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2003-04-01 00:00:00
abstract::Hypocalcemia is a curable cause of myocardial dysfunction and clinical congestive cardiac failure, with only stray reports available in literature. We describe 15 infants presenting with severe left ventricular dysfunction, who were found to have hypocalcemia with or without hypomagnesemia. Vitamin D deficiency was id...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-010-0117-z
更新日期:2010-09-01 00:00:00
abstract::The phenotypic description of SHORT syndrome (OMIM- 269880) is expanding since its initial description in 1975. There have been 26 case reports till date but the genetic locus of this syndrome is elusive. Involvement of PITX2 gene initially envisaged is probably is not the only gene involved but has an important role ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-013-0099-8
更新日期:2013-04-01 00:00:00
abstract::Seventy five mothers with lactation failure were studied, whose less than 4-month-old babies were admitted to the hospital. Partial lactational failure (94.7%) was noted more often than complete lactational failure (5.3%). Initiation of breastfeeding was delayed for 2 to 5 days usually for traditional reasons (77.3%) ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1992-12-01 00:00:00
abstract::India has been emphasizing the interrelationship between primary health care, maternal and child health, and family planning as the major problem for family welfare. Family welfare has been adopted at the national level by the government. Integration of these 2 components of family welfare maternal and child health ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1983-06-01 00:00:00
abstract::We report on long-term follow-up [mean (SD) duration, 44.7 (4.3) mo] of 48 out of 132 children with recurrent abdominal pain, who were a part of an earlier study at our hospital. 31 (64.5%) children still experienced pain; 26 (54.1%) reported their pain to be better than before, 4 children reported it to be same as be...
journal_title:Indian pediatrics
pub_type: 信件
doi:
更新日期:2020-05-15 00:00:00
abstract:BACKGROUND:Blue rubber bleb nevus syndrome is a rare clinical entity. CASE CHARACTERISTICS:A 13-year-old Indian boy presented with characteristic cutaneous lesions, gastrointestinal malformations, skeletal involvement and pulmonary stenosis. OBSERVATIONS:Diagnosis was confirmed on skin biopsy, radiographic evaluation...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-016-0884-2
更新日期:2016-06-08 00:00:00
abstract:UNLABELLED:Iron supplementation programs using pediatric tablets or drops have not been successful in the control of anemia amongst infants and children in India. Sprinkles is an innovative multi-micronutrient home fortification strategy to control iron deficiency and anemia. OBJECTIVE:We aimed to determine the hemato...
journal_title:Indian pediatrics
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2007-02-01 00:00:00
abstract::Hot water epilepsy (HWE) is a rare form of reflex epilepsy caused by bathing with hot water. In this paper, we describe three cases with hot water epilepsy. It occurs generally in children with normal psychomotor development and children continue to develop normally after seizure. HWE has usually a favorable prognosis...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2004-07-01 00:00:00
abstract::Hepatitis is a known manifestation of congenital syphilis, however hepatitis developing during penicillin therapy is unknown. Ten patients of congenital syphilis were studied and serial liver enzymes were done before and after starting penicillin therapy. Eight of the ten patients developed hepatitis after initiating ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1991-02-01 00:00:00
abstract:OBJECTIVE:To document bone mineral density of children and adolescents with cystic fibrosis. DESIGN:Cross-sectional study. SETTING:Tertiary-care center of Northern India, July 2012 to August 2015. PARTICIPANTS:52 children aged 6-18 years with cystic fibrosis and 62 healthy controls of similar age and sex. METHODS:B...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-017-1065-7
更新日期:2017-07-15 00:00:00
abstract::Thirty six neonates with severe birth asphyxia (Apgar score less than or equal to 3 at 1 min), 32 with moderate birth asphyxia (Apgar score 4 to 6 at 1 min) and 35 controls (Apgar score greater than or equal to 7 at 1 min) matched for weight and gestation were followed up prospectively for neurodevelopmental outcome. ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1989-08-01 00:00:00
abstract::Youth violence is a growing problem worldwide. Research on adolescent violence in India is limited. Fifteen hundred high school students were investigated to study the prevalence and demographic characteristics of witnesses, victims and perpetrators of violence and to see the impact of violence exposure on their psych...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2006-07-01 00:00:00
abstract::The morbidity pattern and nutritional profile was evaluated of school children who resided around Mosaboni Copper Mines and in surrounding villages of Ghatsila subdivision in Singhbhum district of Bihar State, India. A total of 1424 school children (816 boys and 608 girls) between 5-17 years old were studied. Children...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1989-06-01 00:00:00
abstract::Andersen Tawil syndrome is a rare type of channelopathy characterized by the presence of periodic paralysis, cardiac arrhythmia (prolonged QT interval or ventricular arrhythmia) and distinct dysmorphic abnormalities. It is a type of potassium channelopathy that occurs sporadically or by autosomal dominant inheritance....
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-011-0008-y
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Auxiliary partial orthotopic liver transplantation is a technique where part of diseased native liver is removed and replaced with healthy donor liver so that, the left behind native liver could later regenerate. CASE CHARACTERISTICS:2 year 6 month old girl with acute liver failure due to Hepatitis A. She u...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-016-0795-2
更新日期:2016-01-01 00:00:00
abstract::A quadrivalent MMRV (measles-mumps-rubella-varicella) combination vaccine has recently been launched in India. This vaccine is highly immunogenic, with seroconversion rates against all antigens reaching 96.6-100% at 42 to 56 days after the second vaccine dose in unvaccinated children or in those previously vaccinated ...
journal_title:Indian pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s13312-017-1209-9
更新日期:2017-12-15 00:00:00
abstract::The clinical, angiographic and computed tomographic features in eight children with Moyamoya disease were evaluated. The CT Scan findings were correlated with the angiographic features and the stage of the vascular disease. Stenosis/occlusion of the supraclinoid internal carotid artery (ICA) and the proximal parts of ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1995-04-01 00:00:00
abstract::We conducted this study to find out the incidence of extubation failure (EF) in ventilated neonates and associated clinical risk factors. Eighty two ventilated neonates were followed up to 48 hours post extubation to look for EF. Twenty two babies (26.8%) had EF. The common risk factors for EF were presence of patent ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2009-10-01 00:00:00
abstract:OBJECTIVE:To study the transcutaneous absorption of traditionally massaged oil in newborns and to specifically compare the effects of (i) essential fatty acid (EFA) rich - safflower oil and (ii) saturated fat rich coconut oil, on fatty acid profiles of massaged babies. DESIGN:A short term randomised controlled study. ...
journal_title:Indian pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2005-10-01 00:00:00
abstract::Madhya Pradesh has made remarkable progress in facility based management of severe acute malnutrition, and has developed a model that is being replicated in many states. India has uniquely high prevalence of both stunting and wasting, implying that both severe acute malnutrition and severe chronic malnutrition co-exis...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-014-0341-z
更新日期:2014-02-01 00:00:00
abstract:BACKGROUND:Lysinuric protein intolerance is an inherited disorder of transport of cationic amino acids, causing amino aciduria. CASE CHARACTERISTICS:A 3-year-old boy with 12 month history of episodic change in behavior (decreased sleep, poor interaction), stunted growth and hyperammonemia. OUTCOME:Genetic analysis re...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-016-0920-2
更新日期:2016-08-08 00:00:00
abstract::We conducted this study to ascertain whether health workers can routinely administer verbal autopsy (VA) to determine the cause of death in their area. The health workers were trained to administer verbal autopsy tool on the deaths occurring in the population under them. All the verbal autopsies of under-five deaths b...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2003-08-01 00:00:00
abstract::Trichotillomania, though uncommon, is one of the causes of unexplained hair loss, especially in children. Three girls in the age group of 4-6 years were observed in our pediatric dermatology clinic to have trichotillomania. In one child, there was co-existent alopecia areata. All were referred to the child guidance cl...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00