Abstract：
OBJECTIVE:To evaluate endothelial function and arterial mechanics in apparently healthy overweight adolescents. DESIGN:Analytical observational study. SETTING:Tertiary hospital. METHODS:40 asymptomatic, normotensive and non-smoking adolescents (11 to 18 years old) were evaluated. Of these 20 were overweight or obese as per International Obesity Task Force criteria while 20 were controls. High resolution ultrasonography was performed to measure flow mediated and Glyceryltrinitrate induced dilation in brachial artery, and arterial mechanics in common carotid artery. RESULTS:Overweight adolescents had significantly lower ratio of flow mediated dilation to Glyceryltrinitrate mediated dilation (0.40 plusminus 0.41 versus 0.61 plusminus 0.17; P = 0.039). On age and sex adjusted multiple regression analysis, the ratio of flow mediated to Glyceryltrinitrate mediated dilation had a significant negative association with body mass index (P = 0.012) and mean skin fold thickness (P = 0.011). However, for mean skin fold thickness, flow mediated dilation also had a significant negative association (P = 0.027). None of the measures of arterial mechanics were significantly different amongst overweights and controls, or significantly associated with either body mass index or mean skin fold thickness. CONCLUSION:Endothelial function can be mildly impaired in apparently healthy adolescents who are overweight (assessed by body mass index) or adipose (assessed by skin fold thickness). The use of overweight for screening adolescents likely to develop coronary artery disease is therefore justified. Skin fold thickness is a better indicator than Body Mass Index for predicting endothelial function.
journal_name
Indian Pediatrjournal_title
Indian pediatricsauthors
Kumar V,Sachdev HP,Khalil Akeywords:
subject
Has Abstractpub_date
2004-11-01 00:00:00pages
1105-14issue
11eissn
0019-6061issn
0974-7559journal_volume
41pub_type
杂志文章abstract：:Three hundred and fifty stool samples from patients with acute diarrhea and 30 samples from normal healthy controls were examined for the presence of various parasitic and bacterial enteropathogens by conventional techniques. Cryptosporidium oocysts were detected in 15 out of 350 (4.3%) fecal samples. In 10 cases (2.9...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1991-08-01 00:00:00
abstract：:One hundred ninety one children below 5 years of age suffering from poliomyelitis were analyzed to find out the immunization status and its correlation with the incidence of poliomyelitis. Effects of age, sex, immunization status and seasonal variation on the morbidity and mortality status were studied. The maximum nu...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1991-06-01 00:00:00
abstract：:This study is a retrospective analysis of 670 cases of poisoning (including phenothiazine toxicity) admitted to this hospital in the past six years, accounting for 0.9% of all pediatric admissions. Nearly half (45%) of the cases were in the age group of 1-4 years. Medicines and chemicals were the commonest agents (53%...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1991-05-01 00:00:00
abstract：OBJECTIVE:To evaluate the effect of clofibrate for unconjugated hyperbilirubinemia in neonates. METHODS:A systematic review with meta-analysis of randomized controlled trials or quasi-randomized controlled trials was conducted to evaluate the clofibrate treatment in neonates with unconjugated hyperbilirubinemia. We fo...
journal_title：Indian pediatrics
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s13312-012-0012-x
更新日期：2012-01-01 00:00:00
abstract：:We report Hemolytic Uremic Syndrome (HUS) induced by Streptococcus pneumoniae in a 20 month-old girl. She responded well to hemodialysis. ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2007-05-01 00:00:00
abstract：:This study was conducted in 2006 to assess the current iodine nutriure of the population in Haryana by assessing the urinary iodine excretion levels amongst the school age children between 6-12 years. Altogether 3,019 urine samples were collected from all the 19 districts in Haryana. The urinary iodine was analyzed by...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2009-01-01 00:00:00
abstract：:Pathologic fractures in children may be due to various causes. Rarely, it may be the presenting symptom of neurofibromatosis. A misdiagnosis of Rickets and Vitamin D supplementation in such a case may wreak havoc in the form of iatrogenic hypervitaminosis D. We report one such case. ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-010-0137-8
更新日期：2010-10-01 00:00:00
abstract：OBJECTIVE:To evaluate the efficacy and tolerability of intravenous fosphenytoin in children with status epilepticus, and resulting serum total phenytoin levels. METHODS:In this prospective study, 51 children aged less than 18 years received intravenous loading dose of fosphenytoin (18-20 mg/kg). Serum total phenytoin ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2020-03-15 00:00:00
abstract：:A cross sectional study was conducted in 260 adolescent schoolchildren (114 males) in the age group of 11-18 years to estimate the prevalence of zinc deficiency in the National Capital Territory of Delhi. Serum zinc was estimated using Inductively coupled plasma mass spectrometer. Overall, 49.4% children (50.8% males,...
journal_title：Indian pediatrics
pub_type： 信件
doi：
更新日期：2011-12-01 00:00:00
abstract：OBJECTIVE:To assess the glycometabolic function in chronically transfused patients of beta- thalassemia major in terms of glucose tolerance, insulin secretion, insulin resistance index, and beta cell function index and to determine their relationship with clinical and biochemical profile. METHODS:30 homozygous thalass...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2006-05-01 00:00:00
abstract：OBJECTIVE:To study the association between common AIDS restriction genes and slow disease progression among perinatally-infected children in India. METHODS:ART-naïve children were identified and selected host factors including CCR5-∆32, SDF1-3'A, CCR5-59029G, HLA-B*27, B*57 were studied using allele-specific PCR-RFLP ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-014-0505-x
更新日期：2014-10-01 00:00:00
abstract：:Trichotillomania, though uncommon, is one of the causes of unexplained hair loss, especially in children. Three girls in the age group of 4-6 years were observed in our pediatric dermatology clinic to have trichotillomania. In one child, there was co-existent alopecia areata. All were referred to the child guidance cl...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：:A major purpose of the immunization coverage evaluation surveys to document the vaccination status of children aged 1-2 years was to determine the true picture of the immunization status of the target population and to identify areas which need strengthening. Immunization coverage evaluation surveys were carried out f...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1990-04-01 00:00:00
abstract：OBJECTIVE:To improve the rates of first hour initiation of breastfeeding in neonates born through cesarean section from 0 to 80% over 3 months through a quality improvement (QI) process. DESIGN:Quality improvement study. SETTING:Labor Room-Operation Theatre of a tertiary care hospital. PARTICIPANTS:Stable newborns ≥...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2018-09-15 00:00:00
abstract：:Highly active antiretroviral therapy is beyond reach of most HIV-infected children in developing countries. There is paucity of data on more affordable regimens such as ones based on nevirapine and 2 nucleoside reverse transcriptase inhibitors. We report our experience with the use of antiretroviral therapy in childre...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2005-08-01 00:00:00
abstract：OBJECTIVE:To study the relationship of CSF IL-1 beta and TNF-alpha with free radicals in acute bacterial meningitis (ABM) and to evaluate the clinical outcome in relation to the levels of these cytokines and free radicals in CSF. DESIGN:Prospective with controls. SETTING:Referral unit of a teaching hospital. METHODS...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2000-06-01 00:00:00
abstract：BACKGROUND:Lysinuric protein intolerance is an inherited disorder of transport of cationic amino acids, causing amino aciduria. CASE CHARACTERISTICS:A 3-year-old boy with 12 month history of episodic change in behavior (decreased sleep, poor interaction), stunted growth and hyperammonemia. OUTCOME:Genetic analysis re...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-016-0920-2
更新日期：2016-08-08 00:00:00
abstract：:Anthropometric data from our survey of 1,879 children in Madhya Pradesh revealed low sensitivity (17.5%) and positive predictive value (30.4%) of Mid-Upper Arm Circumference (MUAC) at the recommended cut-off of 115 mm for identifying Severe Acute Malnutrition (SAM). This led us to question the reliability of MUAC as a...
journal_title：Indian pediatrics
pub_type： 信件
doi：10.1007/s13312-013-0032-1
更新日期：2013-01-08 00:00:00
abstract：:In a randomized controlled design, 100 healthy, term neonates in the first week of life, undergoing heel prick for routine screening were randomized to receive a heel prick in either the drowsy/sleeping state or the awake (but not fussy or crying) state. 48 babies in sleeping or drowsy states and 47 in the awake state...
journal_title：Indian pediatrics
pub_type： 杂志文章,随机对照试验
doi：10.1007/s13312-011-0082-1
更新日期：2011-05-01 00:00:00
abstract：:Avian flu is affecting the poultry animals world over since first outbreak in 1997 in Hong Kong and has resulted in 92 human deaths and culling of more than 150 million poultry animals in Asia and Europe. The loss to the economy has also been enormous. 13 new countries, including India, reported occurrence of the dise...
journal_title：Indian pediatrics
pub_type： 杂志文章,评审
doi：
更新日期：2006-04-01 00:00:00
abstract：:Ninety neonates were ventilated over a period of 33 months of whom 50 (55.5%) survived. Fifty seven babies received IPPV while 33 CPAP. IPPV mode was being used more frequently recently and survival rates have steadily improved over past 3 years. Survival was cent per cent in babies above 1.5 kg on CPAP mode while 16/...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1993-06-01 00:00:00
abstract：OBJECTIVE:To describe a novel wrist deformity in b-thalassemia major patients, and their radiographic and magnetic resonance imaging findings. METHODS:30 patients with b-thalassemia major who were noticed to have ulnar deviation at wrist joint were evaluated for previous history of medications, serum ferritin levels, ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2019-01-15 00:00:00
abstract：:Beta thalassemia is a common genetic disorder in Indians. Around 10,000 thala-ssemia major cases are born every year. The treatment of thalassemia major patients imposes a financial burden on the family. Much progress has been made in last 15 years in understanding of the pathogenesis of thalassemia and development of...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2006-06-01 00:00:00
abstract：:Pulmonary manifestations of sarcoidosis are common and may be initially confused with other common diseases like tuberculosis. We report an 11 yr old girl who presented with chronic cough, low grade fever, recent exposure to tuberculosis and hilar lymphadenopathy. She was provisionally diagnosed as pulmonary tuberculo...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2007-08-01 00:00:00
abstract：CONTEXT:Measles remains a major cause of child mortality in India. Measles case fatality ratios (CFRs) vary substantially between countries and even within the same community over time. We present a review of Indian community-based measles CFR studies conducted from 1975 to 2008. EVIDENCE ACQUISITION:PubMed, Cochrane ...
journal_title：Indian pediatrics
pub_type： 杂志文章,评审
doi：
更新日期：2009-11-01 00:00:00
abstract：:Patent ductus arteriosus (PDA) is a major morbidity in preterm infants, especially in extremely premature infants less than 28 weeks. The clinical signs and symptoms of PDA in preterm infants are non specific and insensitive for making an early diagnosis of significant ductal shunting. Functional echocardiography is e...
journal_title：Indian pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s13312-011-0062-5
更新日期：2011-04-01 00:00:00
abstract：:There is little published literature from the third World countries that described the factors influencing survival of babies with esophageal atresia. We analysed 25 consecutive neonates treated for esophageal atresia. The overall survival rate was 36%. All 4 babies in Waterston Group A, 37.5% in Group B, and 15.4% in...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：OBJECTIVE:To compare the mycobacteriological yield from gastric lavage (GL) and bronchoalveolar lavage (BAL), in children with pulmonary tuberculosis. METHODS:58 consecutive children with chest radiograph suggestive of tuberculosis and positive Mantoux test or a positive history of family contact with a case of tuberc...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：
更新日期：2000-09-01 00:00:00
abstract：OBJECTIVES:To develop age and gender specific waist circumference references for urban Indian children aged 3 -16 years. DESIGN:Cross-sectional study. SETTING:Urban preschools and schools of Bangalore. PARTICIPANTS:9060 children (5172 boys and 3888 girls) in the age group of 3-16 years. METHODS:Weight, height, and ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-011-0126-6
更新日期：2011-10-01 00:00:00
abstract：:A holistic approach in assessment and plan for intervention in childhood malnutrition is the need of the hour. This is in the context of nutrition education program (NEP), undertaken under the National IAP action plan, 2015. In the crusade against malnutrition, an ABCDEFQ assessment scale is recommended, with aspects ...
journal_title：Indian pediatrics
pub_type： 杂志文章
doi：10.1007/s13312-016-0820-5
更新日期：2016-03-01 00:00:00
